Basic Information

Insect: Drosophila engyochracea
Gene Symbol: -
Assembly: GCA_035042385.1
Location: JAWNLK010000101.1:5293491-5297514[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.6e-05 0.0061 16.8 0.1 1 23 149 172 149 172 0.96

2 14 0.0015 0.096 13.1 2.9 2 23 221 243 217 243 0.89

3 14 0.013 0.83 10.1 0.9 1 23 359 382 359 382 0.93

4 14 0.16 10 6.7 5.5 2 23 431 453 430 454 0.95

5 14 0.0034 0.22 12.0 0.5 1 23 517 540 517 540 0.88

6 14 7.9 5e+02 1.4 0.0 2 13 559 570 558 575 0.81

7 14 0.00073 0.046 14.1 3.3 2 23 591 613 591 613 0.96

8 14 0.00083 0.053 13.9 0.1 1 23 726 749 726 749 0.95

9 14 1.5e-05 0.00095 19.4 0.8 1 23 798 821 798 821 0.95

10 14 0.0012 0.077 13.4 2.2 2 23 871 893 870 893 0.97

11 14 0.0025 0.16 12.4 1.4 1 23 980 1003 980 1003 0.91

12 14 0.051 3.2 8.3 2.3 1 21 1055 1075 1055 1076 0.95

13 14 0.033 2.1 8.9 0.6 3 23 1112 1135 1111 1135 0.96

14 14 6.3 4e+02 1.7 0.4 1 20 1153 1174 1153 1177 0.61

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.6e-05	0.0061	16.8	0.1	1	23	149	172	149	172	0.96
2	14	0.0015	0.096	13.1	2.9	2	23	221	243	217	243	0.89
3	14	0.013	0.83	10.1	0.9	1	23	359	382	359	382	0.93
4	14	0.16	10	6.7	5.5	2	23	431	453	430	454	0.95
5	14	0.0034	0.22	12.0	0.5	1	23	517	540	517	540	0.88
6	14	7.9	5e+02	1.4	0.0	2	13	559	570	558	575	0.81
7	14	0.00073	0.046	14.1	3.3	2	23	591	613	591	613	0.96
8	14	0.00083	0.053	13.9	0.1	1	23	726	749	726	749	0.95
9	14	1.5e-05	0.00095	19.4	0.8	1	23	798	821	798	821	0.95
10	14	0.0012	0.077	13.4	2.2	2	23	871	893	870	893	0.97
11	14	0.0025	0.16	12.4	1.4	1	23	980	1003	980	1003	0.91
12	14	0.051	3.2	8.3	2.3	1	21	1055	1075	1055	1076	0.95
13	14	0.033	2.1	8.9	0.6	3	23	1112	1135	1111	1135	0.96
14	14	6.3	4e+02	1.7	0.4	1	20	1153	1174	1153	1177	0.61

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCTGACTTTGAAGAGGCTGATGCTGGGTCAAAGAGTCAAAGTTATGCAGACGAGTTTATGGGCGATGATGATGCGGATGAGCAGGAgactgctgatgatgatgttgatgctggGAAACGACCTGAGCCAGATGACGATgccatatttgattttgaactgGAGCCAATTGTTAGCATTGCGGAACCCGAACCAGCGCCAAGACCAACTGTCCGATTGGCGCCACCAATGCCAGTTGCTCCGCCCGTTCGGCCCCAGCAGCATAATCTTCAGTCAACGGTTAGCTCCACTTCCTCCTCCATGATGGGAGGTCGCGGTGGTGCTACCGCGCCACCCACACGACCTACAACATCTCAAATCAATGCCACAGATGAGAACGGAGTGCCCATTAACTATGAACTGGGCGTCATCTATATATGCCCGGCTTGTGGTGCCGAGTTCCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGCCTCAACTTTGTTGGAATTGATAAGCTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCACAGCCGGGAGAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGACAGGACCTGATGGTGCATCTGCGCATGGTACACTGTGACGAGGTGGTTGCCATGATGCGTGCCGGTGACGCCAGTGCTGGACGCAAGACGCGAGTCCGTGAGCCGCGCGTTGAGCAGCGTGCTCATGGTGGGTCTCGGTTCGGGCCGATGAGCCATGGACCGGTTCgtgacgatgatgatggtaTCGAGGTCAAGAATGAGCTGATGGACACGGAAGCAACGGCTGCCGATGATGTGGTTGACGAACAGAATTGCAGCTTCAACCAAGCAAAGAAGAAGCGTATTAATCAGTCGGCTAGCTCTGCAAACGCTGGCAAAGCCGACAACGACAGTGGCAGTGGCGGCGGCGCTTCGGATATCTGCGAAGATTACATACACTATATGTGTCCCGATTGCGGCACCGACTGCGACACGCACGCCCAGTGGAGCCAGCACATTGAATTCGTGCACGACTATGTCAGCCGGCGGGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATCAAGACACTGCGCGCACACAAATTCAGTCATCTGGCTCAGCCGGATTGGATGCGTTGCAAGCTGTGCTATCGGGGTTATACGGATCATCATGAGCTGGTCACGCACCTGCTCAAGCAGCATCATCTGGAGACATTAATGCCCGaagaggagcaggagcagcaaacGGTCAGTGCCAGTGCCGGCGATGATGCTGAGGATAACTCTGGCATCGGCAATGGCTGCGATGATGAATCCCTGTTGCAATTTGAGGATGTGCCCCGTCGTGGCGGTCGTATTGGCGGCGATGATATGTATGAGCCGCATATTGATTATCTGTGCCCGCAGTGCGGCCGCGAGTTCATTGAGAAGAAGCATTGGCGCACGCATGTTGTCCAGGTGCATGGCATGAACGATCTGGCCAAGCTGAACTTTGAGGTCATCAACGATCGTCAGCTGAAATGCACAGAATGCGAGAAGATCATCACGAATGCCTACGGCATTCAGAATGCTCAGCAACACCGGATTACTCATTTGCCCTACAAGGCATATGCGCGCTGTcgcaaatgccacaaatcgTATACGGATCGCAAGGGTCTGGTTAAGCACTTGGCCACATACCATTGCGTTGGCTATGAACCGCGCAATTCCAGTGCGGGAGGAGCGGCAGTCGGTGCAGGACAGAGCCAGGTCAAGTCTCAGTCAACGCCgcgcaaacaaattgttactGTTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGAGCAATCACCgccaaataacaataatgttaATGAGGAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGATGACTATGCCACCAGTTGCACCAGCACACGCCAGTTGCCACCAGCTActgcagctgcggctgcggctgcggctgctgctgctgtcactACCTCTGCGTCCAATCAAAATGCGAATCGTTATAAATGCGTTGATTGCGGCTCCCTGTTTGCCACGCAGGCGGCGCTCAAGACGCACATTAGCGAGGAGCATGATTTTATGGACACACAGTATAGCGCTAAAAAGTTTGATAATGCCGAACACGCAGAGGAGACGACGCCAGCGGCAGCGTCTGTGGCGGCCACTTCGCCTCCCAAAATCTTTTCTGGCGGCTCGACAATCGAacagaattatatatatttgtgcccCTCCTGCGGCAAGTCATATAAGACGCAATTCGAGTGGCGTCGCCACATCAACAAAGAGCACAACTTCGATAAACggcaatatttgaatatgcgCCAGCTGGACAAGTATCGTTATCAGTGCACTCAGTGCAAGGACATTGTGAGCAATCCGAAGCTAAAGGGACTGCAGGATCATCATTTTAGACATCTGCCCTATAGGCTCTACTTAAAGTGCCTCGTTTGCGGCACCTGCTACAATCACAAGCCCAACATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGCGAAATGCAGCCGAAGCCTCAGAATGGCTATGACACCATCAAATATAAAGATAAGGACATGCCAGTCATTTCTGGCACGACGTCAGACTCGCCGACgcctggcagcagcagtaacagtgCTCGCTCACTGAAACCGCAGCCCGGTTTACTGCCCATGCGACCCGCTGGCCTAAACACACTAGAGGATAGCATCTCCTATCACAATGCTGTCGATCTGGACTTTATTACCTACTTCTGTCCCGAGTGCAATAAGAACTTTGATTCGCACGCCTTCTGGCGCAAACACATTGTCGAGCAGCACAATTTCAACAGCCGGCAAGGTTTGAACTTTCGCCAGATCGACAATCATCACTATCTGTGCCTGGAGTGCTACAAGCGGGTGACAGTCACCCACACCAAGGGCGCCATTGGGCAGCTGCAGTCTCACAAGTTCCGCCATCTTCCCTATCGCTCATTTAAGTGCTTGACCTGCAACGGCAAATTTGTGCGaaagcaaatgtttttcaaGCATTTGAACCGTGACACAAATCGCTGCGACAGCGGAGAGGAACACATCTGCGAGCAGCCGGAGGAGAGATCTTCGTCCGTAAACGATGCATCCGAGGCCGCTTCGTATCGTTTGCTGTGCCCGCAGTGCGGCGATAACttcagcaccagcaccaaaTCCCTCTGGCGTAAGCATATTAACACTCAACATGGTCTGAGCAAGCTGGAGGTGCTGCACATGTCCAAGCTGGGCGACGAGCTCTATCGCTGCGTGGACTGCGATGAGCAGCTGGAAACGAAACAGCTGCGTGTGCTACAACAGCATCGCTTCCGCCATTTGCCGTATGCCGCCTACATACGTTGCCAGCTGtgcgagcaacagcagcctgaTGAACTGGGTCATGGTCCCGTTGCAGCCGGTATGCACAGCATGTGTGAGCTGCAGCAACACATGCGCGACGAGCATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTGCTCGTCGATGTGGACGATGAGGAGAGCCACCCGATAGCGGTGGCAAGCAATGAGGCATCTGACAATGGGTCATATATGCCGATGCCGCTGCAAATGCTCCTCGACGGCGATGAGGATGAAGACAGCCAAACGGCGGCAGCTAACAATGAGACGTCCGACAACGGACCATATATGCCCCTGCCGCCGCATTTACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGATCAATATCTACTGAGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEADAGSKSQSYADEFMGDDDADEQETADDDVDAGKRPEPDDDAIFDFELEPIVSIAEPEPAPRPTVRLAPPMPVAPPVRPQQHNLQSTVSSTSSSMMGGRGGATAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVGIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRVEQRAHGGSRFGPMSHGPVRDDDDGIEVKNELMDTEATAADDVVDEQNCSFNQAKKKRINQSASSANAGKADNDSGSGGGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYRGYTDHHELVTHLLKQHHLETLMPEEEQEQQTVSASAGDDAEDNSGIGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHCVGYEPRNSSAGGAAVGAGQSQVKSQSTPRKQIVTVANETYEIIYLDDEQSPPNNNNVNEENDFGEQMQADDDDYATSCTSTRQLPPATAAAAAAAAAAAVTTSASNQNANRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEETTPAAASVAATSPPKIFSGGSTIEQNYIYLCPSCGKSYKTQFEWRRHINKEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNPKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDTIKYKDKDMPVISGTTSDSPTPGSSSNSARSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPECNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGKFVRKQMFFKHLNRDTNRCDSGEEHICEQPEERSSSVNDASEAASYRLLCPQCGDNFSTSTKSLWRKHINTQHGLSKLEVLHMSKLGDELYRCVDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPVAAGMHSMCELQQHMRDEHPSFVENDEQMQLLVDVDDEESHPIAVASNEASDNGSYMPMPLQMLLDGDEDEDSQTAAANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -