Basic Information

Insect: Drosophila silvestris
Gene Symbol: -
Assembly: GCA_035043445.1
Location: JAWNMZ010000151.1:7601749-7605850[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.7e-05 0.0064 16.8 0.1 1 23 149 172 149 172 0.96

2 14 0.0015 0.1 13.1 2.9 2 23 221 243 217 243 0.89

3 14 0.013 0.87 10.1 0.9 1 23 362 385 362 385 0.93

4 14 0.066 4.4 7.9 4.5 2 23 434 456 433 457 0.95

5 14 0.0035 0.23 12.0 0.5 1 23 520 543 520 543 0.88

6 14 8 5.3e+02 1.4 0.0 2 13 562 573 561 578 0.81

7 14 0.00073 0.049 14.1 3.3 2 23 594 616 594 616 0.96

8 14 0.00084 0.055 13.9 0.1 1 23 722 745 722 745 0.95

9 14 9.4e-05 0.0062 16.9 0.2 1 23 794 817 794 817 0.94

10 14 0.0012 0.081 13.4 2.2 2 23 867 889 866 889 0.97

11 14 0.0026 0.17 12.4 1.4 1 23 976 999 976 999 0.91

12 14 0.051 3.4 8.3 2.3 1 21 1051 1071 1051 1072 0.95

13 14 0.033 2.2 8.9 0.6 3 23 1112 1135 1111 1135 0.96

14 14 6.4 4.2e+02 1.7 0.4 1 20 1153 1174 1153 1177 0.61

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.7e-05	0.0064	16.8	0.1	1	23	149	172	149	172	0.96
2	14	0.0015	0.1	13.1	2.9	2	23	221	243	217	243	0.89
3	14	0.013	0.87	10.1	0.9	1	23	362	385	362	385	0.93
4	14	0.066	4.4	7.9	4.5	2	23	434	456	433	457	0.95
5	14	0.0035	0.23	12.0	0.5	1	23	520	543	520	543	0.88
6	14	8	5.3e+02	1.4	0.0	2	13	562	573	561	578	0.81
7	14	0.00073	0.049	14.1	3.3	2	23	594	616	594	616	0.96
8	14	0.00084	0.055	13.9	0.1	1	23	722	745	722	745	0.95
9	14	9.4e-05	0.0062	16.9	0.2	1	23	794	817	794	817	0.94
10	14	0.0012	0.081	13.4	2.2	2	23	867	889	866	889	0.97
11	14	0.0026	0.17	12.4	1.4	1	23	976	999	976	999	0.91
12	14	0.051	3.4	8.3	2.3	1	21	1051	1071	1051	1072	0.95
13	14	0.033	2.2	8.9	0.6	3	23	1112	1135	1111	1135	0.96
14	14	6.4	4.2e+02	1.7	0.4	1	20	1153	1174	1153	1177	0.61

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCTGACTTTGAAGAGGCTGATGCTGGGCCAAAGAGTCACAGTTATGCAGACGAGTTTATGGGCGATGAGGATGCGGATGAGCAGGAgacagctgatgatgatgttgatgctggGAAAGGACCTGAGCCAGATGACGATgccatatttgattttgaactGGAGCCAATTGTAAGCATTGCGGAACCCGAACCAGCACCCAGACCAACTGTCCGATTGGCGCCACCAATGCCGGTTGCTCCGCCCGTTCGGCCCCAGCAGCATCATCTTCAGTCAACGGTTagctccacctcctcctccatgATGGGAGGTCGCGGTGGTGCTGCCGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGAGTGCCCATTAACTATGAACTGGGCGTCATCTACATATGCCCGGCTTGTGGTGCCGAGTTCCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGCCTCAACTTTGTTGCAATTGATAAACTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCACAGCCGGGAGAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAACGCGAGTACAAGTACAGACAAGACCTGATGGTGCATCTGCGCATGGTACACTGTGACGAGGTGGTTGCCATGATGCGTGCCGGTGATGCCAGTGCTGGACGCAAGACGCGAGTCCGTGAGCCGCGCGTCGAGCAGCGTGCTCATGGTGCGTCTCGGTTCGGGCCGATCAGCCATGGACCGGTTCgtgacgatgatgatggtaTCGAGGTCAAGAATGAGCTGATGGACACGGAAGCAACGGCTGCGACGGCTGCCGATGACGTCGTTGACGAGCAGAATCACAGCTTCAACCAAGCAAAGAAGAAGCGTATTAATCAGTCGGCCGGCTCTGCAAACGCTGGCAAAGCCGACAACGACAGTGGCAGTGGTGGCGGCGCTTCGGATATCTGCGAAGATTACATACACTACATGTGTCCCGATTGCGGCACCGACTGCGACACGCACGCTCAGTGGAGCCAGCACATTGAATTCGTGCACGACTATGTCAGCCGGCGGGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATCAAGACACTGCGCGCACACAAATTCAGTCATTTGGCTCAGCCAGATTGGATGCGTTGCAAGCTGTGCTATCGGGGTTATACGGATCATCATGAGCTGGTCGCGCACCTGCTCAAGCAGCATCATCTGGAGACATTAATGCCCgaagaggagcaggagcagcaaacGGTCAGTGCCAGTGCCGGCGATGATGCTGAGGATAACTCTGGCATCGGCAATGGCTGCGATGATGAATCCCTGTTGCAATTTGAGGATGTGCCCCGTCGTGGCGGCCGCATTGGCGGCGATGATATGTATGAGCCGCACATTGATTATCTGTGCCCGCAGTGCGGACGCGAGTTCATTGAGAAGAAGCACTGGCGCACGCATGTTGTCCAGGTGCATGGCATGAACGATCTGGCCAAGCTGAACTTTGAGGTCATCAACGATCGTCAGCTGAAATGCACAGAATGCGAGAAGATCATCACGAATGCCTACGGCATTCAGAATGCTCAACAACACCGGATTACTCATTTGCCCTACAAGGCATATGCGCGCTGTcgcaaatgccacaaatcgTATACGGATCGCAAGGGTCTGGTTAAGCACTTGGCCACATACCATTGCGTCGGCTATGAACCGCGCAATTCCGGTGCTGGAGGAGCGGCAGTCGGTGCAGGACAGAGCCAGGTCAAGTCACAAACGCCgcgcaaacaaattgttactGTTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGAGCAATCCCCgccaaataacaataatattaatgaggAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGATGACTATGCCACAGGCTGCACCAGCACACGCCAGTTGCCACCAGctactgcggctgctgctgctgccacaaccTCTGCGTCCAATCAAAATCCGAATCGTTATAAATGCGTTGATTGTGGCTCCCTGTTTGCCACGCAGGCGGCGCTCAAGACGCACATTAGCGAGGAGCACGATTTTATGGACACGCAGTATAGCGCTAAAAAGTTTGATAATGCCGAACACGCAGAGGAGACGACGCCAGCGGCAGCGTCCGTGGCGGCCACTTCGCCTCCCAAAATCTTTTCTGGCGGCTCGACAATCGAacagaattatatatatttgtgcccCTCCTGCGGCAAGCCATATAAGACGCAATTTGAGTGGCGTCGCCACATCAACGAGGAGCACAATTTTGATAAGCggcaatatttgaatatgcgCCAGCTGGACAAGTATCGTTATCAGTGCACTCAGTGCAAGGACATTGTGAGCAATTCGAAGCTAAAGGGACTGCAGGATCATCACTTCAGACACTTGCCCTATAGGCTCTACTTAAAGTGCCTAGTTTGCGGCACCTGCTACAATCACAAGCCCAACATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGTGAAATGCAGCCGAAGCCTCAGAATGGCTATGACACCATCAAATATAAAGATAAGGATATGCCAGCCATGTCCGGTACGACGTCAGACTCGCCGACgcctggcagcagcagtaacagtacTCGCTCACTGAAACCGCAGCCCGGTTTGCTGCCCATGCGACCCGCTGGCCTAAACACACTGGAGGATAGCATCTCCTATCACAATGCTGTCGATCTGGACTTTATTACCTACTTCTGCCCCGAGTGCAATAAGAACTTTGATTCGCACGCTTTCTGGCGCAAACACATTGTCGAGCAGCACAACTTCAACAGCCGGCAAGGCTTGAACTTTCGCCAGATTGACAATCATCACTATCTGTGCCTGGAGTGCTATAAGCGGGTGACAGTTACCCATACCAAGGGCGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGACATCTTCCCTATCGCTCATTTAAGTGCTTGACCTGCAACGGCAAATTTGTGCgaaagcaaatgtttttcaaGCATTTGAACCGTGACACAAATCGCTGCGACAGCGGAGATCATAGTAACGAGGAACACATCTCCGAGCAGCCGGAGGAGAGATCTTCGTCCGCAAACGATGCATCCGATGCCGCCTCGTATCGCTTGCTGTGCCCGCAGTGCGGAGATAACTTCAGCACCAGCACCAAATCCCTCTGGCGTAAGCATATTAACACTCAACATGGTCTGAGCAAGCTGGAGGTGCTGCACATGTCCAAGCTGGGCGACGAGCTCTATCGCTGCGTGGACTGCGATGAGCAGCTGGAAACGAAACAGCTGCGTGTGCTGCAACAGCATCGCTTCCGCCATTTGCCCTATGCCGCCTACATACGTTGCCAGCTCtgcgagcaacagcagccggatGAACTGGGTCATGGTCCCGTTGCAGCCGGGATGCACAGCATGTGTGAGCTGCAGCAACACATGCGCGACGAACATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTGCTCGTCGATGTGGACGATGAGGAGAGTCACCCGATGGCGGTGGCAAGCAATGAGGCATCTGACAATGGGTCATATATGCCGATGCCGCTGCAAATGCTCCTCGacggcgatgacgatgaggacAGCCAAACGGCGGCAGCTAACAATGAGACGTCCGACAATGGACCATATATGCCCCTGCCGCCGCATTTACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGACCAATATCTACTGAGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEADAGPKSHSYADEFMGDEDADEQETADDDVDAGKGPEPDDDAIFDFELEPIVSIAEPEPAPRPTVRLAPPMPVAPPVRPQQHHLQSTVSSTSSSMMGGRGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRVEQRAHGASRFGPISHGPVRDDDDGIEVKNELMDTEATAATAADDVVDEQNHSFNQAKKKRINQSAGSANAGKADNDSGSGGGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYRGYTDHHELVAHLLKQHHLETLMPEEEQEQQTVSASAGDDAEDNSGIGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHCVGYEPRNSGAGGAAVGAGQSQVKSQTPRKQIVTVANETYEIIYLDDEQSPPNNNNINEENDFGEQMQADDDDYATGCTSTRQLPPATAAAAAATTSASNQNPNRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEETTPAAASVAATSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDTIKYKDKDMPAMSGTTSDSPTPGSSSNSTRSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPECNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGKFVRKQMFFKHLNRDTNRCDSGDHSNEEHISEQPEERSSSANDASDAASYRLLCPQCGDNFSTSTKSLWRKHINTQHGLSKLEVLHMSKLGDELYRCVDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPVAAGMHSMCELQQHMRDEHPSFVENDEQMQLLVDVDDEESHPMAVASNEASDNGSYMPMPLQMLLDGDDDEDSQTAAANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -