Basic Information

Insect: Drosophila kambysellisi
Gene Symbol: -
Assembly: GCA_035042185.1
Location: JAWNLS010000802.1:661850-665954[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00017 0.012 16.1 0.2 1 23 149 172 149 172 0.96

2 15 0.0015 0.11 13.1 2.9 2 23 221 243 217 243 0.89

3 15 0.013 0.93 10.1 0.9 1 23 359 382 359 382 0.93

4 15 0.79 55 4.6 5.3 2 23 431 453 430 454 0.95

5 15 0.0035 0.24 12.0 0.5 1 23 517 540 517 540 0.88

6 15 2.1 1.5e+02 3.2 0.1 2 14 559 571 558 583 0.85

7 15 0.00074 0.052 14.1 3.3 2 23 591 613 591 613 0.96

8 15 0.00085 0.059 13.9 0.1 1 23 718 741 718 741 0.95

9 15 9.5e-05 0.0067 16.9 0.2 1 23 789 812 789 812 0.94

10 15 0.0012 0.087 13.4 2.2 2 23 862 884 861 884 0.97

11 15 0.0046 0.32 11.6 2.1 1 23 971 994 971 994 0.91

12 15 0.13 9.4 7.0 2.2 1 21 1046 1066 1046 1067 0.95

13 15 0.17 12 6.6 1.5 3 23 1106 1129 1105 1129 0.96

14 15 1.6 1.2e+02 3.6 0.6 1 20 1147 1168 1147 1171 0.62

15 15 8.6 6e+02 1.3 0.2 14 23 1204 1214 1202 1214 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00017	0.012	16.1	0.2	1	23	149	172	149	172	0.96
2	15	0.0015	0.11	13.1	2.9	2	23	221	243	217	243	0.89
3	15	0.013	0.93	10.1	0.9	1	23	359	382	359	382	0.93
4	15	0.79	55	4.6	5.3	2	23	431	453	430	454	0.95
5	15	0.0035	0.24	12.0	0.5	1	23	517	540	517	540	0.88
6	15	2.1	1.5e+02	3.2	0.1	2	14	559	571	558	583	0.85
7	15	0.00074	0.052	14.1	3.3	2	23	591	613	591	613	0.96
8	15	0.00085	0.059	13.9	0.1	1	23	718	741	718	741	0.95
9	15	9.5e-05	0.0067	16.9	0.2	1	23	789	812	789	812	0.94
10	15	0.0012	0.087	13.4	2.2	2	23	862	884	861	884	0.97
11	15	0.0046	0.32	11.6	2.1	1	23	971	994	971	994	0.91
12	15	0.13	9.4	7.0	2.2	1	21	1046	1066	1046	1067	0.95
13	15	0.17	12	6.6	1.5	3	23	1106	1129	1105	1129	0.96
14	15	1.6	1.2e+02	3.6	0.6	1	20	1147	1168	1147	1171	0.62
15	15	8.6	6e+02	1.3	0.2	14	23	1204	1214	1202	1214	0.88

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGACCGACTTTGAAGAGGCTGATGATGGGACAAAAAGTCACAGTTATGCAGACGAATTTATGGGCGATGAGGATGCGGATGAGCAGGAgactgctgatgatgatgttgaggCAGGGAAAGGACCTGAGCCAGATGACGATgctatatttgattttgaacTGGAGCCAATTGTTAGCATTGCGGAACCCGAACCAGCGCCGAGACTAACTGTCCGATTGGCGCCACCAATGCCGGTTGCTCCACCCGTTCGGCcccagcagcatcatcatcagtcaACGGTTAGCTCCACATCCTCCTCCCTTATGGGAGGTCGCGGTGGTGCTGGCGCGCCACCCACAAGACCTACAACATCGCAAATAAATGCCACAGATGAGAACGGAGTGCCAATTAACTATGAACTGGGCGTCATCTATATATGCCCCGCTTGTGGTAACGAGTTCCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGCGGCCTCAACTTTGTTGGAATTGATAAGCTGTATCATCGGTGTCTGGAGTGCAACAAGCGAATTGCCATGCACAGTCGAGAGAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAACGCGAGTACAAGTACAGACAGGACCTGATGGTGCATCTACGAATGGTACACTGTGATGAGGTGGTTGCCATGATGCGTGCCGGTGATGCCAGTGCTGGACGCAAGACGCGAGTCCGTGAGCCGCGCGTTGAGCAGCGTGCTCATGGTGCGTCTCGGTTCGGGCCGATGGGCCATGGACCGGATCGTGACGATGATGATGGTATCGAGGTTAAGAATGAGCTGATGGACACGGAAGCAACGGCTGCCGATGACGTGGATGACGATCAGAATCGCAGCTTCAACCAAGCAAAGAAAAAGCGTATTAATCAGCTGGCCAGCTCTGTAAACGCTGGCAAATCCGACAACGGCAGTGGCGTCGGCGGCGGCGCTTCGGATATATGCGAAGATTACATACACTACATGTGTCCCGATTGCGGCACCGACTGCGATACGCACGCTCAATGGAGCCAGCACATTGAATTTGTACACGACTATGTCAGCCGGCGGGGACTCAATTTCCGATGCGTAGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATTCCAAACACAATCAAGACACTGCGCGCACACAAATTCAGTCATTTGGCACAGCCGGATTGGATGCGTTGCAAGCTGTGCTATAAGGGCTATACGGATCATCATGAGGTGGTCACGCATCTGCTCAAGCAGCATCATCTGGAGACATTAATGCCCGaagaggagcaggagcaacaaaCGGTCAGTGGCAATGCCGGCGATGACGGTGAGGATAACTCTGGCATGGGCAATGGCTGCGATGATGAATCCCTGTTGCAATTTGAGGATTTGCCCCGTCGTGGCGGTCGCATTGGCGGCGATGATATGTATGAGCCGCACATTGATTATCTGTGCCCGCAGTGCGGTCGCGAGTTCATTGAGAAGAAGCACTGGCGGACGCATGTCGTCCAGGTGCACGGCATGAACGATCTGGCCAAGCTGAACTTTGAGGTCATCAACGATCGTCAGCTGAAGTGCACAGAATGCGACAAGATCATCACGAATGCCTACGGCATTCAGAATGCCCAGCAACACCGGATTACTCATTTGCCCTACAAGGCATTTGCGCGTTGTcgcaaatgccacaaatcgTATACGGATCGCAAGGGTCTGGTTAAGCACTTGGCCACATACCATTGCGTTGGCTATGAACCGCGCAATTCCGGTGCAGGAGGAGCGGGAGCCGGAGCAGGACAGAGCCAGGTCAAGTCGCAAACGCCGCGCAAGCAAATTGTGACTGTTGCCAATGAAACGTATGAGATTATATATTTGGATGACGAGCAATCACCgccaaataacaataatattaatgaggAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGATGACTATGCCACAGCCGGCAGCAGCACACGCCAGTTGCAACCAGCTGGCGGGGCTACTGCTGCCACAACCTCTGCATCCAATCAAAATGCGAATCGTTATAAATGCGTTGATTGCGGCTCCCTGTTTGCTACGCAGGCAGCGCTCAAGACGCACATTAGCGAGGAGCATGATTTTATGGACACGCAGTACAGCGCTAAAAAGTTTGATAATGCCGAACACGCAGAGGAGACGGCGCCAGGAGCGTCTGTGGCAGCCACTTCACCACCCAAAATCTTTTCTGGCGGCTCGACAATCGAacagaattatatatatctttgcCCCTCCTGCGGCAAGCCATACAAGACGCAATTCGAGTGGCGTCGCCACATCAACGAGGAGCACAACTTTGATAAGCgacaatatttgaatatgcgCCAGCTGGACAAGTATCGCTATCAGTGCACCCAGTGCAAGGACATTGTGAGCAATTCGAAGCTAAAGGGTCTGCAGGATCATCACTTCAGACATTTGCCCTATAGGCTCTACTTAAAGTGCCTCGTTTGCGGCACTTGTTACAATCACAAGCCCAATATTGCCGCCCATCTGCGAACGCGCCACAACATCTTTGAGCGTGACATGCCCTGGCGTGAAACGCAGCCAAAGCCCCAAAATGGCTATGACACCATCAAATATAAAGATAAGGACATGCAAGTCATGTCCAGCTCGACGTCAGACTCACCCAcgccaggcagcagcagcaatagtgGTCGCTCACTGAAACCGCAGCCTGGTTTGCTGCCTATGCGACCCGCTGGTCTTAACACACTGGAGGATAGCATCTCCTATCACAATGCTGTCGATCTGGACTTTATTACCTACTTCTGTCCTAAGTGCAACAAGAACTTTGATTCGCACGCCTtctggcgcaaacacattgTCGAGCAGCACAACTTCAACAGCCGGCAGGGCTTGAACTTTCGCCAGATCGACAATCATCACTATCTGTGTCTGGAGTGCTACAAGCGGGTGACAGTCACCCACACCAAGGGCGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGACATCTTCCCTATCGCTCGTTTAAGTGCTTAACCTGCAGCGGTAAATTTGTGCgaaagcaaatgttttttaagcATTTGAATCGTGACACGAATCGTTGCGACAGCGGAGATCATAATAACGAGGAACCCATCGCCGAGCAGCCGGAGAGATCTTCTTCGGCAAACGATGCAGCTGATGCCGCCTCGTATCGCTTGCTGTGTCCGCAATGCGGTGATAACttcagcaccagcaccaaaTCCCTCTGGCATAAGCATATAAACACTCAACATGGTTTGAGCAAGCTGGAGGTGCTGCACATGTTCAAGCTGGGCGACGACCTCTATCGGTGCACGGACTGCGATGAGCAGCTGGAAACGAAACAGCTGCGAGTGTTGCAACAGCATCGCTTCCGCCATTTGCCCTATGCCGCCTACATACGTTGTCAGCTGTgcgaacaacagcagccggatGAACTGGGTCATGGTCCCGTTGCAGCCGGCATGCACAGCATGAGTGAGCTGCAGCAACACATGCGCGACGAGCATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTATTAATCGATATCGATGAGGACAGCCAGCCGATGGCGATGGCAAGCAACGAGTCATCCGACAATGGATCATATTTGCCGATCCCGGTGCAAATGCTAATCAATGGTGATGAGGATGAAGACAGCCAAACGGCAGCAGCTAACAATGAGGCGTCCGAAGATGGACCATATATGCCCCTGCCGCCGCATTTACTGGAGGAGGACGCTGACGGCATGGAGTTCGAAGATCAATATCTACTGAGCTAA
Protein Sequence: MEGMDLWTSMFSTDFEEADDGTKSHSYADEFMGDEDADEQETADDDVEAGKGPEPDDDAIFDFELEPIVSIAEPEPAPRLTVRLAPPMPVAPPVRPQQHHHQSTVSSTSSSLMGGRGGAGAPPTRPTTSQINATDENGVPINYELGVIYICPACGNEFRQQDMWKRHMNQMHQYNTRRGLNFVGIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRVEQRAHGASRFGPMGHGPDRDDDDGIEVKNELMDTEATAADDVDDDQNRSFNQAKKKRINQLASSVNAGKSDNGSGVGGGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYKGYTDHHEVVTHLLKQHHLETLMPEEEQEQQTVSGNAGDDGEDNSGMGNGCDDESLLQFEDLPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAFARCRKCHKSYTDRKGLVKHLATYHCVGYEPRNSGAGGAGAGAGQSQVKSQTPRKQIVTVANETYEIIYLDDEQSPPNNNNINEENDFGEQMQADDDDYATAGSSTRQLQPAGGATAATTSASNQNANRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEETAPGASVAATSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDMPWRETQPKPQNGYDTIKYKDKDMQVMSSSTSDSPTPGSSSNSGRSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPKCNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGKFVRKQMFFKHLNRDTNRCDSGDHNNEEPIAEQPERSSSANDAADAASYRLLCPQCGDNFSTSTKSLWHKHINTQHGLSKLEVLHMFKLGDDLYRCTDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPVAAGMHSMSELQQHMRDEHPSFVENDEQMQLLIDIDEDSQPMAMASNESSDNGSYLPIPVQMLINGDEDEDSQTAAANNEASEDGPYMPLPPHLLEEDADGMEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -