Dvil004829.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila villosipedis
Gene Symbol
-
Assembly
GCA_035043025.1
Location
JAWNNF010000022.1:9019251-9025845[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.05 3.2 8.3 0.2 1 23 1403 1426 1403 1426 0.94
2 13 4.5 2.9e+02 2.1 0.2 1 23 1596 1618 1596 1618 0.91
3 13 0.00018 0.012 16.0 2.7 2 23 1621 1642 1621 1642 0.97
4 13 7e-05 0.0045 17.3 0.2 3 23 1650 1670 1648 1670 0.98
5 13 5.8e-07 3.7e-05 23.8 4.1 2 23 1677 1698 1676 1698 0.97
6 13 5.5 3.5e+02 1.9 0.4 5 23 1711 1729 1709 1729 0.96
7 13 1.4 87 3.8 5.4 3 23 1736 1757 1734 1757 0.93
8 13 0.15 9.3 6.8 0.2 2 23 1768 1788 1767 1788 0.96
9 13 5.6e-05 0.0035 17.6 0.4 1 19 1794 1812 1794 1816 0.95
10 13 1.6e-05 0.001 19.3 0.5 1 23 1824 1846 1824 1846 0.98
11 13 0.0001 0.0067 16.7 7.6 1 23 1852 1874 1852 1875 0.96
12 13 0.0002 0.013 15.8 5.9 1 23 1880 1902 1880 1902 0.98
13 13 0.029 1.8 9.0 8.2 1 23 1908 1930 1908 1931 0.95

Sequence Information

Coding Sequence
atggtGGACAGTGTGCAGTGCCCCGTGTGCACCTTGTATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCattgctggcaacaacaatggtggTCTGGACAGCGCCCTGGCGGCAGCTGTCATCTCCAGCAGCAGTCGCTGCAGCGTTGCCTCAACCGAAAGCGTCGCCTCAACGCCGCCTGCTGTTGGTGTCAAACCGGATGTGGCATCAGTaccaacagcgacaacaacacaaccgccacaaccaccacaaccaccccaaccaccaccaccagcagcagcaacaacaacaacagcaggagcagtagcatcaacaacaagcacattGCAATCAACAGCACCCAAGGCTGTTGCATTGCTggacaacaccagcagcagcagtagcaacaacagcagcagcagtagcaacaacagcagcagcagcagcaacaacaacaacaacaacaaattgagcaATCCACCGACTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCATAAGCAACGTGTCTGCTGTCTATCCGGCAACCCTGGCAACCGACTATCGCtacgaacagcagcaacagcaacagccacagctacagcagcagcaccagcagctgcaTGGCTTTCCACGTGGCACCACCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAACCAACAGCCATCTGCGCACTTTgcccaccagcaacagcagccgcagtcgaCCATGAAGTTCACgtatgcaacagcagcgttgCCTCCGCCTCCCTTGCAGCTTTTCGCACAGCAGCCGACGGCAGCGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGcataaccaaaacaaacaacaacaccaacaccaccaacaacagcaacagcaaccacaacacaTAAGCGTACAACAGcataatgcaaatgcagcacCACCGagtggcaaacaacaacacaatggCAAAATCCATGCGGATATATTTCTGAatccaccgccaccgccacagCTCACAATTCCATCGTCGGCGTCGGCatcatcgttgtcgttgtcgctgtccCTGTCGTCATCGACCTCCTCAAGACTGCAACATCCCcaacagcaccaccaacaatCCCATGCggctagcagcagcagcagtagcagtagcaacagcaactatgcAGCAACCAGCTGCGCTCCCAGCTCCTCGGTTGCTCTGATGTCCGGCACATCGTCGGCACGCGCCAGCAGTCGCCAGTCGAGCAATTCACCTTTTGGTGCCCTGCTGAATGCGGCTGCGCACGCTGCCTGCTCCTCGCCCGCTTCGACTGGGGCGTCTGTGCTGCGCTATGCCGAGTCGCCAGTGGCCCACTATCTGGAGCGGGATAACGGTGATTTCATTGTGCAGGAGACGCCCAAGCACATTGTGGAGTGTGTCGAGAAAGACGACGGTGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTCCACAtacacgacgacgacgaagaggaggaggaggacgaggatGATCAGCAGGGttgGGCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGTCGAGTTGCACCCAAAACGACAACGAAAAAGTCACGCAAGACAAAATCGAGTGGCAGATTGCACAAGGGCGCCTCCAAGCATCAGCTGGCCACGACGACGGAGGACGAGGACGACTTCATGAGCATAGGCAGCAGTTGTGCCGAAAGCGATCATCATCCagaggagcagctgcagcaacagcagccgcagcaacagcatccgcAGCAATTAGCATCGGCTGGGGGGGCAGCACAGTTGGTGGCGAGCTCATCGCCGGCTCAACTTTGCACTGCGCCCTCCACGAGCAgtggagctgttgttgttgctgctgctgccgccgccactGGTGGTAAAGTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGACTCGCATTGGTGCAGCGCGTCCCTTTGCCGCTGTAGCGCCCATACCGCTCGTCAAAGTGGAAAAGGAGGAACCCATGGATGAATATGATGCTGTTGTGGTCGAGATGCAGTTGGAGCAAAAGCCCAGCCTAGAGCATGctagcggcagcagcagtagcagcagcagtagcagcaacagtagcagcagcagcagcagcagcagtggacATGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGCGGCGAACGTGGCCGCCGAGGATCTCACACAGCCGCCGTCTATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTCTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGccacagcgacagcaacgGCGACGCCAACGACGAAAAAGACTGAGAacaacgctgctgctgttgcttctggcagcaacagtagcaattGCGCCGAATCCCATAGCATATCAGTGAATACGCCCGCCGAGCTTGTGCAGATCAAGAGCGAGAACGTGGAGGCGTCCACATCGAGCAGTGGCAGCATATTGGAAAAGCATCTGACTACCAGCTATGCGGCACAGCAGGCGGCACGGAAGCACTCCACCGTCAACGATGACGATGCACGTGTGCTGCTCGAGTTTGCCAACTCGAAGCAGCTGCCGATGCCGGGCAACAGCAATCATACCACGTTTGTGGTGAACGCGGCCAGTTTTGCGTCAGCGGGTTCCGTAtttgccagcggcagcagcagcagtggtgTCAATGTGCAAAAGCCAACCAAGCCGGGCTGTGGCGATGAGTACATTCTGCCCGATGACACCAAGCTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCAcctcgcagcagcaacagcagcatctccaacaacaaacacaacagcagcagcagcagcaacaacaatctttGCAGCAGGCGCAACCATCCGCCTTCACTGAGTTTAGTTTTCTGTACcaccaaaacacaacaacaacaacagcagctgcagcagcagcgggagcGGCCACAACGGCGACATCTACTACTTCCAACTTTGCACCGTTTGGcattcagcaacagcaacaacagttgcagttgcaacatcATCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCAACGCTTGCATCCTCGTCGAGCAATTCGTCTGCATTGGACCAGGAGTGCTCGATGAATGCCACGTTTCGTGTGGCAAAGCCACAATCAATGCTGGGCACCTGGTATCAGCCACATCAGGCGCAGCATCAGGTGACATCTTCGCATAGTCCACAACATGTGGATCAGCCGAGCAATTTTATTGCAGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGAGAGCGATATGAGCGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACAgctgagcaacagcagcagccatatGCCATCCGCTTCGACATCAACCACATCGTCATCGTTTGCTGCCGCAGCAACAGAGAGCAGTCTCGTCGGTGGCCTGGGTCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAACAGGAAAGCAACTGCGACATAGAGAACTCTTGGAGTCAATCGaTGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCACGACTATTATCCGGCGCAGGATCTCagtagccagcagcagcagcagcagcgagagcAAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCACAGCCGGGCGAGCTGGAAGCTTCCTCGAGCTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGCGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCTCAACGGAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACATTGTGTGGCCATATTCGAGAAGCTAAAGGAGCGCAATGCGCACATGATTGGCGAGCACAACTATGTGCGCCAGAATCGGCGTCTCATCTGCACGCAGGCGCTGGTCAGCGCTGCGATGCTCGCCCAGCCGCTGGCTCAGCAGTCAGAGCAGCAAATGGAgctggaacagcagcaacagcatcagttGCTGCAGGTGAGCCACAGCACCGGCGGCGCCGAGCACGAGGATTCCAAGGATGGTATTGTGAAGATTAAGCAGGAACATTGTCACGACAAGCACGATCCAGCATCGGAGCAATTGCTTGGCCACTTGGAGCTGCCGGATGTGAAGGATGCTGGCCTGCTCGAAACCAGTGGTGAAAACGGACGCGATGCGGACATGAAGCCACCAACTACTGTTGCTGAGCTTGACGAGAAACCGACCATAGCACCGCTGGCCATGACGACGCCCGCTGCCAAACTGGCTGCTCTTTATCGCATGCTAATTGCCTACAACGAATCGAAGCTGGGCCAGGAGCGCAACAATCTAAGCGAACTGGAGCAAAAGGCAATGGAGAAATCTATATTCTTGTGCTACATTTGCCGCACCGATTTCCCCTCTGTGAAGCTGTACGATGCGCATCTAACCGAGCATCCCGCCGAGTGTTTCACTTGCGGCAAGAAATTCTATCGCTGGAAGAACTTCTCGCTGCACCTGAAACGCCATCTGGGCTGGAAGGAGTTTGGCTGCTATGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCCCTCGTCGAGCACATGCGGATGCACACTGGCCAGACGCCACTCAAGTGCAAGATATGCGGCAAGAAGTTCAAGCGATACTCGAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTGTGCCACTGTGGCGAAGTGCTGCCCTCAAAGGCTCGCTTCCTGTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCGAACTCGCTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTTGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATTAAGGCGCACATGGCGACGCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGAACGGCCAAACCGTTCAAGTGCGAGTACTGCCCGAAGGCGTTTGTGCGCGAGTTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTTATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGCAACAAGAAGTTCACGTGCGATCAATGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAACATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNNGGLDSALAAAVISSSSRCSVASTESVASTPPAVGVKPDVASVPTATTTQPPQPPQPPQPPPPAAATTTTAGAVASTTSTLQSTAPKAVALLDNTSSSSSNNSSSSSNNSSSSSNNNNNNKLSNPPTKAVKSAPPTTEAPATTSNNNTPTISNVSAVYPATLATDYRYEQQQQQQPQLQQQHQQLHGFPRGTTTTLVIPQAPPQQHHNFLANQQPSAHFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTAAQPHQKPPPAYGAAISQIRSQHNQNKQQHQHHQQQQQQPQHISVQQHNANAAPPSGKQQHNGKIHADIFLNPPPPPQLTIPSSASASSLSLSLSLSSSTSSRLQHPQQHHQQSHAASSSSSSSSNSNYAATSCAPSSSVALMSGTSSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEDEDDQQGWANSDEEDHVKVPHEHVEDGDDEHEDSRSRVAPKTTTKKSRKTKSSGRLHKGASKHQLATTTEDEDDFMSIGSSCAESDHHPEEQLQQQQPQQQHPQQLASAGGAAQLVASSSPAQLCTAPSTSSGAVVVAAAAAATGGKVMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASTRIGAARPFAAVAPIPLVKVEKEEPMDEYDAVVVEMQLEQKPSLEHASGSSSSSSSSSNSSSSSSSSSGHGTTSVIRMASTSAANVAAEDLTQPPSMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATATPTTKKTENNAAAVASGSNSSNCAESHSISVNTPAELVQIKSENVEASTSSSGSILEKHLTTSYAAQQAARKHSTVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGSSSSGVNVQKPTKPGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQHLQQQTQQQQQQQQQSLQQAQPSAFTEFSFLYHQNTTTTTAAAAAAGAATTATSTTSNFAPFGIQQQQQQLQLQHHPQHGSSEATNAATLASSSSNSSALDQECSMNATFRVAKPQSMLGTWYQPHQAQHQVTSSHSPQHVDQPSNFIAALSAVDCCSAAVESDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSSQQQQQQREQKRFDFNAVASEYAQPGELEASSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVSAAMLAQPLAQQSEQQMELEQQQQHQLLQVSHSTGGAEHEDSKDGIVKIKQEHCHDKHDPASEQLLGHLELPDVKDAGLLETSGENGRDADMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
-