Basic Information

Insect: Drosophila melanosoma
Gene Symbol: -
Assembly: GCA_035042045.1
Location: JAWNLY010000178.1:6954316-6958380[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00024 0.017 15.5 0.2 1 23 147 170 147 170 0.96

2 15 0.0014 0.097 13.1 2.9 2 23 219 241 215 241 0.89

3 15 0.012 0.84 10.1 0.9 1 23 351 374 351 374 0.93

4 15 0.034 2.3 8.7 3.7 2 23 423 444 422 445 0.95

5 15 0.0032 0.22 12.0 0.5 1 23 509 532 509 532 0.88

6 15 2 1.4e+02 3.2 0.1 2 14 551 563 550 575 0.85

7 15 0.0015 0.1 13.0 1.5 2 21 583 602 583 603 0.93

8 15 0.00011 0.0074 16.6 0.1 1 23 708 731 708 731 0.96

9 15 8.8e-05 0.006 16.9 0.2 1 23 780 803 780 803 0.94

10 15 0.0011 0.078 13.4 2.2 2 23 853 875 852 875 0.97

11 15 0.0031 0.21 12.0 1.7 1 23 962 985 962 985 0.91

12 15 0.12 8.4 7.0 2.2 1 21 1037 1057 1037 1058 0.95

13 15 0.013 0.92 10.0 0.5 2 23 1096 1120 1095 1120 0.95

14 15 6.5 4.5e+02 1.6 1.5 3 23 1140 1162 1138 1162 0.87

15 15 7.9 5.4e+02 1.3 0.2 14 23 1195 1205 1193 1205 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00024	0.017	15.5	0.2	1	23	147	170	147	170	0.96
2	15	0.0014	0.097	13.1	2.9	2	23	219	241	215	241	0.89
3	15	0.012	0.84	10.1	0.9	1	23	351	374	351	374	0.93
4	15	0.034	2.3	8.7	3.7	2	23	423	444	422	445	0.95
5	15	0.0032	0.22	12.0	0.5	1	23	509	532	509	532	0.88
6	15	2	1.4e+02	3.2	0.1	2	14	551	563	550	575	0.85
7	15	0.0015	0.1	13.0	1.5	2	21	583	602	583	603	0.93
8	15	0.00011	0.0074	16.6	0.1	1	23	708	731	708	731	0.96
9	15	8.8e-05	0.006	16.9	0.2	1	23	780	803	780	803	0.94
10	15	0.0011	0.078	13.4	2.2	2	23	853	875	852	875	0.97
11	15	0.0031	0.21	12.0	1.7	1	23	962	985	962	985	0.91
12	15	0.12	8.4	7.0	2.2	1	21	1037	1057	1037	1058	0.95
13	15	0.013	0.92	10.0	0.5	2	23	1096	1120	1095	1120	0.95
14	15	6.5	4.5e+02	1.6	1.5	3	23	1140	1162	1138	1162	0.87
15	15	7.9	5.4e+02	1.3	0.2	14	23	1195	1205	1193	1205	0.88

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCAGACTTTGAAGAGGCTGATGCTGGGCCAAAGAATCATAGTTATGCAAACGATTTTATGGGCGATGAGGATGCGGATGAACTGGATACTGCTGAAGATAATGTTGAGGCAAGGAAAGGACCTGAACCAGATGACGATGccatatttgattttgaactGGAGCCAATTGTTAGCATTGCGGAACCCGAAACAGCGTCCAGAGCAACTGTACGATTGGCGCCACCAATGCCGGTTGCTCCGCCTGTTCGACCCCAGCAGCACCCGTCAACGGTTAgctccacctcctcctccctGATGGTAGGTCGCGGTGGTGCTGCCGCGCCACCTACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGAGTACCCATTAACTATGAACTGGGTGTCATCTATATATGCCCTGCTTGTGGGTCCGAGTTCCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACCCGCCGTGGCCTCAACTTTGTTGGAATTGATAAGCTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCACAGTCGGGAAAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGACAGGATCTGATGGTGCATCTGCGCATGGTACACTGTGAAGATGTGGTTGTCATGATGCGTGCAGGTGATGCAAGTGCTGGACGCAAGACCCGAGTCCGTGAGCCGCGCGTCGAGCAGCGTGCTCATGGTGCGTCTCGTGTCGGGACGATTGGCCGTGGTCCGCTtcgtgatgatgatgatagtATCGAGGTCAAGAATAAGCTGATGGACACGGAGGCAACGGCTGCCGACGACGTGGATGACGATCAGAATCGCAGCTTCAGCCAAGGAAAGAAGAAGCGTGTTAATCAGCTGTCCGACAACGGCGgtgccagtggcagtggcggCAGCGCTTCGGATATCTGCGAAGATTACATACACTATATGTGTCCCGATTGTGGCACTGACTGCGACACGCACGCTCAATGGAGCCAACACATTGAATTTGTGCACGACTATGTCAGCCGGCGCGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCGAACACAATTAAAACACTGCGCGCACACAAATTCAGTCATTTGGCTCAACCGGATTGGATGCGTTGCAAGCTATGCTACCGAGGCTATACGGATCATAATGAGCTGGTCACGCATCTGCTCAAACACCATCATCTGGACACATTAATGCCCgaagaggagcaggagcagcaaacGGTAATTGCAAATGTCGGCGATGATGCTGAGGATAACTCTGGCATTGGCAATGGCTGCGATGATGAATCCCTCTTGCAATTTGAGGATGTGCCCCGTCGTGGCGGTCGCATTGGCGGCGATGATATTTATGAGCCGCATATTGATTATCTGTGCCCGCAGTGCGGCCGCGAGTTCATTGAGAAGAAGCACTGGCGCACGCATGTCGTCCAAGTGCATGGCATGAACATTCTGGCCAAGCTAAACTTTGAGGTCATCAATGACCGGCAGCTGAAGTGCACAGAATGCGACAAGATCATCACTAATGCCTACGGCATTCAGAATGCCCAACAACATCGGATTACTCATTTGCCCTACAAGGCATATGCACGCTGccgcaaatgccacaaatcgTATACGGATCGCAAAGGTCTGGTTAAGCATTTGGCCACATACCGTTGCGCCGGCAATGAGCCGCGCAATTCCGGTGCTGGAGGAGCAGGAGATGGTGCAGAAAAGAACCAGGTCAAGTCGCAAACGCCGCGAAAGCAAATTGTGACTATTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGACCAATCACCgccaaataacaataatgttaATGAGGAAAATGATTTTGGTGAGCAGATGCAAGCGGATGAAGATGACTATGCCACAGGCTGCACCAGCACACGGCAGTTGCCACCAGCTGCCGCGGCTGCCACTACCTCTGCATCCAATCAAAATGCGAATCGCTATAAATGCGTTGATTGCGGCTCCTTGTTTACCACGCAGGCGGCGCTCAAGGCGCACATTAACGAGGAGCATGATTTTATGGACACACAGTATAGCGCTAAAAAGTTTGATAAGACCGAACACGCAGACGAGACAGCGCCAGTAGCATCGTCTGTGGCAGCCACTTTACCACCGAAAATCTTTTCTGGCGGCTCCACAATCGAacagaattatatatatctgtgccCCTCCTGCGGCAAGCCATACAAGACGCAATTCGAGTGGCGTCGCCACATCAACGAAGAGCACAACTTTGATAAGCGgcaatatttgaatatgcGACAGCTGGACAAGTATCGCTATCAGTGCACCCAGTGCAAGGACATTGTGAGTAACTCAAAGCTAAAGGGACTCCAGGATCATCACTTTAGACATTTGCCTTATAGGCTCTACTTAAAGTGCCTCGTTTGCGGCACCTGCTACAATCACAAGCCAAACATTGCCGCCCATCTGCGGACGCGGCACAACATCTTTGAGCGTGACACTCCCTGGCGTGAAAtgcagccaaagccaaagaatGGCTATGATACCATCAAATACAAAGATAAGGATATGCCAGTCATGTCCGCGTCTACGTCAGAATCACCCACgcctggcagcagcagcaacagtggtcGCTCACTGAAACCGCATCCTGGTTTTCTGCCCATGCGACCCGCTGGCCTAAACACACTGGAGGATAGCATCTCCTATCACAATGCAGTCGATCTGGACTTTATCACCTACTTCTGCCCCAAGTGCAACAAGAACTTTGATTCGCACGCCTTCTGGCGCAAACACATTGTCGAGGAACACAACTTTAACAGCCGGCAGGGCTTGAACTTTCGCCAGATCGACAATCATCACTATCTGTGCTTGGAGTGCTACAAGCGGGTGACAGTCACCCACACCAAGGGCGCCATTGGGCAGCTGCAATCACACAAGTTCCGACATCTTCCATATCGCTCGTTTAAGTGCTTGACCTGCAGCGGAAAATTTGTGcgaaagcaaatgtttttcaagCATTTAAATCGTGACACGAATCGCTGCGACAGCGGAGACCATAATAACGAGGAACACATCGCTGAGCAGCCGGAGAGATCTTCATCAGCAAACGATGCAGCTGATGCCGCCTCGTATCGCTTAATGTGTCCGCAGTGCGGCGATAACttcagcaccagcaccaaATCCCTCTGGCGCAAGCATATTAACACTCAGCATGGTCTAAGCAAGCTGGATGTGCTGCACATGTGCAAGCTGGGCGATGATCTCTATGGCTGCACTGACTGCGATGAGCAGCTGGAAACGAAACAGTTGCGAGAGCTGCAACACCATCGCTTCCGTCACTTACCCTATGCCGCCTACATACGTTGCCAGCTGTGCGAACGAGAACAGCAGGATGAACAGGGTCATGGTCCCGTTGCAGCCGGCATGCACAGCATGAGTGAGCTGCAGCAACATATGCGCGATGAGCATCCATCGATGGTGGGAAACGATGAGCAAATGCAGTCGTTCATCGATGCGGATGAGGACAGCCAGCCGATTGCGGTGGCAAGCACCGAGGCTCCCGACAATGGGTCATACATGCCGATGCCGTTACAAATGCACCTCGATggcgaggaggaggatgaggatgaagaCAGCCCAACGGCGGCAGCTAACAATGATATGTCGTCCGATGATGGACCATATATGACCCTGTCGCCGCATTTACTGGAGGAGGACGCAGACGACTTGGAGTTCGAAGATCAATATCTATTGAGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEADAGPKNHSYANDFMGDEDADELDTAEDNVEARKGPEPDDDAIFDFELEPIVSIAEPETASRATVRLAPPMPVAPPVRPQQHPSTVSSTSSSLMVGRGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGSEFRQQDMWKRHMNQMHQYNTRRGLNFVGIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCEDVVVMMRAGDASAGRKTRVREPRVEQRAHGASRVGTIGRGPLRDDDDSIEVKNKLMDTEATAADDVDDDQNRSFSQGKKKRVNQLSDNGGASGSGGSASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYRGYTDHNELVTHLLKHHHLDTLMPEEEQEQQTVIANVGDDAEDNSGIGNGCDDESLLQFEDVPRRGGRIGGDDIYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNILAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYRCAGNEPRNSGAGGAGDGAEKNQVKSQTPRKQIVTIANETYEIIYLDDDQSPPNNNNVNEENDFGEQMQADEDDYATGCTSTRQLPPAAAAATTSASNQNANRYKCVDCGSLFTTQAALKAHINEEHDFMDTQYSAKKFDKTEHADETAPVASSVAATLPPKIFSGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPKNGYDTIKYKDKDMPVMSASTSESPTPGSSSNSGRSLKPHPGFLPMRPAGLNTLEDSISYHNAVDLDFITYFCPKCNKNFDSHAFWRKHIVEEHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGKFVRKQMFFKHLNRDTNRCDSGDHNNEEHIAEQPERSSSANDAADAASYRLMCPQCGDNFSTSTKSLWRKHINTQHGLSKLDVLHMCKLGDDLYGCTDCDEQLETKQLRELQHHRFRHLPYAAYIRCQLCEREQQDEQGHGPVAAGMHSMSELQQHMRDEHPSMVGNDEQMQSFIDADEDSQPIAVASTEAPDNGSYMPMPLQMHLDGEEEDEDEDSPTAAANNDMSSDDGPYMTLSPHLLEEDADDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00511515; iTF_00535564; iTF_00500541;
80% Identity: -