Basic Information

Insect: Drosophila grimshawi
Gene Symbol: -
Assembly: GCA_018153295.1
Location: JAECXY010000311.1:15743070-15748029[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 8.4e-05 0.0055 16.8 0.1 1 23 149 172 149 172 0.96

2 14 0.0013 0.086 13.1 2.9 2 23 221 243 217 243 0.89

3 14 0.011 0.75 10.1 0.9 1 23 359 382 359 382 0.93

4 14 0.073 4.7 7.6 5.8 2 23 431 452 430 453 0.95

5 14 0.003 0.2 12.0 0.5 1 23 517 540 517 540 0.88

6 14 7 4.5e+02 1.4 0.0 2 13 559 570 558 575 0.81

7 14 0.00064 0.041 14.1 3.3 2 23 591 613 591 613 0.96

8 14 0.00073 0.047 13.9 0.1 1 23 723 746 723 746 0.95

9 14 8.2e-05 0.0053 16.9 0.2 1 23 795 818 795 818 0.94

10 14 0.0011 0.07 13.4 2.2 2 23 868 890 867 890 0.97

11 14 0.0022 0.15 12.4 1.4 1 23 977 1000 977 1000 0.91

12 14 0.045 2.9 8.3 2.3 1 21 1052 1072 1052 1073 0.95

13 14 0.2 13 6.2 0.5 3 23 1113 1136 1112 1136 0.95

14 14 5.6 3.6e+02 1.7 0.4 1 20 1154 1175 1154 1178 0.61

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	8.4e-05	0.0055	16.8	0.1	1	23	149	172	149	172	0.96
2	14	0.0013	0.086	13.1	2.9	2	23	221	243	217	243	0.89
3	14	0.011	0.75	10.1	0.9	1	23	359	382	359	382	0.93
4	14	0.073	4.7	7.6	5.8	2	23	431	452	430	453	0.95
5	14	0.003	0.2	12.0	0.5	1	23	517	540	517	540	0.88
6	14	7	4.5e+02	1.4	0.0	2	13	559	570	558	575	0.81
7	14	0.00064	0.041	14.1	3.3	2	23	591	613	591	613	0.96
8	14	0.00073	0.047	13.9	0.1	1	23	723	746	723	746	0.95
9	14	8.2e-05	0.0053	16.9	0.2	1	23	795	818	795	818	0.94
10	14	0.0011	0.07	13.4	2.2	2	23	868	890	867	890	0.97
11	14	0.0022	0.15	12.4	1.4	1	23	977	1000	977	1000	0.91
12	14	0.045	2.9	8.3	2.3	1	21	1052	1072	1052	1073	0.95
13	14	0.2	13	6.2	0.5	3	23	1113	1136	1112	1136	0.95
14	14	5.6	3.6e+02	1.7	0.4	1	20	1154	1175	1154	1178	0.61

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCTGACTTTGAAGAGGCTGATGCTGGGCCAAAAAGTCACAGTTATGCAGACGAGATTATGGGCGATGATGCTGCGGATGAGCAGGAGACTGCTGAAGATGATGTTGATGCTGGGAAAGGACCTGAGCCAGATGACGATGCCATATTTGATTTTGAACTGGAGCCAATTGTTAGCATTGCGGAACCCGAACCAGCGCCAAGACCAACTGTCCGATTAGCGCCACCAATGCCAGTTGCTCCGCCCGTTCGGCCCCAGCAGCATAATCTTCAGTCAACGGTTAGCTCCACCTCATCCTCCATGATGGGAGGTCGCGGTGGTGCTGCCGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGAGTGCCCATTAACTATGAACTGGGCGTCATCTATATATGCCCGGCTTGTGGTGCCGAGTTCCGGCAACAGGACATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGCCTCAACTTTGTTGCAATTGATAAGCTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCACAGCCGAGAGAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGACAGGACCTGATGGTGCATCTGCGCATGGTGCACTGTGACGAGGTGGTTGCCATGATGCGTGCCGGTGACGCCAGTGCTGGACGCAAGACGCGAGTCCGTGAGCCGCGATTCGAGCAGCGTGCTCATGGTGCGTCTCGGTTCGGGCCGATGAGCCATGGACCGGTTCGTGACGATGATGATGGTATTGAAGTCATGAATGAGCTGATGGACACGGAACCAACGGCTGCCGATGATGTGGTTGACGAGCAGAATCGCAGCTTCAACCAAGGAAAGAAGAAGCGTATTAATCAGTCGGCCGGCTCTGCAAACGCTGGCAAAGCCGACAACGACAGTGGCAGTGGCGGCGGCGCTTCGGATATCTGCGAAGATTACATACACTACATGTGTCCCGATTGCGGCACCGACTGCGACACGCACGCCCAGTGGAGCCAGCACATTGAATTCGTGCACGACTATGTCAGCCGGCGGGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATCAAGACACTGCGCGCACACAAATTCAGTCATTTGGCTCAGCCGGATTGGATGCGTTGCAAGCTGTGTTATCGGGGTTATACGGATCATCATGAGCTGGTCACGCATCTGCTCAAGCATCATCATCTGGAGACATTAATGCCCGAAGAGGAGCAGGAGCAGCAAACGGTCAGTGCCAGTGCCGGCGATGATGCTGAGGATAACTCTGGCATCGGCAATGGCTGCGATGATGAATCCCTCTTGCAATTTGAGGATGTGCCTCGTCGTGGCGGTCGCATTGGCGGCGATGATATGTATGAACCGCATATTGATTATCTGTGCCCGCAGTGCGGCCGCGAGTTCATTGAGAAGAAGCATTGGCGCACGCATGTTGTCCAGGTGCATGGCATGAACGATCTGGCCAAGCTGAACTTTGAAGTCATCAACGATCGTCAGCTGAAATGCACAGAATGCGAGAAGATCATCACGAACGCCTACGGCATTCAGAATGCTCAGCAACACCGGATTACTCATCTGCCCTACAAGGCATATGCGCGCTGTCGCAAATGCCACAAATCGTATACGGATCGCAAGGGTCTGGTTAAGCACTTGGCCACATACCATTGCGTTGGCTATGAACCGCGCAATTCCAGTGCGGGAGGAGCGGCAGTCGGTGCAGGACAGAGCCAGGTCAAGTCTCAGTCAACGCCGCGCAAACAAATTGTTACTGTTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGAGCAATCACCGCCAAATAACAATAATGTTAATGAGGAGAATGATTTTGGCGAGCAGATGCAAGCCGATGATGATGACTATGCCACCAGCTGCACAAGCACACGCCAGTTGCCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTCCAATCAAAATGCGAATCGTTATAAATGCGTTGATTGCGGCTCCCTGTTTGCCACGCAGGCGGCGCTCAAGACGCACATTAGCGAGGAACATGATTTTATGGACACGCAGTATAGCGCTAAAAAGTTTGATAATGCCGAACACGCAGAGGAGACGAAGCCAGCGGCAGCGTCTGTGGCTGCTACTTCGCCTCCCAAAATCTTTTCTGGCGGCTCGACAATCGAACAGAATTATATATATTTGTGCCCCTCCTGCGGCAAGCCATATAAGACGCAATTCGAGTGGCGTCGCCACATCAACGAGGAGCACAACTTCGATAAGCGGCAATATTTGAATATGCGCCAGCTGGACAAGTATCGTTATCAGTGCACTCAGTGCAAGGACATTGTGAGTAATTCGAAGCTAAAGGGACTGCAGGATCATCACTTCAGACATCTGCCCTATAGGCTCTACTTAAAGTGCCTCGTTTGCGGCACCTGCTACAATCACAAGCCCAACATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGCGAAATGCAGCCGAAGCCTCAGAATGGCTATGACACCATCAAATATAAAGATAAGGATATGCCAGTCATGTCCGGCACGACGTCAGACTCGCCAACACCTGGCAGCAGCAGTAACAGTGCTCGCTCACTGAAACCACAGCCCGGTTTGCTGCCCATGCGACCCGCTGGCCTAAACACGCTGGAGGATAGCATCTCCTATCACAATGCTGTCGATCTGGACTTTATTACCTACTTCTGTCCCGAGTGCAATAAGAACTTTGATTCACACGCCTTCTGGCGCAAACACATTGTCGAGCAGCACAACTTCAACAGCCGGCAAGGCTTGAACTTTCGCCAGATCGACAATCATCACTATCTGTGCCTGGAGTGCTACAAGCGGGTGACAGTCACCCACACCAAGGGCGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGCCATCTTCCCTATCGCTCATTTAAGTGCTTGACCTGCAACGGCAAATTTGTGCGAAAGCAAATGTTTTTCAAGCATTTGAACCGTGACACAAATCGCTGCGACAGCGGAGATCTTAGTAACGAGGAACACATCTCCGAGCAGCCGGAGGAGAGATCTTCGTCCGCAAACGATGCATCCCAGGCCGCCTCGTATCGCTTGCTGTGTCCGCAGTGCGGTGATAACTTCAGCACCAGCACCAAATCCGTCTGGCGTAAGCATATTAACACTCAACATGGTCTGAGTAAGCTAGAGGTGCTGCACATGTCCAAGCTGGGCGACGAGCTTTATCGCTGCGTGGACTGTGATGAGCAGCTGGAAACGAAACAGCTGCGTGTGCTGCAACAGCATCGCTTCCGCCATTTGCCGTACGCCGCCTACATACGTTGCCAGCTGTGCGAGCAACAGCAGCCGGATGAACTGGGTCATGGTCCCGTTGCAGCCGGGATGCACAGCATGTGTGAGCTGCAGCAACATATGCGCGACGAGCATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTGCTCGTCGATGTGGACGATGAGGAGAGCCACCCGATAGCGGTGGCAAGCAATGAGGCATCTGATAATGGATCATATATGCCGATGCCGCTGCAAATGCTCCTCGACGGCGATGAGGATGAGGACAGCCAAACGGCGGTAGCTAACAATGAGACGTCCGACAATGGACCATATATGCCCCTGCCGCCGCATTTACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGATCAATATCTACTGAGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEADAGPKSHSYADEIMGDDAADEQETAEDDVDAGKGPEPDDDAIFDFELEPIVSIAEPEPAPRPTVRLAPPMPVAPPVRPQQHNLQSTVSSTSSSMMGGRGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRFEQRAHGASRFGPMSHGPVRDDDDGIEVMNELMDTEPTAADDVVDEQNRSFNQGKKKRINQSAGSANAGKADNDSGSGGGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYRGYTDHHELVTHLLKHHHLETLMPEEEQEQQTVSASAGDDAEDNSGIGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHCVGYEPRNSSAGGAAVGAGQSQVKSQSTPRKQIVTVANETYEIIYLDDEQSPPNNNNVNEENDFGEQMQADDDDYATSCTSTRQLPXXXXXXXXXXXXXXXXSNQNANRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEETKPAAASVAATSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDTIKYKDKDMPVMSGTTSDSPTPGSSSNSARSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPECNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGKFVRKQMFFKHLNRDTNRCDSGDLSNEEHISEQPEERSSSANDASQAASYRLLCPQCGDNFSTSTKSVWRKHINTQHGLSKLEVLHMSKLGDELYRCVDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPVAAGMHSMCELQQHMRDEHPSFVENDEQMQLLVDVDDEESHPIAVASNEASDNGSYMPMPLQMLLDGDEDEDSQTAVANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -