Basic Information

Insect: Drosophila cognata
Gene Symbol: -
Assembly: GCA_035041535.1
Location: JAWNLC010000232.1:456359-460444[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0001 0.0066 16.8 0.1 1 23 149 172 149 172 0.96

2 15 0.0016 0.1 13.1 2.9 2 23 221 243 217 243 0.89

3 15 0.014 0.89 10.1 0.9 1 23 359 382 359 382 0.93

4 15 0.31 20 5.9 5.2 2 23 431 453 430 454 0.95

5 15 0.0037 0.23 12.0 0.5 1 23 517 540 517 540 0.88

6 15 2.3 1.4e+02 3.2 0.1 2 14 559 571 558 583 0.85

7 15 0.00078 0.05 14.1 3.3 2 23 591 613 591 613 0.96

8 15 0.00089 0.057 13.9 0.1 1 23 718 741 718 741 0.95

9 15 0.0001 0.0064 16.9 0.2 1 23 790 813 790 813 0.94

10 15 0.0013 0.083 13.4 2.2 2 23 863 885 862 885 0.97

11 15 0.0049 0.31 11.6 2.1 1 23 972 995 972 995 0.91

12 15 0.14 9 7.0 2.2 1 21 1047 1067 1047 1068 0.95

13 15 0.035 2.2 8.9 0.6 3 23 1107 1130 1106 1130 0.96

14 15 1.7 1.1e+02 3.6 0.6 1 20 1148 1169 1148 1172 0.62

15 15 9.1 5.8e+02 1.3 0.2 14 23 1205 1215 1203 1215 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0001	0.0066	16.8	0.1	1	23	149	172	149	172	0.96
2	15	0.0016	0.1	13.1	2.9	2	23	221	243	217	243	0.89
3	15	0.014	0.89	10.1	0.9	1	23	359	382	359	382	0.93
4	15	0.31	20	5.9	5.2	2	23	431	453	430	454	0.95
5	15	0.0037	0.23	12.0	0.5	1	23	517	540	517	540	0.88
6	15	2.3	1.4e+02	3.2	0.1	2	14	559	571	558	583	0.85
7	15	0.00078	0.05	14.1	3.3	2	23	591	613	591	613	0.96
8	15	0.00089	0.057	13.9	0.1	1	23	718	741	718	741	0.95
9	15	0.0001	0.0064	16.9	0.2	1	23	790	813	790	813	0.94
10	15	0.0013	0.083	13.4	2.2	2	23	863	885	862	885	0.97
11	15	0.0049	0.31	11.6	2.1	1	23	972	995	972	995	0.91
12	15	0.14	9	7.0	2.2	1	21	1047	1067	1047	1068	0.95
13	15	0.035	2.2	8.9	0.6	3	23	1107	1130	1106	1130	0.96
14	15	1.7	1.1e+02	3.6	0.6	1	20	1148	1169	1148	1172	0.62
15	15	9.1	5.8e+02	1.3	0.2	14	23	1205	1215	1203	1215	0.88

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCCGACTTTGAAGATGCTGATGCTGGGCCAAAGAGTCACAGTTATGCAGACGAGTTTATGGGCGATGAGGATGCGGATGAGCAGGAgactgctgatgatgatgttgaggCAGGGAAGGGACGTGAGCCAGATGACGATgccatatttgattttgaactGGAGCCCATTGTTAGCATTGCGGAACCAGAACCAGCGTCCAGACCAACTGTCCGTTTGGCTCCACCGATGCCGGTTGCTCCGCCCGTTCGGCcccagcagcatcatcatcagtcaACGGTTTcttccacctcctcctccatGATGGGAGGTCGCGGTGGTGCTGCAGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGGGTACCCATTAACTATGAACTGGGCGTCATCTATATATGCCCCGCTTGTGGTGCCGAGTTCCGCCAACAAGACATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGCCTCAACTTTGTTGGAATTGATAAGCTGTATCATCGGTGTCTGGAGTGCAACAAGCGGATTGCAATGCACAGTCGGGAGAATCTGCTGAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGACAAGACCTGATGGTGCATCTACGTATGGTACACTGTGACGAAGTAGTTGCCATGATGCGTGCCGGTGATGCCAGTGCTGGACGCAAGACGCGAGTCCGGGAGCCGCGCGTCGAGCAGCGTGCTCATGGTGCGTCTCGGTTCGGTCCTATGGGCCATGGACCGGTTCGTGAGGATGATGATGGTATTGAGGTCAAGAATGAGCTGATGGTGACGGAAGCAACGGCTGCCGAAGACGTGGATGACGATCAGAATCGCAGCTTCAACCAAGCAAAGAAGAAGCGTGTTAATCAGCTGGCCGGCTCAGCAAACGCTGGCAAAGCCGACAacggcagtggcagtggcagcggcgcTTCGGATATCTGCGAAGATTACATACACTACATGTGTCCCGATTGCGGCACCGACTGCGATACCCACGCTCAGTGGAGCCAGCACATTGAATTTGTGCACGACTATGTCAGTCGGCGGGGACTCAATTTTCGTTGCGTGGATATGCAGATGCAGTGCCTCGAGTGCAAGGAGTTTGTCATACCAAACACAATCAAGACACTGCGCGCACACAAATTCAGTCATTTGGCTCAGCCGGATTGGATGCGTTGCAAGCTATGCTACCAGGGCTATACGGATCATCATGAGCTGGTCACGCATCTGCTCAAGCAGCATCATCTGGAGACATTAATGCCCgaagaggagcaggagcagcaaacGGTTAAAGCCAGTGCCGGCGATGATGCTGAGGATAActctggcaatggcaatggctgcGATGATGAATCCCTGTTGCAATTTGAGGATGTGCCCCGTCGTGGCGGTCGCATTGGCGGCGATGATATGTATGAGCCGCACATTGATTATCTGTGCCCACAGTGCGGCCGCGAGTTCATCGAGAAGAAGCACTGGCGCACGCATGTCGTCCAGGTGCATGGCATGAACGATCTGGCCAAGCTGAACTTTGAAGTCATCAATGATCGTCAGTTGAAATGCACAGAATGCGACAAGATCATCACGAATGCCTACGGCATTCAGAATGCCCAGCAACATCGGATTACTCATTTGCCCTACAAGGCATATGCGCGCTGTCGCAAGTGCCACAAATCGTATACGGATCGCAAGGGTCTGGTTAAGCACTTGGCCACATACCATTGCGTCGGCTATGAACCGCGCAATTCCGGTgctggaggagcaggagcCGGAGCAGGACAGAGCCAGGTCAAGTCGCAAACGCCGCGCAAGCAAATTGTGACAGTTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGAGCAATCACCgccaaataacaataatattaatgaggAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGATGACTATGCCACAGGCTACACCAGCACACGCCAGTTGCCAccagctgctgcggctgctgctgccactacCTCTGCATCCAATCAAAATGCGAATCGTTATAAATGCGTTGATTGCGGCTCCCTGTTTGCAACGCAGGCGGCGCTCAAGACGCATATTAGCGAAGAGCATGATTTTATGGACACACAGTACAGTGCTAAAAAGTTTGATAATGCAGAACACGCAGAGGAGacggcaccagcagcagcgtctgtGGCAGCCACTTCACCGCCCAAAATCTTTTCTGGCGGCTCGACAATCGAACAGAATTATATATACCTGTGCCCCTCCTGCGGCAAACCATACAAGACTCAATTCGAATGGCGTCGCCACATAAACGAGGAGCACAACTTTGATAAGCggcaatatttgaatatgcgCCAGTTGGACAAGTATCGCTATCAGTGCACCCAATGCAAGGACATTGTAAGCAATTCAAAGCTAAAGGGACTGCAGGATCATCATTTCAGACATTTGCCATATAGGCTCTACTTAAAGTGCCTCGTTTGCGGCACCTGCTACAATCACAAGCCCAACATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACTCCCTGGCGTGAAATGCAGCCAAAGCCCCAGAATGGCTATGACCCCATCAAATATAAAGATAACGACATGCCAGTCACGTCCGGCTCGACGTCAGACTCACCCAcgcctggcagcagcagcaacagtggtcGCTCACTGAAACCGCAGCCCGGTTTGCTGCCCATGCGACCCGCTGGCCTAAACACACTGGAGGATAGCATCTCCTATCACAATGCTGTTGATCTGGACTTTATTACCTACTTCTGCCCCAAGTGCAATAAGAACTTTGATTCGCACGCCTTCTGGCGCAAACACATTGTCGAGCAGCACAACTTCAATAGCCGGCAGGGCTTGAACTTTCGCCAGATCGACAATCATCACTATCTGTGCCTGGAGTGCTACAAGCGGGTGACAGTCACCCACACCAAGGGGGCCATTGGACAGCTGCAGTCGCACAAGTTCCGACATCTTCCCTACCGCTCGTTTAAGTGCTTGACCTGCAGCGGAAAATTTGTGCGaaagcaaatgtttttcaaGCATTTGAATCGTGACACGAATCGCTGCGACAGCGGAGATCATAATAACGAGGAACACATCGCCGAGCAGCCGGAGAGATCTTCGTCTGCAAACGATGCAGCTGATGCCGCCTCGTATCGCTTGCTGTGTCCGCAGTGCGGGGATAACTTCAGCACCAGCACCAAATCCCTCTGGCGTAAGCATATTAACACTCAACATGGTTTGAGCAAGCTGGAGGTGCTGCACATGTGTAAGCTGGGCGACGAACTCTATCGCTGCACGGACTGCGATGAGCAGCTGGAAACGAAACAGCTGCGTGtgctgcaacagcatcgcTTCCGCCATTTGCCCTACGCCGCATACATACGTTGCCAGCTGtgcgaacaacagcagccggatGATCTAGGTCATGGTCCCGCTGCAGCCGGCATGCACAGCATGAGTGAGCTGCAACAACACATGCGCGACGAGCATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTGTTTATCGATATGGATGAGGACAGCCAGCCGATTGGGGTGGCAAGCAACGAGGCTTCCGACAATGGGTCATATATGCCGATGCCGCTGCAAATGCTCCTCGATggcgatgaggatgaggacaGTCAAACGGCGACAGCTAACAATGAGACGTCCGACAATGGACCATATATGCCTCTGCCTCCACATTTACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGACCAATATCTACTGAGCTAA
Protein Sequence: MEGMDLWTSMFSADFEDADAGPKSHSYADEFMGDEDADEQETADDDVEAGKGREPDDDAIFDFELEPIVSIAEPEPASRPTVRLAPPMPVAPPVRPQQHHHQSTVSSTSSSMMGGRGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVGIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRVEQRAHGASRFGPMGHGPVREDDDGIEVKNELMVTEATAAEDVDDDQNRSFNQAKKKRVNQLAGSANAGKADNGSGSGSGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYQGYTDHHELVTHLLKQHHLETLMPEEEQEQQTVKASAGDDAEDNSGNGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHCVGYEPRNSGAGGAGAGAGQSQVKSQTPRKQIVTVANETYEIIYLDDEQSPPNNNNINEENDFGEQMQADDDDYATGYTSTRQLPPAAAAAAATTSASNQNANRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEETAPAAASVAATSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDPIKYKDNDMPVTSGSTSDSPTPGSSSNSGRSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPKCNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGKFVRKQMFFKHLNRDTNRCDSGDHNNEEHIAEQPERSSSANDAADAASYRLLCPQCGDNFSTSTKSLWRKHINTQHGLSKLEVLHMCKLGDELYRCTDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDDLGHGPAAAGMHSMSELQQHMRDEHPSFVENDEQMQLFIDMDEDSQPIGVASNEASDNGSYMPMPLQMLLDGDEDEDSQTATANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -