Dpul008212.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila pullipes
Gene Symbol
-
Assembly
GCA_035043795.1
Location
JAWNMT010000635.1:3974614-3979834[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.011 0.67 10.4 1.1 2 23 145 166 144 166 0.97
2 13 0.00014 0.0087 16.4 1.3 1 23 409 431 409 431 0.98
3 13 7.5 4.7e+02 1.4 0.8 1 23 437 460 437 460 0.88
4 13 9.4 5.9e+02 1.1 0.3 1 23 489 512 489 512 0.89
5 13 0.0042 0.27 11.7 2.1 5 23 805 823 802 823 0.92
6 13 0.043 2.7 8.5 1.7 1 23 829 852 829 852 0.98
7 13 7.3 4.6e+02 1.5 1.0 2 19 892 910 888 912 0.55
8 13 0.0031 0.19 12.1 0.7 1 23 932 955 932 955 0.97
9 13 0.027 1.7 9.2 0.4 1 23 1172 1195 1172 1195 0.91
10 13 0.00067 0.043 14.2 2.7 1 23 1209 1231 1209 1231 0.98
11 13 0.0016 0.099 13.0 4.0 2 23 1264 1288 1263 1288 0.90
12 13 0.11 7.1 7.2 0.3 1 23 1293 1315 1293 1315 0.96
13 13 0.0064 0.4 11.1 1.3 1 23 1321 1344 1321 1344 0.96

Sequence Information

Coding Sequence
ATGGCGCACAAACGTTTGAAAGCAGCGGACATGgaaatcaattacaaattcGCATGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTCAAGCTGGACTCTCTCATCGACTGTGGCAACGATGATgccaatgacaatgacaatgatgcATCGTCCACAACAAAATTGCCCCTGTTGCGTTTACTGCTCTTCTGCATGCGCACCGAAAATCTACCAGAGCTGCCGCAATACATTTGCGTGGAATGCCGAAAAAGTTTACAAATTGCCTACTATTTCATACAGAATGGTTTGCGTGCCCACGAAATACTGTGTCGCAAACTGTGTCCGAGCAAGCTGCAAACCAAACCGCGCATGAACGGACAACATTTAGCCCTAAGGATCGAGGCAAAAGCTGGCAGAGCGTTGCAGGACACGCACAGGGAGAAACCcctaaaatgcaaaatatgcgGTGAGGTTATCCACAATCGCTTACAGGTGAAACAGCATCTACGAATGCATTCAGAGTCTCGACACCAGTGTAAATTGTGCAACTTTGTAACGCTTAAGCATCGCCAGCTGCTGGAGCACTATCGCAAATCGCATGGCTTGACAACGGCCCAAATTGAGCATCAGTTGAAAATACGAAGATCGCTGCAGGTGGCTGccagtacaacaacaaaagctacaACAGCTGCATCTACAGAAACgcctgccgctgctgccgccgcagaTGATGATGGTCAGGTGAAGGTGTGCACAATGGAGGACATGGAGCTGCTGATACCGACAGTGTTGACGCCCGAGGATTTCACGCATCCACAACTAGATGCGGATCAATTGCGTGACATTGAACAGCAATTGACAAGCAGCTCGCTGGGATCGGCCAACACCACAGCTGCTTCCACGGAATCAGTGACGGCAAATGCCAGCGGAAGCAGTGCCCATATGAGCATAGGTGCAGAATTTCTGGTCATGCCCGATGGCTCGTTGCAGCAGGTGAATGATGCTGGCGTTGTCTTCGAATATATTGATGATAGTAAAAATGCGGCcagcagagcaacaacaacaaacacaacgacCAATGTGACGCTGGAGAGCCTGTTGAGCGACTCGAAAACCGATTTAATCTATGATGCAATGGACATTGATCTGAGTCCTATGGTTGTCGATAATGCGCTGCCACAGATAACAGtcAAACCCAAGGGGCGAccagcgccagcgccagcgTCAACTGGTGCCATGAAACACAAATGCAAGCTGTGTCCCAAAGCATTTCCGACGGTGGCCCGCCTCAAATCTCACCAGCTAACGCATAGCCACTTACCTAAATTCTATTGTGATCAGTGCACATTTTATTCTCTGCGCAGCGCCGATCTCATCCAGCATTATACGAGCGAGCATAATATATGCGTTAGGGATACGAAAGCTAGTCAAGTGGAGAAGTCACCAATGCTGACGGCAATGTTAACGGATCGCAATCGCATCTTTTCCTGCGATATGTGTCTGTTTGAGACGCCGAGCGGCGGTCAGCTGCGCTTGCATTACAGTGATAAGCATCTCATTGTGCCCAGTGAGGTACAGCTGCGTCCCAGCTGGATCAGGGATCAGCTGGATGGCAATGCGAAGCTGAAAAGTGGCGATGCCAACACACAACCAGACATTCCACTGggcattaaatATCCAACCATGACGCAGtgtgcagcagccacaatggcaacaacgacggcgaaaacaacaagcatggtgcaacagccgcaggcaataacaacaacaacaacggcagtgACTTCCACGGGTGGTATCAATGTTGTTGTCGATGCCAGCTCATTGTTCtatgcagcaactgctgctgaaaATGTAGGAACAACGGCGGCAACAACGACTGCGACCACGGgtgcaccagcaacaacaacaacgggcGCAACAGCTACAAATTCAAGCACACTTGCAATATTTCCAGAACAATgcctggcaacaacaacaacagcaaaagcagcaataacaaatcaaCAGGAGGCAAGCAATCAGGCAgtgacaacatcaacaacaacaacaaatcccAATACTAGCACATTTGGTGATATGCAAGAGTTTATAGATAATACGGATGTGGCAGCCATATGCACAATACCCGCCGACGATATGCCTGTGGATGGCGATGATATCGTcatcgataataataatattagtcTGGATTTTGATGCCGAAAATCTATTTGAGGAATTTGAAGATGTCGAAGTTGGCGAAGAGgttgacgatgatgacgcTGAAGAGGatgacgaggatgaggatgaggatgatgcGGAGAATGATGATGagaatgataataatgatgcgGCTGCCGATCAAAATCTCTTGCTAACcagcgacgatgacgatgtggATGACTTTGACGACGAACAATCGAAGCATCTGCAGAAACCctattgcatattttgcaacaaaaagtttACCAGCCAATACAAGTTTGAGAATCATATGTTTGTGCATCGCGGTTTGGCACCCTATCGCTGCGAGCAGTGCACCAATCTGTACAATATGAAACGTCTGCTCATACGACACTATAAAACGGTTCACAAAAAGATGCCCACGCGAGACATGGTGCAGGCCAAAGGCGACAAGGTAGCCGTACCGTGTACGGCTATcgaaaagataaatataaatgcggACAAAAagcCTTTGCTGATGTGCGCCAAGTGTCCCTTTGAATGTGAGCTGGATGTGGATATGCGCAAGCATTTAAATGCCCATCATGGCATCAATGATGGCGTTTCCATTCATGCCAACGAAGTGTTTATCATACGCAAACTGCCATATGAGTGTCCACGCTGCATTCGTTCATTTGCGGCAAAGCGAACGTTGACACGCCACTTGCAGCGTAGCCATTTGGTGGATACAATCATTGAGATGCAGGCGCTTCAATTGACAACCAGTTCGGCGGCAACGACAACcacagcgacgacaacaaccacattgCCAAACAATGCCAGCGATGGCAATAAGGCCAAACCAAATGCGGTTGTGGAGTCGTCCAATAATGGCAatatcgatgtcgatgtcgatctTGGCGATGGCGGCGTTGGAAAATGCGAAGAGCAAGCATTGGTCAAGGATACAGGATCAGAAATGGAAAACTCCGCCACAGAAATGGATACAAAGGGTTCACTAAAAGAAGTTATAaatgcggcagcaacaacagacgtAAGAGAAGCACCAACTGTagcagaagcaaaaacaaccacTGCCACTGTAAAAACAGATGCTTctcccacaacaacaacaaccacaacagattttacaccaacaacacaacaGTCTGCAGTGTCAACGCTTTTTCCAACTTTTGACTTTGATCTTGACTTCATTGGCAATGTGGCACATGCCACAACGctaaagaacaacaacgatgatAGCTTCAATGTGGCATCTCTGCCTCCGCCCCTACTGCTAAATGGCAGCGATAAATTGCTGACTGCCGCGCTGGAGCCGTCGCCCGTTAAGGATTTGCGTCCACGTCTGCCCCGTACCCCCATCTATGTGTGCAAGCAATGCAATCAAACGTTCGACGAGCTGCCCAAGCTGTTGCAGCACGAGCTGCAGCAACATTCCAGTGGCACGAAGTCCTCGCTACGCAGCAGCTACCAGCATCAGTGCAAGATCTGTAATGCCTCCTATCGCACTGTGACCCTGCTGAATTATCATATGAAGCAACATGCGCCGGTCAAAGTGCCGTGCAAGGAGTTTCAGGTTAGCACGGAAGTGGATCCCGATCATGTTCAGTCCGATCATCGTGGCAATAGTGGTCCACTCAAGTGTGGCATCGACGGCTGCCGGAAGACCTTCAATTACAAGCATCATTTAAAGCGACATCAGACCGCATCGCATACGCCTGTTCAATATATTTGTCCCAAGTGCGGACGCGATATGCTGACCAGTCTGTATCTGAGGAATCACATGTCCATGCACCGGGGCACCCACTCCTACAAATGCCCCAAGTGCGTGCGTACCTATATGCGCCGTAATCCtTTTCGTCGACATGCGTTACGGGAGCACAAATGGGAATTGACGGATGCggaaattgataaaatatattgtgaaAATGATTCAACGCCATCAATAATATTGCGCGATGTGCGGTGA
Protein Sequence
MAHKRLKAADMEINYKFACRCCLKSEAEFFKLDSLIDCGNDDANDNDNDASSTTKLPLLRLLLFCMRTENLPELPQYICVECRKSLQIAYYFIQNGLRAHEILCRKLCPSKLQTKPRMNGQHLALRIEAKAGRALQDTHREKPLKCKICGEVIHNRLQVKQHLRMHSESRHQCKLCNFVTLKHRQLLEHYRKSHGLTTAQIEHQLKIRRSLQVAASTTTKATTAASTETPAAAAAADDDGQVKVCTMEDMELLIPTVLTPEDFTHPQLDADQLRDIEQQLTSSSLGSANTTAASTESVTANASGSSAHMSIGAEFLVMPDGSLQQVNDAGVVFEYIDDSKNAASRATTTNTTTNVTLESLLSDSKTDLIYDAMDIDLSPMVVDNALPQITVKPKGRPAPAPASTGAMKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCTFYSLRSADLIQHYTSEHNICVRDTKASQVEKSPMLTAMLTDRNRIFSCDMCLFETPSGGQLRLHYSDKHLIVPSEVQLRPSWIRDQLDGNAKLKSGDANTQPDIPLGIKYPTMTQCAAATMATTTAKTTSMVQQPQAITTTTTAVTSTGGINVVVDASSLFYAATAAENVGTTAATTTATTGAPATTTTGATATNSSTLAIFPEQCLATTTTAKAAITNQQEASNQAVTTSTTTTNPNTSTFGDMQEFIDNTDVAAICTIPADDMPVDGDDIVIDNNNISLDFDAENLFEEFEDVEVGEEVDDDDAEEDDEDEDEDDAENDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCEQCTNLYNMKRLLIRHYKTVHKKMPTRDMVQAKGDKVAVPCTAIEKININADKKPLLMCAKCPFECELDVDMRKHLNAHHGINDGVSIHANEVFIIRKLPYECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQALQLTTSSAATTTTATTTTTLPNNASDGNKAKPNAVVESSNNGNIDVDVDLGDGGVGKCEEQALVKDTGSEMENSATEMDTKGSLKEVINAAATTDVREAPTVAEAKTTTATVKTDASPTTTTTTTDFTPTTQQSAVSTLFPTFDFDLDFIGNVAHATTLKNNNDDSFNVASLPPPLLLNGSDKLLTAALEPSPVKDLRPRLPRTPIYVCKQCNQTFDELPKLLQHELQQHSSGTKSSLRSSYQHQCKICNASYRTVTLLNYHMKQHAPVKVPCKEFQVSTEVDPDHVQSDHRGNSGPLKCGIDGCRKTFNYKHHLKRHQTASHTPVQYICPKCGRDMLTSLYLRNHMSMHRGTHSYKCPKCVRTYMRRNPFRRHALREHKWELTDAEIDKIYCENDSTPSIILRDVR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00557462;
90% Identity
iTF_00518733;
80% Identity
-