Doch009944.2
Basic Information
- Insect
- Drosophila ochracea
- Gene Symbol
- -
- Assembly
- GCA_035044125.1
- Location
- JAWNML010000058.1:1486450-1491446[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0067 0.42 11.1 3.6 2 23 145 166 144 166 0.97 2 13 0.00014 0.0089 16.3 1.3 1 23 407 429 407 429 0.98 3 13 7.4 4.6e+02 1.5 1.9 1 23 435 458 435 458 0.93 4 13 9.6 6.1e+02 1.1 0.3 1 23 487 510 487 510 0.89 5 13 0.0044 0.27 11.7 2.1 5 23 803 821 800 821 0.92 6 13 0.05 3.1 8.3 1.4 1 23 827 850 827 850 0.98 7 13 7.5 4.7e+02 1.5 1.0 2 19 890 908 886 910 0.55 8 13 0.0047 0.3 11.5 0.4 1 23 930 953 930 953 0.97 9 13 0.015 0.96 10.0 0.8 1 23 1173 1196 1173 1196 0.92 10 13 0.00035 0.022 15.1 3.0 1 23 1210 1232 1210 1232 0.98 11 13 0.0016 0.1 13.0 4.0 2 23 1265 1289 1264 1289 0.90 12 13 0.094 5.9 7.5 0.2 1 23 1294 1316 1294 1316 0.96 13 13 0.0066 0.41 11.1 1.3 1 23 1322 1345 1322 1345 0.96
Sequence Information
- Coding Sequence
- ATGGCGCACAAACGTTTGAAAGCAGCGGACATGgaaatcaattacaaattcGCATGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTCAAGCTGGACGCTCTCATCGACTGTGGCAACTATGAtgccaatgacaatgacaatgatgCATCGTCCACAACAAAATTGCCCTTGTTGAGTTTACTGCTCTTCTGCATGCGCACCGAAAATCTACCAGAGCTGCCGCAATACATTTGCGTGGAATGCCGAAAAAGTTTACAAATTGCCTACTATTTCATACAGAATGGTTTGCGTGCCCACGAAATACTGTGTCGCAAACTGTGTCCGGGCAAGCTGCAAACCAAACCGCGCATCAACGGACAACATTTAGCCCTAAGGATCGAGGCAAAAGCTGGCGCAGCGTTGCAGGACACGCACGGGGAGAAACCcctaaaatgcaaaaaatgcgGCGAGGTTATCCACAATCGCTTAGAGCTGAAACATCATCTACGAATGCATtcagAGTCTCGACACCAGTGTAAATTGTGCAACTTTGTACCGCTTAAGCATCGCAAGCTGCTGGAGCACTATCACAAATCGCATGGGTTGACAACGGCTCAAATTGAACATCAGTTGAAAATACGAAGATCGCTGCAGGTGGCTgcgagtacaacaacaaaagctacaACAGCTGCATCTACAGAAACgcctgccgttgctgctgctgtagatGATGATGGTCAGGTGAAGGTGTGCACAATGGAGGACATGGAGCTGCTGATACCGACAGTGTTGACGCCCGAGGATTTCACGCATCCACAACTAGATGCAGATCAATTGCGTGACATTGAACAGCAATTGACAAGCAGCTCGCTGGGATTGGCCAACACCACAGCTGCTTCCACGGAACCAGTGACGGCAAATGCCAGCGGAAGCAGTGCCAATATGAGCATAGGTGCAGAATTTCTGGTCATGCCCGATGGCTCGTTGCAGCAGGTGAATGATGCTGGCGTTGTCTTCGAATATATTGATGATAGTAAAAATGCGGCCaccagagcaacaacaacaaacacaacgaCCAATGTGACGCTGGAGAGCCTGTTGAGTGACTCGAAAACTGATTTAATCTATGATGCAATGGACATTGATCTGAGTCCTATGGTTGTCGATAATGCGCTGCCACAGATAACAGtcAAGCCCAAGGGGCGAGTAGCGCCAGCATCAACTGGTGCCCTGAAACACAAATGCAAGCTGTGTCCCAAAGCATTTCCGACGGTGGCCCGCCTCAAATCTCACCAGCTAACGCATAGCCATTTACCTAAATTCTATTGTGATCAGTGCACATTTCATTCTCTGCGCAGCGCCGATCTCATCCAGCATTATACGAGCGAGCATAATATATGCGTTAGCGATACGAAAGCTAGTCAAGTGGAGAAGTCACCAATGCTAACAGCAATGTTAACGGATCGCAATCGCATCTTCTCCTGCGATATGTGTCTGTTTGAGACGCCGAGCGGCGGTCAGCTGCGCTTGCATTACAGTGATAAGCATCTCATTGTGCCCAGTGAGATACAGCTGCGTCCCAGCTGGATCAGGGATCAGCAGGATGGCAATACGAAGCTGAAAAGTGGCGATGCCAACACACAACCAGACATTCCACTGGGCATTAAATATCCAACCATGACGCACtgtgcagcagccacaatggcaacaacgacggcgaaaacaacaagcatggtgcaacagccgcaggcaataacaacaacaacaacagcagtgacTTCCACGGGTGGTATCAATGTTGTTGTCGATGCCAGCTCATTGTTCtatgcagcaactgctgctgaaAATGTAGGAACAACGGTTGCAACAACGGCTGCGACCACgggtgcaacagcaacaacaacaacgggcGCAACAGCTACAAATTCAAGCACAATTGCAATATTTCCAGAACAATgcctggcaacaacaacagcaaaagcagcaataacaaatcaaCAGGAGGCAAGCAATCAGGCAgtgacaacatcaacaacaataacaactaatcCCAATACTAGCACATTTGGTGATATGCAGGAGTTTATAGATAATACAGATGTGGCAGCCATATGCACAATACCCGCCGACGATATGCCTGTGGATGGTGATGATATCGTcatcgataataataatattagtcTGGATTTTGATGCCGAAAATCTATTTGAGGAATTTGAAGATGTCGAAGTTGGCGAAGTAgttgacgatgacgacgctGAGGAGGatgacgaggatgaggatgaggatgatgcGGACAATGAAGATGAGAATGATAACAATGATGCGGCTGCCGATCAAAATCTGTTGCTAACcagcgacgatgacgatgtggATGACTTTGACGACGAACAATCGAAGCATCTGCAGAAACCCTATTGCATCttttgcaacaaaaagtttACCAGCCAATATAAGTTTGAGAATCATATGTTTGTGCATCGCGGTTTGGCACCATATCGCTGCGAGCTGTGCACCAATCTGTACAATATGAAACGTCTGCTCATACGACACTATAAAACGGTTCACAAAAAGATGCCCACGCGAGACATGGTGCAGGCCAAGGGCGACAAGGTTGCCGTACCGTGTACGGCTATCGAAAAGATAATTATAAATGCGGACAAAAatcCTTTGCTGATGTGCGCCAAGTGTCCTTTTGAATGTGAGCTGGATGTGGATATGCGCAAGCATTTAAATGCCCATCATGGCATCAATGATGGCGTTTCCATGCATGCCAACGAAGTGTTTATCATACGCAAACTGCCCTATGAGTGTCCACGCTGCATTCGTTCATTTGCGGCAAAGCGAACGTTGATACGCCACTTGCAGCGTAGCCATTTGGTGGATACAATCATTGAGATGCAGGCGCTTCAATTGACAACTAGTTCGGCGGCAACGACAACCacagcgacgacaacaaccacattgCCGAACAATGTCAGCGATGGAAATAAGGCCATAGCAAATGCGGTTGTGGAGTCGTCCAACAATGGCAATATCGATGTCGATGTTGATCTTGGCGATGGCGGCGATGGAAAATGCGAAGAGCAATCATTGGTCAAGGATACAGGATCAGAAATGGAAAATTCCGATACAGAAATGGATACAAAGGGTTCACTGAAAGAAGTTATAaatgcggcagcaacaacagatgTAAGAGAAGCACCAACTGTCgcagaagcaaaaacaaccacTGCCACTGTAAAAACAGATGCTTctcccacaacaacaacaataacaacagattttacaccaacaacacaacaGTCTGCAGTGTCAACGCTTTTTCGAATGCCCACGCCTTTTGACTTTGATCTGGACTTCATTGGCAACGTGGCACATGCCACAACGctcaagaacaacaacgatgatAGCTTCAATGTGGCATCTCTGCCTCCGCCCCTACTGCTAAATGGCAGCGATAAATTGCTGACTGCCGCGCTGGAGCCGTCGCCCGTTAAGGATTTGCGTCCACGTCTGCCCCGTACCCCCATCTATGTGTGCAAGCAATGCAATCAAACGTTCGACGAGCTGACCAAGCTGTTGCAGCACGAGCTGCAGCAACATTCCAGTGGCACGATGTCCACGCCACGCAGCAGCTATCAGCATCAGTGCAAGATCTGTAATGCCTCCTATCGCACTGTGACCCTGCTGAATTATCACATGAAGCGACATGCGCCAGTCAAAGAGCCGTGCAAGGAGTTTCAGGTTAGCACGGAATTGGAGCCCGGTCATGTTCAGTCCGATCATCGTGGAAATAGTGGTCCACTCAAGTGTGGCATCGATGGCTGCCGGAAGACCTTCAATTACAAGCATCATTTAAAGCGACATCAGACCGCATCGCATACGCCTGTACAATATATTTGTCCGGAGTGCGGACGCGATATGCTAACCAGTCTGTATCTGAGGAATCACATGTCCATGCACCGGGGCACCCACTCCTACAAGTGCCCCAAGTGCGTGCGTACCTATATGCGCCGTAATCCtTTCCGTCGACATGCGTTGCGGGAGCACAAATGGGAATTGACGGATGCggaaattgataaaatatattgtgaaAATGATTCAACGCCATCAATAATATTGCGCGATTTGCGGTGA
- Protein Sequence
- MAHKRLKAADMEINYKFACRCCLKSEAEFFKLDALIDCGNYDANDNDNDASSTTKLPLLSLLLFCMRTENLPELPQYICVECRKSLQIAYYFIQNGLRAHEILCRKLCPGKLQTKPRINGQHLALRIEAKAGAALQDTHGEKPLKCKKCGEVIHNRLELKHHLRMHSESRHQCKLCNFVPLKHRKLLEHYHKSHGLTTAQIEHQLKIRRSLQVAASTTTKATTAASTETPAVAAAVDDDGQVKVCTMEDMELLIPTVLTPEDFTHPQLDADQLRDIEQQLTSSSLGLANTTAASTEPVTANASGSSANMSIGAEFLVMPDGSLQQVNDAGVVFEYIDDSKNAATRATTTNTTTNVTLESLLSDSKTDLIYDAMDIDLSPMVVDNALPQITVKPKGRVAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCTFHSLRSADLIQHYTSEHNICVSDTKASQVEKSPMLTAMLTDRNRIFSCDMCLFETPSGGQLRLHYSDKHLIVPSEIQLRPSWIRDQQDGNTKLKSGDANTQPDIPLGIKYPTMTHCAAATMATTTAKTTSMVQQPQAITTTTTAVTSTGGINVVVDASSLFYAATAAENVGTTVATTAATTGATATTTTGATATNSSTIAIFPEQCLATTTAKAAITNQQEASNQAVTTSTTITTNPNTSTFGDMQEFIDNTDVAAICTIPADDMPVDGDDIVIDNNNISLDFDAENLFEEFEDVEVGEVVDDDDAEEDDEDEDEDDADNEDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKKMPTRDMVQAKGDKVAVPCTAIEKIIINADKNPLLMCAKCPFECELDVDMRKHLNAHHGINDGVSMHANEVFIIRKLPYECPRCIRSFAAKRTLIRHLQRSHLVDTIIEMQALQLTTSSAATTTTATTTTTLPNNVSDGNKAIANAVVESSNNGNIDVDVDLGDGGDGKCEEQSLVKDTGSEMENSDTEMDTKGSLKEVINAAATTDVREAPTVAEAKTTTATVKTDASPTTTTITTDFTPTTQQSAVSTLFRMPTPFDFDLDFIGNVAHATTLKNNNDDSFNVASLPPPLLLNGSDKLLTAALEPSPVKDLRPRLPRTPIYVCKQCNQTFDELTKLLQHELQQHSSGTMSTPRSSYQHQCKICNASYRTVTLLNYHMKRHAPVKEPCKEFQVSTELEPGHVQSDHRGNSGPLKCGIDGCRKTFNYKHHLKRHQTASHTPVQYICPECGRDMLTSLYLRNHMSMHRGTHSYKCPKCVRTYMRRNPFRRHALREHKWELTDAEIDKIYCENDSTPSIILRDLR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00557462;
- 90% Identity
- iTF_00518733;
- 80% Identity
- -