Doch000891.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ochracea
Gene Symbol
-
Assembly
GCA_035044125.1
Location
JAWNML010000003.1:7239425-7245980[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.051 3.2 8.3 0.2 1 23 1381 1404 1381 1404 0.94
2 13 4.6 2.9e+02 2.1 0.2 1 23 1574 1596 1574 1596 0.91
3 13 0.00018 0.012 16.0 2.7 2 23 1599 1620 1599 1620 0.97
4 13 7.1e-05 0.0045 17.3 0.2 3 23 1628 1648 1626 1648 0.98
5 13 5.9e-07 3.7e-05 23.8 4.1 2 23 1655 1676 1654 1676 0.97
6 13 5.6 3.5e+02 1.9 0.4 5 23 1689 1707 1687 1707 0.96
7 13 1.4 88 3.8 5.4 3 23 1714 1735 1712 1735 0.93
8 13 0.15 9.4 6.8 0.2 2 23 1746 1766 1745 1766 0.96
9 13 5.7e-05 0.0036 17.6 0.4 1 19 1772 1790 1772 1794 0.95
10 13 1.6e-05 0.001 19.3 0.5 1 23 1802 1824 1802 1824 0.98
11 13 0.00011 0.0067 16.7 7.6 1 23 1830 1852 1830 1853 0.96
12 13 0.00021 0.013 15.8 5.9 1 23 1858 1880 1858 1880 0.98
13 13 0.029 1.9 9.0 8.2 1 23 1886 1908 1886 1909 0.95

Sequence Information

Coding Sequence
atggtGGACAGTGTGCAGTGCCCCGTGTGCACCTTGTATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCattgctggcaacaacaatggtggTCTGGACAGCGCCCTGGCGGCAGCTGTCATCTCCAGCAGCAGTCGCTGCAGCGTTGCCTCAACCGAAAGCGTCGCCTCAACGCCGCCTGCTGTTGGTGTCAAACCGGATGTGGCATCAGTaccaacagcggcagcaacacaaCCGCCACAGCCACCACAACCAccccaaccaccaccaccagcagcagcaacaacaacagcaggagcagtagcatcaacaacaagcacatcGCAATCAACAACACCCAAGGCTGTCGCATTGCTGgacaacgccagcagcagcagtagcaacaacagcagcagcagcaacaacaacaacaacaacaacaacaaattgagcaATCCACCGACTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCATAAGCAACGTGTCTGCTGTCTATCCGGCAACCCTGGCAACCGACTATCGCtacgaacagcagcaacagccacagctacagcagcagcaccagcagctgcatGGCTTTCCACGTGGCACCACCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAGCCAACAGCCGCCTGCGCACTTTgcccaccagcaacagcagccgcagtcgaCCATGAAGTTCACgtatgcaacagcagcgttgCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAGCCGACGGCAACGCCGCCGCATCAGAAGCCTCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCATAaccaaaacaagcaacaacaccaacaccaccaacaacaacaacagcaaccacaacacaTAAGCGTACAGCAGcataatgcaaatgcagcaccACCGagtggcaaacaacaacacaatggCAAAATCCATGCGGATATCTTTCTGAatccaccaccaccgccacagCTCACAATTCCatcgtcggcgtcggcgtcttcgttgtcgttgtcgctgtcgacCTCCTCAAGACTGCAACATCCccaacagcaccaccaacaatCCCATGCggctagcagcagcagcagtagcaacagcaactatgcAGCAACCAGCTGCGCTCCCAGCTCCTCGGTTGCTCAGATGTCCGGCACATCGTCGGCACGCGCCAGCAGTCGCCAGTCGAGCAATTCACCCTTTGGTGCCCTGCTGAATGCGGCTGCGCACGCTGCTTGCTCCTCGCCCGCTTCGACTGGGGCGTCTGTGCTGCGCTATGCCGAGTCGCCAGTGGCCCACTATCTGGAGCGGGATAACGGTGATTTCATAGTGCAGGAGACGCCCAAGCACATTGTGGAGTGTGTCGAGAAAGACGACGGCGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTCCACAtacacgacgacgacgaagaggaggaggaggacgaggaTGATCAGCAGGGttgGGCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGCCGAGTTGCACCCAAAACGACAACGAAAAAGTCACGCAAGACTAAATCGAGTGGCAGATTGCACAAGCGCGCCTCCAAGCATCAGCTGGCCACGACGACGGAGGACGAGGACGACTTCATGAGCATAGGCAGCAGTTGTGCCGAAAGCGATCATCATCCagaggagcagctgcagcaacagcagccgcaattAGCATCGGCTGGGGGGGCAGCACAGTTGGCGGCGAGCTCATCGCCGGTTCAACTTTGCACTGCGCCCTCCACGAGCAgtggagctgctgttgctgctactgcagccGCTGCCGCCACTGGTGGTAAATTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGACTCGCATTGGTGCAGCGCGTCCCTTTGCGGCTGTGGCGCCCATACCGCTCGTCAAAGTGGAAAAGGAGGAACCCATGGATGAATATGATGCCATTGAGGTCGAGATGCAGTTGGAGCAAAAGCCCAGCCTAGAGCATgctagcggcagcagcagtagcagcagcagtagcagcaacagtagcagcagcagcagcagcagtggacATGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGCGGCGAACGTGGCTGCCGAGGATCTCACACAGCCGCCGCCGATGAAGGTGGAGGTAGAGCCAACGGCGCTGCTGCCGCAACGCTTCTCGGCACCCGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCacagcgacggcaacggcgacgtCAACGACGAAAAAGACTGAGAacaacgctgctgctgttgctactggcagcaacagtagcaattGCGCCGAATCCCATAGCATATCAGTGAATACGCCCGCCGAGCTTGTGCAGATCAAGAGCGAAAACGTGGAGGCGTCCACATCGAGCAGTAGCAGCATATTGGAAAAGCATCTGACTACCAGCTATGCGGCACAGCAGGCGGCACGCAAGCACTCCGCCGTCAACGATGACGATGCACGTGTGCTGCTCGAGTTTGCCAACTCGAAGCAGCTGCCGATGCCGGGCAACAGCAATCATACCACGTTTGTGGTGAACGCGGCCAGTTTTGCGTCAGCGGGTTCCGTATTtgccagtggcagcagcagcagcggtgtcAATGTGCAAAAGTCAACCAAGTCGGGCTGTGGCGATGAGTACATTCTGCCCGATGACACCAAGCTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCAcctcgcagcagcaacagcagcatctccaacaacaaacacaacagcagcagcagcaacaacaacaatctttGCAGCAGGCGCAACCATCCGCCTTCACTGAGTTTAGTTTTCTGTACcaccaaaacacaacaacaacaacagcagctgcagcagcagcggcagcggcaacaacggcGACATCTACTACTTCCAACTTTGCACCGTTTGGcattcagcaacagcaacaacagttgcagttgcaacatcATCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCAACGCTTGCATCCTCGTCGAGCAATTCGTCTGCATTGGATCAGGAGTGCTCGATGAATGCCACGTTTCGCGTGGCAAAGCCACAATCAATGCTGGGCACCTGGTATCAGCCACATCAGGCGCAGCATCAAGTGACATCTTCGCACAGTCCACAACATGTGGATCAGCCGAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTGGATAGCGATATGAGCGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACAgctgagcaacagcagcagccatatGCCATCCGCTTCGACATCGACCACATCGTCAtcgtttgctgctgcagcaacggAGAGCAGTCTCGTCGGTGGCCTGGGTCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAACAGGAAAGCAACTGCGACATAGAGAACTCTTGGAGTCAATCGatGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCACGACTATTATCCGGCGCAGGATCTCAgtggtcagcagcagcagcagcgagagcAAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCACAGCCGGGCGAGCTGGAAGCTTCCTCGAGCTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGCGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCTCAACGGAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACATTGTGTGGCCATCTTCGAGAAGCTAAAGGAGCGCAATGCGCACATGATTGGCGAGCACAACTATGTGCGCCAGAATCGGCGTCTCATTTGCACGCAGGCGCTGGTCAGCGCTGCGATGCTCGCCCAGCCGCTGGCTCAGCAGTCAGAGCAGCAAATGGAGctggaacagcagcaacagcatcagttGCTGCAGGTGAGCCACAGCACGGGCGGCGCCGAGCACGAGGATTCCAAGGATGGTATTGTGAAGATTAAGCAGGAACATTGTCACGACAAGCACGATCCAACATCGGAGCAATTGCTTGGCCACTTGGAGCTGCCAGATGTGAAGGATGCTGGCCTGCTCGAAACCAGTGGTGAAAACGGACGCGATGCGGACATGAAGCCACCAGCCACTGTTGCTGAGCTTGACGAGAAACCGACCATAGCACCGCTGGCCATGACGACGCCCGCTGCTAAACTGGCTGCTCTTTATCGCATGCTAATTGCCTACAACGAATCGAAGCTGGGCCAGGAGCGCAACAATCTAAGCGAACTGGAGCAAAAGGCAATGGAGAAATCTATATTCTTGTGCTACATTTGCCGCACCGATTTCCCCTCTGTGAAACTGTACGATGCGCATCTAACCGAGCATCCCGCCGAGTGTTTCACTTGCGGCAAGAAATTCTATCGCTGGAAGAACTTCTCGCTGCACCTGAAACGCCATCTGGGCTGGAAGGAGTTTGGCTGCTATGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCTCTCGTCGAGCACATGCGGATGCACACTGGCCAGACGCCACTCAAGTGCAAGATATGTGGCAAGAAGTTCAAGCGATACTCGAATTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTGTGCCACTGCGGCGAAGTGCTGCCCTCAAAGGCCCGCTTCCTGTGGCACAAAGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCGAACTCGCTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTCGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCGAAGACATCGATTAAGGCGCACATGGCGACGCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGAACGGCCAAACCGTTCAAGTGCGAGTACTGCCCGAAGGCATTTGTGCGCGAGTTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGCAACAAGAAGTTCACGTGCGATCAATGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGACGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAACATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNNGGLDSALAAAVISSSSRCSVASTESVASTPPAVGVKPDVASVPTAAATQPPQPPQPPQPPPPAAATTTAGAVASTTSTSQSTTPKAVALLDNASSSSSNNSSSSNNNNNNNNKLSNPPTKAVKSAPPTTEAPATTSNNNTPTISNVSAVYPATLATDYRYEQQQQPQLQQQHQQLHGFPRGTTTTLVIPQAPPQQHHNFLASQQPPAHFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTATPPHQKPPPAYGAAISQIRSQHNQNKQQHQHHQQQQQQPQHISVQQHNANAAPPSGKQQHNGKIHADIFLNPPPPPQLTIPSSASASSLSLSLSTSSRLQHPQQHHQQSHAASSSSSSNSNYAATSCAPSSSVAQMSGTSSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEDEDDQQGWANSDEEDHVKVPHEHVEDGDDEHEDSRSRVAPKTTTKKSRKTKSSGRLHKRASKHQLATTTEDEDDFMSIGSSCAESDHHPEEQLQQQQPQLASAGGAAQLAASSSPVQLCTAPSTSSGAAVAATAAAAATGGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASTRIGAARPFAAVAPIPLVKVEKEEPMDEYDAIEVEMQLEQKPSLEHASGSSSSSSSSSNSSSSSSSSGHGTTSVIRMASTSAANVAAEDLTQPPPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATATSTTKKTENNAAAVATGSNSSNCAESHSISVNTPAELVQIKSENVEASTSSSSSILEKHLTTSYAAQQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGSSSSGVNVQKSTKSGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQHLQQQTQQQQQQQQQSLQQAQPSAFTEFSFLYHQNTTTTTAAAAAAAAATTATSTTSNFAPFGIQQQQQQLQLQHHPQHGSSEATNAATLASSSSNSSALDQECSMNATFRVAKPQSMLGTWYQPHQAQHQVTSSHSPQHVDQPSNFIAALSAVDCCSAAVDSDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQREQKRFDFNAVASEYAQPGELEASSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVSAAMLAQPLAQQSEQQMELEQQQQHQLLQVSHSTGGAEHEDSKDGIVKIKQEHCHDKHDPTSEQLLGHLELPDVKDAGLLETSGENGRDADMKPPATVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV