Dneo010984.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila neoperkinsi
Gene Symbol
-
Assembly
GCA_037043555.1
Location
JBAMBG010006913.1:25221-30516[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.002 0.14 12.6 2.5 2 23 145 166 144 166 0.97
2 13 0.00012 0.0089 16.4 1.3 1 23 386 408 386 408 0.98
3 13 6.7 4.9e+02 1.5 0.8 1 23 414 437 414 437 0.88
4 13 8.4 6.1e+02 1.2 0.3 1 23 466 489 466 489 0.89
5 13 0.0038 0.28 11.7 2.1 5 23 788 806 785 806 0.92
6 13 0.043 3.1 8.4 1.4 1 23 812 835 812 835 0.98
7 13 6.5 4.7e+02 1.6 1.0 2 19 875 893 871 895 0.55
8 13 0.0027 0.2 12.2 0.7 1 23 915 938 915 938 0.97
9 13 0.01 0.75 10.4 0.4 1 23 1091 1114 1091 1114 0.92
10 13 0.00031 0.022 15.2 3.0 1 23 1128 1150 1128 1150 0.98
11 13 0.0014 0.1 13.1 4.0 2 23 1183 1207 1182 1207 0.90
12 13 0.082 6 7.5 0.2 1 23 1212 1234 1212 1234 0.96
13 13 0.0057 0.42 11.2 1.3 1 23 1240 1263 1240 1263 0.96

Sequence Information

Coding Sequence
ATGGCGCAAAAACGTCTAAAAGCAGCGGACATGgaaatcaattacaaatttacatgTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTCAAGCTGGACTCCCTCATCGACTGTGGCAACGATGATGCCagtgacaatgacaatgatgCATCGTCCACAACAAAATTGCCCCTGTTGCGTTTACTGCTCTTCTGCATGCGCACCGAAAATCTGCCCGAGCTGCCGCAATACATTTGCGTGGAATGCCGAAAAAGTTTACAAATTGCCTACTATTTCATCCAGAACGGTTTGCGTGCCCACGAAATATTGTGTCGCAAGCTGTGTCCGGGCAAGCTGCAAACCAAACCGCGCATCAACGGACAACATTTAGCCCTAAGGCTCGAGGCAAAAGCTGGCGCAGCGTTGCTGGACACGCACAGGGAGAAACCcctaaaatgcaaaatatgcgGTGAGGTTATCCACAATCGCTTGGAGCTGAAACATCATCTACGAATGCATtcagAGTCTCGACACAAGTGTAAATTGTGCAACTTTGTAACGCTGAAGCATCGCCAGCTGCTGGAGCACTATCGCAAATCGCATGGCTTGACAACGGCCCAAATTGAGCATCAGTTGAAAATACGAAGATCGCTGCAGGCGGCTGccaacgaTGATGGTCAGGTGAAGGTGTGTACAATGGAGGACATGGAGCTGCTGATACCCACAGTGTTGACGCCCGAGGATTTCACGCATCCACAACTAGATGCGGATCAATTGCGTGACATTGAACAGCAATTGACGAGCAGCTCGCTGGGATTGGCCAATACCACAGCTGCGTCCACGGAACCGGTGACGGCAAATGCCAGCGGAAGCAGTGCTAATATGAGCATAGGTGCAGAATTTCTGGTCATGCCCGATGGCTCGTTGCAGCAAGTGAATGATGCTGGCGTTGTCTTCGAATATATTGATGATAGTAAAAATGCGGccaacataacaacaacaacaagcacaacgaCCAATGTAACGCTGGAGAGCCTGTTGAGTGACTCGAAAACCGATTTAACCTATGATGCAATGAACATTGATCTGAGTCCTATGGTTGTCGACAATGCGCTGCCACAGATAACAGTCAAGCCCAAGGGGCGACCAGCGCCAGCGTCTACTGGTGCCCtgaaacacaaatgcaaactgTGTCCCAAAGCATTTCCGACGGTGGCACGCCTCAAATCTCACCAGCTAACGCATAGCCATTTACCTAAATTCTATTGTGATCAGTGCACATTTTATTCTCTGCGCAGCGCCGATCTCATCCAGCATTATACGAGCGAGCATAATATATGCGTTAGCGATACGAAAGCTAGTCAAGTGGAGAAGTCACCAATGCTGACGGCAATGTTAACGGATCGCAATCGCATCTTCTCCTGCGATATGTGTCTGTTTGAGACGCCGAGCGGCGGTCAGCTGCGCTTGCATTACAGTGATAAGCATCTCATTGTGCCCAGTGAGATACAGCTGCGTCCCAGCTGGATCAGAGATCAGCAGGATGGCAATGCGAAGCTGAAAAGTGGCGATGCCAAAACACAACCAGACATTCCACTGGGCATTAAATATCCAACCATGACGCAGTGTGCTGCAGCCACAATTGCAACAACGACGGCGAAAACAACAAGCATGGTGCAACAGCCGcaggcaataacaacaacaacaacggcagtgACGTCCACGGGTGGCATTAATGTTGTTGTCGATGCCAGCTCATTGTTCtatgcagcaactgctgctgaaaATGTAGGAACAACGGCTGCAATAACGACTGCAACAACgggtgcaacagcaacaacgggtgcaacagcaacaacaacaacgggcgCATCATCTACAGATTCAAGCACAATTGCAATATTTCCAGAACAATGcctggcaacaacagcaaaagcagcaataacaaatccACAAGAGGCAAGCAATCAGGCAgtgacaacatcaacaacaacaacaacaacaaatcccAATACTAGCACATTTGGTGATATGCAGGAGTTTATAGATAATACAGATGTGGCAGCTATATGCACAATACCCGCCGACGATATGCCTGTGGATGGCGATGATATCGtaatcgataataataatattagtcTGGATTTTGATGCCGAAAATCTATTTGAGGAATTTGAAGATGTCGAAGTTGGCGAAGAGgttgacgatgacgacgcTGAGGAGGatgacgaggatgaggatgaggatgatgcGGACAATGATGATGAGAATGATAACAATGATGCGGCTGCCGATCAAAATCTCTTGCTAACcagcgacgatgacgatgtggATGACTTTGACGACGAACAATCGAAGCATCTGCAGAAACCCTATTGCATCTTTTGCAACAAAAAGTTTACCAGCCAATACAAGTTCGAGAATCATATGTTTGTGCATCGCGGTTTGGCACCCTATCGCTGTGAGCTGTGCACCAATCTGTACAATATGAAACGTCTGCTCATACGACATTATAAAACGGTTCACAAAAAGATGCCCACGCGGGACATGGTGCAGGCCAAGGGCGACAAGGTAGCCGTGCCGTGTACGGCTATCgaaaagataaatataaatgcggACAAAAatCCCTTGCTGATGTGCGCCAAGTGTCCCTTTGAATGTGAGCTGGATGTGGATATGCGCAAGCATTTAAATGCCCATCATGGCATCAACGATGGCGTTTCTATGCATGCCAACGAAGTGTTTATCATACGCAAACTGCCCTATGAATGTCCACGCTGCATTCGTTCATTTGCGGCAAAGCGAACGTTGACACGCCACTTGCAGCGTAGCCATTTGGTGGATACAATCATTGAGATGCAGGCGCTTCAATTGACAACCAGTTCGGCGGCAACGACAACCacagcgacgacaacaaccacattgCCGAACAATGGCAGCGATGGCAATAAGGCCACAGCAAATGCGGTTGTGGAGTCGTCCAATAATGGCAatatcgatgtcgatgtcgatctTGGCGATGGCGGCGATGGAAAATGCGATTTTacaccaacaacacaacaGTCTGCAGTATCAACGCTTTTTCCAACACCCACGCCTTTTGACTTTGATCTTGACTTCATTGGCAACGTGGCACATGCCACAACGctcaagaacaacaacgatgatAGCTTCAATGTGGCATCTCTGCCTCCGCCCCTACTGTTAAATGGCAGCGATAAATTGCTGACTGCAGCGCTGGAGCCGTCGCCCGTTAAGGATTTGCGTCCACGTCTGCCCCGTACCCCCATCTATGTGTGCAAGCAATGCAATCAAACGTTCGACGAGCTGGCCAAGCTGTTGCAACACGAGCTGCAGCAACATTCCAGTGGCACGATGTCCACGCCACGCAGCAGCTATCAGCATCAGTGCAAGATCTGTAATGCCTCCTATCGCACTGTGACCCTGCTCAATTATCACATGAAGCGACATGCGCCGGTCAAAGTGCCCTGCAAGGAGTTTCAGGTTAGCACGGAATTGAAGCCCGATCATGTTCAGTCCGATCATCGTGGAAATAGTGGTCCACTCAAGTGTGGCATCGATGGCTGCCGGAAGACCTTCAATTACAAGCATCATTTAAAGCGACATCAGACCGCATCGCATACGCCTGTACAATATATTTGTCCGGAGTGTGGACGCGATATGCTGACTAGTCTGTATCTGAGGAATCACATGTCCATGCACCGGGGCACCCACTCCTACAAGTGCCCCAAGTGCGTGCGCACCTATATGCGCCGTAATCCtTTCCGTCGACATGCGTTGCGGGAGCACAAATGGGAATTGACGGATGCggaaattgataaaatatattgtgaaAATGATTCAACGCCATCAATAATATTGCGCGATTTGCGGTGA
Protein Sequence
MAQKRLKAADMEINYKFTCRCCLKSEAEFFKLDSLIDCGNDDASDNDNDASSTTKLPLLRLLLFCMRTENLPELPQYICVECRKSLQIAYYFIQNGLRAHEILCRKLCPGKLQTKPRINGQHLALRLEAKAGAALLDTHREKPLKCKICGEVIHNRLELKHHLRMHSESRHKCKLCNFVTLKHRQLLEHYRKSHGLTTAQIEHQLKIRRSLQAAANDDGQVKVCTMEDMELLIPTVLTPEDFTHPQLDADQLRDIEQQLTSSSLGLANTTAASTEPVTANASGSSANMSIGAEFLVMPDGSLQQVNDAGVVFEYIDDSKNAANITTTTSTTTNVTLESLLSDSKTDLTYDAMNIDLSPMVVDNALPQITVKPKGRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCTFYSLRSADLIQHYTSEHNICVSDTKASQVEKSPMLTAMLTDRNRIFSCDMCLFETPSGGQLRLHYSDKHLIVPSEIQLRPSWIRDQQDGNAKLKSGDAKTQPDIPLGIKYPTMTQCAAATIATTTAKTTSMVQQPQAITTTTTAVTSTGGINVVVDASSLFYAATAAENVGTTAAITTATTGATATTGATATTTTGASSTDSSTIAIFPEQCLATTAKAAITNPQEASNQAVTTSTTTTTTNPNTSTFGDMQEFIDNTDVAAICTIPADDMPVDGDDIVIDNNNISLDFDAENLFEEFEDVEVGEEVDDDDAEEDDEDEDEDDADNDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKKMPTRDMVQAKGDKVAVPCTAIEKININADKNPLLMCAKCPFECELDVDMRKHLNAHHGINDGVSMHANEVFIIRKLPYECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQALQLTTSSAATTTTATTTTTLPNNGSDGNKATANAVVESSNNGNIDVDVDLGDGGDGKCDFTPTTQQSAVSTLFPTPTPFDFDLDFIGNVAHATTLKNNNDDSFNVASLPPPLLLNGSDKLLTAALEPSPVKDLRPRLPRTPIYVCKQCNQTFDELAKLLQHELQQHSSGTMSTPRSSYQHQCKICNASYRTVTLLNYHMKRHAPVKVPCKEFQVSTELKPDHVQSDHRGNSGPLKCGIDGCRKTFNYKHHLKRHQTASHTPVQYICPECGRDMLTSLYLRNHMSMHRGTHSYKCPKCVRTYMRRNPFRRHALREHKWELTDAEIDKIYCENDSTPSIILRDLR