Basic Information

Insect: Drosophila villosipedis
Gene Symbol: -
Assembly: GCA_035043025.1
Location: JAWNNF010000040.1:418457-422491[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.5e-05 0.0061 16.8 0.1 1 23 149 172 149 172 0.96

2 14 0.0015 0.096 13.1 2.9 2 23 221 243 217 243 0.89

3 14 0.013 0.8 10.2 0.9 1 23 359 382 359 382 0.93

4 14 0.16 10 6.7 5.5 2 23 431 453 430 454 0.95

5 14 0.0034 0.22 12.0 0.5 1 23 517 540 517 540 0.88

6 14 7.8 5e+02 1.4 0.0 2 13 559 570 558 575 0.81

7 14 0.00072 0.046 14.1 3.3 2 23 591 613 591 613 0.96

8 14 0.00082 0.052 13.9 0.1 1 23 725 748 725 748 0.95

9 14 3.9e-05 0.0025 18.1 0.4 1 23 797 820 797 820 0.95

10 14 0.0012 0.077 13.4 2.2 2 23 870 892 869 892 0.97

11 14 0.0025 0.16 12.4 1.4 1 23 979 1002 979 1002 0.91

12 14 0.05 3.2 8.3 2.3 1 21 1054 1074 1054 1075 0.95

13 14 0.032 2.1 8.9 0.6 3 23 1115 1138 1114 1138 0.96

14 14 6.2 4e+02 1.7 0.4 1 20 1156 1177 1156 1180 0.61

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.5e-05	0.0061	16.8	0.1	1	23	149	172	149	172	0.96
2	14	0.0015	0.096	13.1	2.9	2	23	221	243	217	243	0.89
3	14	0.013	0.8	10.2	0.9	1	23	359	382	359	382	0.93
4	14	0.16	10	6.7	5.5	2	23	431	453	430	454	0.95
5	14	0.0034	0.22	12.0	0.5	1	23	517	540	517	540	0.88
6	14	7.8	5e+02	1.4	0.0	2	13	559	570	558	575	0.81
7	14	0.00072	0.046	14.1	3.3	2	23	591	613	591	613	0.96
8	14	0.00082	0.052	13.9	0.1	1	23	725	748	725	748	0.95
9	14	3.9e-05	0.0025	18.1	0.4	1	23	797	820	797	820	0.95
10	14	0.0012	0.077	13.4	2.2	2	23	870	892	869	892	0.97
11	14	0.0025	0.16	12.4	1.4	1	23	979	1002	979	1002	0.91
12	14	0.05	3.2	8.3	2.3	1	21	1054	1074	1054	1075	0.95
13	14	0.032	2.1	8.9	0.6	3	23	1115	1138	1114	1138	0.96
14	14	6.2	4e+02	1.7	0.4	1	20	1156	1177	1156	1180	0.61

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCTGACTTTGAAGAGGCTGATGCTGGGCCAAAGAGTCACAGTTATGCAGACGAGTTTATGGGCGATGATGATGCGGATGCGCAGGAgactgctgatgatgatgttgatgctggGAAAGGACCTGAGCCAGATGACGATgccatatttgattttgaactgGAGCCAATTGTTAGCATTGCGGAACCCGAACCAGCGCCAAGACCAACTGTCCGATTGGCGCCACCAATGCCAGTTGCTCCGCCCGTTCGGCCCCAGCAGCATAATCTTCAGTCAACGGTTagctccacctcctcctccatgATGGGAGGTCGCGGTGGTGCTGCCGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGAGTGCCCATTAACTATGAACTGGGCGTCATCTATATATGCCCGGCTTGTGGTGCCGAGTTCCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGCGGCCTCAACTTTGTTGGAATTGATAAGCTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCACAGCCGGGAGAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGACAGGACCTGATGGTGCATCTGCGCATGGTACACTGTGACGAGGTGGTTGCCATGATGCGTGCCGGTGACGCCAGTGCTGGACGCAAGACGCGAGTCCGTGAGCCGCGCGTCGAGCAGCGTGCTCATGGTGCGTCTCGGTTCGGGCCGATGAGCCATGGACCGGTTCGTGACGATGATGACGGTATCGAGGTCAAGAATGAGCTGATGGACACGGAAGCAACGGCTGCTGATGATGTGGTTGACGAACAGAATCGCAGCTTCAACCAAGCAAAGAAGAAGCGTATTAATCAGTCGACTAGCTCTGGAAACGCTGGCAAAGCCGACAACgacagtggcagtggcggCGGCGCTTCGGATATCTGCGAAGATTACATACACTACATGTGTCCCGATTGCGGCACCGACTGCGACACGCACGGCCAGTGGAGCCAGCACATTGAATTCGTGCACGACTATGTCAGCCGGCGGGGACTTAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATCAAGACACTGCGCGCACACAAATTCAGTCATTTGGCTCAGCCGGATTGGATGCGTTGCAAGCTGTGCTATCGGGGTTATACGGATCATCATGAGCTGGTCACGCACCTGCTCAAGCAACATCATCTGGAGACATTAATGCCCGaagaggagcaggagcagcaaacGGTTAGTGCCAGTGCCGGCGATGATGCTGAGGATAACTCTGGCATCGGCAATGGCTGTGATGATGAATCCTTGTTGCAATTTGAGGATGTGCCCCGTCGTGGCGGTCGTATTGGCGGCGATGATATGTATGAGCCGCATATTGATTATCTGTGCCCGCAGTGCGGCCGCGAGTTTATTGAGAAGAAGCACTGGCGCACGCATGTTGTCCAGGTGCATGGCATGAACGATCTGGCCAAGCTGAACTTTGAGGTCATCAACGATCGTCAGCTGAAATGCACAGAATGCGAGAAGATCATCACGAATGCCTACGGCATTCAGAATGCTCAGCAACACCGGATTACTCATTTGCCCTACAAGGCATATGCGCGCTGtcgcaaatgccacaaatcgTATACAGATCGCAAGGGTCTGGTTAAACACTTGGCCACATACCATAGCGTTGGCTATGAACCGCGCAATTCTGGTGCTGGAGGAGCGGCTGTCGGTGCAGGACAGAACCAGGTCAAGTCTCAGTCAACGCCgcgcaaacaaattgttactGTTGCCAATGAAACGTATGAGATTATCTATTTGGATGACGAGCAATCACCgccaaataacaataatgttaATGAGGAGAATGATTTTGGCGAGCAGATGCAAgcggatgatgatgactaTGCCACCAGTTGCACCAGCACACGCCAGTTGCCACCAGctattgcagctgctgctgcggctgctgctgctgctgccactacCTCTGCGTCCAATCAAAATGCGAATCGTTATAAATGCGTTGATTGCGGCTCCCTGTTTGCCACGCAGGCGGCGCTCAAGACGCACATTAGCGAGGAGCATGATTTTATGGACACACAGTATAGCGCTAAAAAGTTTGATAATGCCGAACATGCAGAGGAGACGACGCCAGCGGCAGCTTCTGTGGCGGCCACTTCGCCTCCCAAAATCTTTTCTGGCGGCTCGACAATCGAacagaattatatatatttgtgcccCTCCTGTGGCAAGCCATATAAGACGCAATTCGAGTGGCGTCGCCACATCAACAAGGAGCACAACTTCGATAAGCGgcaatatttgaatatgcgCCAGCTGGACAAGTATCGTTATCAGTGCACTCAGTGCAAGGACGTTGTGAGCAATCCCAAGCTAAAGGGATTGCAGGATCATCACTTCAGACATCTGCCCTATAGGCTCTACTTAAAGTGCCTCGTTTGCGGCACCTGCTACAATCACAAGCCCAACATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGCGAAATGCAGCCGAAGCCTCAGAATGGCTATGACACCATCAAATATAAAGATAAGGACATGCCAGTCATGTCTGGCACGACGTCAGACTCGCCGACgcctggcagcagcagtaacagtgCTCGCTCACTGAAACCGCAGCCCGGTTTGCTGCCTATGCGACCCGTTGGCCTAAACACACTGGAGGATAGCATCTCCTATCACAATGCTGTCGATCTGGACTTTATTACCTACTTCTGTCCCGAGTGCAATAAGAACTTTGATTCGCACGCCTTCTGGCGCAAACACATTGTCGAGCAGCACAACTTCAACAGCCGGCAAGGCTTGAACTTTCGCCAGATCGACAATCATCACTATCTGTGCCTGGAGTGCTACAAGCGGGTGACAGTCACCCACACCAAGGGCGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGACATCTTCCCTATCGCTCATTTAAGTGCTTGACCTGCAACGGCAAATTTGTGCGaaagcaaatgtttttcaagCATTTGAACCGTGACACAAATCGCTGCGACAACGGAGATCATAGTAACGAGGAACACATCTCCGAGCAGGCGGAGGAGAGATCTTCGTCCGTAAACGATGCATCCGAGGCCGCCTCGTATCGCTTGCTGTGCCCGCAGTGCGGCGATAACttcagcaccagcaccaaaTCCCTCTGGCGTAAGCATATTAACACTCAACATGGTCTGAGCAAGCTGGAGGTGCTGCACATGTCCAAGCTGGGCGACGAGCTCTATCGCTGCGTGGACTGCGATGAGCAGCTGGAAACGAAACAGCTGCGTGTGCTGCAACAGCATCGCTTCCGCCATTTGCCGTATGCCGCCTACATACGTTGCCAGCTGTgcgagcaacagcagccggatGAACTGGGCCATGGTCCCGTTGCGGCCGGGATGCACAGCATGTGTGAGCTGCAGCAACACATGCGCGACGAGCATCCCTCGTTTGTGGAGAACGATGAGCAAATGCAGTTGCTCGTCGATGTGGACGATGAGGAGAGCCACCCGATAGCGGTGGCAAGCAATGAGGGATCTGACAATGGGTCATATATGCCGATGCCGCTGCAAATGCTCCTCGACGGCGATGAGGATGAAGACAGCCAGACGGCGGCAGCTAACAATGAGACGTCCGACAATGGACCATATATGCCCCTGCCGCCGCATTTACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGATCAATATCTACTGAGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEADAGPKSHSYADEFMGDDDADAQETADDDVDAGKGPEPDDDAIFDFELEPIVSIAEPEPAPRPTVRLAPPMPVAPPVRPQQHNLQSTVSSTSSSMMGGRGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVGIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDASAGRKTRVREPRVEQRAHGASRFGPMSHGPVRDDDDGIEVKNELMDTEATAADDVVDEQNRSFNQAKKKRINQSTSSGNAGKADNDSGSGGGASDICEDYIHYMCPDCGTDCDTHGQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYRGYTDHHELVTHLLKQHHLETLMPEEEQEQQTVSASAGDDAEDNSGIGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHSVGYEPRNSGAGGAAVGAGQNQVKSQSTPRKQIVTVANETYEIIYLDDEQSPPNNNNVNEENDFGEQMQADDDDYATSCTSTRQLPPAIAAAAAAAAAAATTSASNQNANRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEETTPAAASVAATSPPKIFSGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINKEHNFDKRQYLNMRQLDKYRYQCTQCKDVVSNPKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDTIKYKDKDMPVMSGTTSDSPTPGSSSNSARSLKPQPGLLPMRPVGLNTLEDSISYHNAVDLDFITYFCPECNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGKFVRKQMFFKHLNRDTNRCDNGDHSNEEHISEQAEERSSSVNDASEAASYRLLCPQCGDNFSTSTKSLWRKHINTQHGLSKLEVLHMSKLGDELYRCVDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPVAAGMHSMCELQQHMRDEHPSFVENDEQMQLLVDVDDEESHPIAVASNEGSDNGSYMPMPLQMLLDGDEDEDSQTAAANNETSDNGPYMPLPPHLLEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -