Dsor001643.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila sordidapex
Gene Symbol
-
Assembly
GCA_035043295.1
Location
JAWNNA010000239.1:1142843-1149297[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.056 3.6 8.3 0.2 1 23 1374 1397 1374 1397 0.94
2 13 5.1 3.2e+02 2.1 0.2 1 23 1567 1589 1567 1589 0.91
3 13 0.0002 0.013 16.0 2.7 2 23 1592 1613 1592 1613 0.97
4 13 7.9e-05 0.005 17.3 0.2 3 23 1621 1641 1619 1641 0.98
5 13 6.5e-07 4.1e-05 23.8 4.1 2 23 1648 1669 1647 1669 0.97
6 13 6.2 3.9e+02 1.9 0.4 5 23 1682 1700 1680 1700 0.96
7 13 1.5 97 3.8 5.4 3 23 1707 1728 1705 1728 0.93
8 13 0.16 10 6.8 0.2 2 23 1739 1759 1738 1759 0.96
9 13 6.3e-05 0.004 17.6 0.4 1 19 1765 1783 1765 1787 0.95
10 13 1.8e-05 0.0011 19.3 0.5 1 23 1795 1817 1795 1817 0.98
11 13 0.00012 0.0074 16.7 7.6 1 23 1823 1845 1823 1846 0.96
12 13 0.00023 0.014 15.8 5.9 1 23 1851 1873 1851 1873 0.98
13 13 0.032 2 9.1 8.2 1 23 1879 1901 1879 1902 0.95

Sequence Information

Coding Sequence
ATGGTGGACAGTGTGCAGTGCCCCGTATGCACCTTGTATCTGCATGCGGGAATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGAAAATGACCattgctggcaacaacaatggtggTCTGGACAGCGCCCTGGCGGCAGCTGTCATCtccagcagcagtcgcagcagcgtTGCCTCAACCGAAAGCGTTGCCTCAACGCCGCCCGCTTGTGATGTCAAGCCAGATGTGGCGTCAGTaccaacagcgacagcaacacaACCACCACAGCCGACACAACTACCCcaaccaccacaaccaccacaaccaccccaaccaccaccagcaacaacaacagcagcagcatcaacaacaagcacatcGCAATCAACGGCATCCAAACCTGTCGCATTGCTGgacaacgccagcagcagcagtagcaacatcaacagtagcaacagcaccagcggcagcaacaataataacaaattgagCAATCCACCGATTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCTACCacatccaacaacaacacacccACCATAAGCAGCGTGGCTGCTGTCTATCCGGCAACCCTGGCAACCGACTATCGCtacgaacagcagcaacagccacaccaacagcagcagctgcatggcTTTCCACGTGGCACCACCACTACACTGGTGATACCACAAgcgcagccgcaacagcaccACAATTTTCTGGCAAACCAACAGCCGCCTGCGCAGTTTgcccaccagcaacagcagccgcagtcgaCCATGAAGTTCACgtatgcaacagcagcgttgCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAGCCGACGGCAACGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCACCGCCATCAGTCAAATTCGATCTCAGCATAaccaaaacaagcaacaacaccaacaccaccaacaacaacagcaacaacaacacataaacGTACAGCAgcacaatgcaaatgcagcaccACCGagtggcaagcaacaacacaacagcaaaatccATGCGGATATCTTTCTGAATCCACCCCCACCGCCACAGCTCACAATTCCGTCGTCGGCGTCGGTGTCAtcgttgtcattgtcgctGTCCCTGTCGTCATCGACCTCCTCAAGACTGCAACATCCccaacagcaccaccaacaatcCCATGCtgctagcagcagcaactatgcAGCCACCAGCTGCGCTCCCAGCTCCTCGGTTGCACTGATGTCCGGGTCACCGTCGGCACGTACCAGCAGTCGCCAGTCAAGCAATTCGCCCTTTGGTGCCCTACTGAATGCGGCTGCGCACGCTGCCTGCTCCTCGCCCGCTTCGACTGGGGCGTCTGTGCTGCGCTTTGCCGAGTCGCCAGTGGCCCACTATCTGGAGCGGGAGAACGGTGATTTCATAGTGCAGGAGACGCCCAAGCATATCGTGGAGTGTGTCGAGAAGGACGACGGTGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTTCACATACACGACGATGacgaagaagaggaagaggaggaggaggacgacgaTGATCAGCAGGGtTGGGCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGTCGAGTTGCATCCAAAACGACAACGAAAAAGTCACGCAAGACAAAAACGAGTGGCAGATTGCACAAGCGCGCCTCCAAGCATCAGCTGGCCACGACGACGGAGGACGAGGACGACTTCATGAGTATAGGCAGCAGTTGTGCCGAAAGCGAGCATCATccagaggagcagcagccgcagcagcagcatccgcaGCATGTATCGTCGGCTGGGGCAGCACAATTGGCGACGAGCTCGTCGCCAGCTCAACTTTGCACTGCGCCCTCCACGAGcagtggtgctgctgttgccgttgctgttgctgctgccgccgccagtAGTGGCAAATTCATGGCCAGCGGCACTATCAAGTCAAAAAAGAATCGGGTAACGGTGCTTAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGAGTCGCATTGGCGCAGCGCGTCCGTTTGCCGCTGTGGCGCCCATACCGCTCGTCAAGGTTGAAAAGGAGGAACCCATGGATGAATATGATGCCGTTGAAGTCGAGATGCAGTTGGAGCAGAAGCCTAGCCTGGAGCatgccagcggcagcagtagtagcagcagcagtagcagcaacagtagcagcagcagcagcagtggacATGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGGCGCGAACGTTGCCGCCGAGGACCTCACACAGCCGCCGCCCATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTCTCGGCACCTGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCacagcgacggcgacgtcaacgacgaaaaagACTGAGaacaacgctgctgctgttgctactggcagcaacagtagcagttGCGCCGCATCCCATAGCATATCAGTGACTACGCCCGCCGAGCTAGTGCAGATCAAGAGCGAGAACGTGGAGGCGTCCACAtccagcagtggcagcatATTGGAAAAGCATCTGACTACCAACTATGCGGCACAGCAAGCGGCACGCAAGCACTCCGCCGTCAATGATGACGATGCGCGTGTTCTGCTCGAGTTTGCCAACTCGAAGCAGCTGCCGATACCGGGCAATAGCAATCATACTACATTTGTGGTGAACGCGGCCAGTTTTGCGTCAGCGGGTTCCGTATttgccagcggcagcagcggtgTCAATGTGCAAAAGTCAACCAAGCCTGGTTGTGGCGATGAGTACATTCTTCCCGATGACACCAAACTGGAGGTGGATGAAATTGTGATATCCTCATCGTCTTCCTATGCCTCCACctcgcagcaacagcagcagcatctgcaacaacaaacacagcagcagcaacaacaatctttGCAGCAGGCGCAACCATCCGCCTTCACTGAGTTTAGTTTTCTGTACcaccaaaacacaacaacaacagcagcagcaacaacggcggCGACACCTACTACTTCCAACTTTGCACCGTTTGgcattcagcagcagcaacagcaacaacagttgcagttgcaacatcaTCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCAACGCTTGCGTCCTCGTCGAGCAATTCGTCTGCATTGGACCAGGAGTGCTCGATGAATGCCACGTTTCGCGTGGCAAAGCCACAATCAATGCTGGGCGCCTGGTATCAGCCACATCAGGCGCAGCATCAGGTGACATCTTCGCACAGTCCACAACATGTGGATCAGCCTAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGATAGCGATATAAGTGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACagctgagcaacagcagcagccatatGCCCTCCGCTTCGACATCGACCACATCGTCATCgtttgctgcagcagcaacggagAGCAGTCTCGTCGGTGGCCTGGGTCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAGCAGGAAAGCAACTGCGACATTGAGAACTCTTGGAGTCAGTCGATGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAACCAGCAGCTGGCCGATTGGCGTCACGACTACTATCCGGCGCAAGATCTcagtggccagcagcagcagcagcgagagcaAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCGCAGCCGAGCGAGCTGGAAACTTCCTCGAGCTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACTTCCCGTGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCGCAACGGAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACACTGTGTGGCCATCTTCGAGAAGCTAAAGGAGCGCAATGCGCATATGATTGGCGAGCACAACTATGTTCGCCAGAATCGCCGTCTCATCTGCACGCAGGCGCTGGTCAACGCTGCGATGCTGGCCCAGCCGATGGGTCAGCAGCCAGAGCAGCagatggagctggagcagcagcaacagcatcagttGCTGCAGGTGGTCCACAGCACGGGCGGAGCCTTGCACGAGGATTCCAAGGATGGTATTGTGAAGATTAAGCAGGAGCACTGTCAGGATAAGCACGATCCGGCATCGGATCAATTGCTTGGCCAGTTGGAGATGCCGGATGTGAAGGACGCTGGCCTGCTCGATGCCAGCGGGGAAAGCGGACGCGATGCAGACATGAAGCCACCAACCACTGTTGCTGAGTTGGACGAAAAACCGACCATAGCACCGCTGGCCATGACGACGCCCGCTGCCAAACTGGCTGCTCTTTATCGCATGCTGATTGCCTACAACGAATCAAAGCTGGGCCAGGAGCGCAACAATCTGAGCGAACTGGAGCAGAAGGCCATGGAGAAATCCATTTTCTTGTGTTACATTTGCCGCACCGATTTCCCCTCTGTGAAGCTGTACGATGCGCATCTAACAGAGCATCCCGCCGAGTGTTTCACCTGCGGCAAGAAATTCTATCGCTGGAAGAACTTCTCCCTGCACCTGAAACGCCATCTGGGTTGGAAGGAGTTCGGGTGCTATGTCTGCGACAAGAAATTTGTGGTGCGCAGCGCTCTCGTCGAGCACATGCGGATGCACACTGGCCAGACGCCACTGAAATGCAAGATATGCGGCAAAAAGTTCAAGCGATACTCGAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTGTGCCACTGTGGCGAAGTGCTGCCCTCAAAGGCGCGCTTTCTGTGGCACAAGGAAACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCCAACTCGCTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTCGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCGAAGACATCGATTAAGGCGCACATGGCGACGCACTCGACCGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGCACGGCCAAACCGTTCAAGTGCGAATACTGCCCCAAGGCGTTCGTTCGCGAATTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGCTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGCAACAAGAAGTTCACGTGCGATCAGTGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAGCATCTGAAGATACATCATTCGCGCGATCCCTTCACAGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVKMTIAGNNNGGLDSALAAAVISSSSRSSVASTESVASTPPACDVKPDVASVPTATATQPPQPTQLPQPPQPPQPPQPPPATTTAAASTTSTSQSTASKPVALLDNASSSSSNINSSNSTSGSNNNNKLSNPPIKAVKSAPPTTEAPATTSNNNTPTISSVAAVYPATLATDYRYEQQQQPHQQQQLHGFPRGTTTTLVIPQAQPQQHHNFLANQQPPAQFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTATQPHQKPPPAYGTAISQIRSQHNQNKQQHQHHQQQQQQQHINVQQHNANAAPPSGKQQHNSKIHADIFLNPPPPPQLTIPSSASVSSLSLSLSLSSSTSSRLQHPQQHHQQSHAASSSNYAATSCAPSSSVALMSGSPSARTSSRQSSNSPFGALLNAAAHAACSSPASTGASVLRFAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEEEEDDDDQQGWANSDEEDHVKVPHEHVEDGDDEHEDSRSRVASKTTTKKSRKTKTSGRLHKRASKHQLATTTEDEDDFMSIGSSCAESEHHPEEQQPQQQHPQHVSSAGAAQLATSSSPAQLCTAPSTSSGAAVAVAVAAAAASSGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPMDEYDAVEVEMQLEQKPSLEHASGSSSSSSSSSNSSSSSSSGHGTTSVIRMASTSGANVAAEDLTQPPPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATSTTKKTENNAAAVATGSNSSSCAASHSISVTTPAELVQIKSENVEASTSSSGSILEKHLTTNYAAQQAARKHSAVNDDDARVLLEFANSKQLPIPGNSNHTTFVVNAASFASAGSVFASGSSGVNVQKSTKPGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQHLQQQTQQQQQQSLQQAQPSAFTEFSFLYHQNTTTTAAATTAATPTTSNFAPFGIQQQQQQQQLQLQHHPQHGSSEATNAATLASSSSNSSALDQECSMNATFRVAKPQSMLGAWYQPHQAQHQVTSSHSPQHVDQPSNFIAALSAVDCCSAAVDSDISEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQREQKRFDFNAVASEYAQPSELETSSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVNAAMLAQPMGQQPEQQMELEQQQQHQLLQVVHSTGGALHEDSKDGIVKIKQEHCQDKHDPASDQLLGQLEMPDVKDAGLLDASGESGRDADMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
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