Dkam000563.2
Basic Information
- Insect
- Drosophila kambysellisi
- Gene Symbol
- -
- Assembly
- GCA_035042185.1
- Location
- JAWNLS010000039.1:1564485-1569547[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0063 0.44 11.2 1.9 2 23 145 166 144 166 0.97 2 13 6.2e-06 0.00043 20.6 0.6 1 23 406 428 406 428 0.99 3 13 3.3 2.3e+02 2.6 0.8 1 23 434 457 434 457 0.92 4 13 5.6 3.9e+02 1.9 0.4 1 23 486 509 486 509 0.90 5 13 0.01 0.72 10.5 2.4 5 23 778 796 775 796 0.91 6 13 0.049 3.4 8.4 1.4 1 23 802 825 802 825 0.98 7 13 7.3 5.1e+02 1.5 1.0 2 19 865 883 861 885 0.55 8 13 0.0031 0.22 12.1 0.7 1 23 905 928 905 928 0.97 9 13 0.012 0.81 10.3 0.4 1 23 1144 1167 1144 1167 0.92 10 13 0.00034 0.024 15.1 3.0 1 23 1181 1203 1181 1203 0.98 11 13 0.0016 0.11 13.0 4.0 2 23 1235 1259 1234 1259 0.90 12 13 0.017 1.2 9.8 0.1 1 23 1264 1286 1264 1286 0.98 13 13 0.0064 0.45 11.1 1.3 1 23 1292 1315 1292 1315 0.96
Sequence Information
- Coding Sequence
- ATGGCGCACAAACGTTTGAAAGCAGCGGACATGGAAATCAATTACAAATTCGCATGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTCAAGCTGGACTCCCTCATCGACTGTAGCAACGATGATGCCAgtgacaatgacaatgatgCCGCGTCCCCCAAAAAATTGCCCTTGTTGCGTTTACTGCTCTTCTGCATGCGCACCGAAAATCTGCCCGAGCTGCCGCAATACATTTGCGTGGAATGCCGAAAAAGTTTACAAATTGCCTACTATTTCATACAGAACGGTTTGCGTGCACACGAAATATTGTGTCGCAAACTGTGTCCCGGCAAGCTGCAAACCAGATCGCGCATCAACGGACAACACTTAGCCCTAAGGAGCGAGGCAAAAGCTGGTACAGCGTCGCTTGACACGCACAGGGAGAGTcccataaaatgcaaaatatgcgGTGAGATTATCCACAATCGCTTAGAGCTCAATCATCATCTCCGAATGCATTCAGAGTACCGACAACAGtgtaaattgtgcaattttgtAACGCATAAGCATCGCCCGCTGCTGGAGCACTATCGCAAATCGCATGGCTTGACCACGGCCCAAATTGAGAACCAGCTGAAAATACGAAGATCGGTGCAAGCGGCTgctacaacatcaacaaaagcGACAGCATCTGCAACCACAGAaacgcctgctgctgctgctgcggatgaTGATGGTCAGGTGAAGGTGTGCACAATGGAGGACATGGAGCTGCTGATACCCACAGTGCTAACGCCCGAGGATTTCACGCATCCACAACTGTATGCGGATCAAGTGCGTGACATTGAACAGCAATTGACGAGCAGCTCGCTGAGAGTGGCCAACACCACAGCTACATGCACGGAACCAGTGACGGAAAATGCCAGCGGAAGCAGTGCTAACATGAGCATAGGTGCGGAGTTTTTGGTCATGCCTGACGGCTCGTTGCAGCAGGTGAATGATGGTGGCGTTGTCTTCGAATACATTGATGATAGTAAAAGTGCGGccggcacaacaacaacaacaatcacatcGACCAATGTGACTCTGGAGAGCCTGTTGAGTGACTCGAAAACCGATCTAACCTATGATGCAATGGAAATTGATCTGAGTCATATGGCTGTCGATAATGCGCTGCCACAGATAACAGTTAAGCCCAAGACGCGACCAGCGCCAGCGTCAAGTGGTTTCctgaaatacaaatgcaaagtaTGCCCCAAAGCATTTCCGACGGTGTCACGCCTCAAATCTCACCAGCTAACGCATAGCCATTTACCTAAGTTCTATTGCGATCAGTGCACATATTATTCGCTGCGCAGCGCCGATCTCATCCAGCATTATACGAGCGAGCATAATATATGCATTAGCGATACGAAAGCTAGTCAAGTGGAGAAGTCACCAATGATGTCGACAATGTTAACGGATCGCAATCGCATCTTCTCATGCGATATGTGTCTGTTTGAGACGCCGAGCGGCGGTCAGCTCCGCTCGCATTACAGTGATAAGCATCTCATTGTCCCCAGTGAGATACAGCTGCGTCCCAGCTGGATCAGGGATCAGCAGGATGACAATGCGAAGCTGAAAAGTGGCGACGGAAACACACAACCAGACATTCCGCTGGGCATTAAATATCCAACCATGACGCCGTGTGCAgtagccacaacaacaacgcaggcaataacaacaacggcagTGACTTCCACGGGTGGCATCAACGTTGTCGTGGATGCCAGCTCATTATTCTATGAGGAAACTTCTAACGAAAATAtagcaacaacggcagcagcgacaggtgcatcagcaacaacaacaacgggaaTAGATTCAAGTACAATTGCAATATTTCCTGAGCAATGCCAGTCAACAACTtcaaaggcagcaacaacaaatcaacagGAGGCTAGCAGCCAGGcagtgacaacaacagcagcaacaaatccCAATACTAGCACATTTGGCGATATGCAGGAGTTTATAGATAATACAGATGTGGCAGCTATATGCACAATACCCGCCGACGATATGCCTGTGGATGGCGATGATATCGTcatcgataataataatattagtcTGGATTTTGATGCTGAAAAGCTATTTGAGGAATTTGAAGATGTCGAAGTTGGCGAAGAagttgacgatgacgacgctGACGAGGatgacgaggatgaggatgaggacgaTGCGGAAAATGATGATGAGAATGATAACAATGATGCGGCTGCAGACCAAAATCTCTTACTGACAAgtgacgatgacgatgtggATGACTTTGACGACGAACAATCGAAGCATCTGCAGAAACCCTATTGCATcttttgcaataaaaagttTACCAGCCAATACAAGTTCGAGAATCACATGTTTCTGCATCGCGGCTTGGCACCCTATCGCTGTGAACTGTGCACCAATCTGTACAATATGAAACGCCTGCTCATACGACACTATAAAACAGTTCACAAAAAGATGCCCACGCGTGACATGGTGCAGGCCAAGGGCGACAAGGTAGCTGTGCCGTGTACGGCTATCgaaaagataaatataaatgcaggCAAAAatccTTTGTTGATGTGCGCCAAATGTCCCTTCGAATGCGAGCTGGATGTGGATATGCGCAAGCATTTAAATGCCCATCATGGCATCAACGATGGGGTTTCCATGCATGCCAACGAAGTGTTTATTATACGCAAACTGCCTTATGAGTGTCCACGCTGTATTCGTTCATTTGCGGCAAAGCGAACGTTGACACGCCACTTGCAGCGTAGCCATTTGGTGGATACAATCATTGAGATGCAGGCGCTGCAATTGACAACCAGTTCGGCAGCAACGACAaccacagcgacaacaacaaccacattgCCAAACAATGCCAGGGATGGCAGTAAAACCACTGCACATGCGGTTGAAGAGTCTGCCAACAATGGCAATGTCGATGCCGATCTTGGCGATGACGGCGATGGAAAATGCGAAGAGCAAGAGGTTGGCAAAGATGCAGTAtcagaaatgaaaaatttcGATACAGAAGTAGATATAAAAGGCACAATAAAAGAAGTTATAAATGCGGTAGCAACAACAGACGTAAGAGAAGCAACAACTGTACCAGAACCAACACCAAAAACACCTACAAAAGCAGAAGCTTgtgacacaacaacaaccacaacagattttacaccaacaacacaacaGTCTGCAGTCTCAACGCTTTTTCCAACGCCCACGCCTTTTGACTTTGATCTTGACTTCATTGGCAACGTGGAACATGCCACAACACTtaagaacaacaacgatgATAGCTTCAATGTGGCATCTCTGCCTCCGCCTCTACTGCTAAATGGCAGTGATAAGTTGCTGACTGCCGCACTGGAGCCGTCGCCCGTTAAGGATTTGCGAACACGTCTGCCCCGTACCCCCATCTATGTGTGCAAGCAATGCAATCAAACGTTCGATGAGCTGGCCAAGCTGTTGCAGCACGAGCTGCAACAACATTCCAGTGACACGACGTCCACGCCACGCAGCAGCCATCAGCATCAGTGCAAGATCTGTAATGCCTCCTATCGTACTGTGACCCTGCTCAATTATCACATGAAGCGACATACCCCGGTGAAAGTGCCCTGCAAGGAGTTTCAGGTTAGCACGGAGTTGGAACAACAAGTGCCGTCCGATCATCGTGGCAATAGCAGTCCACTCAAATGTGGCATCGATGGATGTAGGAAAACCTTCAATTACAAGCATCATTTGAAACGACATCAGACCGCATCGCATACTCCTGTGCAATACATTTGTCCGGTGTGCGGACGCGATTTGCTGACCAGTCTGTATCTGAGGAATCACATGTCCATGCACCGGGGCACCCACTCCTACAAGTGCCCCAAGTGCGTGCGCACCTATATGCGCCGTAATCCTTTCCGTCGACATGCGTTGCGGGAGCACAAATGGGAACTGACGGATGCagaaattgataaaatatattgtgAAAATGATTCAACGCCATCAATAATATTGCGCGATTTGCGGTGA
- Protein Sequence
- MAHKRLKAADMEINYKFACRCCLKSEAEFFKLDSLIDCSNDDASDNDNDAASPKKLPLLRLLLFCMRTENLPELPQYICVECRKSLQIAYYFIQNGLRAHEILCRKLCPGKLQTRSRINGQHLALRSEAKAGTASLDTHRESPIKCKICGEIIHNRLELNHHLRMHSEYRQQCKLCNFVTHKHRPLLEHYRKSHGLTTAQIENQLKIRRSVQAAATTSTKATASATTETPAAAAADDDGQVKVCTMEDMELLIPTVLTPEDFTHPQLYADQVRDIEQQLTSSSLRVANTTATCTEPVTENASGSSANMSIGAEFLVMPDGSLQQVNDGGVVFEYIDDSKSAAGTTTTTITSTNVTLESLLSDSKTDLTYDAMEIDLSHMAVDNALPQITVKPKTRPAPASSGFLKYKCKVCPKAFPTVSRLKSHQLTHSHLPKFYCDQCTYYSLRSADLIQHYTSEHNICISDTKASQVEKSPMMSTMLTDRNRIFSCDMCLFETPSGGQLRSHYSDKHLIVPSEIQLRPSWIRDQQDDNAKLKSGDGNTQPDIPLGIKYPTMTPCAVATTTTQAITTTAVTSTGGINVVVDASSLFYEETSNENIATTAAATGASATTTTGIDSSTIAIFPEQCQSTTSKAATTNQQEASSQAVTTTAATNPNTSTFGDMQEFIDNTDVAAICTIPADDMPVDGDDIVIDNNNISLDFDAEKLFEEFEDVEVGEEVDDDDADEDDEDEDEDDAENDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFLHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKKMPTRDMVQAKGDKVAVPCTAIEKININAGKNPLLMCAKCPFECELDVDMRKHLNAHHGINDGVSMHANEVFIIRKLPYECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQALQLTTSSAATTTTATTTTTLPNNARDGSKTTAHAVEESANNGNVDADLGDDGDGKCEEQEVGKDAVSEMKNFDTEVDIKGTIKEVINAVATTDVREATTVPEPTPKTPTKAEACDTTTTTTDFTPTTQQSAVSTLFPTPTPFDFDLDFIGNVEHATTLKNNNDDSFNVASLPPPLLLNGSDKLLTAALEPSPVKDLRTRLPRTPIYVCKQCNQTFDELAKLLQHELQQHSSDTTSTPRSSHQHQCKICNASYRTVTLLNYHMKRHTPVKVPCKEFQVSTELEQQVPSDHRGNSSPLKCGIDGCRKTFNYKHHLKRHQTASHTPVQYICPVCGRDLLTSLYLRNHMSMHRGTHSYKCPKCVRTYMRRNPFRRHALREHKWELTDAEIDKIYCENDSTPSIILRDLR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00557462;
- 90% Identity
- iTF_00522491;
- 80% Identity
- -