Dkok010787.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kokeensis
Gene Symbol
-
Assembly
GCA_035042145.1
Location
JAWNLT010000346.1:12552359-12558711[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.052 3.3 8.3 0.2 1 23 1357 1380 1357 1380 0.94
2 13 8.4 5.4e+02 1.4 0.2 1 23 1550 1572 1550 1572 0.91
3 13 0.00019 0.012 16.0 2.7 2 23 1575 1596 1575 1596 0.97
4 13 7.2e-05 0.0046 17.3 0.2 3 23 1604 1624 1602 1624 0.98
5 13 6e-07 3.9e-05 23.8 4.1 2 23 1631 1652 1630 1652 0.97
6 13 5.7 3.7e+02 1.9 0.4 5 23 1665 1683 1663 1683 0.96
7 13 1.4 91 3.8 5.4 3 23 1690 1711 1688 1711 0.93
8 13 0.15 9.7 6.9 0.2 2 23 1722 1742 1721 1742 0.96
9 13 5.8e-05 0.0037 17.6 0.4 1 19 1748 1766 1748 1770 0.95
10 13 1.6e-05 0.0011 19.3 0.5 1 23 1778 1800 1778 1800 0.98
11 13 0.00011 0.0069 16.7 7.6 1 23 1806 1828 1806 1829 0.96
12 13 0.00021 0.013 15.8 5.9 1 23 1834 1856 1834 1856 0.98
13 13 0.03 1.9 9.1 8.2 1 23 1862 1884 1862 1885 0.95

Sequence Information

Coding Sequence
ATGGTGGGCAGTGTGCAGTGCCCCGTATGCACCTTGTATCTGCATGCGGGGATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGAAAATGACCattgctggcaacaacaattgtggtCTGGACAGCGCCCTGGCGGCAGCTGTCATCTCCAGTAGCAGTCCAAGCAGCGTTGCCTCGACCGAAAGCGTTGTCTTAACGTCGCCTGTTGGTGATGTCAAGCCAGATGTAGCGTCAGTACCAATAGCGACAGCAACGCAACCACCACAGTCGCCACAACTTCCCcaaccaccacaaccaccaccaccaccagcaacaagaacagcagcagcatcaacaacaagcacatcGCAATCAATAGCATCCAAAGCTGTCGCATTGCTGGacaccgccagcagcagcagtagcaacagcaccagcggcagcaacaataataacaaattgagCAATCCACCGATTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCACAAGCAGCGTGGCTGCTGGCTATCCGGCAACCCTGGCAACCGACTATCGCtacgaacagcagcaacagccacaacaacagcagcagctgcatggcTTTCCACGTGGCACCACCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAACCAACAGCCGACTGCGCAGTTTGcccatcagcaacagcagccgcagtcgaCCATGAAGTTCACgtatgcaacagcagcgttGCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAGCCGACGGCAACGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCACCGCCATCAGTCAAATTCGATCTCAGCATAAccaaaacaagcaacaacaccaacaccaccaacaacaacagcaacaacaacacataaacGTTCAGCAgcacaatgcaaatgcagcaccACCGagtggcaagcaacaacacaacagcaaaatccATGCGGATATCTTTCTGAatccaccgccaccgccacagCTCACAATTCCATCGTCGGCGTCGGTGTcatcgttgtcgctgtcgtcaTCGACCTCCTCAAGACTGCAACATCCccaacagcaccaccaacaatcCCATGCtgctaacagcagcaactatgcAGCCACCAGCTGCGCTTCCAGCTCCTCGGTTGCACTGATGTCCGGATCATCGTCGGCACGCGCCAGCAGTCGCCAGTCAAGCAATTCGCCCTTTGGTGCCCTACTGAATGCGGCTGCGCATGCTGCCTGCTCCTCGCCCGCTTCGACTGGGGCGTCTGTGCTGCGCTATGCCGAGTCGCCAGTTGCCCATTATCTGGAGCGGGAGAACGGTGATTTCATAGTTCAGGAGACGCCCAAGCATATCGTGGAGTGTGTCGAGAAGGACGACGGTGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTTCACATACACGACGATGacgaagaagaggaagaggaggaggacaACGATGATCAGCAGGGttgGCCAAACAGCGATGAGGAAGATCATGTCAAGGTGGCACACGAGCCTGTcgaggatgacgatgatgagctCGAGGATAGTCGCAGTCGAGTTGCATCCAAAACGACAACGAAAAAGTTACGCAAGACAAGAACGAGTGCCAGATTGCAGAAGCGCGCCTCCAAGCAGCATCAGCTGGCCACGACGACGGAGGACGAGGACGACTTCATGAGCATAGGCAGCAGTTGTGCCGAAAGCGAGCATCATccagaggagcagcagccgcagcagcagcatccgcaGCATGTATCGTCGGCTGGGGGGACAGCAGAATTGGCGGCGAGCTCGTCGCCAGCTCAACTTTGCACTGCGCCCTCCACAAGcagtggtgctgctgttgctgttgccgccgccagTAGTGGCAAATTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTTAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGAGTCGCATTGGCGCAGCGCGTCCGTTTGCCGCTGTGGCGCCCGTACCGCTCGTCAAGGTTGAAAAGGAGGAACCCATGGATGAATATGATGCCGTTGAAGTCGAGATGCAGAAGCCTAGCCTAGAGCatgccagcggcagcagtagtagcagcagcagtagcagtaacagtagcagcagcagcagcagtggacaCGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGGCGCGAACGTTGCCGCCGAGGATCTCACACAGCCGCCGCCCATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTCTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCcacagcgacggcgacgtcaACGACGAAAAAGACTGAGaacaacgctgctgctgttgctactggcagcaacagtagcagttGCGCCGCATCCCACAGCATATCAGTGACTACGCCCGCCGAGCTAGTGCAGATCAAGAGCGAGAACGTGGAGGCGTCCACTtccagcagtggcagcatatTGGAAAAGCATCTGACTACCAGCTATGCGGCACAGCAAGCGGCACGCAAGCACTCCGCCGTCAACGATGACGATGCACGTGTCCTGCTCGAGTTTGCCAACTCGAAGCAGCTGCCGATGCCGGGCAATAGCAATCATACCACGTTTGTGGTGAACGCGGCCAGTTTTGCGTCAGCGGGTTCCGTGTttgccagcggcagcagcggtgCCAATGTGCAAAAGTCAACCAAGCCGGGTTGTGGCGATGAGTTCATTTTACCCGATGAAACCAAACTGGAGGTGGATGAAATTGTGATATCCTCATCGTCTTCCTATGCCTCCACctcgcagcaacagcagcagcatctgcaacaacaaacacaacagcagcagcaacaacaatcttTGCAGCAGGCGCAACCATCCGCCTTCACTGAGTTTAGTTTTCTGTACcaccaaaacacaacaacaacagcagcatcagcaacaacggcGGCGACACCTACTACTTCCAACTTTGCACCGTTTGgcattcagcagcagcaacagcaacaacagttgcagttgcaacatcATCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCAACGCTTGCGTCCTCGTCGAGCAATTCGTCTGCATTGGACCATGAGTGCTCGATGAATGCCTCGTTTCGCGTGGCAAAGCCACAATCAATGCTGGGCGCCTGGTATCAACCACATCAGTCTCAGCATCAGGTGGCATCTTCGCACAGTCCACAACATGTGGACCAGCCTAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGATAGCGACATAAGTGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACagctgagcaacagcagcagccatatGCCCTCCGCTTCGACATCGACCACATCGTCATCgtttgctgcagcagcaacggagAGCAGTCTCGTCGGTGGTCTGGGTCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAGCAGGAAAGCAACTGCGACATTGAGAACTCTTGGAGTCAATCGATGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGTTACAACCAGCAGCTGGCCGATTGGCGTCACGACTACTATCCGGCGCAAGATCTcagtggccagcagcagcagcagcgagagcaAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCACATCCGAGCGAGTTGGAAACTTCCTCGAGCTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACTTCCCGTGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCGCAACGGAAGCCAGCACGTCGCAAAATCTACAAGTGTCCACACTGTGTGGCCATCTTCGAGAAACTAAAGGAGCGCAATGCGCATATGATTGGCGAGCACAACTATGTTCGCCAGAATCGCCGTCTCATCTGCACGCAGGCGCTGGTCAACGCTGCCATGCTGGCCGAGCCGATGGGTCAGCAGCCAGAGCAGCagatggagctggagcagcagcaacagcatcaattGCTGCAGGTGGGCCACAGCACGGACGGCGCGGAGCCCGAGGATTCCAAGGATGGTATTGTGAAGATTAAGCAAGAGCACTGTCAGGATAAGCACGATCCGGCACCGGAACAATTGCTTGGCCACTTGGAGATGCCGGATGTGAAGGACGCCGGCCTGCTCGTTGCCAGCGAGGAAAGCGGACGCGATGCAGACATTAAGCCACCAACCACTGTTCCTGAGTTGGACGAAAAACCGACCTTAGCACCGCTGGCCATGACGACGCCCGCTGCCAAACTGGCTGCTCTTTATCGCATGCTGATTGCCTACAACGAATCAAAGCTGGGCCAGGAGCGCAACAATCTGAGCGAACTGGAGCAGAAGGCCATGGAGAAATCCATTTTCTTGTGCTACGTTTGCCGCACCGATTTCCCCTCTGTGAAGCTGTACGATGCGCATCTAACAGAGCATCCCGCCGAGTGTTTCACCTGTGGCAAGAAATTCTATCGCTGGAAGAACTTCTCCCTGCACCTGAAACGCCATCTGGGTTGGAAGGAGTTCGGCTGCTATGTCTGCGACAAGAAATTTGTGGTGCGCAGCGCTCTCGTCGAGCACATGCGGATGCACACTGGCCAGACGCCACTGAAGTGCAAGATATGCGGCAAAAAGTTCAAGAGATACTCGAACTTAACGCAGCATCGCAAGCGCCACACTAAGATGATGGTGCGCAAAAAGGAATATGTGTGCCACTGTGGCGAAGTGCTGCCCTCAAAGGCGCGCTTTCTGTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCCAACTCACTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTCGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCGAAGACATCGATTAAGGCGCACATGGCAACGCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGCACGGCCAAACCGTTCAAGTGCGAATACTGCCCCAAGGCGTTCGTGCGCGAATTGGATTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGCAACAAGAAGTTCACGTGCGATCAGTGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGCGGCAAGAGCTCCACCACAAAGACCAATCACAACAAGCATCTGAAGATACATCATTCGCGCGATCCCTTCACAGTGGAGGTCTAA
Protein Sequence
MVGSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVKMTIAGNNNCGLDSALAAAVISSSSPSSVASTESVVLTSPVGDVKPDVASVPIATATQPPQSPQLPQPPQPPPPPATRTAAASTTSTSQSIASKAVALLDTASSSSSNSTSGSNNNNKLSNPPIKAVKSAPPTTEAPATTSNNNTPTTSSVAAGYPATLATDYRYEQQQQPQQQQQLHGFPRGTTTTLVIPQAPPQQHHNFLANQQPTAQFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTATQPHQKPPPAYGTAISQIRSQHNQNKQQHQHHQQQQQQQHINVQQHNANAAPPSGKQQHNSKIHADIFLNPPPPPQLTIPSSASVSSLSLSSSTSSRLQHPQQHHQQSHAANSSNYAATSCASSSSVALMSGSSSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEEEDNDDQQGWPNSDEEDHVKVAHEPVEDDDDELEDSRSRVASKTTTKKLRKTRTSARLQKRASKQHQLATTTEDEDDFMSIGSSCAESEHHPEEQQPQQQHPQHVSSAGGTAELAASSSPAQLCTAPSTSSGAAVAVAAASSGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPVPLVKVEKEEPMDEYDAVEVEMQKPSLEHASGSSSSSSSSSNSSSSSSSGHGTTSVIRMASTSGANVAAEDLTQPPPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATSTTKKTENNAAAVATGSNSSSCAASHSISVTTPAELVQIKSENVEASTSSSGSILEKHLTTSYAAQQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGSSGANVQKSTKPGCGDEFILPDETKLEVDEIVISSSSSYASTSQQQQQHLQQQTQQQQQQQSLQQAQPSAFTEFSFLYHQNTTTTAASATTAATPTTSNFAPFGIQQQQQQQQLQLQHHPQHGSSEATNAATLASSSSNSSALDHECSMNASFRVAKPQSMLGAWYQPHQSQHQVASSHSPQHVDQPSNFIAALSAVDCCSAAVDSDISEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQREQKRFDFNAVASEYAHPSELETSSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVNAAMLAEPMGQQPEQQMELEQQQQHQLLQVGHSTDGAEPEDSKDGIVKIKQEHCQDKHDPAPEQLLGHLEMPDVKDAGLLVASEESGRDADIKPPTTVPELDEKPTLAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
-