Basic Information

Insect: Drosophila sproati
Gene Symbol: -
Assembly: GCA_018904355.1
Location: JAEIFY010000056.1:5474339-5480618[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 8.4e-05 0.0056 16.8 0.1 1 23 149 172 149 172 0.96

2 14 0.0013 0.089 13.1 2.9 2 23 221 243 217 243 0.89

3 14 0.011 0.76 10.1 0.9 1 23 359 382 359 382 0.93

4 14 0.04 2.7 8.4 3.6 2 23 431 453 430 453 0.96

5 14 0.003 0.2 12.0 0.5 1 23 515 538 515 538 0.88

6 14 6.9 4.6e+02 1.4 0.0 2 13 557 568 556 573 0.81

7 14 0.00063 0.043 14.1 3.3 2 23 589 611 589 611 0.96

8 14 0.00072 0.049 13.9 0.1 1 23 726 749 726 749 0.95

9 14 8.1e-05 0.0055 16.9 0.2 1 23 798 821 798 821 0.94

10 14 0.0011 0.071 13.4 2.2 2 23 871 893 870 893 0.97

11 14 0.0022 0.15 12.4 1.4 1 23 980 1003 980 1003 0.91

12 14 0.044 3 8.3 2.3 1 21 1055 1075 1055 1076 0.95

13 14 0.028 1.9 8.9 0.6 3 23 1116 1139 1115 1139 0.96

14 14 6.1 4.1e+02 1.5 0.5 1 20 1157 1178 1157 1181 0.61

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	8.4e-05	0.0056	16.8	0.1	1	23	149	172	149	172	0.96
2	14	0.0013	0.089	13.1	2.9	2	23	221	243	217	243	0.89
3	14	0.011	0.76	10.1	0.9	1	23	359	382	359	382	0.93
4	14	0.04	2.7	8.4	3.6	2	23	431	453	430	453	0.96
5	14	0.003	0.2	12.0	0.5	1	23	515	538	515	538	0.88
6	14	6.9	4.6e+02	1.4	0.0	2	13	557	568	556	573	0.81
7	14	0.00063	0.043	14.1	3.3	2	23	589	611	589	611	0.96
8	14	0.00072	0.049	13.9	0.1	1	23	726	749	726	749	0.95
9	14	8.1e-05	0.0055	16.9	0.2	1	23	798	821	798	821	0.94
10	14	0.0011	0.071	13.4	2.2	2	23	871	893	870	893	0.97
11	14	0.0022	0.15	12.4	1.4	1	23	980	1003	980	1003	0.91
12	14	0.044	3	8.3	2.3	1	21	1055	1075	1055	1076	0.95
13	14	0.028	1.9	8.9	0.6	3	23	1116	1139	1115	1139	0.96
14	14	6.1	4.1e+02	1.5	0.5	1	20	1157	1178	1157	1181	0.61

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCTGACTTTGAAGATGCTGATGCTGGGCCAAAGAGTCACAGTTATGCAGACGAGTTTATGGGCTATGATGATGCGGATGAGCAGGAGACTGCTGATGATGATGTTGGTGCTGGGAAAGGACCTGAGCCAGATGACGATGCCATATTTGATTTTGAACTGGAGCCAATTGTTAGCATTGCGGAACCCGAACCAGCGCCAAGGCCAACTGTCCGATTGGCGCCACCAATGCCAGTTGCTCCGCCCGTTCGGTCCCAGCAGCATAATCTTCAGTCAACGGTTAGCTCCACCTCCTCCTCCATGATGGGAGGTCGCGGTGGTGCTACCGCGCCACCCACACGACCTACAACATCGCAAATCAATGCCACAGATGAGAACGGAGTGCCCATTAACTATGAACTGGGCGTCATCTATATATGCCCGGCTTGTGGTGCCGAGTTCCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACTCGCCGTGGCCTCAACTTTGTTGCAATTGATAAGCTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCACAGCCGGGAGAATCTGCTCAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGACAGGACCTGATGGTGCATCTGCGCATGGTACACTGTGACGAGGTGGTTTCCATGATGCGTGCCGGTGACGCCAGTGCTGGACGCAAGACGCGAGTCCGTGAGCCGCGCGTCGAGCAGCGTGCTCATGGTGCGTCTCGATTCGGGCCGATGAGCCATGGACCGGTTCGTGACGATGATGATGGTATCGAGGTCAAGAATGAGCTGATGGACACGGAAGTAACGGCTGCCGATGATGTGGTTGACGAACAGAATCGCAGCTTCAACCAAGCAAAGAAGAAGCGTGTTAATCAGTCGGCCAGCTCTGCAAACGCTGGCAAAGCCGACAACGACAGTGGCAGTGGCGGCGGCGCTTCGGATATCTGCGAAGATTACATACACTACATGTGTCCCGATTGCGGCACCGACTGCGACACGCACGCCCAGTGGAGCCAGCACATTGAATTCGTGCACGACTATGTCAGCCGGCGGGGACTCAATTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATTAAGACACTGCGCGCACACAAATTCAGTCATTTGGCTCAGCCGGATTGGATGCGTTGCAAGCTGTGCTATCGGGGTTATACGGATCATCATGAGCTGGTCACGCACCTGCTCAAGCAGCATCAGCTGGAGACATTAATGCCCGAAGAGGAGCAGGAGCAGCAAACGGTCAGTGCCGGCGATGATGCTGAGGATAACTCTGGCATCGGCAATGGCTGTGATGATGAATCCCTGTTGCAATTTGAGGATGTGCCCCGTCGTGGCGGTCGTATTGGCGGCGATGATATGTATGAGCCGCATATTGATTATCTGTGCCCGCAGTGCGGCCGCGAGTTCATTGAGAAGAAGCACTGGCGCACGCATGTTGTCCAGGTGCATGGCATGAACGATCTGGCCAAGCTGAACTTTGAGATCATCAACGATCGGCAGCTGAAATGCACAGAATGCGAGAAGATCATCACGAATGCCTATGGCATTCAGAATGCTCAGCAACACCGGATTACTCATTTGCCCTACAAGGCATATGCGCGCTGTCGCAAATGCCACAAATCGTATACGGATCGTAAGGGTCTGGTTAAGCACTTGGCCACATACCATTGCGTTGGCTATGAACCGCGCAATTCCGGTGCTGGAGGAGCGGCTGTCGGTGCAGGACAGAGCCAGGTCAAGTCTCAGTCAACGCCGCGCAAACAAATTGTTACTGTTGCCAATGAAACGTATGAGATTATATATTTGGATGACGAGCAATCACCGCCAAATAACAATAATGTTAATGAGGAGAATGATTTTGGCGAGCAGATGCAAGCGGATGATGATGACTATGCCACCAGTTGCACCAGCACACGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCAATCAAAATGCGAATCGTTATAAATGCGTTGATTGCGGCTCCCTGTTTGCCACGCAGGCGGCGCTCAAGACGCACATTAGCGAGGAGCATGATTTTATGGACACACAGTATAGCGCTAAAAAGTTTGATAATGCCGAACATGCAGAGGAGACGACGCCAGCGGCAGCTTCTGTGGCGGCCACTTCGCTTCCCAAAATCTTTACTGGCGGCTCGACAATCGAACAGAATTATATATATTTGTGCCCCTCCTGCGGCAAGCCATATAAGACGCAATTCGAGTGGCGTCGCCACATCAACGAGGAGCACAACTTCGATAAGCGGCAATATTTGAATATGCGCCAGCTGGACAAGTATCGTTATCAGTGCACTCAGTGCAAGGACATTGTGAGCAATTCGAAGCTAAAGGGACTGCAGGATCATCACTTTAGACATTTGCCCTATAGGCTCTACTTAAAGTGCCTCGTTTGCGGCACATGCTACAATCACAAGCCCAACATTGCCGCCCATCTGCGTACGCGCCACAACATCTTTGAGCGTGACACGCCCTGGCGCGAAATGCAGCCGAAGCCTCAGAATGGCTATGACACCATCAAATATAAAGATAAGGACATGCCAGTCATGTCTGGCACGACGTCAGACTCGCCGACGCCTGGCAGCAGCAGTAACAGTGCTCGCTCACTGAAACCGCAGCCCGGTTTGCTGCCCATGCGACCCGCTGGCCTAAACACACTGGAGGATAGCATCTCCTATCACAATGCTGTCGATCTGGACTTTATTACCTACTTCTGTCCCGAGTGCAATAAGAACTTCGATTCGCACGCCTTCTGGCGCAAACACATTGTCGAGCAGCACAACTTCAACAGTCGGCAAGGCTTGAACTTTCGCCAGATCGACAATCATCACTATCTGTGCCTGGAGTGCTACAAGCGGGTGACAGTCACCCACACCAAGGGCGCCATCGGGCAGCTGCAGTCGCACAAGTTCCGACATCTTCCCTATCGCTCATTTAAGTGCTTGACCTGCAACGGCAAATTTGTGCGAAAGCAAATGTTTTTCAAGCATTTGAACCGTGACACAAATCGCTGCGACAGCGGAGATCATAGTAACGAGGAACACATCTCCGAGCAGGCAGAGGAGAGATCTTCGTCCGCAAACGATGCATCCGAGGCCGCCTCGTATCGCTTGCTGTGCCCGCAGTGCGGCGATAACTTCAGCACCAGCACCAAATCCCTCTGGCGTAAGCATATTAACACTCAACATGGTCTGAGCAAGCTGGAGGTGCTGCACATGTCCAAGCTGGGCGACGAGCTCTATCGCTGCATGGACTGCGATGAGCAGCTGGAAACGAAACAGCTGCGTGTGCTGCAACAGCATCGCTTCCGCCATTTGCCCTATGCCGCCTACATACGTTGCCAGCTGTGCGAGCAACAGCAGCCGGATGAACTGGGCCATGGTCCCGTTGCAGCCGGGATGCACAGCATGTGTGAGCTGCAGCAACACATGCGCGACGAGCATCCCTCGTTTGTGGAGAATGATGAGCAAATGCAGTTGCTCGTCGATGTGGACGATGAGGAGAGCCACCCGATAGCGGTGGCAAGCAATGAGGCATCTGACAATGGGTCTTATATGCCGATGCCGCTGCAAATGCTCCTCGACGGCGATGAGGATGAAGACAGCCAGACGGCGGCAGCTAACAATGAGACGTCCGACAATGGACCATATATGCCCCTGCCGCCGCATATACTGGAGGAGGACGTAGACGACTTGGAGTTCGAAGATCAATATCTACTGAGCTAA
Protein Sequence: MEGMDLWTSMFSADFEDADAGPKSHSYADEFMGYDDADEQETADDDVGAGKGPEPDDDAIFDFELEPIVSIAEPEPAPRPTVRLAPPMPVAPPVRSQQHNLQSTVSSTSSSMMGGRGGATAPPTRPTTSQINATDENGVPINYELGVIYICPACGAEFRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVSMMRAGDASAGRKTRVREPRVEQRAHGASRFGPMSHGPVRDDDDGIEVKNELMDTEVTAADDVVDEQNRSFNQAKKKRVNQSASSANAGKADNDSGSGGGASDICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFSHLAQPDWMRCKLCYRGYTDHHELVTHLLKQHQLETLMPEEEQEQQTVSAGDDAEDNSGIGNGCDDESLLQFEDVPRRGGRIGGDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEIINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHCVGYEPRNSGAGGAAVGAGQSQVKSQSTPRKQIVTVANETYEIIYLDDEQSPPNNNNVNEENDFGEQMQADDDDYATSCTSTRXXXXXXXXXXXXXXXXXXXXXXXXXNQNANRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEHAEETTPAAASVAATSLPKIFTGGSTIEQNYIYLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERDTPWREMQPKPQNGYDTIKYKDKDMPVMSGTTSDSPTPGSSSNSARSLKPQPGLLPMRPAGLNTLEDSISYHNAVDLDFITYFCPECNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGKFVRKQMFFKHLNRDTNRCDSGDHSNEEHISEQAEERSSSANDASEAASYRLLCPQCGDNFSTSTKSLWRKHINTQHGLSKLEVLHMSKLGDELYRCMDCDEQLETKQLRVLQQHRFRHLPYAAYIRCQLCEQQQPDELGHGPVAAGMHSMCELQQHMRDEHPSFVENDEQMQLLVDVDDEESHPIAVASNEASDNGSYMPMPLQMLLDGDEDEDSQTAAANNETSDNGPYMPLPPHILEEDVDDLEFEDQYLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517225;
90% Identity: iTF_00577291;
80% Identity: -