Ddiv003338.1
Basic Information
- Insect
- Drosophila dives
- Gene Symbol
- -
- Assembly
- GCA_035042365.1
- Location
- JAWNLJ010000143.1:633251-638160[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00012 0.0087 16.4 1.3 1 23 394 416 394 416 0.98 2 12 3.4 2.4e+02 2.5 1.0 1 23 422 445 422 445 0.90 3 12 6.4 4.5e+02 1.6 0.4 1 23 474 497 474 497 0.89 4 12 0.0038 0.27 11.7 2.1 5 23 781 799 778 799 0.92 5 12 0.044 3.1 8.4 1.4 1 23 805 828 805 828 0.98 6 12 1.6 1.1e+02 3.5 1.6 3 23 866 886 864 887 0.80 7 12 0.0002 0.014 15.8 0.7 1 23 908 931 908 931 0.97 8 12 0.01 0.74 10.4 0.4 1 23 1093 1116 1093 1116 0.92 9 12 0.00031 0.022 15.2 3.0 1 23 1130 1152 1130 1152 0.98 10 12 0.0014 0.1 13.1 4.0 2 23 1184 1208 1183 1208 0.90 11 12 0.02 1.4 9.5 0.1 1 23 1213 1235 1213 1235 0.97 12 12 0.0058 0.41 11.2 1.3 1 23 1241 1264 1241 1264 0.96
Sequence Information
- Coding Sequence
- ATGGCGCATAAACGTTTGAAAACAGCGGACATGGAAGTTAATTACAAATTCGCATGTCGCTGTTGCCTCAAATCGGAGGCGGAATTCTTCAAGCTGGACTCACTCATCGACTGCGGCAACTTTGATGCCAATGACAATGACGATGATGCCTCGCCGCAAACAAAATTGCCCCTGTGGCGTTTACTGCTCTTCTGCATGCACACCGAAAATCTGCCCGAGCTGCCACAATACATTTGCGTGGAATGCCGAAAAAGTTTACAAATAGCCTACTGTTTCATAAAGAACAGTTTACGTGCCCATGAAGTATTGTGTCGCAAACTGTGCCCGGGCAAGCTGCAAACCAAACCGCGCATAAACGGACAACACTTAGCCCTAAGGATCGAGGAAAAAGCTGGCGGAGCGATGCTGGGAACGCAAAGGGATAAACCcctaaaatgcaaaacattcGGTGAGATTATACCTAATCGCTTGGAGCTCAAACATCATCTAGGATTTCATTCAGAGTCTCGACATTTGTGTAAATTGTGTAATTTCGTAACGCATAAGCATCGCCAGCTGCTGCAACACTATCGCAAATCGCATGGCTTGACAACGGCCCAAATTGAGCATCAGTTGAAAAAACGTAGATCTATACAGGCGACAGCAGCTGCATCCACAGAAACGCCTGTTGCTGCGGATGATGATGGTCAGGTAAAAGTGTGCACATTAGAGGACATGGAGCTGCTGATACCCACTGTGTTGACACCCGAGGATTTCATACATCCACGACTCGATGCGGATCAATTGCGTGACATTGAACAGCAATTGACGAGTAGCTCGCTTGCCTTGCCCAACAACACAGCTGCATTTACGGAACCAGTTTCGGCAAATGTTACCGGAAATAGTGCCAATATGAGCATAGGTGCGGAGTTTCTGGTCATGCCCGATGGCTCGTTGCAGCAGGTTAATGCTGCTGGCGTTGTCTTCGAATATATTGATGATAGTGCAAGTGCGGCAAAACCAGCAACATCCACATCGACCAATGTGAGTTTGGAGAGCCTGTTGAGTGACTCGAAAACAGATTTAACCTATGATCCAATGGCTATTGATCTGAGTCTTATGGTTGCCGATAATATACTTCCACAGATAACAGTCAAGCCCAAGGTGCGACCAGCGCCATTGTCAACTGGTGCCCTgaaacacaaatgcaaactgTGCCCCAAAGCATTTCCGACGGTTGCACGCCTCAAATCTCACCAGCTAACGCATAGCCATTTACCTAAATTCTATTGCGATCAGTGCAAATATTATTCGCTGCGCAGCGCCGATCTCATCCAGCATTATACAAACGAGCATAATATGTGCGTCAGCGATGCGAAAGCTAGTCAAGTGGAGAAGTTACCAACGCTGACGGCAATGTTAACGGATCGCAATCGTATCTTTTCCTGCGATATGTGTCTGTTTGACACGCCCAGCGGAGGTCAGCTGCGGCAGCATTACAGTGATAAACATCTAATTGTACCCAGTGAGATACAGCTACGTCCTAGCTGGATCAGGGATCAGCAAGATGGATATACGAAACTGAAAAGTGGCGACGGCAACCCACAACCAGACATTCCGCTGGGTATTAAATATCCAAACATGACGCAGTCTGAAAcggcagcaacggcaacagcgacaacaacaaaaatggtGCAACAGCCGcaggcaataacaacaacaactacggcTGTGAATTCGACGGGTGGCATAAATGTTGTTGTGGATGCCAGTTCATTATTCTATGCAGCAACTGCTGACGAAAATGTAGCAGTAACaggtgcaacagcaacaacaacgggcGGAATAGCAACAGATTCAAGCACAATTGCAATATTTCCAGAGCAATGCctgtcaacaacaaaaacaacaacagcaaaggtTTCGACAACAAATCAACAGGAGGCAAGCGTTCAGGcagtgacagcaacaacaacaccaacaaatcCCAATACTAGCACATTTGGTGATATGCAGGAGTTTATAGATAATACAGATGTGGCTGCCATATGCACAATACCCGGCGATGATATGCCTGTGGATGGCGATGATATCGTCAtcgataataataacattagtCTGGATTTTGATGCTGAAAATCTATTTGAGGAATTTGAAGATGTCGAAGTTGGCGAAGAAGTTGACGATGAGGACGCTGACGAGGATGaagaggatgaggatgaggatgatgcGGACAATGATGATGAGAATGATAACAATAATGCGGCTGCCGATCAAAATCTCTTGCTAACCagcgacgatgacgatgtGGATGACTTTGACGACGAACAATCGAAGGATCTGCAGAAACCctattgcatattttgcaacaaaaagtttACCAGTCAATACAAGTTCGAAAATCACATGTTTGTGCATCGCGGTTTGGCCCCCTATCGCTGTGAGCTGTGCACCAATCTGTACAATATGAAACGCCTGCTCATACGACACTATAAAACAGTTCATAAAAAGATGCCCACGAGAGACATGGTGCAGGCCAAGGGCGACAAGGTTGCCGTGCCGTGTATGCATATCGAAAAGATTAATATAAACGCGGGCAGAAatccTTCACTGATGTGCGCCAAATGTCCATTTGAATGTGAGCAAGATGTAGATATGCGCAAGCACTTAAATGCCCATCATGGCATCAACGATGGCGTTTCCTTGCATGCCAACGAGGTGTTTATTATACGCAAACTGCCTTATGAGTGTCCACGCTGTGTTCGTTCGTTTGCGGCAAAGCGAACGTTAACACGCCACTTGCAGCGTAGCCATTTGGTGGATACAATCATTGAGATGCAGGCGCTGCAATTGACCCCAAGTTCGGAGGCAACGACAACCACCACTTTACCGAACAATGCCAGCGATAGCAGTAAAGCCACAGCACATGCGGTTGACGAGTCGTCGAAAAATTTCGATGGCGATGGTAGCGATGAAAAATGCGATGATCAAGTGCTTGACAAGGATGCTGGATCAGAAATGGAAAATTCCGATACAGAAGTGAATATAAAAGACGCAATAAAAGATGTTACAAAGGTGACAGCAACATCAGACTCAGCAATCCCAGCACTTTTTCCAACGCCCACGTCCTTTGACTTTGATCTGGACTTCattggcaaaaacaacaacgatgaTAGCTTCAATGTGGCATCTCTGCCTCCGCCTCTACTGCTAAATGGCAGCGATAAGTTGCTGACTGCCGCTCTGGAGCTGTCGCCCGTTAAAGATTTGCGTTCACGTCTGCCCCGTACCCCAATTTATGTGTGCAAGCAATGCAATCAAACATTCGACGAGCTGGCCAAGCTGTTGCAGCACGAGCTGCAGCAACATTCCAGTGGCACAATATCATCGCCACGCAGCAGCCATCAGCATCAGTGCAAGATCTGTAATGCCTCCTATCGCACTGTGACCCTGCTCAATTATCACATGAAGCGACATACGCCAGTCAAAGTGCCCTGCAAAGATTTTCAGGTTAGCGCGGAGTTGGAGCAGCATGAACCGTCCGATCATCGTGGCAATAGTAGCCCACTCAAATGTGGCATCGATGGGTgcagaaaaacatttaattacaagCATCATTTAAAGCGACATCAGACCGCATCGCACACGCctgtgaaatatatttgtccAGTGTGCGGACGAGATTTGCTGACCAGCCTGTATTTAAGGAATCACATGACTATGCACCGGGGCACCCACTCCTATAAGTGCCCCAAGTGCGTGCGTACCTATATGAGGCGTAATCCTTTCCGTCGACATGCGTTGCGGGAGCACAAATGGGAATTGACGGATGAggaaattgataaaatatattgtgaaaatgattcaacaccatcaacaataTTGCGCGATTTACGGTGA
- Protein Sequence
- MAHKRLKTADMEVNYKFACRCCLKSEAEFFKLDSLIDCGNFDANDNDDDASPQTKLPLWRLLLFCMHTENLPELPQYICVECRKSLQIAYCFIKNSLRAHEVLCRKLCPGKLQTKPRINGQHLALRIEEKAGGAMLGTQRDKPLKCKTFGEIIPNRLELKHHLGFHSESRHLCKLCNFVTHKHRQLLQHYRKSHGLTTAQIEHQLKKRRSIQATAAASTETPVAADDDGQVKVCTLEDMELLIPTVLTPEDFIHPRLDADQLRDIEQQLTSSSLALPNNTAAFTEPVSANVTGNSANMSIGAEFLVMPDGSLQQVNAAGVVFEYIDDSASAAKPATSTSTNVSLESLLSDSKTDLTYDPMAIDLSLMVADNILPQITVKPKVRPAPLSTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCKYYSLRSADLIQHYTNEHNMCVSDAKASQVEKLPTLTAMLTDRNRIFSCDMCLFDTPSGGQLRQHYSDKHLIVPSEIQLRPSWIRDQQDGYTKLKSGDGNPQPDIPLGIKYPNMTQSETAATATATTTKMVQQPQAITTTTTAVNSTGGINVVVDASSLFYAATADENVAVTGATATTTGGIATDSSTIAIFPEQCLSTTKTTTAKVSTTNQQEASVQAVTATTTPTNPNTSTFGDMQEFIDNTDVAAICTIPGDDMPVDGDDIVIDNNNISLDFDAENLFEEFEDVEVGEEVDDEDADEDEEDEDEDDADNDDENDNNNAAADQNLLLTSDDDDVDDFDDEQSKDLQKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKKMPTRDMVQAKGDKVAVPCMHIEKININAGRNPSLMCAKCPFECEQDVDMRKHLNAHHGINDGVSLHANEVFIIRKLPYECPRCVRSFAAKRTLTRHLQRSHLVDTIIEMQALQLTPSSEATTTTTLPNNASDSSKATAHAVDESSKNFDGDGSDEKCDDQVLDKDAGSEMENSDTEVNIKDAIKDVTKVTATSDSAIPALFPTPTSFDFDLDFIGKNNNDDSFNVASLPPPLLLNGSDKLLTAALELSPVKDLRSRLPRTPIYVCKQCNQTFDELAKLLQHELQQHSSGTISSPRSSHQHQCKICNASYRTVTLLNYHMKRHTPVKVPCKDFQVSAELEQHEPSDHRGNSSPLKCGIDGCRKTFNYKHHLKRHQTASHTPVKYICPVCGRDLLTSLYLRNHMTMHRGTHSYKCPKCVRTYMRRNPFRRHALREHKWELTDEEIDKIYCENDSTPSTILRDLR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00557462;
- 90% Identity
- iTF_00499196;
- 80% Identity
- -