Dcon003457.1
Basic Information
- Insect
- Drosophila conformis
- Gene Symbol
- -
- Assembly
- GCA_035041375.1
- Location
- JAWNLE010000429.1:22714-27622[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.012 0.77 10.4 2.5 2 23 141 162 140 162 0.97 2 11 0.00014 0.0093 16.4 1.3 1 23 402 424 402 424 0.98 3 11 3.5 2.3e+02 2.6 0.8 1 23 430 453 430 453 0.92 4 11 0.0049 0.32 11.6 2.5 5 23 772 790 769 790 0.93 5 11 0.051 3.3 8.4 1.4 1 23 796 819 796 819 0.98 6 11 0.0032 0.21 12.2 0.7 1 23 899 922 899 922 0.97 7 11 0.0088 0.57 10.8 0.6 1 23 1122 1145 1122 1145 0.94 8 11 0.00036 0.023 15.2 3.0 1 23 1159 1181 1159 1181 0.98 9 11 0.0017 0.11 13.1 4.0 2 23 1213 1237 1212 1237 0.90 10 11 0.048 3.1 8.5 0.3 1 23 1242 1264 1242 1264 0.97 11 11 0.0046 0.3 11.7 1.4 1 23 1270 1293 1270 1293 0.97
Sequence Information
- Coding Sequence
- ATGGCGCACAAACATTTGAAAGCAGCGGACATGgaaatcaattacaaattcGCATGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTCAAGCTGGACTCCCTCATCGACTGTGACAACGATGATGCCAATGATGCCTCGTCCCCAACCAAATTGCCCCTGTTGCGTTTACTGCTCTTTTGCATGCGCACCGAAAATCTGCCCGAGCTGCCGCAATACATTTGCGTGGATTGCCGTAAAAGTTTGCAAATTGCCTACTATTTCATACAAAACGGTTTGCGTGCCCACGAAATATTGTGTCGCAAACTGTGTCCGGGCAAGCTGCAAACCAAACCGCGCATCAACGGACAACACTTAGCCCTAAGGATCGAGACAAAAGCTGGCGCAGCGTTGCTGGACACGCACAGGGAGAAATCCCTAAAATGCAAAGTATGCGGTGAGATTATCCACAATCGTCTGGAGCTCAAACATCATCTACGAATGCATTCagAGTCTCGACATCGGtgtaaattgtgcaattttgtAACGCTTAAGCATCGCCAGCTGCTGGAACACTATCGTAAATCGCATGGCTTGACAACGGCCCAAATTGAGCATCAGTTGAAATTACGAAAATCGCTGCAGGCGGCTGccagtgcaacaacaacaagaaaagcgACAGCAGTTTTATCCACAGaagctcctgctgctgcggatgATGATGGTCAGGTGAAGGTGTGCACAATGGAGGACATGGAGCTGCTGATACCCACAGTGATGAGGCCCGAGGATTTCACGTACCCACAACTGGATGCGGATCAATTGCGTGACATTGAACAGCAATTGACGAGTAGCTCGCTGGGATTGCCCAACCCAACAGCTGCATTCACGGAACCAGTGACGGCAAAAGCCAGCGGAAGCAGTGCCAATATGAGCATAGGTGCAGAGTTTCTGGTCTTGCCGGATGGCACGTTGCAGCAGGTGAATGATGCTGGCGTTGTCTTCGAATATATTGATGATAGTAAAAATACGGCCAgcacagtaacagcaacaaccacatcgACCAATGTGACGCTGGAGAGCCTGTTGAGTGACTCGAAAACCGATTTAACCTATGATTCAATGGCCATTAATCTGAGTCACATGGCTGTCGATAATGCGCTGCCACAGATAACAGTCAAGCCCAAGGCGCGACCAGTGCCAGCATCAACTGGTGCCCTgaaacacaaatgcaaactgTGCCCGAAAGCATTTCCGACGGTGGCACGCCTCAAATCTCATCAGCTAACGCATAGCCACTTACCCAAATTCTATTGTGATCAATGCACATATTATTCGCTGCGCAGCGCTGATCTCATCCAGCATTATACGAGCGAGCATAATGTATGCGTTAGCGATACGAAAGCTAGTCAAGTGGAAAAGTCACCAATGCTGACGGCAATGTTAACGGATCGCAATCGCATCTTCTCCTGCGATATGTGTCTTTTTGAGACGCCGAGCGGCGCTCAGCTGCGCTTGCATTACAGTGATAAGCATCTCATTGTGCCCAGTGAGATACAGCTGCGTCCCAGCTGGATCAGGGACCAGCAGGATGGCAATGCAAAACTGAAAAGTGGCGACGGCATCACAACACCAGACATTCCTCTGGGCATTAAATATCCAACCGTGACGCAgtgtgcagcagccacaacggcggcgacaacaacaagcatgGTGCAAGAGCcgcaagcaataacaacaacaacaacggctgTGACTTCAAAGGGTGGCATCAATGTCGTCGTGGATGCCAGCTCTTTATtctatgcaacaacaacaacgggcgCAACATCAACAGATTCAAGCACAATTGCAATATTTCCAGAGCAATGCCTgtctaaaacaacaacaaccatagcaaaggcagctgcaacaaatcaACCGGAAGCAAGCAgtcaggcagcaacaacagcaacaactcccAATACTAGCACGTTTGGTGATATGCAGGAGTTTATAGATAATACAGATGTGGCAGCCATATGCACAATACCCGCCGACGATATGCCTGTGGATGGCGATGATATCGTcatcgataataataatattagtcTGGATTTTGATGCCGAAAATCTATTTGAGGAATTTGAAGATGCCGAAGTTGGCGAGGAGGTTGACGATGTCGACGCTGACGAAgatgacgaggatgaggatgaggatgatgcggataatgatgatgagaaTGATAACAATGATGCGGCTGCCGATCAAAATCTATTGCTAACcagcgacgatgacgatgtggATGACTTTGACGACGAACAATCGAAGCATCTGCAGAAACCctattgtatattttgcaacaaaaagtttACCAGCCAATACAAGTTCGAGAATCACATGTTTATGCATCGCGGTTTGGCACCATACCGCTGTGAGCTGTGCACCAATCTGTACAATATGAAACGCCTGCTCATACGACACTATAAAACAGTTCACAAAACGATGCCCACGCGGGACATGGTGCAGGCCAAGGGCGACAAGGAAGACGTGCCGTGTGCGGCTATcgaaaagataaatataaatgcggGCAAAAatcCCTTGCTGATGTGCGCCAAGTGTCCCTTTGAAGGTGAGCTGGATGTGGATATGCTCAAGCATTTAAATGCCCATCATGGCATCAACGATGGGGTTTCCATGCATTCCAACGAAGCGTTTATCATACGCAAACTGCCTTATGAGTGTCCACGCTGTATTCGTTCATTTGCGGCAAAGCGAACGTTGACACGCCATTTACAGCGTAGCCATTTGGTGGATACAATCATTGAGATGCAGGCGCTGCAATTGACAACCAGTTCGGCGGCAACGACAACCacagcgacgacaacaaccacattgCCTAACAATACCAGCGATGCCAGTACAGCCACAGCACATGCGGTTGAAGAGCCATGCAACAAGAGCAATATCGATGTTGATCTTGGCGATGGCGGCGATAGAAAATGCGAAATGGAAAATTCCGATACAGAAATGGATACAAAAGGCGCAATAAAAGAAGTTATAAATGCGGTAGCAACAACTGGCGCAAGAGAAGCAACTAGAAAAACTGCCACTGCAAAAGCAGATGCTTCTGCAACACCAAAAAGCACAACAGACTTTACACCAACAACGCAACAGTCTGCAGTCTCATCGCTTTTTCCAACACCCACGCCTTTTGACTTTGATCTTGACTTCATTGGCAACGTGGCAGATGCCACAACGctgaagaacaacaacgatgacaGCTTCAATGTGGCATCTCTGCCTCCGCCTTTACTGCTAAATGGCAGCGATAAGTTGCTGACTGCCGCTCTGGAGCCGTCGCCCGTTAAGGATTTGCGTCCACGTCTGCCCCGTACCCCCATCTATGTGTGCAAGCAATGCAATCAAACGTTCGACGAGCTGGCCAAACTGTTGCagcatgagcagcagcaacattccAGTGGCACGATGTCCTCGCCACGCAGCAGCTATCAGCATCAGTGCAAGATCTGTAATGCCTCCTATCGCACTGTGACCCTCCTCAATTATCACATGAAGCGACATGCGCCGGTCAAAGTGCCCTGCAAGGAGTTTCAGGTTAGCACGGAGTTGGAGCAACATGTTCCGTCCGATCATCGTGCCAATAGTGGTCCACTCAAATGTGGCATCGATGGGTGTAGGAAAACCTTCAATTACAAGCATCATTTGAAGCGACATCAGACCGCATCGCATACGCCTGTGCAATATATTTGTTCGGTGTGCGGGCGAGATTTGCTGACCAGTCTGTATCTGAGGAATCACATGTCCATGCACCGGGGCACCCACTCCTACAAGTGCCCCAAGTGCGTGCGCACCTATATGCGCCGTAATCCTTTCCGTCGACATGCGATGCGGGAACACAAATGGGAGTTGACGGATGCGGAAattgataaaatatattgtgaAAATGATTCAACGCCATCAAAAATATTGCGCGACTTGCGGTGA
- Protein Sequence
- MAHKHLKAADMEINYKFACRCCLKSEAEFFKLDSLIDCDNDDANDASSPTKLPLLRLLLFCMRTENLPELPQYICVDCRKSLQIAYYFIQNGLRAHEILCRKLCPGKLQTKPRINGQHLALRIETKAGAALLDTHREKSLKCKVCGEIIHNRLELKHHLRMHSESRHRCKLCNFVTLKHRQLLEHYRKSHGLTTAQIEHQLKLRKSLQAAASATTTRKATAVLSTEAPAAADDDGQVKVCTMEDMELLIPTVMRPEDFTYPQLDADQLRDIEQQLTSSSLGLPNPTAAFTEPVTAKASGSSANMSIGAEFLVLPDGTLQQVNDAGVVFEYIDDSKNTASTVTATTTSTNVTLESLLSDSKTDLTYDSMAINLSHMAVDNALPQITVKPKARPVPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCTYYSLRSADLIQHYTSEHNVCVSDTKASQVEKSPMLTAMLTDRNRIFSCDMCLFETPSGAQLRLHYSDKHLIVPSEIQLRPSWIRDQQDGNAKLKSGDGITTPDIPLGIKYPTVTQCAAATTAATTTSMVQEPQAITTTTTAVTSKGGINVVVDASSLFYATTTTGATSTDSSTIAIFPEQCLSKTTTTIAKAAATNQPEASSQAATTATTPNTSTFGDMQEFIDNTDVAAICTIPADDMPVDGDDIVIDNNNISLDFDAENLFEEFEDAEVGEEVDDVDADEDDEDEDEDDADNDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFMHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKTMPTRDMVQAKGDKEDVPCAAIEKININAGKNPLLMCAKCPFEGELDVDMLKHLNAHHGINDGVSMHSNEAFIIRKLPYECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQALQLTTSSAATTTTATTTTTLPNNTSDASTATAHAVEEPCNKSNIDVDLGDGGDRKCEMENSDTEMDTKGAIKEVINAVATTGAREATRKTATAKADASATPKSTTDFTPTTQQSAVSSLFPTPTPFDFDLDFIGNVADATTLKNNNDDSFNVASLPPPLLLNGSDKLLTAALEPSPVKDLRPRLPRTPIYVCKQCNQTFDELAKLLQHEQQQHSSGTMSSPRSSYQHQCKICNASYRTVTLLNYHMKRHAPVKVPCKEFQVSTELEQHVPSDHRANSGPLKCGIDGCRKTFNYKHHLKRHQTASHTPVQYICSVCGRDLLTSLYLRNHMSMHRGTHSYKCPKCVRTYMRRNPFRRHAMREHKWELTDAEIDKIYCENDSTPSKILRDLR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00557462;
- 90% Identity
- iTF_00521717; iTF_00607396; iTF_00495431; iTF_00620160; iTF_00610186; iTF_00497709; iTF_00567105; iTF_00528376; iTF_00559053; iTF_00574373; iTF_00482546; iTF_00593427; iTF_00560601; iTF_00597722;
- 80% Identity
- -