Basic Information

Insect: Drosophila sproati
Gene Symbol: -
Assembly: GCA_018904355.1
Location: JAEIFY010000050.1:4038342-4043537[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0023 0.16 12.3 2.4 2 23 145 166 144 166 0.97

2 13 0.00011 0.0075 16.4 1.3 1 23 407 429 407 429 0.98

3 13 5.8 3.9e+02 1.6 1.9 1 23 435 458 435 458 0.93

4 13 7.6 5.1e+02 1.2 0.3 1 23 487 510 487 510 0.89

5 13 0.0035 0.23 11.8 2.1 5 23 719 737 716 737 0.92

6 13 0.039 2.6 8.4 1.4 1 23 743 766 743 766 0.98

7 13 5.9 4e+02 1.6 1.0 2 19 806 824 802 826 0.55

8 13 0.0037 0.25 11.6 0.4 1 23 846 869 846 869 0.97

9 13 0.0054 0.37 11.1 0.6 1 23 1089 1112 1089 1112 0.93

10 13 0.00028 0.019 15.2 3.0 1 23 1126 1148 1126 1148 0.98

11 13 0.0013 0.086 13.1 4.0 2 23 1181 1205 1180 1205 0.90

12 13 0.075 5 7.6 0.2 1 23 1210 1232 1210 1232 0.96

13 13 0.0052 0.35 11.2 1.3 1 23 1238 1261 1238 1261 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0023	0.16	12.3	2.4	2	23	145	166	144	166	0.97
2	13	0.00011	0.0075	16.4	1.3	1	23	407	429	407	429	0.98
3	13	5.8	3.9e+02	1.6	1.9	1	23	435	458	435	458	0.93
4	13	7.6	5.1e+02	1.2	0.3	1	23	487	510	487	510	0.89
5	13	0.0035	0.23	11.8	2.1	5	23	719	737	716	737	0.92
6	13	0.039	2.6	8.4	1.4	1	23	743	766	743	766	0.98
7	13	5.9	4e+02	1.6	1.0	2	19	806	824	802	826	0.55
8	13	0.0037	0.25	11.6	0.4	1	23	846	869	846	869	0.97
9	13	0.0054	0.37	11.1	0.6	1	23	1089	1112	1089	1112	0.93
10	13	0.00028	0.019	15.2	3.0	1	23	1126	1148	1126	1148	0.98
11	13	0.0013	0.086	13.1	4.0	2	23	1181	1205	1180	1205	0.90
12	13	0.075	5	7.6	0.2	1	23	1210	1232	1210	1232	0.96
13	13	0.0052	0.35	11.2	1.3	1	23	1238	1261	1238	1261	0.96

Sequence Information

Coding Sequence: ATGGCGCAAAAATGTTTGAAAGCAGCGGACATGGAAATCAATTACAAATTCGCATGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTCAAGCTGGACTCTCTCATCGACTGTGGCAACGATGATGCCAATGACAATGACAATGATGCATCGTCCACAACAAAATTGCCCCTGTTGAGTTTACTGCTCTTCTGCATGCGCACCGAAAATCTACCAGAGCTGCCGCAATACATATGCGTGGAATGCCGAAAAAGTTTACAAATTGCCTACTATTTCATACAGAATGGTTTGCGTGCTCACGAAATACTGTGTCGCAAACTGTGTCCGGGCAAGCTGCAAACCAAACCGCGCATCAACGGACAACATTTAGCCCTAAGGATCGAGGCAAAAGCTGGCGCAGCGTTGCAGGACACGCACGGGGAGAAACCCCTAAGATGCAAAATATGCGGCGAGGTTATCCACAATCGCTTAGAGCTGAAACATCATCTACGAATGCATTCAGAGTCTCGACACCAGTGTAAATTGTGCAACTTTGTAACGCTTAAGCATCGCCAGCTGCTGGAGCACTATCGCAAATCGCATGGCTTGACAACGACTCAAATTGAACATCAGTTGAAAATACGAAGATCGCTGCAGGTGGCTGCCAGAACAACAACAAAAGCCACAACAGCTGCATCTACAGAAACGCCTGCCGCTGCTGCTGCTTTAGATGATGATGGTCAGGTGAAGGTGTGTACAATGGAGGACATGGAGCTGCTGATACCGACAGTGTTGACGCCCGAGGATTTCACGCATCCACAACTAGATGCGGATCAATTGCGTGACATTGAACAGCAATTGACAAGCAGCTCGCTGGGATTGGCCAACACCACAGCTGCTTCCACGAAACCAATGACGGCAAATGCCAGCGGAAGCAGTGCCAATATGAGCATAGGTGCAGAATTTCTGGTCATGCCCGATGGCTCGTTGCAGCAGGTGAATGATGCTGGCGTTGTCTTCGAATATATTGATGATAGTAAAAATGCGGCCACCAGACCAACAACAACAAACACAACATCCAATGTGACGCTGGAGAGCCTGTTGAGTGACTCGAAAACCGATTTAATCTATGATGCAATGGACATTGATCTGAGTCCTATGGTTGTCGATAATGCACTGCCGCAGATAACAGTCAAGCCCAAGGGGCGACCAGCGCCAGCATCAACTGGTGCCCTGAAACACAAATGCAAGTTGTGTCCCAAAGCATTTCCGACGGTGGCCCGCCTCAAATCTCACCAGCTAACGCATAGCCATTTACCTAAATTCTATTGTGATCAGTGCACATTTCATTCTCTGCGCAGCGCCGATCTCATCCAGCATTATACGAGTGAGCATAATATATGTGTTAGCGATACGAAAGCTAGTCAAGTGGAGAAGTCACCAATGCTGACGGCAATGTTAACGGATCGCAATCGCATCTTCTCCTGCGATATGTGTCTGTTTGAGACGCCGAGCGGCGGTCAGCTGCGCTTGCATTACAGTGATAAGCATCTCATTGTGCCCAGTGAGATACAGCTGCGTCCCAGCTGGATCAGGGATCAGCAGGATGGCAATACGAAGCTGAAAAGTGGCGATGCCAACACACAACCGGACATTCCACTGGGCATTAAATATCCAACCATGACGCAGAGTGCAGCAGCCACAATGGCAACAACGACGGCGAAAACAACAAGCATGGTGCAACAGCCGCAGGCAATAACAACAACAACAACGGCAGTGACTTCCACGGGTGGTATCAATGTTGTTGTAGATGCCAGCTCATTGTTCTATGCAGCAACTGCTGCTGAAAATGTAGGAACAACGGCTGCAACAACGGCTGCGACCACGGGTGCAACAGCAACAACAACAACGGGCGCAACAGCTACAAATTCAAGCACAATTGCAATATTTCCAGAACAATGCCTGGCAACAACAACAGCAAAAGCAGCAATAACAAATCAACAGGAGGCAAGCAATCAGGCAGTGACAACATCAACAACAATAACAACAAATCCCAATACTAGCACATTTGGTGATATGCAGGAGTTTATAGATAATACAGATGTGGCAGCCATATGCACAATACCCGCCGACGATATGCCTGTGGATGGCGATGATATCAAACCCTATTGCATCTTTTGCAACAAAAAGTTTACCAGCCAATACAAGTTTGAGAATCATATGTTTGTGCATCGCGGTTTGGCACCATATCGCTGCGAGCTGTGCACCAATCTGTACAATATGAAACGTCTGCTCATACGACACTATAAAACGGTTCACAAAAAGATGCCCACGCGAGACATGGTGCAGGCCAAGGGCGACAAGGTAGCCGTACCGTGTACGGCTATCGAAAAGATAAATATAAATGCGGACAAAAATCCTTTGCTGATGTGCGCCAAGTGTCCCTTTGAATGTGAGCTGGATGTGGATATGCGCAAGCATTTAAATGCCCATCATGGCATCAATGATGGCGTTTCCATGCATGCCAACGAAGTGTTTATCATACGCAAACTGCCCTATGAGTGTCCACGCTGCATTCGTTCATTTGCGGCAAAGCGAACGTTGATACGCCACTTGCAGCGTAGCCATTTGGTGGATACAATCATTGAGATGCAGGCGCTTCAATTGACAACCAGTTCGGCGGCAACGACAACGACAGCGACGACAACAACCACATTGCCGAACAATGCCAGCGATGGCAATAAGGCCATAGCAAATGCGGTTGTGGAGTCGTCCAATAATGGCAATATCGATGTCGATGTCGATCTTGGCGATGGCAGCGATGGAAAATGCGAAGAGCAAGCATTGGTCAAGGATACAGGATCAGAAGTGGAAAATTCCGATACAGAAATGGATACAAAGGGTTCACTAAAAGAAGCTATAAATGCGACAGCAACAACAGATGTAAGAGAAGCACCAACTGTAGCAGAAGCAAAAACAACCACTGCCACTGTAAAAACAGATGCTTCTCCCACAACAACAACAATAACAACAGATTTTACACCAACAACACAACAGTCTGCAGTGTCAACGCTTTTTCGAATGCCCACGCCTTTTGACTTTGATCTTGACTTCATTGGCAACGTGGCACATGCCACAACGCTCAAGAACAACAACGATGATAGCTTCAATGTGGCATCTCTGCCTCCGCCCCTACTGCTAAATGGCAGCGATAAATTGCTGACTGCCGCGCTGGAGCCGTCACCTGTTAAGGATTTGCGTCCACGTCTGCCCCGTACCCCCATCTATGTGTGCAAGCAATGCAATCAAACGTTCAACGAGCTGGCCAAGCTGTTGCAGCACGAGCTGCAACAACATTCCAGTGGCACGATGTCCACGCCACGCAGCAGCTATCAGCATCAGTGCAAGATCTGTAATGCCTCCTATCGCACTGTGACCCTGCTGAATTATCACATGAAGCGACATGCGCCAGTCAAAGAGCCGTGCAAGGAGTTTCAGGTTAGCACGGAATTGGAGCCCGGTAATGTTCAGTCCGATCATCGTGGAAATAGTGGTCCACTCAAGTGTGGCATCGATGGCTGCCGGAAGACCTTCAATTACAAGCATCATTTAAAGCGACATCAGACCGCATCGCATACGCCTGTACAATATATTTGTCCGGAGTGCGGACGCGATATGCTAACCAGTCTGTATCTGAGGAATCACATGTCCATGCACCGGGGCACCCACTCCTACAAGTGCCCCAAGTGCGTGCGTACCTATATGCGCCGTAATCCTTTCCGTCGACATGCGTTGCGGGAGCACAAATGGGAATTGACGGATGCGGAAATTGATAAAATATATTGTGAAAATGATTCAACGCCATCAATAATATTGCGCGATTTGCGGTGA
Protein Sequence: MAQKCLKAADMEINYKFACRCCLKSEAEFFKLDSLIDCGNDDANDNDNDASSTTKLPLLSLLLFCMRTENLPELPQYICVECRKSLQIAYYFIQNGLRAHEILCRKLCPGKLQTKPRINGQHLALRIEAKAGAALQDTHGEKPLRCKICGEVIHNRLELKHHLRMHSESRHQCKLCNFVTLKHRQLLEHYRKSHGLTTTQIEHQLKIRRSLQVAARTTTKATTAASTETPAAAAALDDDGQVKVCTMEDMELLIPTVLTPEDFTHPQLDADQLRDIEQQLTSSSLGLANTTAASTKPMTANASGSSANMSIGAEFLVMPDGSLQQVNDAGVVFEYIDDSKNAATRPTTTNTTSNVTLESLLSDSKTDLIYDAMDIDLSPMVVDNALPQITVKPKGRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCTFHSLRSADLIQHYTSEHNICVSDTKASQVEKSPMLTAMLTDRNRIFSCDMCLFETPSGGQLRLHYSDKHLIVPSEIQLRPSWIRDQQDGNTKLKSGDANTQPDIPLGIKYPTMTQSAAATMATTTAKTTSMVQQPQAITTTTTAVTSTGGINVVVDASSLFYAATAAENVGTTAATTAATTGATATTTTGATATNSSTIAIFPEQCLATTTAKAAITNQQEASNQAVTTSTTITTNPNTSTFGDMQEFIDNTDVAAICTIPADDMPVDGDDIKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKKMPTRDMVQAKGDKVAVPCTAIEKININADKNPLLMCAKCPFECELDVDMRKHLNAHHGINDGVSMHANEVFIIRKLPYECPRCIRSFAAKRTLIRHLQRSHLVDTIIEMQALQLTTSSAATTTTATTTTTLPNNASDGNKAIANAVVESSNNGNIDVDVDLGDGSDGKCEEQALVKDTGSEVENSDTEMDTKGSLKEAINATATTDVREAPTVAEAKTTTATVKTDASPTTTTITTDFTPTTQQSAVSTLFRMPTPFDFDLDFIGNVAHATTLKNNNDDSFNVASLPPPLLLNGSDKLLTAALEPSPVKDLRPRLPRTPIYVCKQCNQTFNELAKLLQHELQQHSSGTMSTPRSSYQHQCKICNASYRTVTLLNYHMKRHAPVKEPCKEFQVSTELEPGNVQSDHRGNSGPLKCGIDGCRKTFNYKHHLKRHQTASHTPVQYICPECGRDMLTSLYLRNHMSMHRGTHSYKCPKCVRTYMRRNPFRRHALREHKWELTDAEIDKIYCENDSTPSIILRDLR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00557462;
90% Identity: iTF_00518733;
80% Identity: -