Doch005357.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ochracea
Gene Symbol
-
Assembly
GCA_035044125.1
Location
JAWNML010000034.1:2291138-2295160[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 9.8e-05 0.0062 16.8 0.1 1 23 149 172 149 172 0.96
2 13 0.0015 0.097 13.1 2.9 2 23 221 243 217 243 0.89
3 13 0.013 0.84 10.1 0.9 1 23 359 382 359 382 0.93
4 13 0.16 10 6.7 5.5 2 23 431 453 430 454 0.95
5 13 0.0035 0.22 12.0 0.5 1 23 515 538 515 538 0.88
6 13 8.1 5.1e+02 1.4 0.0 2 13 557 568 556 573 0.81
7 13 0.00074 0.047 14.1 3.3 2 23 589 611 589 611 0.96
8 13 0.00085 0.053 13.9 0.1 1 23 721 744 721 744 0.95
9 13 3.8e-05 0.0024 18.1 0.2 1 23 793 816 793 816 0.93
10 13 0.0012 0.078 13.4 2.2 2 23 866 888 865 888 0.97
11 13 0.0026 0.16 12.4 1.4 1 23 975 998 975 998 0.91
12 13 0.052 3.3 8.3 2.3 1 21 1050 1070 1050 1071 0.95
13 13 0.033 2.1 8.9 0.6 3 23 1111 1134 1110 1134 0.96

Sequence Information

Coding Sequence
ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCTGACTTTGAAGAGGCTGATGCTGGGCCAAAGAGTCACAGTTATGCAGACGAGTTTATGGGCGATGATGATGCGGATGAGCAGGAgactgctgatgatgatgttgatgctggGAAAGGACCTGAGCCAGATGACGATgccatatttgattttgaactGGAGCCAATTGTTAGCATTGCGGAACCCGAACCAGCGCCAAGACCAACTGTCCGATTGGCGCCACCAATGCCAGTTGCTCCGCCCGTTCGTCCCCAGCAGCATAATCTTCAGTCAACGGTTAGCTCCACCTCTTCCTCCATGATGGGAGGTCGCGGTGGTGCTGCCGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGAGTGCCCATTAACTATGAACTGGGCGTCATCTATATATGCCCAGCTTGTGGTGCCGAGTTCCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGCCTCAACTTTGTTGGAATTGATAAGCTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCACAGCCGTGAGAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAACGCGAGTACAAGTACAGACAGGACCTGATGGTGCATCTGCGCATGGTACACTGTGACGAGGTGGTTGCCATGATGCGTGCCGGTGACGCCAGTGCTGGACGCAAAACGCGAGTCCGTGAGCCGCGCGTCGAGCAGCGTGCTCATGGTGCGTCTCGGTTCGGGCCGATGAGCCATGGACCGGTTCGTGACGATGATGACGGTATCGAGGTCAAGAATGAGCTGATGGACACGGACGCAACGGCTGCCGATGATGTGGTTGACGAACAGAATCGCAGCTTCAACCAAGCAAAGAAGAAGCGTATTAATCAGTCGGCCAGCTCTGCAAACGCTGGCAAAGCCGACAACgacagtggcagtggcggCGGCGCTTCGGATATCTGCGAAGATTACATACACTACATGTGTCCCGATTGCGGCACCGACTGCGACACGCACGCCCAGTGGAGCCAGCACATTGAATTCGTGCACGACTATGTCAGCCGGCGGGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATCAAGACACTACGCGCACACAAATTCAGCCATTTGGCTCAGCCGGATTGGATGCGTTGTAAGCTGTGCTATCGGGGTTATACGGATCATCATGAGCTGGTCACGCACCTGCTCAAGCAGCATCATCTGGAGACATTAATGCCCGaagaggagcaggagcagcaaacGGTTAGTGCCGGAGATGATGCTGAGGATAACTCTGGCATCGGCAATGGCTGTGATGATGAATCCCTATTGCAATTTGAGGATGTGCCCCGTCGTGGCGGTCGTATTGGCGGCGATGATATGTATGAGCCGCATATTGATTATCTGTGCCCGCAGTGCGGCCGCGAGTTCATTGAGAAGAAGCACTGGCGCACGCATGTTGTCCAAGTGCATGGCATGAACGATCTGGCCAAGCTGAACTTTGAGGTCATCAACGATCGTCAGCTGAAATGCACAGAATGTGAGAAGATCATCACGAATGCCTACGGCATTCAGAATGCTCAGCAACACCGGATTACTCATTTGCCCTACAAGGCATATGCGCGCTGTcgcaaatgccacaaatcgTATACGGATCGCAAGGGTCTGGTTAAACACTTGGCCACATACCATTGCGTTGGTTATGAACCGCGCAATTCCGGTGCTGGAGAAGCGGCTGTCGGTGCAGGACAGAGCCAGGTCAAGTCGCAGTCAACGCCgcgcaaacaaattgttacTGTTGCCAATGAAACGTATgagattatttatttggatgACGAGCAATCACCgccaaataacaataatgttaATGAGGAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGATGACTATGCCACCAGTTGCACCAGCACACGCCAGTTGCCACCAGctaatgcagctgctgctgcggctgctgctgccactacCTCTGCGTCCAATCAAAATGCGAATCGTTATAAATGCGTTGATTGCGGGTCCCTGTTTGCCACGCAGGCGGCGCTCAAGACGCACATTAGCGAGGAGCATGATTTTATGGACACACAGTATAGCGCTAAAAAGTTTGATAATGCCGAACATGCAGAGGAGATGACGCCAGCGGCAGCTTCTGTGGCGGCCACTTCGCCTCCCAAAATCTTTTCTGGCGGCTCGACAATCGaacagaattatatatatttgtgcccCTCCTGCGGCAAGCCATATAAGACGCAATACGAGTGGCGTCGCCACATCAACGGGGAGCACAACTTCGATAAGCGgcaatatttgaatatgcGCCAGCTGGACAAGTATCGTTATCAGTGCACTCAGTGCAAGGACATTGTGAGCAATTCGAAGCTAAAGGGACTGCAGGATCATCACTTTAGACATCTGCCCTATAGGCTCTACTTAAAGTGTCTCGTTTGCGGCACCTGCTACAATCACAAGCCCAATATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGCGAAATGCAGCCGAAGCCTCAGAATGGCTATGACACCATCAAATATAAAGATAAGGACATGCCAGTCATGTCTGGCACGACGTCAGACTCGCCGACgcctagcagcagcagtaacattGCTCGCTCACTGAAACCGCAGCCCGGTTTGCTGCCCATGCGACCCGCTGGCCTAAACACACTGGAGGATAGCATCTCCTATCACAATGCTGTCGATCTAGACTTTATTACCTACTTCTGTCCCGAGTGCAATAAGAACTTTGATTCGCACGCCTTCTGGCGCAAACACATTGTCGAGCAGCACAACTTTAACAGCCGGCAAGGCTTGAACTTTCGCCAGATTGACAATCATCACTATCTGTGCCTGGAGTGCTACAAGCGGGTGACAGTCACCCACACCAAGGGCGCCATTGGGCAGCTGCAGTCACACAAGTTCCGACATCTTCCCTATCGCTCATTTAAGTGCTTGACCTGCAACGGCAAATTTGTGCGaaagcaaatgtttttcaagCATTTGAACCGTGACACAAATCGCTGCGACAGCGGAGATCATAGTAACGAGGAACACATCTCCGAGCAGGCGGAGGAGAGATCTTCGTCCGCAAACGATGCATCCGAGGCCGCCTCGTATCGCTTGCTGTGCCCGCAGTGCGGCGATAACttcagcaccagcaccaaaTCCCTCTGGCGTAAGCATATTAACACTCAACATGGTCTGAGCAAGCTGGAGGTGCTGCACATGTCCAAGCTGGGCGACGAGCTCTATTGCTGCGGGGACTGCGATGAGCAGCTGGAAACGAAACAGCTGCGTGTGCTGCAACAGCATCGCTTCCGCCATTTGCCGTACGCCGCCTACATACGTTGCCAGCTGTgcgagcaacagcagccggatGAACTAGGCCATGGTCCCGTTGCAGCCGGGATGCACAGCATGCGTGAGCTGCAGCAACACATGCGCGACGAGCATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTGCTCGTCGATGTGGACGATGAGGAGAGCCACCCGATAGCGGTGGCAAACAAAGAGGTATCTGACAATGGGTCATATATGCCGATGCCGCTGCAAATGCTCCTCGACGGCGATGAGGATGAAGACAGCCAGACGGCGGCAGCTAACAATGAGACGTCCGACAATGGACCATATATGCCCCTGCCGCCGCATTTACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGATCAATATCTACTGAGCTAA
Protein Sequence
MEGMDLWTSMFSADFEEADAGPKSHSYADEFMGDDDADEQETADDDVDAGKGPEPDDDAIFDFELEPIVSIAEPEPAPRPTVRLAPPMPVAPPVRPQQHNLQSTVSSTSSSMMGGRGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVGIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRVEQRAHGASRFGPMSHGPVRDDDDGIEVKNELMDTDATAADDVVDEQNRSFNQAKKKRINQSASSANAGKADNDSGSGGGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYRGYTDHHELVTHLLKQHHLETLMPEEEQEQQTVSAGDDAEDNSGIGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHCVGYEPRNSGAGEAAVGAGQSQVKSQSTPRKQIVTVANETYEIIYLDDEQSPPNNNNVNEENDFGEQMQADDDDYATSCTSTRQLPPANAAAAAAAAATTSASNQNANRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEEMTPAAASVAATSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQYEWRRHINGEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDTIKYKDKDMPVMSGTTSDSPTPSSSSNIARSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPECNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGKFVRKQMFFKHLNRDTNRCDSGDHSNEEHISEQAEERSSSANDASEAASYRLLCPQCGDNFSTSTKSLWRKHINTQHGLSKLEVLHMSKLGDELYCCGDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPVAAGMHSMRELQQHMRDEHPSFVENDEQMQLLVDVDDEESHPIAVANKEVSDNGSYMPMPLQMLLDGDEDEDSQTAAANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00517225;
90% Identity
iTF_00577291;
80% Identity
-