Dbas003346.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila basisetae
Gene Symbol
-
Assembly
GCA_035041595.1
Location
JAWNLB010000090.1:2713700-2721396[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.051 3.1 8.3 0.2 1 23 1395 1418 1395 1418 0.94
2 13 4.6 2.8e+02 2.1 0.2 1 23 1588 1610 1588 1610 0.91
3 13 0.00018 0.011 16.0 2.7 2 23 1613 1634 1613 1634 0.97
4 13 7.1e-05 0.0044 17.3 0.2 3 23 1642 1662 1640 1662 0.98
5 13 5.9e-07 3.6e-05 23.8 4.1 2 23 1669 1690 1668 1690 0.97
6 13 5.6 3.4e+02 1.9 0.4 5 23 1703 1721 1701 1721 0.96
7 13 1.4 85 3.8 5.4 3 23 1728 1749 1726 1749 0.93
8 13 0.15 9.1 6.8 0.2 2 23 1760 1780 1759 1780 0.96
9 13 5.7e-05 0.0035 17.6 0.4 1 19 1786 1804 1786 1808 0.95
10 13 1.6e-05 0.001 19.3 0.5 1 23 1816 1838 1816 1838 0.98
11 13 0.00011 0.0065 16.7 7.6 1 23 1844 1866 1844 1867 0.96
12 13 0.00021 0.013 15.8 5.9 1 23 1872 1894 1872 1894 0.98
13 13 0.029 1.8 9.0 8.2 1 23 1900 1922 1900 1923 0.95

Sequence Information

Coding Sequence
atggtgGACAGTGTGCAGTGCCCTGTGTGCACCTTATATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCattgctggcaacaacaatggtggTCTGGACAGCGCCCTGGCGGCAGCTGTCATCTCCAGCAGCAGTCGCTGCAGCGTTGCCTCAACCGAAAGCGTCGCCTCAACGCCGCCTGCTGTTGATATCAAACCGGATGTGGCATCAGTaccaacagcgacagcaacacaACCGCCACATCCACCACAACCACCCcaaccatcaccaccaccagcagcaacaacaacaacagcagcagcagcagcatcaacaacaacaagcacatcGCAATCAACAGCACCCAAGGCTGTCGCATTGCTGgacaacgccagcagcagtagcaacaacagcagcagcaacaacaacaacaaccacaacaaattgAGCAATCCACCGATTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCATAAGCAACGTGTCTGCTGTCTATCCGGCAAACCTGGCAACCGACTATCGCtacgaacagcagcaacagccacaggtacagcagcagcaccagcagctgcatgGCTTTCCACGTGGCATCACCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACAACAATTTTCTGGCCAACCAACAGCCGCCTGCGCACTTTgcccaccagcaacagcagccgcagtcgaCCATGAAGTTCACgtatgcaacagcagcgttgCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAGCCGACGGCAACGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCATAaccaaaacaagcaacaacaccaacaccaccaacaacaacaacaacaacagcaaccacaatcCATAACCGTACATCAGcataatgcaaatgcagcacCACCGagtggcaaacaacaacacaatagCAAAATCCATGCGGATATCTTTCTGAatccaccgccaccgccacagCTCACAATTCCATCGTCGGCCTCGGcgtcatcgttgtcgttgtcgctgtccCTGTCGTCATCGACCTCCTCAAGACTGCAACATCCccaacagcaccaccaacaatcTCATGCGgctagcagcagtagcagtagcagcagcaactatgcAGCAACCAGCTGCGCTCCCAGCTCCTCGGTTGCTCTGATGTCCGGCACATCGTCGGCACGTGCTAGCAGTCGCCAGTCGAGCAATTCACCCTTTGGTGCCTTGCTGAATGCGGCTGCGCACGCTGCCTGCTCCTCGCCCGCTTCGACTGGGGCGTCTGTGCTGCGATATGCCGAGTCGCCAGTGGCCCACTATCTGGAACGGGATAACGGTGATTTCATAGTGCAGGAGACGCCCAAGCACATTGTGGAATGTGTCGAGAAAGACGACGGTGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTCCACAtacacgacgacgacgaagaggAGGGGGAGGACGAGGATGATCAGCAGGGttgGCCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGCCGAGTTGCACCCAAAACGACAACGAAAAAGTCACGCAAGACAAAATCGAGTGGCAGATTGCACAAGCGCGCCTCCAAGCATCAGATGACCACGACCACGGAGGACGAGGATGACTTCATGAGCATAGGTAGCAGTTGTGCCGAAAGCGATCATCATCCagaggagcagctgcagcaacagcagccgcagcaacagcatccgcAGCAATTAGCACGCAATCCGCAGCAATTAGCATCCGCTGGGGGGGCAGCACAGTTGGCGGCAAGCTCATCGCCAGCTCAACTTTGCACTGCGCCCTCCACGAGCAgtggagctgctgttgctgctgccgccgccgtcgccAGTGGTGGTAAATTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGAGTCGCATTGGCGCAGCGCGTCCCTTTGCCGCTGTAGCGCCCATACCGCTCGTCAAGGTGGAAAAGGAGGAACCCATGGATGAATATGATGCCGTTGAGGTCGAGATGCAGTTGGAGCAAAAGCCCAGCCTAGAGCACGCCAGCGGCAgcatcagtagcagcagcagtagcagcaacagtagcagcagcagcagcagcagtggacaTGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGCGGCGAACGTTGCCGCCGAGGATCTCACACAGCCGCCGCCGATGAAGGTAGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTCTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGccacagcgacagcaacggcGACGTCAACGACGAAAAAGACTGAGaacaacgctgctgctgttgctggcagcaacagtagcaattGCGCCGAATCGCATAGCATATCAGTGAATACGCCCGCCGAGCTTGTGCAGATCAAGAGCGAGAACGTGGAGGCGTCCACAtccagcagtggcagcataTTGGAAAAGCATCTGACTACCAGCTATGCGGCTCAGCAAGCGGCACGCAAGCACTCCGCCGTCAACGATGACGATGCACGCGTCCTGCTCGAGTTTGCCAACTCGAAGCAGCTTCCGATGCCGGGGAACAGCAATCATACCACGTTTGTGGTGAACGCGGCCAGTTTTGCGTCAGCGGGTTCCGTAtttgccagcggcagcagcagcagcggtgtcAATATGCAAAAGTCAACCAAACCGGGCTGTGGCGATGAGTACATTCTGCCCGATGACACCAAGCTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCGTCCAcctcgcagcagcaacagcagcatctgcaacaacaaacacaacagcagcagcaacaacaatctttGCAGCAGGCGCAACCATCCGCCTTCACTGAGTTTAGTTTTCTGTACcaccaaaacacaacaacaccaacagcagctgtagcagcagcggcagcggcaacaacggcGACATCTACTGCTTCCAACTTTGCACCGTTTGGcattcagcaacagcaacaacagttgcagttgcaacatcATCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCAACGCTTGCATCCTCGTCGAGCAATTCGTCTGCATTGGACCAGGAGTGCTCGATGAATGCCACGTTTCGCGTGGCAAAGCCACAATCAATGCTGGGCGCCTGGTATCAGCCGCATCAGGCGCAGCATCAGGTGGCATCTTCGCACAGTCCACAACATGTGGATCAGCCGAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGATAGCGATATGAGTGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACAgctgagcaacagcagcagccatatGCCATCCGCTTCCACATCGaccacatcatcatcgtttGCTGCCGCAGCAACGGAGAGCAGTCTCGTCGGTGGCCTGGGTCTAAATATTCGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAGCAGGAAAGCAACTGCGACATAGAGAACTCTTGGAGTCAATCGatgTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCACGACTATTACCCGGCGCAGGATCTcagtggccagcagcagcagcagcgagagcAAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCACAGCCGGGCGAGCTGGAAGCTTCCTCGAGCTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCTTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGCGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCTCAGCGAAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACACTGTGTGGCCATCTTCGAGAAGCTAAAGGAGCGCAATGCGCACATGATTGGCGAGCACAACTATGTGCGCCAGAACCGGCGTCTCATCTGCACGCAGGCGCTGGTCAGCGCTGCGATGCTCGCCCAGCCGCTGGCTCAGCAGTCAGAGCAGCAaatggagctggagcagcagcaacagcatcagttGTTGCAGGTGAGCCACACCACAGGCGGTGCTGAGCACGAGGATTCCAAGGATGGTATTGTGAAGATTAAGCAGGAACACTGTCAGGACAAGCACGATCCAGCATCGGAGCAATTGCTTGGCCACTTGGAGCTGCCGGATGTGAAGGATGCTggcctgctcgaagccagcgGTGAAAACGGACGCGATGCGGACATGAAGCCGCCAACCACTGTTGCTGAGCTGGACGAGAAACCGACCATAGCACCGCTGGCCATGACGACACCCGCAGCCAAACTGGCTGCTCTTTATCGCATGCTAATTGCCTACAACGAATCGAAGCTGGGCCAGGAGCGCAACAATTTGAGCGAACTGGAGCAAAAGGCCATGGAGAAATCTATATTCTTGTGCTACATTTGTCGCACCGATTTCCCCTCTGTGAAGCTGTACGATGCGCATCTAACCGAGCATCCCGCCGAGTGTTTCACTTGCGGCAAGAAATTCTATCGCTGGAAGAACTTTTCGCTGCACCTGAAACGCCATCTGGGCTGGAAGGAGTTCGGCTGCTATGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCTCTCGTCGAGCACATGCGGATGCACACTGGCCAGACGCCACTCAAGTGCAAAATATGCGGCAAGAAGTTCAAGCGATACTCGAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTTTGCCACTGTGGCGAAGTGCTGCCCTCAAAGGCGCGCTTCCTTTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCGAACTCGCTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTCGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATTAAGGCGCACATGGCGACGCATTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACACTCGTGGGTGCACGCGAATCGAACGGCCAAACCGTTCAAGTGCGAGTACTGCCCCAAGGCGTTTGTGCGCGAGTTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGCAACAAGAAGTTCACGTGCGATCAATGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAACATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNNGGLDSALAAAVISSSSRCSVASTESVASTPPAVDIKPDVASVPTATATQPPHPPQPPQPSPPPAATTTTAAAAASTTTSTSQSTAPKAVALLDNASSSSNNSSSNNNNNHNKLSNPPIKAVKSAPPTTEAPATTSNNNTPTISNVSAVYPANLATDYRYEQQQQPQVQQQHQQLHGFPRGITTTLVIPQAPPQQHNNFLANQQPPAHFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTATQPHQKPPPAYGAAISQIRSQHNQNKQQHQHHQQQQQQQQPQSITVHQHNANAAPPSGKQQHNSKIHADIFLNPPPPPQLTIPSSASASSLSLSLSLSSSTSSRLQHPQQHHQQSHAASSSSSSSSNYAATSCAPSSSVALMSGTSSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEGEDEDDQQGWPNSDEEDHVKVPHEHVEDGDDEHEDSRSRVAPKTTTKKSRKTKSSGRLHKRASKHQMTTTTEDEDDFMSIGSSCAESDHHPEEQLQQQQPQQQHPQQLARNPQQLASAGGAAQLAASSSPAQLCTAPSTSSGAAVAAAAAVASGGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPMDEYDAVEVEMQLEQKPSLEHASGSISSSSSSSNSSSSSSSSGHGTTSVIRMASTSAANVAAEDLTQPPPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATATSTTKKTENNAAAVAGSNSSNCAESHSISVNTPAELVQIKSENVEASTSSSGSILEKHLTTSYAAQQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGSSSSGVNMQKSTKPGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQHLQQQTQQQQQQQSLQQAQPSAFTEFSFLYHQNTTTPTAAVAAAAAATTATSTASNFAPFGIQQQQQQLQLQHHPQHGSSEATNAATLASSSSNSSALDQECSMNATFRVAKPQSMLGAWYQPHQAQHQVASSHSPQHVDQPSNFIAALSAVDCCSAAVDSDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQREQKRFDFNAVASEYAQPGELEASSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVSAAMLAQPLAQQSEQQMELEQQQQHQLLQVSHTTGGAEHEDSKDGIVKIKQEHCQDKHDPASEQLLGHLELPDVKDAGLLEASGENGRDADMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
-