Basic Information

Insect: Drosophila incognita
Gene Symbol: -
Assembly: GCA_035042225.1
Location: JAWNLQ010000719.1:5383903-5387979[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0001 0.0068 16.9 0.1 1 23 149 172 149 172 0.96

2 14 0.0026 0.17 12.4 3.4 2 23 221 243 217 243 0.89

3 14 0.014 0.93 10.1 0.9 1 23 357 380 357 380 0.93

4 14 0.32 21 5.9 5.2 2 23 429 451 428 452 0.95

5 14 0.0037 0.24 12.0 0.5 1 23 515 538 515 538 0.88

6 14 2.3 1.5e+02 3.2 0.1 2 14 557 569 556 581 0.85

7 14 0.00079 0.052 14.1 3.3 2 23 589 611 589 611 0.96

8 14 0.0009 0.059 13.9 0.1 1 23 716 739 716 739 0.95

9 14 0.0001 0.0067 16.9 0.2 1 23 788 811 788 811 0.94

10 14 0.0013 0.087 13.4 2.2 2 23 861 883 860 883 0.97

11 14 0.0049 0.32 11.6 2.1 1 23 970 993 970 993 0.91

12 14 0.14 9.4 7.0 2.2 1 21 1045 1065 1045 1066 0.95

13 14 0.036 2.3 8.9 0.6 3 23 1105 1128 1104 1128 0.96

14 14 1.8 1.1e+02 3.6 0.6 1 20 1146 1167 1146 1170 0.62

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0001	0.0068	16.9	0.1	1	23	149	172	149	172	0.96
2	14	0.0026	0.17	12.4	3.4	2	23	221	243	217	243	0.89
3	14	0.014	0.93	10.1	0.9	1	23	357	380	357	380	0.93
4	14	0.32	21	5.9	5.2	2	23	429	451	428	452	0.95
5	14	0.0037	0.24	12.0	0.5	1	23	515	538	515	538	0.88
6	14	2.3	1.5e+02	3.2	0.1	2	14	557	569	556	581	0.85
7	14	0.00079	0.052	14.1	3.3	2	23	589	611	589	611	0.96
8	14	0.0009	0.059	13.9	0.1	1	23	716	739	716	739	0.95
9	14	0.0001	0.0067	16.9	0.2	1	23	788	811	788	811	0.94
10	14	0.0013	0.087	13.4	2.2	2	23	861	883	860	883	0.97
11	14	0.0049	0.32	11.6	2.1	1	23	970	993	970	993	0.91
12	14	0.14	9.4	7.0	2.2	1	21	1045	1065	1045	1066	0.95
13	14	0.036	2.3	8.9	0.6	3	23	1105	1128	1104	1128	0.96
14	14	1.8	1.1e+02	3.6	0.6	1	20	1146	1167	1146	1170	0.62

Sequence Information

Coding Sequence: ATGGAAGGGATGGACCTGTGGACGTCCATGTTTTCGGCCGACTTTGAAGATGCTGATGCTGGGCCAAAGAGTCACAATTATGCAGACGAGTTTATGGGCGAAGAGGATGTGGATGAGCAGGAgactgctgatgatgatgttgaggCAGGGAAAGGATGTGAGCCAGATGACGATgccatatttgattttgaactGGAGCCAATTGTTAGCATTGCGGAACCCGAACCAGCTTCCAGACCAACTGTCCGATTGGCACCACCGATGCCGGTTGCTCCGCCCGTTCGACcccagcagcatcatcatcagtcaACGGTTagctccacctcctcctccctGATGGGAGGTCGCGGTGGTGCTGCAGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGGGTGCCCATTAACTATGAACTGGGCGTCATCTATATATGCCCCGCTTGTGGTGCCGAGTTCCGCCAACAGGACATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGCCTCAACTTTGTTGGAATTGATAAGCTGTATCATCGGTGTCTGGAGTGCAACAAGCGGATTGCGATGCACAGTCGGGAGAATCTGCTGAAGCACAAGTTCACCCATTTGCCATATCGTTGCACTAAGTGCTACATCTGCAAGCGCCAGTACAAGTACAGACAAGACCTGATGGTGCATCTGCGTATGGTACACTGTGACGAAGTGGTTGCCATGATGCGTGCCGGTGATGCTAGTGCTGGACGCAAGACTCGAGTCCGGGAGCCGCGCGTCGAGCAGCGTACTCATGGTGCATCTCGGTTCGGGCCTATGGGCCATGGACCGGCTCGTGACGATGATGATGGTATCGAGCTCAAGAATGAGCTGATGGTGACGGAAGCAACGGCTGCCGAAGACGTGGATGACGATCAGAATCGCAGCTTCAACCAAACAAAGAAGAAGCGTGTTAATCAGCTGGCCGGCTCTACAAACGCTGGCAAAGCCGACAacggcagtggcagtggcgcTTCGGATATCTGCGAAGATTACATACACTACATGTGTCCCGATTGCGGCACCGACTGCGATACCCACGCTCAGTGGAGCCAGCACATTGAATTTGTGCACGACTATGTCAGTCGGCGGGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAGTGCAAGGAGTTTGTCATCCCAAACACAATCAAGACACTGCGCGCACACAAATTCAGTCATTTGGCTCAGCCGGATTGGATGCGTTGCAAGCTGTGCTACCAGGGTTATACGGATCATCATGAGCTGGTCACGCATCTGCTCAAGCAGCATCATCTGGAGACATTAATGCCCgaagaggagcaggagcagcaaacGGTTAAAGCCAGTGCCGGCGATGATGCTGAGGATAACTCTGGCAATGGAAATGGCTGCGATGATGAATCCCCGTTGCAATTTGAGGATTTGCCCCGTCGTGGCGGTCGCATTGGCGGCGATGATATGTATGAGCCGCACATTGATTATCTGTGCCCACAGTGCGGCCGCGAGTTCATCGAGAAGAAGCACTGGCGCACTCATGTCGTCCAGGTGCATGGCATGAACGATCTGGCCAAGCTGAACTTTGAAGTCATCAACGATCGTCAGCTGAAGTGCACAGAATGCGACAAGATCATTACGAATGCCTACGGCATTCAGAATGCCCAGCAACACCGAATTACTCATTTGCCCTACAAGGCATATGCGCGCTGtcgcaaatgccacaaatcaTATACGGATCGTAAGGGTCTGGTTAAGCACTTGGCCACATACCATTGCGTCGGCTATGAACCGCGCAATTCCGGTACTGGAGGAGCGGGAGCCGGAGCGGGACAGAGCCAGGTCAAGTCGCAAACGCCGCGCAAGCAAATTGTGACAGTTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGAGCAATCACCgccaaataacaataatattaatgaggAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGATGACTATGCCACAGGCTATACCAGCACACGCCAGTTGCCACcagctgcggcggctgctgctgccactacCTCTGCAtccaatcaaaatgcaaatcgtTATAAATGCGTTGATTGCGGCTCCCTTTTTGCAACGCAGGCGGCGCTCAAGACGCACATTAGCGAGGAGCATGATTTCATGGACACACAGTACAGTGCTAAAAAGTTTGATAATGCAGAACACGCAGAGGAGacggcaccagcagcagcgtctgtGGCAGCCACTTCACCTCCCAAAATCTTTTCTGGCGGCTCGACAATCGAACAGAATTATATATACCTGTGCCCCTCCTGCGGCAAGCCATACAAGACTCAATTCGAGTGGCGTCGCCACATCAACGAGGAGCACAACTTTGATAAGCgacaatatttgaatatgcgCCAGTTGGACAAGTATCGCTATCAGTGCACCCAATGCAAGGACATTGTAAGCAATTCAAAGCTAAAGGGACTGCAGGATCATCATTTCAGACATTTGCCCTATAGGCTCTACTTAAAGTGCCTCGTTTGCGGCACCTGCTACAATCACAAGCCCAACATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGTGAAATGCAGCCAAAGCCCCAGAATGGCTATGACACCATCAAATATAAAGATAACGACATGCCAGTCACGTCCGGCTCGACGTCAGACTCACCCAcgcctggcagcagcagcaacagtggtcGCTCACTGAAACCGCAGCCTGGATTGCTGCCCATGCGACCCGCTGGCCTAAACACACTGGAGGATAGCATCTCCTATCACAATGCTGTTGATCTGGACTTTATTACCTACTTCTGTCCCAAGTGCAATAAGAACTTTGATTCGCACGCGTTCTGGCGCAAGCACATTGTCGAGCAGCACAACTTCAATAGCCGGCAGGGGTTGAATTTTCGCCAGATCGACAATCATCACTATCTATGCCTGGAGTGCTACAAGAGGGTGACAGTCACCCACACCAAGGGCGCCATTGGGCAGCTGCAGTCGCACAAATTCCGACATCTTCCCTATCGCTCGTTTAAATGCTTGACCTGCAGCGGAAAATTTGTGCgaaagcaaatgtttttcaaGCATTTGAATCGTGACACGAATCGCTGCGACAGCGGAGATCATAATAATGAGGAACAAATCGCCGAGCAGCCGGAGAGATCTTCGTCTGCAAACGATGCAGCTGATGCCGCCTCGTATCGCTTGCTGTGTCCGCAGTGCGGGGATAACTTCAGTACCAGCACCAAATCCCTCTGGCGTAAGCATATTAACACTCAACATGGTCTGAGCAAGCTGGAGGTGCTGCACATGTGCAAGCTGGGCGACGAGCTCTATCGCTGCACGGACTGCGATGAGCAGCTGGAAACGAAACAGCTGCGTGTGCTGCAACAGCATCGCTTCCGCCATTTGCCATACGCCGCCTACATACGTTGCCAGCTGtgcgaacaacagcagccggatGAACTGGGTCATGGTCCCGCTGCAGCCGGCATGCACTGCATGAGTGAGCTGCAGCAACACATGCGCGACGAGCATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTATTCATCGATGTGGATGAGGACAGCCAGCCGATTGGGGTGGCAAGCAACGAGGCTTCCGACAATGGGTCATTTATGCCGATGCCGCTGCAAATGCTCCTCGATggcgatgaggatgaggacaGCCAAACGGCGGCAGCTAACAATGAGACGTCTGACAATGGACCATATATGCCCCTGCCACCACATTTACTCGAGGAGGACGTAGACGACTTGGAGTTCGAAGATCAATATCTATTGAGCTAA
Protein Sequence: MEGMDLWTSMFSADFEDADAGPKSHNYADEFMGEEDVDEQETADDDVEAGKGCEPDDDAIFDFELEPIVSIAEPEPASRPTVRLAPPMPVAPPVRPQQHHHQSTVSSTSSSLMGGRGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVGIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKRQYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRVEQRTHGASRFGPMGHGPARDDDDGIELKNELMVTEATAAEDVDDDQNRSFNQTKKKRVNQLAGSTNAGKADNGSGSGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYQGYTDHHELVTHLLKQHHLETLMPEEEQEQQTVKASAGDDAEDNSGNGNGCDDESPLQFEDLPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHCVGYEPRNSGTGGAGAGAGQSQVKSQTPRKQIVTVANETYEIIYLDDEQSPPNNNNINEENDFGEQMQADDDDYATGYTSTRQLPPAAAAAAATTSASNQNANRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEETAPAAASVAATSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDTIKYKDNDMPVTSGSTSDSPTPGSSSNSGRSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPKCNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGKFVRKQMFFKHLNRDTNRCDSGDHNNEEQIAEQPERSSSANDAADAASYRLLCPQCGDNFSTSTKSLWRKHINTQHGLSKLEVLHMCKLGDELYRCTDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPAAAGMHCMSELQQHMRDEHPSFVENDEQMQLFIDVDEDSQPIGVASNEASDNGSFMPMPLQMLLDGDEDEDSQTAAANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -