Basic Information

Insect: Drosophila picticornis
Gene Symbol: -
Assembly: GCA_035043845.1
Location: JAWNMR010000362.1:8505791-8509895[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.8e-05 0.0061 16.8 0.1 1 23 149 172 149 172 0.96

2 14 0.0015 0.096 13.1 2.9 2 23 221 243 217 243 0.89

3 14 0.013 0.83 10.1 0.9 1 23 359 382 359 382 0.93

4 14 0.24 15 6.2 4.5 2 23 431 453 430 454 0.95

5 14 0.0035 0.22 12.0 0.5 1 23 517 540 517 540 0.88

6 14 8.1 5e+02 1.4 0.0 2 13 559 570 558 575 0.81

7 14 0.00074 0.046 14.1 3.3 2 23 591 613 591 613 0.96

8 14 0.00085 0.052 13.9 0.1 1 23 716 739 716 739 0.95

9 14 9.6e-05 0.0059 16.9 0.2 1 23 788 811 788 811 0.94

10 14 0.0012 0.077 13.4 2.2 2 23 861 883 860 883 0.97

11 14 0.0026 0.16 12.4 1.4 1 23 970 993 970 993 0.91

12 14 0.052 3.2 8.3 2.3 1 21 1045 1065 1045 1066 0.95

13 14 1.8 1.1e+02 3.4 0.5 3 23 1106 1129 1105 1129 0.86

14 14 9.5 5.8e+02 1.2 0.5 1 20 1147 1168 1147 1171 0.61

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.8e-05	0.0061	16.8	0.1	1	23	149	172	149	172	0.96
2	14	0.0015	0.096	13.1	2.9	2	23	221	243	217	243	0.89
3	14	0.013	0.83	10.1	0.9	1	23	359	382	359	382	0.93
4	14	0.24	15	6.2	4.5	2	23	431	453	430	454	0.95
5	14	0.0035	0.22	12.0	0.5	1	23	517	540	517	540	0.88
6	14	8.1	5e+02	1.4	0.0	2	13	559	570	558	575	0.81
7	14	0.00074	0.046	14.1	3.3	2	23	591	613	591	613	0.96
8	14	0.00085	0.052	13.9	0.1	1	23	716	739	716	739	0.95
9	14	9.6e-05	0.0059	16.9	0.2	1	23	788	811	788	811	0.94
10	14	0.0012	0.077	13.4	2.2	2	23	861	883	860	883	0.97
11	14	0.0026	0.16	12.4	1.4	1	23	970	993	970	993	0.91
12	14	0.052	3.2	8.3	2.3	1	21	1045	1065	1045	1066	0.95
13	14	1.8	1.1e+02	3.4	0.5	3	23	1106	1129	1105	1129	0.86
14	14	9.5	5.8e+02	1.2	0.5	1	20	1147	1168	1147	1171	0.61

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCTGACTTTGAAGAGCCTGATGCTGGGTCAAAGAGTCACAGTTATGCAGACGAATTTATGGGCGATGATGATGCGGATGAGCAGGAgactgctgatgatgatgttgatgctgagaAAGGACCTGAGCCAGATGACGATgccatatttgattttgaactGGAGCCAATTGTTAGCATTGCGGAACCCGAACCAGCGCCGAGACCAACTGTCCGTTTGGCGCCACCAATGCCAGTTGCTCCGCACGTTCGGCCccagcagcatcagcttcagTCAACGGTTagctccacctcctcctccatgATGGGAGGTCGCGGTGGTGCTGCCGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGAGTGCCCATTAACTATGAACTGGGCGTCATCTATATATGCCCGGCTTGTGGTGCCGAGTTCCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGCCTCAACTTTGTTGCAATTGATAAGCTGTATCACCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCATAGCCGAGAGAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGACAAGACCTGATGGTGCATCTGCGCATGGTACACTGTGACGAGGTGGTTGCCATGATGCGTGCCGGTGATGCTAGTGCTGGACGCAAGACGCGAGTACGTGAGCCGCGCGTCGAGCAGCGTGCTCATGGTGCGTCTCGGTTCGGGCCGATGAGCCATGGACCGGTTCgtgacgatgatgatggtaTCGAGGTCAAGAATGAGCTGATGGACACGGAAGCAACGGGTGCCGATGAGGTGGTTGACGAGCAGAATCGCAGCTTCAACCAAGCAAAGAAGAAGCGTATTAATCAGTCGGCCGGCTCTGCAAATGCTGGCAAAGTCGACAACGACAGTGGCAGTGCCGGCGGCGCTTCGGATATCTGCGAAGATTACATACACTACATGTGTCCCGATTGCGGCACCGACTGCGACACGCACGCCCAGTGGAGCCAGCACATTGAATTCGTTCACGACTATGTCAGCCGGCGCGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATCAAGACACTGCGCGCACACAAATTCAGTCATTTGGCTCAGCCGGATTGGATGCGTTGCAAGCTGTGCTATCGGGGTTATGCGGATCATCATGAGCTGGTAACGCACCTGCTCAAGCAGCATCATCTGGAGACTTTAATGCCCGaagaggagcaggagcagcaaacGGTCGGTGCCAGTGCCGGCGATGATGCTGAGGATAACTCTGGCATCGGCAATGGCTGCGATGATGAATCCCTCTTGCAATTTGAGGATGTACCCCGTCGTGGCGGTCGCATTGGCGGCGATGATATGTATGAGCCGCACATTGATTATCTATGCCCGCAGTGCGGCCGCGAGTTCATTGAGAAGAAGCACTGGCGCACGCATGTTGTCCAGGTGCATGGCATGAACGACCTGGCCAAGCTGAACTTTGAGGTCATCAACGATCGTCAGCTTAAATGCACAGAATGCGAGAAAATCATCACGAATGCCTACGGCATTCAGAATGCTCAGCAACACCGGATTACTCACTTGCCCTACAAGGCATATGCGCGCTGTcgcaaatgccacaaatcgTATACGGATCGCAAGGGTCTGGTTAAGCACTTGGCCACATACCATTGCGTCGGCTATGAACCGCGCAGTTCCGGTGCTGGAGGAGCGGCGGTCGGTGCAGGACAGAGCCAGGTCAAGTCGCAAACGCCgcgcaaacaaattgttaCTGTTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGAGCAATCGCCgccaaataacaataatgttaACGAGGAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGATGACTATGCCACCAGCTGCACCAGCACACGACAGTTGCCaccagctactgctgctgccactacCTCTGCGTCCAATCAAAATGCGAATCGTTATAAATGCGTTGATTGTGGCTCCTTGTTTGCCACGCAGGCGGCGCTCAAGACGCACATCAGCGAGGAGCACGATTTTATGGACACACAGTATAGCGCTAAAAAGTTTGATAATGCCGAACACGCAGAGGAGACGACACCAGCTGCAGCGTCCGTGGCGGCCACTTCGCCTCCCAAAATCTTTTCTGGCGGCTCGACAATCGAacagaattatatatatttgtgcccCTCCTGCGGCAAGCCATACAAGACGCAATTCGAGTGGCGTCGCCACATCAACGAGGAGCACAACTTTGATAAGCggcaatatttgaatatgcgCCAGCTGGACAAGTATCGTTATCAGTGCACTCAGTGCAAGGACATTGTGAGCAATTCGAAGCTAAAGGGACTGCAGGATCATCACTTCAGGCATTTGCCGTATAGGCTCTACTTAAAGTGCCTCGTTTGCGGCACCTGCTACAATCACAAGCCCAACATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGTGAAATGCAGCCGAAGCCTCAGAACGGCTATGATCCCATCAAATACAAAGATAAGGATATGCCAGTCATGTCCGGCATGACTTCAGACTCGCCGAcgcctggcagcagcagtaacagtgGTCGCTCACTGAAACCGCAGCCCGGCTTGCTGCCCATGCGACCCGCTGGCCTAAACACACTGGAGGACAGCATCTCCTATCACAATGCCGTCGATCTGGACTTTATTACCTACTTCTGTCCCGAGTGCAATAAGAACTTTGATTCGCATGCCTTCTGGCGCAAACACATTGTCGAGCAGCACAACTTCAACAGCCGGCAAGGCTTGAACTTTCGTCAGATCGACAATCATCACTATCTGTGCCTGGAGTGCTACAAGCGGGTGACAGTCACCCACACCAAGGGCGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGACATCTTCCTTATCGCTCATTTAAGTGCTTGACCTGCAACGGCAAATTTGTGcgaaagcaaatgtttttcaagCATTTGAATCGTGACACAAATCGCTGCGACAGCGGAGATCATACCAACGAGGAACACATCTCCGAGCAGCCCGATGAGAGATCTTCGTCCGCAAACGAGGCATCTGATGCAGCCTCGTATCGCTTACTGTGCCCGCAGTGTGGCGATAACttcagcaccagcaccaaaTCCATCTGGCGTAAGCATATTAACACTCAGCATGGTCTGAGCAAGCTGGAGGTGCTGCACATGTCCAAGCTGGGCGACGAGCTCTATCGCTGCGTGGACTGCAATGAGCAGCTGGAAACGAAACAGCTGCgtgtgctgcagcagcatcgttTCCGCCATTTGCCCTATGCTGCCTATATACGTTGCCAGCTGtgtgagcaacagcagccggatGAACTGGGCCATGGTCCCGTTGCAGCCGGGATGCACAGCATGTGCGAGCTGCAGCAACACATGCGCGACGAGCATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTGCTCGTCGATGTGGACGATGAAGAGAGCCACCCGATGGCGGTGGCAAGCAATGAGGTATCTGACAATGGGTCATATATGCCGATGCCGCTGCAAATGCTCCTCGACggcgatgaggatgaggacaGCCAAACGGCGGCAGCAAACAATGAGACGTCCGACAATGGGCCATATATGCCCCTGCCGCCGCATTTACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGATCAATATCTACTAAGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEPDAGSKSHSYADEFMGDDDADEQETADDDVDAEKGPEPDDDAIFDFELEPIVSIAEPEPAPRPTVRLAPPMPVAPHVRPQQHQLQSTVSSTSSSMMGGRGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRVEQRAHGASRFGPMSHGPVRDDDDGIEVKNELMDTEATGADEVVDEQNRSFNQAKKKRINQSAGSANAGKVDNDSGSAGGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYRGYADHHELVTHLLKQHHLETLMPEEEQEQQTVGASAGDDAEDNSGIGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHCVGYEPRSSGAGGAAVGAGQSQVKSQTPRKQIVTVANETYEIIYLDDEQSPPNNNNVNEENDFGEQMQADDDDYATSCTSTRQLPPATAAATTSASNQNANRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEETTPAAASVAATSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDPIKYKDKDMPVMSGMTSDSPTPGSSSNSGRSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPECNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGKFVRKQMFFKHLNRDTNRCDSGDHTNEEHISEQPDERSSSANEASDAASYRLLCPQCGDNFSTSTKSIWRKHINTQHGLSKLEVLHMSKLGDELYRCVDCNEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPVAAGMHSMCELQQHMRDEHPSFVENDEQMQLLVDVDDEESHPMAVASNEVSDNGSYMPMPLQMLLDGDEDEDSQTAAANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -