Basic Information

Insect: Drosophila kokeensis
Gene Symbol: -
Assembly: GCA_035042145.1
Location: JAWNLT010000346.1:18120940-18125031[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0001 0.0065 16.8 0.1 1 23 149 172 149 172 0.96

2 15 0.0025 0.16 12.4 3.4 2 23 221 243 217 243 0.89

3 15 0.014 0.88 10.1 0.9 1 23 359 382 359 382 0.93

4 15 0.3 20 5.9 5.2 2 23 431 453 430 454 0.95

5 15 0.0036 0.23 12.0 0.5 1 23 517 540 517 540 0.88

6 15 2.2 1.4e+02 3.2 0.1 2 14 559 571 558 583 0.85

7 15 0.00076 0.049 14.1 3.3 2 23 591 613 591 613 0.96

8 15 0.00074 0.048 14.1 0.1 1 23 718 741 718 741 0.95

9 15 9.8e-05 0.0063 16.9 0.2 1 23 790 813 790 813 0.94

10 15 0.0013 0.082 13.4 2.2 2 23 863 885 862 885 0.97

11 15 0.0047 0.31 11.6 2.1 1 23 972 995 972 995 0.91

12 15 0.14 8.8 7.0 2.2 1 21 1047 1067 1047 1068 0.95

13 15 0.028 1.8 9.1 0.5 3 23 1110 1133 1108 1133 0.96

14 15 2.8 1.8e+02 2.9 1.6 1 23 1151 1175 1151 1175 0.66

15 15 8.8 5.7e+02 1.3 0.2 14 23 1208 1218 1206 1218 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0001	0.0065	16.8	0.1	1	23	149	172	149	172	0.96
2	15	0.0025	0.16	12.4	3.4	2	23	221	243	217	243	0.89
3	15	0.014	0.88	10.1	0.9	1	23	359	382	359	382	0.93
4	15	0.3	20	5.9	5.2	2	23	431	453	430	454	0.95
5	15	0.0036	0.23	12.0	0.5	1	23	517	540	517	540	0.88
6	15	2.2	1.4e+02	3.2	0.1	2	14	559	571	558	583	0.85
7	15	0.00076	0.049	14.1	3.3	2	23	591	613	591	613	0.96
8	15	0.00074	0.048	14.1	0.1	1	23	718	741	718	741	0.95
9	15	9.8e-05	0.0063	16.9	0.2	1	23	790	813	790	813	0.94
10	15	0.0013	0.082	13.4	2.2	2	23	863	885	862	885	0.97
11	15	0.0047	0.31	11.6	2.1	1	23	972	995	972	995	0.91
12	15	0.14	8.8	7.0	2.2	1	21	1047	1067	1047	1068	0.95
13	15	0.028	1.8	9.1	0.5	3	23	1110	1133	1108	1133	0.96
14	15	2.8	1.8e+02	2.9	1.6	1	23	1151	1175	1151	1175	0.66
15	15	8.8	5.7e+02	1.3	0.2	14	23	1208	1218	1206	1218	0.88

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCCGACTTTGAAGATGCTGATGCTGGGTCAAAGAGTCACAGTTATGCAGACGAGTTTATGGGCGAAGAGGATGCGGATGAGCAGGAgactgctgatgatgatgttgaggCAGGGAAGGGACGTGAGCCAGATGACGATGccatatttgattttgaattggAGCCAATTGTTAGCATTGCGGAACCCGAACCAGCTGCAAGACTAACTGTCCGATTGGCACCACCGATGCCTGTTGCTCCGCCCGTTCGCccccagcagcatcagcatcagtcaACTGTTAGCTCCACCTCCTCTTCCCTGATGGGAGGTCGCGGTGGTGCTGCAGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGGGTGCCCATTAACTATGAACTGGGCGTCATCTATATATGCCCCGCTTGTGGTGCCGAGTTCCGCCAACAGGACATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGCCTGAACTTTGTTGGAATTGATAAGCTGTATCATCGGTGTCTGGAGTGCAACAAGCGGATTGCGATGCACAGTCGGGAGAATCTGCTGAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAGCGCCAGTATAAGTACAGACAAGACCTGATGGTGCATCTGCGTATGGTACACTGTGACGAAGTGGTTGCCATGATGCGTGCCGGTGATGCCAGTGCTGGACGCAAGACGCGAGTTCGGGAGCCGCGTGTCGAGCAGCGTGCTCATGGTGTATCTCGGTTCGGGCCAATGGGCCATGGACCGGTTCGTGAGGATGATGATGGTATCAAGGTCAAGAATGAGCTGATGGTGACGGAAGCAACGGCTGCCGAAGACGTGGATGACGATCAGAATCGCAGCTTCAACCAAGCAAAGAAGAAGCGTGTTAATCAGCTGGCTGGCTCTGCAAACGCTGGCAAAGCCGACAacggcagtggcagtggcagcggcgcTTCGGATATCTGCGAAGATTATATACACTACATGTGTCCCGATTGCGGCACCGACTGCGATACCCACGCTCAGTGGAGCCAGCACATTGAATTTGTGCACGACTATGTCAGTAGGCGGGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAGTGCAAGGAGTTTGTAATCCCAAACACAATCAAGACACTGCGCGCACACAAATTCAGTCATTTGGCTCAGCCGGATTGGATGCGTTGCAAGCTGTGCTACCAGGGTTATACGGATCATCATGAGCTGGTCACGCATCTGCTCAAGCAGCATCATCTGGAGACATTAATGCCCgaagaggagcaggagcagcaaacGGTTAAAGCCAGTGACGGCGATGATGCAGAGGACAActctggcaatggcaatggctgcGATGATGAATCCCTGTTGCAATTTGAGGATGTGCCCCGTCGTGGCGGTCGCATTGGCGGCGATGATATGTATGAGCCGCACATTGATTATCTGTGCCCACAGTGTGGCCGCGAGTTCATCGAGAAGAAGCACTGGCGCACTCATGTTGTCCAGGTGCATGGCATGAACGATCTGGCTAAGCTGAACTTTGCAGTCATCAACGATCGTCAGCTGAAGTGCACAGAATGCGACAAGATCATTACGAATGCCTACGGCATTCAGAATGCCCAGCAACACAGGATTACTCATTTGCCCTACAAGGCATATGCTCGCTGTCGCAAGTGCCACAAATCGTATACGGATCGCAAGGGTCTGGTTAAGCACTTGGCCACATACCATTGCGTCGGCTATGAACTGAGCAATTCCGGTGCTGGAGGAGCGGGAGCCGGAGCAGGACAGAGCCAGGTCAAGTCGCTAACGCCACGCAAGCAAATTGTAATAGTTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGAGCAATCACCGCCAaatagcaataatattaatgaggAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGACGACTATGCAACAGGCTATGCCAGCACACGCCAGTTGCCACAAGCTgccgcggctgctgctgccactccCTCTGCAACCAATCAAAATGCGAATCGTTATAAATGCGTTGATTGTGGCTCCCTGTTTGCAACGCAGGAGGCGCTCAAGACACACATTAGCGAGGAGCATGATTTCATGGACACACAGTACAGTGCTAAAACGTTTGATAATGCAGAACACGCAGAGGAGACcgtaccagcagcagcgtctgtGGCAGCCACTTCACCGCCCAAAATCTTTTCTGGTGGCTCGACAATCGAACAGAATTATATATACCTGTGCCCCTCCTGCGGCAAGCCATACAAGACTCAATTCGAGTGGCGTCGCCACATCAACGAGGAGCACAACTTTGATAAGCGgcaatatttgaatatgcGCCAGTTGGACAAGTATCGTTATCAGTGCACCCAATGCAAGGACATTGTAAGCAATTCAAAGCTAAAGGGACTGCAGGATCATCATTTCAGACATTTGCCCTATAGGCTCTACTTAAAGTGCCTCGTTTGCGGTACCTGCTATAATCACAAGCCCAATATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGTGAAATGCAGCCAAAGCCTCAGAATGGCTATGACACCATCAAATATAAAGATAACGACATGCCAGTCACGTCCGGCTCGACGTCAGACTCACCCAcgcctggcagcagcagcaacagtggtCGCTCACTGAAACCGCAGCCCGGTTTGCTGCCAATGCGACCCGCTGGCCTAAACACACTGGAGGATAGCATCTCCTATCACAATGCCGTTGATCTGGACTTTATTACCTACTTTTGCCCAAAGTGCAATAAGAACTTTGATTCGCACGCTTTCTGGCGCAAGCACATTGTCGAGCAGCACAACTTCAATAGCCGGCAAGGGTTGAATTTTCGCCAGATCGACAATCATCACTATCTGTGCCTGGAGTGCTACAAGAGGGTGACAGTCACCCACACCAAGGGCGCCATTGGGCAACTGCAGTCGCACAAGTTCCGACATCTTCCCTATCGCTCATTTAAGTGCTTGACCTGCAGCGGAAAATTTGTGCgaaagcaaatgtttttcaagCATTTGAATCGTGACACGAATCGCTGTGACAGCGGAGATCATAATAACGAGGAACACATCGCCGAGCAGCCGGAGAGATCTTCGTCTGCAAACGATGCACCTGATGCAGCTGATGCCGCCTCGTATTGCTTGCTGTGTCCGCAGTGCGGGGATAACttcagcaccagcaccaaATCCCTCTGGCGTAAGCATATTAACACTCAACATGGTCTGAGCAAGCTGGAGGTGTTGCACATGTGCAAGCTGGGCGACGAGGTCTATCGCTGCACGGACTGCGATGAGCAGCTGGAAACGAAACAGCTGCGTGTGCTGCAACATCATCGCTTCCGCCATTTGCCATACGCCGCATACATACGTTGCCAGCTGTgcgaacaacagcagccggatGAACTGGGTCATGGTCCCGCTGCAGCCGGCATGCACAGCATGAGTGAGCTGCAGCAACACATGCGCGACGAGCATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTATTCATCGATATGGATGAGGACAGCCAGCCGATTGGGGTGGCAAGCAACGAGGCTTCCGACAATGGGTCATATATGCCGATGCCGCTGCAAATGCTCTTCCATggcgatgaggatgaggacaGCCAAACGGCGGCAGCTAACAATGAGACGTCCGACAATGGACCATATATGCCCCTGCCGCCACATTTACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGATCAATATCTATTGAGTTAA
Protein Sequence: MEGMDLWTSMFSADFEDADAGSKSHSYADEFMGEEDADEQETADDDVEAGKGREPDDDAIFDFELEPIVSIAEPEPAARLTVRLAPPMPVAPPVRPQQHQHQSTVSSTSSSLMGGRGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVGIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKRQYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRVEQRAHGVSRFGPMGHGPVREDDDGIKVKNELMVTEATAAEDVDDDQNRSFNQAKKKRVNQLAGSANAGKADNGSGSGSGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYQGYTDHHELVTHLLKQHHLETLMPEEEQEQQTVKASDGDDAEDNSGNGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFAVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHCVGYELSNSGAGGAGAGAGQSQVKSLTPRKQIVIVANETYEIIYLDDEQSPPNSNNINEENDFGEQMQADDDDYATGYASTRQLPQAAAAAAATPSATNQNANRYKCVDCGSLFATQEALKTHISEEHDFMDTQYSAKTFDNAEHAEETVPAAASVAATSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDTIKYKDNDMPVTSGSTSDSPTPGSSSNSGRSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPKCNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGKFVRKQMFFKHLNRDTNRCDSGDHNNEEHIAEQPERSSSANDAPDAADAASYCLLCPQCGDNFSTSTKSLWRKHINTQHGLSKLEVLHMCKLGDEVYRCTDCDEQLETKQLRVLQHHRFRHLPYAAYIRCQLCEQQQPDELGHGPAAAGMHSMSELQQHMRDEHPSFVENDEQMQLFIDMDEDSQPIGVASNEASDNGSYMPMPLQMLFHGDEDEDSQTAAANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -