Basic Information

Gene Symbol
-
Assembly
GCA_035043035.1
Location
JAWNNG010000652.1:1079945-1084911[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00046 0.03 14.8 1.5 2 23 145 166 144 166 0.97
2 12 0.00014 0.0089 16.4 1.3 1 23 406 428 406 428 0.98
3 12 3.3 2.2e+02 2.6 0.8 1 23 434 457 434 457 0.92
4 12 9.8 6.4e+02 1.1 0.3 1 23 486 509 486 509 0.89
5 12 0.0042 0.28 11.7 2.1 5 23 791 809 788 809 0.92
6 12 0.6 39 5.0 3.2 1 23 815 838 815 838 0.98
7 12 0.0046 0.3 11.6 0.4 1 23 918 941 918 941 0.97
8 12 0.012 0.76 10.4 0.4 1 23 1118 1141 1118 1141 0.92
9 12 0.00034 0.022 15.2 3.0 1 23 1155 1177 1155 1177 0.98
10 12 0.0016 0.1 13.1 4.0 2 23 1209 1233 1208 1233 0.90
11 12 0.074 4.8 7.8 0.1 1 23 1238 1260 1238 1260 0.97
12 12 0.0044 0.29 11.7 1.4 1 23 1266 1289 1266 1289 0.97

Sequence Information

Coding Sequence
ATGGCGCACAAACGTTTGAAAGCAGCGGACATGgaaatcaattacaaattcGCATGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTCAAGCTGGACTCCCTCATCGACTGTGGCAACGATGATGCCAATGATAATGACAATGATGCCTCGTCCCCAACCAAATTGCCGCTTTTGCGTTTACTACTCTTCTGCATGCGCACCGAAAATCTGCCCGAGCTGCCGCAATACATTTGCGTGGATTGCCGCAAAAGTTTGCAAATTGCCTACTATTTCATACAAAACGGTTTGCGTGCCCACGATATATTGTGTCGCAAACTGTGTCCGGGCAAGCTGCAAACCAAACCGCGCATCAACGGACAACACTTAGCCCTAAGGATCGAGACAAAAGCTGGCGCAGCGTTGCTGGACACGGAGAGGGAGAAACCcctaaaatgcaaaatttgcgGTGAGATTATCCGCAATCGTCTGGAGCTCAAACATCATCTACGAAGGCATTCAGTGTCTCGACATCAGtgtaaattgtgcaattttgtGACGCTTAAGCATCGCCAGCTGCTGGAACACTATCGCAAATCGCATGGCTTGACAACGGCCCAAATTGAGCATCAGTTGAAATTACGAAAATCGCTGCAGGCGGCTGccagtgcaacaacaacaagaaaagcgaCAGCAGCTTTATCCACAGAAGCGCCAGCTGTTGCGGATGATGACGGTCAAGTGAAGGTGTGCACAATGGAGGACATGGAGCTGCTGATACCCACAGTGTTGAGGCCCGAGGATTTCACGTACCCACAACTGGATGCGGATCAATTGCGTGACATTGAACAGCAATTGACGAGTAGCTCGCTGGGATTGTCCAATCCCACAGCTGTATTCACGAAACCAGCGACGGCAAATGTCAGCGGAAGCAGTGCCAATATGAGCATAGGTGCGGAGTTTCTGGTCTTGCCGGATGGCACGTTGCAGCAGGTGAATGATGCTGGCGTTGTCTTCGAATATATTGATGATAGTAAAAATACGGCCAgcacagtaacagcaacaaccacatcgACCAATGTGACGCTGGAGAGCCTGTTGAGTGACTCGAAAACCAATTTAACCCATGATGCAATGGCCATTAATTTGAGTCACATGGCTGTCGATAATGCGCTGCCACAGATAACAGTCAAGCCCAAGGCGCGACCAGTGCCAGCATCAACTGGTGCCCtgaaacacaaatgcaaactgtGCCCCAAAGCATTTCCGACGGTGGCACGCCTGAAATCTCACCAGCTAACGCATAGCCATTTACCCAAATTCTATTGTGATCAGTGCACATATTATTCGCTGCGCAGCGCCGATCTCATCCAGCATTATACGAGCGAGCATAATGTATGCGTTAGCGATACGAAAGCTAGTCAAGTGGAAAAGACACCAATGCTGACGACAATGTTAACGGATCGCAATCGCATCTTCTCCTGCGATATGTGTCTGTTTGAGACGCCGAGCGGCGCTCAGCTGCGCTTGCATTACAGTGATAAGCATCTCTTTGTGCCTAGTGAGATACAGCTGCGTCCCAGCTGGATCAGGGATCAGCAGGATGGCAATGCGAAACTGAAAAGTGGCAACGGCAGCACAACACCAGACATTCCTCTGGGCATTAAATATCCAACCGTGACGCAGtgtgcaacagccacaacggcggcgacaacaacaagcaaggAGCTACAGCcgcaagcaataaaaacaacaacaacggctgTGACTTCGAAGGGTGGCATCAATGTCGTCGTGGATGCCAGCTCTTTATTctatgcagcaactgctgccgaAAATGTAGCACCAACTGGTggaacagaaacaacaacaacgggcgCAATGTCAACGGATTCAAGCACAATTGCAATATTTCCAGAGCAATGcctgtcaacaacaacaaccatagcaaaggcagcaacagcaaatcaaCAGGAAGCAAGCAGTcaggcagtggcaacaacaacagcaacaaatcccAATACTAGCACGTTTGGTGATATGCAGGAGTTTATAGATAATACAGATGTGGCAGCTATATGCACAATACCTGCCGACGATATGCCTGTGGATGGTGATGATATCGTcatcgataataataatattagtcTGGATTTTGATGCTGAAAATCTATTTGAGGAATTTGAAGATGTCGAAGTTGGCGAAGAGGTTGACGATGTCGACGCTGACGAGgatgacgaggatgaggatgaggatgatgcggataatgatgatgagaaTGATAACAATGATGCGGCTGCCGATCAAAATCTATTGCTAACcagcgacgatgacgatgtgGATGACTTTGACGACGAACAATCGAAGCATCTGCAGAAACCctattgcatattttgcaacaaaaagtttACCAGCCAATACAAGTTCGAGAATCACATGTTTGTGCATCGCGGTTTGGCACCATATCGCTGTGAGCTGTGCACCAATCTGTACCATATGAAACGCCTGCTCATACGACACTATAAAACAGTTCACAAAAAGATGCCCACGCGGGACATGGTGCAGGCCAAGGGCGACAAGGTAGACGTGCCGTGTGCGGCTATcgaaaagataaatataaatgcggGCAAAAatcCCTTGCTGATGTGCGCCAAGTGCCCCTTTGAAGGTGAGCTGGATGTGGATATGCgcaagcatttaaatgcacatcATGGCATCAACGATGGTGTTTCCATGCATGCCAACGAAGTGTTTATCATACGCAAACTGCCTTATGAGTGTCCACGCTGTATTCGTTCATTTGCGGCAAAGCGAACGTTGATACGCCATTTGCAGCGTAGCCATTTGGTGGATACAATCATTGAGATGCAGGCACTGCAATTGACAACTAGTTCGTCGGCAACGACAACcacagcgacgacaacaaccacattaCCTAACAATGCCATCGATGGCAGTACAGCCACAGCACATGCGGATGAGGAGTCTTGCAACAAGAGCAGTATCGATGTCGATCTTGGCGATGGCGGCGATAGAAAATGCGGATCAGAAATGGAAAATTCCGATACAGAAGTGGATATAAAAGGCGCAATAAAAGAAGTtacaacaaaaagcacaacagATTTTACACCAACAACGCAACAGTCAGCAGTCTCATCGCTTTTTCCAACGCCCACGCCTTTTGACTTTGATCTCGACTTCATTGGCAACGTGGCAGACGCTACAACGctgaagaacaacaacgatgatAGCTTCAATGTGGCATCTCTGCTTCCGCCTTTACTGCTAAATGGCAGCGATAAGTTGCTGGCTGCCGCTCTGGAGCCGTCGCCCGTTAAGGATTTGCGTCCACGTCTTCCCCGTACCCCCATCTATGTGTGCAAGCAATGCAATCAAACGTTCGACGAGCTGGCAAAACTGTTGCAGCACGAGCTGCAGCAACATTCCAGTGGCACGAAGTCCACGCCACTCAGTAGCTATCAGCATCAGTGCAAGATCTGTAATGCCTCCTATCGCACTGTTACCCTCCTCAATTATCACATGAAGCGACATGCGCCGGACAAAGTGCCCTGCAAGGAGTTTCAGGTTAGCACGGAGTTGGAGCAACATGTTCCGTCCGATCATCGTGGCAATAGTGGTCCACTCAAATGTGGCATCGATGGGTGTAGGAAAACCTTCAATTACAAGCATCATTTGAAGCGACATCAGACCGCATCGCATACGcctgtgaaatatatttgttcgGTGTGCGGACGAGATTTGCTGACCAGTCTGCTTCTGAGGAATCACATGTCCATACACCGGGGCACCCACTCCTACAAGTGCCCCAAGTGCGTGCGCACCTATATGCGCCGTAATCCTTTCCGTCGACATGCGATGCGGGAACACAAATGGGAGTTGACGGATGCggaaattgataaaatatattgtgAAAATGATTCAACGCCATCAATAGTATTGCGCGATTTGCGGTGA
Protein Sequence
MAHKRLKAADMEINYKFACRCCLKSEAEFFKLDSLIDCGNDDANDNDNDASSPTKLPLLRLLLFCMRTENLPELPQYICVDCRKSLQIAYYFIQNGLRAHDILCRKLCPGKLQTKPRINGQHLALRIETKAGAALLDTEREKPLKCKICGEIIRNRLELKHHLRRHSVSRHQCKLCNFVTLKHRQLLEHYRKSHGLTTAQIEHQLKLRKSLQAAASATTTRKATAALSTEAPAVADDDGQVKVCTMEDMELLIPTVLRPEDFTYPQLDADQLRDIEQQLTSSSLGLSNPTAVFTKPATANVSGSSANMSIGAEFLVLPDGTLQQVNDAGVVFEYIDDSKNTASTVTATTTSTNVTLESLLSDSKTNLTHDAMAINLSHMAVDNALPQITVKPKARPVPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCTYYSLRSADLIQHYTSEHNVCVSDTKASQVEKTPMLTTMLTDRNRIFSCDMCLFETPSGAQLRLHYSDKHLFVPSEIQLRPSWIRDQQDGNAKLKSGNGSTTPDIPLGIKYPTVTQCATATTAATTTSKELQPQAIKTTTTAVTSKGGINVVVDASSLFYAATAAENVAPTGGTETTTTGAMSTDSSTIAIFPEQCLSTTTTIAKAATANQQEASSQAVATTTATNPNTSTFGDMQEFIDNTDVAAICTIPADDMPVDGDDIVIDNNNISLDFDAENLFEEFEDVEVGEEVDDVDADEDDEDEDEDDADNDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYHMKRLLIRHYKTVHKKMPTRDMVQAKGDKVDVPCAAIEKININAGKNPLLMCAKCPFEGELDVDMRKHLNAHHGINDGVSMHANEVFIIRKLPYECPRCIRSFAAKRTLIRHLQRSHLVDTIIEMQALQLTTSSSATTTTATTTTTLPNNAIDGSTATAHADEESCNKSSIDVDLGDGGDRKCGSEMENSDTEVDIKGAIKEVTTKSTTDFTPTTQQSAVSSLFPTPTPFDFDLDFIGNVADATTLKNNNDDSFNVASLLPPLLLNGSDKLLAAALEPSPVKDLRPRLPRTPIYVCKQCNQTFDELAKLLQHELQQHSSGTKSTPLSSYQHQCKICNASYRTVTLLNYHMKRHAPDKVPCKEFQVSTELEQHVPSDHRGNSGPLKCGIDGCRKTFNYKHHLKRHQTASHTPVKYICSVCGRDLLTSLLLRNHMSIHRGTHSYKCPKCVRTYMRRNPFRRHAMREHKWELTDAEIDKIYCENDSTPSIVLRDLR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00557462;
90% Identity
iTF_00496942;
80% Identity
-