Dinf015515.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila infuscata
Gene Symbol
-
Assembly
GCA_035042205.1
Location
JAWNLR010000765.1:26740-33167[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.052 3.7 8.3 0.2 1 23 1371 1394 1371 1394 0.94
2 13 4.7 3.4e+02 2.1 0.2 1 23 1564 1586 1564 1586 0.91
3 13 0.00019 0.014 16.0 2.7 2 23 1589 1610 1589 1610 0.97
4 13 7.2e-05 0.0052 17.3 0.2 3 23 1618 1638 1616 1638 0.98
5 13 6e-07 4.3e-05 23.8 4.1 2 23 1645 1666 1644 1666 0.97
6 13 5.7 4.1e+02 1.9 0.4 5 23 1679 1697 1677 1697 0.96
7 13 1.4 1e+02 3.8 5.4 3 23 1704 1725 1702 1725 0.93
8 13 0.15 11 6.8 0.2 2 23 1736 1756 1735 1756 0.96
9 13 5.7e-05 0.0042 17.6 0.4 1 19 1762 1780 1762 1784 0.95
10 13 1.6e-05 0.0012 19.3 0.5 1 23 1792 1814 1792 1814 0.98
11 13 0.00011 0.0078 16.7 7.6 1 23 1820 1842 1820 1843 0.96
12 13 0.00021 0.015 15.8 5.9 1 23 1848 1870 1848 1870 0.98
13 13 0.03 2.1 9.1 8.2 1 23 1876 1898 1876 1899 0.95

Sequence Information

Coding Sequence
atggtGGACAGTGTGCAGTGCCCCGTGTGCACCTTATATCTGCATGCGGGAATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCATTGCTGGCAACAATGGTGGTCTGGACAGCGCCCTGGCGGCAGCTGTCATCtccagcagcagtcgcagcagcgtTGCCTCAACCGAAAGTGTCGCCTCAACGCCGCTTGCTGTTGATATCAAACCAGATGTGGCATCAGTAccaacagcgacggcaacacaaccaccacagccacaacaaccGCCCCAACTACCACCAccactagcaacaacaacagcagcaacatcaacaacaagcacaTCGCAATCAACAGCACCCAAAGCTGTCGCATTGCTGGAacacgccagcagcagcagtaacaacaacagcagcaataataacagcagcagcaacaacagcagcaacaacaaattgagcAATCCACCGATTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCACatccaacaacaaaacacccACCATGAGCAGCGTGGCTGCTGTCTATCCGGCAACCCTGGCAACGGATTATCCCtacgaacagcagcaacagacacagcaacagcagcagccgctgcatgGCTTTCCACGGGGCACCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAACCAACAGCCGCCTGCGCACTTTGcccatcagcaacagcagccgcagtcaACCATGAAGTTTACgtatgcaacagcagcgttGCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAATCGACGGCAACGCAGCCGCATCAGAAGCCCCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGcataaccaaaacaaacaacaacaccaacaccaccaacaacagcaacaacaacacataaaCGTACAGCAGCataatgcaaatgcagcacCACCGAGTggcaagcaacaacacaacagcaaaatcCATGCGGATATCTTTCTGAATCCACCGCCACCCCCACAGCTCACAATTCCatcgtcggcgtcggcgtcatcgttgtcgttgtcgctgtcCCTGTCGTCATCGAACTCCTCAAGACTGCAACATCcgcaacagcaccaacaacaatccCATGCttctagcagcagcagcaactatgCAGCCACCAGCTGCGCTCCCAGCTCCTCGGTTGCTCTGATGTCCGGCACATCGTCGGCACGCGCCAGCAGTCGCCAGTCGAGCAATTCGCCCTTTGGTGCCCTGCTGAATGCGGCAGCGCACGCTGCCTGCTCCTCGCCCGCTTCGACTGGGGCGTCTGTGCTGCGCTATGCCGAGTCGCCAGTGGCCCACTATCTGGAGCGAGAGAACGGTGATTTCATAGTGCAGGAAACACCCAAGCACATTGTGGAGTGTGTCGAGAAAGACGACGGTGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCCCCCAGCGTTCTCCACAtacacgacgacgacgaagaggaggaggaggacgcGGATGATCAGCAAGGTTGGGCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGCCGAGTTGCACCCAAAACGACAACGAAAAAGTCACGCAAGACAAAAACAAGTAGCAGACTGCACAAGCGCGCCTCCAAGCCTCAGCTGGCTACGACGACGGAGGACGAAGATGACTTCATGAGCATAGGCAGCAGCTGTGCCGAAAGCGAGCATCATcccgaggagcagcagcaacaacagcaacagcagcagcatccgcaGCAGTTATCGTCGGCTGTGGGGGCAGGACAATTGGCGGTGAGCACTTCTCCAGCTCCTCAACTTTGCACTGCGCCCTCTACGAGCGgtggagctgctgttgctgctgttgctgctgtagctgccGCCAGCGGTGGTAAATTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGTGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGAGTCGCATTGGCGCAGCGCGTCCCTTTGCCGCTGTGGCTCCCATACCGCTCGTCAAGGTGGAAAAGGAGGAACCCATGGATGAATATGATGCCGTTGAGGTCGAGATGCAGTTGGAGCAAAAGCCCAGCCTTGAGCAtgccagcggcagcagcagcagcagcagtagtagcagcaatagtagcagcagcagcagcagcagtggacaTGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGCGGCGAACATTGCCGCCGAGGATCTCACACAGCCGCCGCCAATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTTCCGCAACGCTTCTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCacagcgacggcgacgtcaACGATGAAAAAGACTGAGAacaacgctgctgctgttgctaatggcagcaacagtagcaattGCCCCGAATCCCACACCATATCAGTGAATACGCCCGCCGAGCTGGTGCAGATCAAGAGCGAGAACGTGGAGGCGTCCACAtccagcagtggcagcataTTGGAAAAGCATCTGACTACCAGCTATGCGGCACAGCAGGCGGCCCGCAAACACTCGGCCGTCAACGATGACGATGCACGTGTCCTGCTCGAGTTTGCCAACTCGAAGCAGCTGCCGATGCCGGGCAATAGCAATCATACTACGTTTGTGGTTAACGCGGCCAGTTTTGCGTCTGCGGGTTCCGTATttgccagcggcagcagcagcagcggtgtCAATGTGCAAAAGTCAACCAAGCCGGGCTGTGGCGAAGAGTACATTCTGCCCGATGACACCAAACTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCAcctcgcagcagcagcatcttcaacaaacacaaacacaacagcagcagcaacaacaatcttTGCAGCAGGCGCAACCATCCGCCTTCACTGAATTTAGTTTTCTGTACcaccaaaacacaacaacaactccagcagcaacaacggcgaCACCTATTGCTTCCAACTTTGCACCGTTTGgcattcagcagcagcaacagcaaccacagttgcagttgcaacatcaTCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCAACGCTTGCATCCTCGTCGAGCAATTCGTCTGCATTGGACCAGGAGTGCTCGATGAATGCCACGTTTCGCGTGGCAAAGCCACAATCAATGCAGGGCGTCTGGTATCAGCCACATCAGGCGCAGAATCAGGTAACGTCTTCGCACAGTCCACAACATGTGGATCAGCCGACCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGATAGCGATATGAGTGAGGCCAAATATTTGGATCTGGATGCCTGCAAGCGGGAACAgctgagcaacagcagcagccatatGCCCTCCGCTTCGACATCGACCACATCGTCATCGTTTGCTGCCGCAGCAACGGAAAGCAGTCTTGTCGGTGGCCTGGGTCTAAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAGCAGGAAAGCAACTGCGATATTGAGAATTCTTGGAGTCAATCGATGTATGGCGACATATCACAGCGTTATTTTAGGAATCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCATGACTACTATCCGGCGCAGGATCTcagtggccagcagcagcagcagcgagagcaAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGTCCAGCCGAGCGAGCTGGAAGCTTCCTCAAGCTCAACGAGGACCAATCATTTGTTGGATACACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGTGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCGCAACGGAAGCCACCACGTCGCAAGATCTACAAGTGTCCACACTGTGTAGCCATTTTCGAGAAGCTGAAGGAGCGCAATGCGCACATGATTGGCGAGCACAACTATGTGCGCCAGAATCGCCGTCTCATCTGCACCCAGGCGCTGGTCAACGCTGCGATGCTGGCCCAGCCGCTGCCTCAGCAGccagagcagcagctggagctggagcagcagcaacagcatcagctgcTGCAGGTGAGCCACAGCACGGGCCGCGCCGAGCACGAAGACTCCAAGGATGGTATTGTGAAGATTAAGCAGGAACACTGTCAGGACAAGCACGATCCAGCATCGGAGCAATTGCTAGGCCACTTGGAGCTGGCAGATGTGAAGGATGCTGGCTTGCTCGATGCCAGCGGGGAAAACGGACGCGATGCAGACATGAAGCCACCAACCACTGTTGCTGAGCTGGACGAAAAACCGACCATAGCACCGCTGGCTATGACGACGCCCGCTGCGAAACTGGCTGCTCTTTATCGCATGCTGATTGCCTACAACGAATCGAAGCTGGGCCAGGAGCGTAATAATCTTAGCGAACTGGAGCAAAAGGCCATGGAGAAATCCATATTCTTGTGCTACATTTGCCGCACCGATTTTCCCTCTGTGAAGCTGTACGATGCGCATCTAACTGAGCATCCCGCCGAGTGTTTCACCTGCGGCAAGAAATTCTATCGCTGGAAGAACTTCTCGCTGCACCTGAAACGCCATCTGGGTTGGAAGGAGTTCGGCTGCTATGTCTGCGACAAAAAGTTTGTGGTGCGCAGCGCTCTCGTCGAGCACATGCGGATGCACACTGGCCAAACGCCACTGAAGTGCAAGATATGCGGCAAGAAATTCAAGCGATACTCGAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTGTGCCACTGTGGCGAAGTGTTGCCCTCAAAGGCGCGCTTCCTGTGGCACAAGGAGACGCACGACTTGAAACCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCAAACTCGTTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTCGACTATGCCGAACCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATAAAGGCGCACATGGCGACGCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCATGGGTGCATGCGAATCGCACGGCCAAACCGTTCAAGTGCGAGTACTGCCCCAAAGCGTTCGTGCGCGAGTTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGCTGCAAGTTCATACGCAAGTACAACTATATGCGGCATCGGCGGGAACATCATGGCAACAAGAAGTTCACGTGCGATCAGTGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAGCATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNGGLDSALAAAVISSSSRSSVASTESVASTPLAVDIKPDVASVPTATATQPPQPQQPPQLPPPLATTTAATSTTSTSQSTAPKAVALLEHASSSSNNNSSNNNSSSNNSSNNKLSNPPIKAVKSAPPTTEAPATTSNNKTPTMSSVAAVYPATLATDYPYEQQQQTQQQQQPLHGFPRGTTTLVIPQAPPQQHHNFLANQQPPAHFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQSTATQPHQKPPPAYGAAISQIRSQHNQNKQQHQHHQQQQQQHINVQQHNANAAPPSGKQQHNSKIHADIFLNPPPPPQLTIPSSASASSLSLSLSLSSSNSSRLQHPQQHQQQSHASSSSSNYAATSCAPSSSVALMSGTSSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEDADDQQGWANSDEEDHVKVPHEHVEDGDDEHEDSRSRVAPKTTTKKSRKTKTSSRLHKRASKPQLATTTEDEDDFMSIGSSCAESEHHPEEQQQQQQQQQHPQQLSSAVGAGQLAVSTSPAPQLCTAPSTSGGAAVAAVAAVAAASGGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPMDEYDAVEVEMQLEQKPSLEHASGSSSSSSSSSNSSSSSSSSGHGTTSVIRMASTSAANIAAEDLTQPPPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATSTMKKTENNAAAVANGSNSSNCPESHTISVNTPAELVQIKSENVEASTSSSGSILEKHLTTSYAAQQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGSSSSGVNVQKSTKPGCGEEYILPDDTKLEVDEIVISSSSSYASTSQQQHLQQTQTQQQQQQQSLQQAQPSAFTEFSFLYHQNTTTTPAATTATPIASNFAPFGIQQQQQQPQLQLQHHPQHGSSEATNAATLASSSSNSSALDQECSMNATFRVAKPQSMQGVWYQPHQAQNQVTSSHSPQHVDQPTNFIAALSAVDCCSAAVDSDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQREQKRFDFNAVASEYVQPSELEASSSSTRTNHLLDTQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPPRRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVNAAMLAQPLPQQPEQQLELEQQQQHQLLQVSHSTGRAEHEDSKDGIVKIKQEHCQDKHDPASEQLLGHLELADVKDAGLLDASGENGRDADMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
-