Basic Information

Insect: Drosophila heteroneura
Gene Symbol: -
Assembly: GCA_035042245.1
Location: JAWNLO010000845.1:346263-350373[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.7e-05 0.0061 16.8 0.1 1 23 149 172 149 172 0.96

2 14 0.0015 0.097 13.1 2.9 2 23 221 243 217 243 0.89

3 14 0.013 0.83 10.1 0.9 1 23 365 388 365 388 0.93

4 14 0.066 4.2 7.9 4.5 2 23 437 459 436 460 0.95

5 14 0.0034 0.22 12.0 0.5 1 23 523 546 523 546 0.88

6 14 7.9 5e+02 1.4 0.0 2 13 565 576 564 581 0.81

7 14 0.00073 0.046 14.1 3.3 2 23 597 619 597 619 0.96

8 14 0.00083 0.053 13.9 0.1 1 23 725 748 725 748 0.95

9 14 9.4e-05 0.006 16.9 0.2 1 23 797 820 797 820 0.94

10 14 0.0012 0.078 13.4 2.2 2 23 870 892 869 892 0.97

11 14 0.0026 0.16 12.4 1.4 1 23 979 1002 979 1002 0.91

12 14 0.051 3.2 8.3 2.3 1 21 1054 1074 1054 1075 0.95

13 14 0.033 2.1 8.9 0.6 3 23 1115 1138 1114 1138 0.96

14 14 6.3 4e+02 1.7 0.4 1 20 1156 1177 1156 1180 0.61

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.7e-05	0.0061	16.8	0.1	1	23	149	172	149	172	0.96
2	14	0.0015	0.097	13.1	2.9	2	23	221	243	217	243	0.89
3	14	0.013	0.83	10.1	0.9	1	23	365	388	365	388	0.93
4	14	0.066	4.2	7.9	4.5	2	23	437	459	436	460	0.95
5	14	0.0034	0.22	12.0	0.5	1	23	523	546	523	546	0.88
6	14	7.9	5e+02	1.4	0.0	2	13	565	576	564	581	0.81
7	14	0.00073	0.046	14.1	3.3	2	23	597	619	597	619	0.96
8	14	0.00083	0.053	13.9	0.1	1	23	725	748	725	748	0.95
9	14	9.4e-05	0.006	16.9	0.2	1	23	797	820	797	820	0.94
10	14	0.0012	0.078	13.4	2.2	2	23	870	892	869	892	0.97
11	14	0.0026	0.16	12.4	1.4	1	23	979	1002	979	1002	0.91
12	14	0.051	3.2	8.3	2.3	1	21	1054	1074	1054	1075	0.95
13	14	0.033	2.1	8.9	0.6	3	23	1115	1138	1114	1138	0.96
14	14	6.3	4e+02	1.7	0.4	1	20	1156	1177	1156	1180	0.61

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCTGACTTTGAAGAGGCTGATGCTGGGCCAAAGAGTCACAGTTATGCAGACGAGTTTATGGGCGATGAGGATGCGGATGAGCAGGAgacagctgatgatgatgttgatgctggGAAAGGACCTGAGCCAGATGACGATGccatatttgattttgaactGGAGCCAATTGTAAGCATGGCGGAACCCGAACCAGCACCCAGACCAACTGTCCGATTGGCGCCACCAATGCCGGTTGCTCCGCCCGTTCGGCCCCAGCAGCATCATCTTCAGTCAACGGTTagctccacctcctcctccatgATGGGAGGTCGCGGTGGTGCTGCCGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGAGTGCCCATTAACTATGAACTGGGCGTCATCTACATATGCCCGGCTTGTGGTGCCGAGTTCCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGCCTCAACTTTGTTGCAATTGATAAACTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCACAGCCGGGAGAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAACGCGAGTACAAGTACAGACAAGACCTGATGGTGCATCTGCGCATGGTACACTGTGACGAGGTGGTTGCCATGATGCGTGCCGGTGATGCCAGTGCTGGACGCAAGACGCGAGTCCGTGAGCCGCGCTTCGAGCAGCGTGCTCATGGTGCGTCTCGGTTCAGGCCGATCAGCCATGGACCGGTTCgtgacgatgatgatggtaTCGAGGTCAAGAATGAGCTGATGGACACGGAAGCAGCGGCTGCGACGGCTGCGACGGCTGCCGATGACGTCGATGACGAGCAGAATCGCAGCTTCAACCAAGCAAAGAAGAAGCGTATTAATCAGTCGGCCGGCTCTGCAAACGCTGGCAAAGCCGACAACGACAGTGGCAGTGGCGGCGGCGCTTCGGATATCTGCGAAGATTACATACACTACATGTGTCCCGATTGCGGCACCGACTGCGACACGCACGCTCAGTGGAGCCAGCACATTGAATTCGTGCACGACTATGTCAGCCGGCGGGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATCAAGACACTGCGCGCACACAAATTCAGTCATTTGGCTCAGCCAGATTGGATGCGTTGCAAGCTGTGCTATCGGGGTTATACGGATCATCATGAGCTGGTCGCGCACCTGCTCAAGCAGCATCATTTGGAGACATTAATGCCCgaagaggagcaggagcagcaaacGGTCAGTGCCAGTGCCGGCGATGATGCTGAGGATAACTCTGGCATCGGCAATGGCTGCGATGATGAATCCCTGTTGCAATTTGAGGATGTGCCCCGTCGTGGCGGCCGCATTGGCGGCGATGATATGTATGAGCCGCACATTGATTATCTGTGCCCGCAGTGCGGACGCGAGTTCATTGAGAAGAAGCACTGGCGCACGCATGTTGTCCAGGTGCATGGCATGAACGATCTGGCCAAGCTGAACTTTGAGGTCATCAACGATCGTCAGCTGAAATGCACAGAATGCGAGAAGATCATCACGAATGCCTACGGCATTCAGAATGCTCAACAACACCGGATTACTCATTTGCCCTACAAGGCATATGCGCGCTGTcgcaaatgccacaaatcgTATACGGATCGCAAGGGTCTGGTTAAGCACTTGGCCACATACCATTCCGTCGGCTATGAACCGCGCAATTCCGGTGCTGGAGGAGCGGCAGTCGGTGCAGGACAGAGCCAGGTCAAGTCACAAACGCCgcgcaaacaaattgttactGTTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGAGCAATCCCCgccaaataacaataatattaatgaggAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGATGACTATGCCACAGGCTGCACCAGCACACGCCAGTTGCCAccagctgctgcggctgctgctgctgccacaaccTCTGCGTCCAATCAAAATGCGAATCGTTATAAATGCGTTGATTGTGGCTCCCTGTTTGCCACGCAGGCGGCGCTCAAGACGCACATTAGCGAGGAGCACGATTTTATGGACACGCAGTATAGCGCTAAAAAGTTTGATAATGCCGAACACGCAGAGGAGACGACGCCAGCGGCAGCGTCCGTGGCGACCACTTCGCCTCCCAAAATCTTTTCTGGCGGCTCGACAATCGAacagaattatatatatttgtgcccCTCCTGCGGCAAGCCATATAAGACGCAATTCGAATGGCGTCGCCACATCAACGAGGAGCACAATTTTGATAAGCggcaatatttgaatatgcgCCAGTTGGACAAGTATCGTTATCAGTGCACTCAGTGCAAGGATATTGTGAGCAATTCGAAGCTAAAGGGACTGCAGGATCATCACTTCAGACACTTGCCCTATAGGCTCTACTTAAAGTGCCTAGTTTGCGGCACCTGCTACAATCACAAGCCCAACATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGTGAAATGCAGCCGAAGCCTCAGAATGGCTATGACACCATCAAATATAAAGATAAGGATATGCCAGCCATGTCCGGTACGACGTCAGACTCGCCGACgcctggcagcagcagtaacagtacTCGCTCACTGAAACCGCAGCCCGGTTTGCTGCCCATGCGACCCGCTGGCCTAAACACACTGGAGGATAGCATCTCCTATCACAATGCTGTCGATCTGGACTTTATTACCTACTTCTGCCCCGAGTGCAATAAGAACTTTGATTCGCACGCTTTCTGGCGCAAACACATTGTCGAGCAGCACAACTTCAACAGCCGGCAAGGCTTGAACTTTCGCCAGATCGACAATCATCACTATCTGTGCCTGGAGTGCTATAAGCGGGTGACAGTTACCCATACCAAGGGCGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGACATCTTCCCTATCGCTCATTTAAGTGCTTGACCTGCAACGGCAAATTTGTGCGaaagcaaatgtttttcaaGCATTTGAACCGTGACACAAATCGCTGCGACAGTGGAGATCATAGTAACGAGGAACACATCTCCGAGCAGCCGGAGGAGAGATCTTCGTCCGCAAACGATGCATCCGATGCCGCCTCGTATCGCTTGCTGTGCCCGCAGTGCGGAGATAACTTCAGCACCAGCACCAAATCCCTCTGGCGTAAGCATATTAACACTCAACATGGTCTGAGCAAGCTGGAGGTGCTGCACATGTCCAAGCTGGGCGACGAGCTCTATCGCTGCGTGGACTGCGATGAGCAGCTGGAAACGAAACAGCTGCGTGTGCTGCAACAGCATCGCTTCCGCCATTTGCCCTATGCCGCCTACATACGTTGCCAGCTCtgcgagcaacagcagccggatGAACTGGGTCATGGTCCCGTTGCAGCCGGGATGCACAGCATGTGTGAGCTGCAGCAACACATGCGCGACGAACATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTGCTCGTCGATGTGGACGATGAGGAGAGTCACCCGATGGCGGTGGCAAGCAATGAGGCATCTGACAATGGGTCATATATGCCGATGCCGCTGCAAATGCTCCTCGacggcgatgacgatgaggacaGCCAAACGGCGGCAGCTAACAATGAGACGTCCGACAATGGACCATATATGCCCCTGCCGCCGCATTTACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGATCAATATCTACTGAGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEADAGPKSHSYADEFMGDEDADEQETADDDVDAGKGPEPDDDAIFDFELEPIVSMAEPEPAPRPTVRLAPPMPVAPPVRPQQHHLQSTVSSTSSSMMGGRGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRFEQRAHGASRFRPISHGPVRDDDDGIEVKNELMDTEAAAATAATAADDVDDEQNRSFNQAKKKRINQSAGSANAGKADNDSGSGGGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYRGYTDHHELVAHLLKQHHLETLMPEEEQEQQTVSASAGDDAEDNSGIGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHSVGYEPRNSGAGGAAVGAGQSQVKSQTPRKQIVTVANETYEIIYLDDEQSPPNNNNINEENDFGEQMQADDDDYATGCTSTRQLPPAAAAAAAATTSASNQNANRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEETTPAAASVATTSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDTIKYKDKDMPAMSGTTSDSPTPGSSSNSTRSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPECNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGKFVRKQMFFKHLNRDTNRCDSGDHSNEEHISEQPEERSSSANDASDAASYRLLCPQCGDNFSTSTKSLWRKHINTQHGLSKLEVLHMSKLGDELYRCVDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPVAAGMHSMCELQQHMRDEHPSFVENDEQMQLLVDVDDEESHPMAVASNEASDNGSYMPMPLQMLLDGDDDEDSQTAAANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -