Basic Information

Insect: Drosophila neoperkinsi
Gene Symbol: -
Assembly: GCA_037043555.1
Location: JBAMBG010008296.1:34299-38444[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.2e-05 0.0067 16.8 0.1 1 23 149 172 149 172 0.96

2 14 0.0014 0.11 13.1 2.9 2 23 221 243 217 243 0.89

3 14 0.012 0.91 10.1 0.9 1 23 362 385 362 385 0.93

4 14 0.15 11 6.7 5.5 2 23 434 456 433 457 0.95

5 14 0.0033 0.24 12.0 0.5 1 23 520 543 520 543 0.88

6 14 7.6 5.5e+02 1.4 0.0 2 13 562 573 561 578 0.81

7 14 0.00069 0.051 14.1 3.3 2 23 594 616 594 616 0.96

8 14 0.00079 0.058 13.9 0.1 1 23 727 750 727 750 0.95

9 14 8.9e-05 0.0065 16.9 0.2 1 23 799 822 799 822 0.94

10 14 0.0012 0.085 13.4 2.2 2 23 872 894 871 894 0.97

11 14 0.0024 0.18 12.4 1.4 1 23 981 1004 981 1004 0.91

12 14 0.049 3.5 8.3 2.3 1 21 1056 1076 1056 1077 0.95

13 14 0.031 2.3 8.9 0.6 3 23 1117 1140 1116 1140 0.96

14 14 6 4.4e+02 1.7 0.4 1 20 1158 1179 1158 1182 0.61

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.2e-05	0.0067	16.8	0.1	1	23	149	172	149	172	0.96
2	14	0.0014	0.11	13.1	2.9	2	23	221	243	217	243	0.89
3	14	0.012	0.91	10.1	0.9	1	23	362	385	362	385	0.93
4	14	0.15	11	6.7	5.5	2	23	434	456	433	457	0.95
5	14	0.0033	0.24	12.0	0.5	1	23	520	543	520	543	0.88
6	14	7.6	5.5e+02	1.4	0.0	2	13	562	573	561	578	0.81
7	14	0.00069	0.051	14.1	3.3	2	23	594	616	594	616	0.96
8	14	0.00079	0.058	13.9	0.1	1	23	727	750	727	750	0.95
9	14	8.9e-05	0.0065	16.9	0.2	1	23	799	822	799	822	0.94
10	14	0.0012	0.085	13.4	2.2	2	23	872	894	871	894	0.97
11	14	0.0024	0.18	12.4	1.4	1	23	981	1004	981	1004	0.91
12	14	0.049	3.5	8.3	2.3	1	21	1056	1076	1056	1077	0.95
13	14	0.031	2.3	8.9	0.6	3	23	1117	1140	1116	1140	0.96
14	14	6	4.4e+02	1.7	0.4	1	20	1158	1179	1158	1182	0.61

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCTGACTTTGAAGAGGCTGATGCTGGGCCAAAGAGTCACAGTTATGCAGACGAGTTTATGGGCGATGAGGATGCGGATGAGCAAGAgactgctgatgatgatgttgatgctgtgAAAGGACCTGAGCCAGATGACGATGccatatttgattttgaacTGGAGCCAATTGTTAGCATTGCGGAACCCGAACCAGCACCCAGACCAACTGTCCGATTGGCGCCACCAATGCCGGTTGCTCCGCCCGTTCGGCCCCAGCAGCATCATCTTCCGTCAACGGTTAGCTCCACTTCCTCCTCCATGATGGGAGGTCGCGGTGGTGCTGCCGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAATGGAGTGCCCATTAACTATGAACTAGGCGTCATCTATATATGCCCGGCTTGTGGTGCCGAGTTCCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGTCTCAACTTTGTTGGAATTGATAAACTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCACAGCCGGGAGAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGACAAGACCTGATGGTGCATCTGCGCATGGTACACTGTGACGAGGTGGTTGCCATGATGCGTGCCGGTGATGCCAGTGCTGGGCGCAAGACGCGAGTCCGTGAGCCGCGCGTCGAGCAGCGTGCTCATGGTGCGTCTCGGTTCGGGCCGATCAGCCATGGACCGGTTCgtgacgatgatgatggtaTCGAGGTCAAGAATGAGCTGATGGACACGGAAGCAACGGCTGCAACGGCTGCCGATGACGTGGTTGACGAGCCAAATCGCAGCTTCAACCAAGCAAAGAAGAAGCGTATTAATCAGTCGGCCGGCTCTGCAAACGCTGGCAAAGCCGACAACGACAGTGGCAGTGGCGGCGGCGCTTCGGATATCTGCGAAGATTATATACACTACATGTGTCCCGATTGCGGCACCGACTGCGACACGCACGCTCAGTGGAGCCAGCACATTGAATTCGTGCACGACTATGTCAGCCGGCGGGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATCAAGACACTGCGCGCACACAAATTCAGTCATTTGGCTCAGCCGGATTGGATGCGTTGCAAGCTGTGCTATCGGGGTTATACGGATCATCATGAGCTGGTCACGCACCTGCTCAAGCAGCATCATCTGGAGACATTAATGCCCGaagaggagcaggagcagcaaacGGTCAGTGCCAGTGCCGTCGATGATGCTGAGGATAACTCTGGCATCGGCAATGGCTGCGATGATGAATCCCTGTTGCAATTTGAGGATGTGCCCCGTCGTGGCGGTCGCATTGGCGGCGATGATATGTATGAGCCGCACATTGATTATCTGTGCCCGCAGTGCGGCCGCGAGTTCATTGAGAAGAAGCACTGGCGCACGCATGTTGTCCAGGTGCATGGCATGAACGATCTGGCCAAGCTGAACTTTGAGGTCATCAACGATCGTCAGCTGAAATGCACAGAATGCGAGAAGATCATCACGAATGCCTACGGCATTCAGAATGCTCAACAACACCGGATTACTCATTTGCCCTACAAGGCATATGCGCGCTGTcgcaaatgccacaaatcgTATACGGATCGCAAGGGTCTGGTTAAGCACTTGGCCACATACCATTGCGTCGGCTATGAACCGCGCAATTCCGGTGCTGGAGGAGCGGCAGTCGGTGCAGGACAGAGCCAGGCCAAGTCGCAAACGCCGCGCAAACAAATTGTTACTGTTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGAGCAATCACCgccaaataacaataatattaatgaggAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGATGACTATGCCACCAGCTGCACCAGCACACGCCAGTTGCCACCAGCtactgcggctgcggctgctgctgctgctgctgccgccacaACCTCTGCGTCCAATCAAAATGTGAATCGTTATAAATGCGTTGATTGCGGCTCCCTGTTTGCCACGCAGGCGGCGCTCAAGACGCACATTAGCGAGGAGCATGATTTTATGGACACGCAGTATAGCGCTAAAAAGTTTGATAATGCCGAACACGCAGAGGAGACGACGCCAGCGGCAGCGTCCGTGGCGGCCACTTCGCCTCCCAAAATCTTTTCTGGCGGCTCGACAATCGAacagaattatatatatttgtgcccCTCCTGCGGCAAGCCATATAAGACGCAATTCGAGTGGCGTCGCCACATCAACGAGGAGCACAATTTTGATAAGCGGCAATATTTGAATATGCGCCAGCTGGACAAGTATCGTTATCAGTGCACTCAGTGCAAGGACATTGTGAGCAATTCGAAGCTAAAGGGACTGCAGGATCATCACTTCAGACACTTGCCCTATAGGCTCTACTTAAAGTGCCTCGTTTGCGGCACCTGCTACAATCACAAGCCCAACATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGTGAAATGCAGCCGAAGCCTCAGAATGGCTATGACACCATCAAATATAAAGATAAGGATATGCCAGTCATGTCCGCCACGACGTCAGACTCGCCGACgcctggcagcagcagtaacagtgCTCGCTCACTGAAACCGCAGCCCGGTTTGCTGCCCATGCGACCCGCGGGCCTAAACACACTGGAGGATAGCATCTCCTATCACAATGCTGTCGATTTGGACTTTATTACCTACTTCTGCCCCGAGTGCAATAAGAACTTTGATTCGCACGCTTTCTGGCGCAAACACATTGTCGAGCAGCACAACTTCAACAGCCGGCAAGGCTTGAACTTTCGCCAGATCGACAATCATCACTATCTGTGCCTGGAGTGCTACAAGCGGGTGACGGTTACCCACACCAAGGGCGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGACATCTTCCCTATCGCTCATTTAAGTGCTTGACCTGCAACGGCAAATTTGTgcgaaaacaaatgtttttcaagCATTTGAACCGTGACACAAATCGCTGCGATAGCGGAGATCATAGTAACGAGGAACACATCTCCGAGCAGCCGGAGGAGAGATCTTCGTCCGCAAACGATGCATCTGATGCCGCCTCGTATCGCTTGCTGTGCCCGCAGTGCGGCGATAACTtcagcaccagcaccaaatcCCTCTGGCGTAAGCATATTAATACTCAACATGGTCTGAGCAAGCTGGAGGTGCTGCACATGTCCAAGCTGGGCGACGAGCTCTATCGCTGCGTGGACTGTGATGAGCAGCTGGAAACGAAACAGCTGCGTGTGCTGCAACAGCATCGCTTCCGCCATTTACCCTATGCCGCCTACATACGTTGCCAGCTGtgcgagcaacagcagccggatGAACTGGGTCATGGTCCCGTTGCAGCCGGGATGCACAGCATGTGTGAGCTGCAGCAACACATGCGCGACGAGCATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTGCTCGTCGATGTGGACGATGAGGAAAGCCACCCGATGGCGGTGGCAAGCAATGAGGCATCTGACAATGGGTCATATATGCCGATGCCGCTGCAAATGCTCCTCGACggcgatgaggatgaggacaGCCAAACGGCGGCAGCTAACAATGAGACGTCCGACAATGGACCATATATGCCCCTGCCGCCGCATTTACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGATCAATATCTACTGAGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEADAGPKSHSYADEFMGDEDADEQETADDDVDAVKGPEPDDDAIFDFELEPIVSIAEPEPAPRPTVRLAPPMPVAPPVRPQQHHLPSTVSSTSSSMMGGRGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVGIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRVEQRAHGASRFGPISHGPVRDDDDGIEVKNELMDTEATAATAADDVVDEPNRSFNQAKKKRINQSAGSANAGKADNDSGSGGGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYRGYTDHHELVTHLLKQHHLETLMPEEEQEQQTVSASAVDDAEDNSGIGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHCVGYEPRNSGAGGAAVGAGQSQAKSQTPRKQIVTVANETYEIIYLDDEQSPPNNNNINEENDFGEQMQADDDDYATSCTSTRQLPPATAAAAAAAAAAATTSASNQNVNRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEETTPAAASVAATSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDTIKYKDKDMPVMSATTSDSPTPGSSSNSARSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPECNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGKFVRKQMFFKHLNRDTNRCDSGDHSNEEHISEQPEERSSSANDASDAASYRLLCPQCGDNFSTSTKSLWRKHINTQHGLSKLEVLHMSKLGDELYRCVDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPVAAGMHSMCELQQHMRDEHPSFVENDEQMQLLVDVDDEESHPMAVASNEASDNGSYMPMPLQMLLDGDEDEDSQTAAANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -