Basic Information

Insect: Drosophila heteroneura
Gene Symbol: -
Assembly: GCA_035042245.1
Location: JAWNLO010000458.1:12845-18158[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.016 1 9.9 0.8 2 23 145 166 144 166 0.97

2 13 0.00013 0.0084 16.4 1.3 1 23 409 431 409 431 0.98

3 13 7.3 4.6e+02 1.5 0.8 1 23 437 460 437 460 0.88

4 13 9.1 5.8e+02 1.2 0.3 1 23 489 512 489 512 0.89

5 13 0.0041 0.26 11.7 2.1 5 23 811 829 808 829 0.92

6 13 0.047 3 8.4 1.4 1 23 835 858 835 858 0.98

7 13 7.1 4.5e+02 1.5 1.0 2 19 898 916 894 918 0.55

8 13 0.003 0.19 12.2 0.7 1 23 938 961 938 961 0.97

9 13 0.011 0.71 10.3 0.4 1 23 1125 1148 1125 1148 0.92

10 13 0.00033 0.021 15.2 3.0 1 23 1162 1184 1162 1184 0.98

11 13 0.0015 0.097 13.1 4.0 2 23 1217 1241 1216 1241 0.90

12 13 0.089 5.7 7.5 0.2 1 23 1246 1268 1246 1268 0.96

13 13 0.0062 0.39 11.1 1.3 1 23 1274 1297 1274 1297 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.016	1	9.9	0.8	2	23	145	166	144	166	0.97
2	13	0.00013	0.0084	16.4	1.3	1	23	409	431	409	431	0.98
3	13	7.3	4.6e+02	1.5	0.8	1	23	437	460	437	460	0.88
4	13	9.1	5.8e+02	1.2	0.3	1	23	489	512	489	512	0.89
5	13	0.0041	0.26	11.7	2.1	5	23	811	829	808	829	0.92
6	13	0.047	3	8.4	1.4	1	23	835	858	835	858	0.98
7	13	7.1	4.5e+02	1.5	1.0	2	19	898	916	894	918	0.55
8	13	0.003	0.19	12.2	0.7	1	23	938	961	938	961	0.97
9	13	0.011	0.71	10.3	0.4	1	23	1125	1148	1125	1148	0.92
10	13	0.00033	0.021	15.2	3.0	1	23	1162	1184	1162	1184	0.98
11	13	0.0015	0.097	13.1	4.0	2	23	1217	1241	1216	1241	0.90
12	13	0.089	5.7	7.5	0.2	1	23	1246	1268	1246	1268	0.96
13	13	0.0062	0.39	11.1	1.3	1	23	1274	1297	1274	1297	0.96

Sequence Information

Coding Sequence: ATGGCGCAAAAACGTTTAAAAGCAGCGGACATGgaaatcaattacaaattcGCATGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTCAAGCTGGACTCCCTCATCGACTGTGGCAACGATGATGCcaacgacaatgacaatgatgcATCGTCCACAACAAAATTGCCCCTGTTGCGTTTACTGCTCTTCTGCATGCGCACCGAAAATCTCCCCGAGCTGCCGCAATACATTTGCGTGGAATGCCGAAAAAGTTTACAAATTGCCTACTATTTCATACAGAACGGTTTGCGTGCCCACGAAATATTGTGTCGCAAGCTGGTTCCGAGCAAGCTGCAAACCAAACCGCGCATCAACGGACAACATTTAGCCCTAAGGATCGAGGCAAAAGCTGGCGCAGCGTTGCTGGACACGCACAGGGAGAAACCcctaaaatgcaaaatatgcgGTGAGGTTATCCTCAATCGCTTGGAGCTGAAACATCATCTGCGAATGCATtcagAATCTCGACACCAGTGTAAATTGTGCAACTTTGTAACGCTGAAGCATCGCCAGCTGCTGGAGCACTATCGCAAATCGCATGGCTTGACAACGGCTCAAATTGAGCATCAGTTGAAAATACGAAGATCGCTGCAGGCGGCTGCCagtacagcaacaacaataaaagctacAACAGCTGCATCTACAGAaacgcctgctgctgctgctgcagacgaTGATGGTCAGGTGAAGGTGTGTACAATGGAGGACATGGAGCTGCTGATACCCACAGTGTTGACGCCCGAGGATTTCACGCATCCACAACTAGATGCGGATCAATTGCGTGACATTGAACAGCAATTGACGAGCAACTCGCTGGGATTGGCCAACACCACAACTGCGCCCACGGAACCGGTGACGGCAAATGCCAGTGGAAGCAGTGCCAATATGAGCATAGGTGCAGAATTTCTGGTCATGCCCGATGGCTCGTTGCAGCAGGTGAATGATGCTGGCGTTGTCTTCGAATATATTGATGATAGTAAAAATGCGgccaaaataacaacaacaacaacaagcacaacgaCCAATGTAACGCTGGAGAGCCTGTTGAGTGACTCGAAAACCGATTTAACCTATGATGCAATGGACATTGATCTGAGTCCTATGGTTGTCGATAATGCGCTGCCACAGATAACAGTCAAGCCCAAGGGGCGACCAGCGCCAGCGTCTACTGGTGCCCtgaaacacaaatgcaaactgTGTCCCAAAGCATTTCCGACGGTGGCACGCCTCAAATCTCACCAGCTAACGCACAGCCATTTACCTAAATTCTATTGTGATCAGTGCACATTTTATTCTCTGCGCAGCGCCGATCTCATCCAGCATTATACGAGCGAGCATAATATATGCGTTAGCGATACGAAAGCTAGTCAAGTGGAGAAGTCACCAATGCTGACGGCAATGTCAACGGATCGCAATCGCATCTTCTCCTGCGATATGTGTCTGTTTGAGACGCCGAGCGGCGGTCAGCTGCGATTGCATTACAGTGATAAGCATCTCATTGTGCCCAGTGAGATACAGTTGCGTCCCAGCTGGATCAGGGATCAGCAGGATGGCAATGCGAAGCTGAAAAGTGGCGATGCCAACACACAACCAGACATTCCACTGGGCATTAAATATCCAACCATGACGCAGTGTGCTGTAgccacaatggcaacaacggcggcgaaaacaacaagcatggtgcaacagccgcaggcaataacaacaacaacaacggcggtGACTTCCACGGGTGGCATCAATGTTGTTGTCGATGCCAGCTCATTGTTCTATGCAGCAACTACTGCTGAAAAAGTAGGAACAACGGCTGCAATAACGACTGCAACAACgggtgcaacagcaacaacgggtgcaacagcaacaacaacaacgggcgCATCAGCTACAGATTCAAGCACAATTGCAATATTTCCAGAACAATgcctggcaacaacaacagcaaaagcagccatAACAAATCCACAAGAGGCAAGCAATCAGGCAgtgacaacatcaacaacaacaacaacaaatcccaATACTAGCACATTTGGTGATATGCAGGAGTTTATAGATAATACAGATGTGGCAGCTATATGCACAATACCCGCCGACGATATGCCTGTGGATGGCGATGATATCGTcatcgataataataatattagtcTGGATTTTGATGCCGAAAATCTATTTGAGGAATTTGAAGATGTCGAAGTTGGCGAAGAGgttgacgatgacgatgctgAGGAGgatgacgaggatgaggatgaggatgatgcGGACAATGATGATGAGAATGATAACAATGATGCGGCTGCCGATCAAAATCTCTTGCTAACcagcgacgatgacgatgtggATGACTTTGACGACGAACAATCGAAGCATCTGCAGAAACCCTATTGCATcttttgcaacaaaaagttTACCAGCCAATACAAGTTCGAGAATCATATGTTCGTGCATCGCGGTTTGGCACCCTATCGCTGTGAGCTGTGCACTAATCTGTACAATATGAAACGTCTGCTCATACGACACTATAAAACGGTTCACAAAAAGATGCCCACGCGGGACATGGTGCAGGCCAAGGGCGACAAGGTAGCCGTGCCGTGTACGGCTATCgaaaagataaatataaatgcggACAAAAatCCCTTGCTGATGTGCGCCAAGTGTCCCTTTGAATGTGAGCTGGATGTGGATATGCGCAAGCATTTAAATGCTCATCATGGCATCAACGATGGCGTTTCCATGCATGCCAACGAAGTGTTTATCATACGCAAACTGCCCTATGAATGTCCACGCTGCATTCGTTCATTTGCGGCAAAGCGAACGTTGACACGCCATTTGCAGCGTAGCCATTTGGTGGATACAATCATTGAGATGCAGGCGCTTCAATTGACAACCAGTTCGGCGGCAACGACAACcacagcgacgacaacaaccacattgCCGAACAATGTCAGCGATGGTAATAAGGCCACAGCAAATGCGGTTGTGGAGTCGTCCAATAATGGCAatatcgatgtcgatgtcgatctTGGCGATGGCGGCGATCGAAAATGCGATGCTTcttccacaacaacaacaaccacaacagactttacaccaacaacacaacaGTCTGCAGTGTCAACACTTTTTCCAACACCCACGCCTTTTGACTTTGATCTTGACTTCATTGGCAACGTGGCACATGCCACAACGCTCAAGAACAACACCGATGATAGCTTCAATGTGGCATCTCTGCCTCCGCCCCTACTGTTAAATGGCAGCGATAAATTGCTGACTGCAGCGCTGGAGCCGTCGCCCGTTAAGGATTTGCGTCCACGTCTGCCTCGTACCCCCATCTATGTGTGCAAGCAATGCAATCAAACGTTTGACGAGCTGGCCAAGCTGTTGCAGCACGAACTGCAGCAACATTCCAGTGGCACGATGTCCACGCCACGCAGCAGCTATCAGCATCAGTGCAAGATCTGTAATGCCTCATATCGCACTGTGACCCTGCTTAATTATCACATGAAGCGACATGCGCCGGTCAAAGTGCCCTGCAAGGAGTTTCAGGTTAGCACGGAATTGAAGCCCGATCATGTTCAGTCCGATCATCGTGGAAATAGTGGTCCACTCAAGTGTGGCATCGATGGCTGCCGGAAGACCTTCAATTACAAGCATCATTTAAAGCGACATCAGACCGCATCGCATACGCCTGTACAATATATTTGTCCGGAGTGCGGACGCGATATGCTGACCAGTCTGTATCTGAGGAATCACATGTCCATGCACCGGGGCACCCACTCCTACAAGTGCCCCAAGTGCGTGCGCACCTATATGCGCCGTAATCCtTTCCGTCGACATGCGTTGCGGGAGCACAAATGGGAATTGACGGATGCggaaattgataaaatatattgtgaaAATGATTCAACGCCATCAATAATATTGCGCGATTTGCGGTGA
Protein Sequence: MAQKRLKAADMEINYKFACRCCLKSEAEFFKLDSLIDCGNDDANDNDNDASSTTKLPLLRLLLFCMRTENLPELPQYICVECRKSLQIAYYFIQNGLRAHEILCRKLVPSKLQTKPRINGQHLALRIEAKAGAALLDTHREKPLKCKICGEVILNRLELKHHLRMHSESRHQCKLCNFVTLKHRQLLEHYRKSHGLTTAQIEHQLKIRRSLQAAASTATTIKATTAASTETPAAAAADDDGQVKVCTMEDMELLIPTVLTPEDFTHPQLDADQLRDIEQQLTSNSLGLANTTTAPTEPVTANASGSSANMSIGAEFLVMPDGSLQQVNDAGVVFEYIDDSKNAAKITTTTTSTTTNVTLESLLSDSKTDLTYDAMDIDLSPMVVDNALPQITVKPKGRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCTFYSLRSADLIQHYTSEHNICVSDTKASQVEKSPMLTAMSTDRNRIFSCDMCLFETPSGGQLRLHYSDKHLIVPSEIQLRPSWIRDQQDGNAKLKSGDANTQPDIPLGIKYPTMTQCAVATMATTAAKTTSMVQQPQAITTTTTAVTSTGGINVVVDASSLFYAATTAEKVGTTAAITTATTGATATTGATATTTTGASATDSSTIAIFPEQCLATTTAKAAITNPQEASNQAVTTSTTTTTNPNTSTFGDMQEFIDNTDVAAICTIPADDMPVDGDDIVIDNNNISLDFDAENLFEEFEDVEVGEEVDDDDAEEDDEDEDEDDADNDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKKMPTRDMVQAKGDKVAVPCTAIEKININADKNPLLMCAKCPFECELDVDMRKHLNAHHGINDGVSMHANEVFIIRKLPYECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQALQLTTSSAATTTTATTTTTLPNNVSDGNKATANAVVESSNNGNIDVDVDLGDGGDRKCDASSTTTTTTTDFTPTTQQSAVSTLFPTPTPFDFDLDFIGNVAHATTLKNNTDDSFNVASLPPPLLLNGSDKLLTAALEPSPVKDLRPRLPRTPIYVCKQCNQTFDELAKLLQHELQQHSSGTMSTPRSSYQHQCKICNASYRTVTLLNYHMKRHAPVKVPCKEFQVSTELKPDHVQSDHRGNSGPLKCGIDGCRKTFNYKHHLKRHQTASHTPVQYICPECGRDMLTSLYLRNHMSMHRGTHSYKCPKCVRTYMRRNPFRRHALREHKWELTDAEIDKIYCENDSTPSIILRDLR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00557462;
90% Identity: iTF_00499866; iTF_00596222; iTF_00583266; iTF_00517290; iTF_00557462; iTF_00576631; iTF_00564953; iTF_00553332; iTF_00599149; iTF_00616493; iTF_00502096; iTF_00570710; iTF_00486152; iTF_00513783; iTF_00577343; iTF_00542720; iTF_00498433;
80% Identity: -