Dsil011632.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila silvestris
Gene Symbol
-
Assembly
GCA_035043445.1
Location
JAWNMZ010000151.1:16955330-16961872[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.05 3.3 8.3 0.2 1 23 1373 1396 1373 1396 0.94
2 13 4.6 3e+02 2.1 0.2 1 23 1565 1587 1565 1587 0.91
3 13 0.00018 0.012 16.0 2.7 2 23 1590 1611 1590 1611 0.97
4 13 7e-05 0.0046 17.3 0.2 3 23 1619 1639 1617 1639 0.98
5 13 5.8e-07 3.9e-05 23.8 4.1 2 23 1646 1667 1645 1667 0.97
6 13 5.5 3.7e+02 1.9 0.4 5 23 1680 1698 1678 1698 0.96
7 13 1.4 91 3.8 5.4 3 23 1705 1726 1703 1726 0.93
8 13 0.15 9.7 6.8 0.2 2 23 1737 1757 1736 1757 0.96
9 13 5.6e-05 0.0037 17.6 0.4 1 19 1763 1781 1763 1785 0.95
10 13 1.6e-05 0.0011 19.3 0.5 1 23 1793 1815 1793 1815 0.98
11 13 0.0001 0.0069 16.7 7.6 1 23 1821 1843 1821 1844 0.96
12 13 0.0002 0.013 15.8 5.9 1 23 1849 1871 1849 1871 0.98
13 13 0.029 1.9 9.1 8.2 1 23 1877 1899 1877 1900 0.95

Sequence Information

Coding Sequence
atggtGGACAGTGTGCAGTGCCCCGTGTGCACCTTGTATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCAttgctggcaacaacaatggtggTCTGGACAGCGCCCTGGCGGCAGCTGTCATCTCCAGCAGCAGTCGCTGCAGCGTTGCCTCAACCGAAAGCGTCGCCTCAACGCCGCCTGCTGTTGATGTCAAACCAGATGTGGCATCAGTaccaacagcgacagcaacacaACCGCCACAGCCACCACAACCACCCcaaccaacaccaccaccagcagcaacaacaacaacagcagcagcatcaacaacaacaagcacatcGCAATCAGCAGCACCCAAAGCTGTCGCATTGCTggacaacaccagcagcagcagtagcaacaacagcagcagcaacaacaacaataacaacaaattgagcAATCCACCGATTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCATAAGCAACGTGTCTGCTGTCTATCCGGCAACCCTGGCAACCGACTATCGCtacgaacagcagcaacagcaacagccacagctacagcagcagcaccagcagcagcaccagcagctgcaTGGCTTTCCACgtggcaccaccaccacactGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAACCAACAGCCGCCTGCGCACTTTGcccatcagcaacagcagccgcagtcgaCCATGAAGTTCACGTATGCAACAGCGGCGTTGCCTCCGCCTCCCTTGCAGCTTTTTACACAGCAGCCGACAGCAACGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCATAaccaaaacaagcaacaacaccaacaccaccaacaacagcaacaacaacaacaaccacaacacgTAAACGTACAGCAGcataatgcaaatgcagcacCACCGagtggcaaacaacaacacaatagCAAAATCCATGCGGATATCTTTCTGAatccaccgccaccgccacagCTCACAATTCCATCGTCGGCGCCGGCGTCatcattgtcgttgtcgctgtccCTGTCGTCATCGACCTCCTCAAGACTGCAACATCCCcaacagcaccaccaacaatcCCATGctgctagcagcagcagcagtagcagtagcagcagcaactatgcAGCAACCAGCTGCGCTCCCAGCTCCTCGGTTGCTCTGATGTCCGGCACATCGTCGGCACGCACCACCAGTCGCCAATCGAGCAATTCGCCCTTTGGTGCCCTGCTGAATGCGGCTGCGCACGCTGCCTGCTCCTCGCCCGCTTCGACTGGGGCGTCTGTGCTGCGCTATGCCGAGTCGCCAGTGGCCCACTATCTGGAGCGGGATAATGGTGATTTCATAGTGCAGGAGACGCCCAAACACATTGTGGAGTGTGTCGAGAAGGACGACGGTGAATTCTCCGTGATTGAACGCATCTATCAATCGCCACCCAGCGTTCTCCACAtacacgacgacgacgaagaggaggaggaggacgaggatgaTCAGCAGGGTTGGGCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGCCGAGTTGCACCCAAAACGACAACGAAAAAGTCACGCAAGACAAAATCGAGTGGCAGATTGCACAAGCGCGCCTCCAAGCAACAGCTGGCCACGACGACGGAGGACGAGGACGACTTCATGAGCATAGGCAGCAGTTGTGCCGAAAGCGAACATCATCCagaggagcagctgcagcaacagcagccgcagcaacagcatccgcAGCAATTAGCATCGGCTGGGGGGCAGCCCActgttgttgctgctgctgctgccgccagtGGTGGTAAATTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGAGCCGCATTGGCGCAGCGCGTTCCTTTGCCGCTGTAGCGCCCATACCGCTCGTCAAGGTGGAAAAGGAGGAACCCATGGATGAATATGATGCCGTTGAGGTCGAGATGCAGTTGGAGCAAAAGCCGAGCCTAGAGCATGctagtggcagcagcagtagcagcagcagtagcagcaacagtagcagcagcagcagcagtggacaTGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGCGGCGAACGTTGCCGCCGAGGATCTCACACAGCCGCTACCGATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTTTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCACagcgacggcaacggcgacgtcAACGACGAAAAAGACTGAGAacaacgctgctgctgttgctactggcagcaacagtagcaattGCGCCGAATCCCATAGCATATCAGTGAATACGCCCGCCGAGCTTGTGCAGATCAAGAGCGAGAATGTGGAGGCGTCCACAtccagcagtggcagcataTTGGAAAAGCATCTGACTACCAGCTATGCGGCACAGCAGGCGGCACGCAAGCACTCCGCCGTCAACGATGACGATGCACGTGTCCTGCTCGAGTTTGCCAACTCGAAGCAGTTGCCGATGCCTGGCAATAGCAATCATACCACGTTTGTGGTGAACGCGGCCAGTTTTGCGTCAGCGGGTTCCGTATttgccagcggcagcagcagcagcggtggaAATGTGCAAAAGTCAACCAAGCCGGGCTGTGGCGATGAGTACATTCTGCCCGATGACACCAAACTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCAcctcgcagcagcaacagcagcatctccaacaacaaacacaacagcagcagcagcaacaacaatctttGCAGCAGGCGCAACCATCCGCTTTCACTGAGTTTAGTTTTCTGTACCAccaaaacacaacagcaacaacagcagcagcagcagcagcagcggcaacaacggcGACATCTACTACTTCCAACTTTGCACCGTTTGGcattcagcaacagcaacaacagttgcagttgcaacatcATCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCAACGCTTGCATCCTCGTCGAGCAATTCGTCTGTATTGGATCAGGAGTGCTCGATGAATGCCACGTTTCGCGTGGCAAAGCCACAATCAATGCTGGGCGCCTGGTATCAGCCACATCAGGCGCAGCATCAGGTGACATCTTCGCACAGTCCACAACATGTGGATCAGCCGAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGATAGCGATATGAGTGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACAgctgagcaacagcagcagccatatGCCCTCCGCTTCGACATCGACCACATCGTCATCGTTTGCTGCCGCAGCAACGGAGAGCAGTCTCGTCGGCGGCCTGGGTCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAGCAGGAAAGCAACTGCGACATAGAGAACTCTTGGAGTCAATCGATGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCACGACTACTATCCGGCGCAGGATCTcagtggccagcagcagcagcagcgagagcAAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCACAGCCGGGCGAGCTGGAAGCTTCCTCGAGCTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGCGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCTCAACGGAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACACTGTGTGGCCATCTTCGAGAAACTAAAGGAGCGCAATGCGCACATGATTGGCGAGCACAACTATGTGCGCCAGAATCGGCGTCTCATCTGCACGCAGGCGTTGGCGATACTGACCCAGCCGCTGGCTCAGCAGCCAGAGCAGCAaatggagctggagctggagcagcagcagcagcatcagttgcTGCAGGTGGGCCACAGCACGGGCGGCGCCGAGCACGAGGATTCCAAGGATGGTATTGTGAAGATTAAGCAGGAACACTGTCAGGACAAGCACGATCCAGCATCGGAGCAATTGCTTGGCCACTTGGAGCTGCCGGATGTGAAGGATGCTGGCCTGCTCGAAGCCAGCGGTGAAAACGGACGCGATGCGGACATGAAGCCACCAACCACTGTTGCTGAGCTGGACGAAAAGCCGACCATAGCACCGCTGGCCATGACGACGCCCGCTGCCAAACTGGCTGCTCTTTATCGCATGCTAATTGCCTACAACGAATCGAAGCTGGGCCAGGAGCGCAACAATCTGAGCGAACTGGAGCAAAAGGCCATGGAGAAATCTATATTCTTGTGCTACATTTGCCGCACCGATTTCCCCTCTGTGAAGCTGTACGATGCGCATCTAACCGAGCATCCCGCCGAGTGTTTCACCTGTGGCAAGAAATTCTATCGCTGGAAGAACTTCTCGCTGCACCTGAAACGCCATCTGGGCTGGAAGGAGTTCGGCTGCTATGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCTCTCGTCGAGCACATGCGGATGCACACTGGCCAGACGCCACTCAAGTGCAAGATATGCGGCAAGAAGTTCAAGCGATACTCGAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTGTGCCACTGTGGCGAAGTGCTGCCCTCAAAGGCGCGCTTCCTGTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCGAACTCGCTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTCGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATTAAGGCACACATGGCGACGCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGAACGGCCAAACCGTTCAAGTGCGAGTACTGCCCCAAGGCGTTCGTGCGCGAGTTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGTAACAAGAAGTTCACGTGCGACCAATGCGACAAGTCTTTCCATCGCCATTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAGCATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNNGGLDSALAAAVISSSSRCSVASTESVASTPPAVDVKPDVASVPTATATQPPQPPQPPQPTPPPAATTTTAAASTTTSTSQSAAPKAVALLDNTSSSSSNNSSSNNNNNNKLSNPPIKAVKSAPPTTEAPATTSNNNTPTISNVSAVYPATLATDYRYEQQQQQQPQLQQQHQQQHQQLHGFPRGTTTTLVIPQAPPQQHHNFLANQQPPAHFAHQQQQPQSTMKFTYATAALPPPPLQLFTQQPTATQPHQKPPPAYGAAISQIRSQHNQNKQQHQHHQQQQQQQQPQHVNVQQHNANAAPPSGKQQHNSKIHADIFLNPPPPPQLTIPSSAPASSLSLSLSLSSSTSSRLQHPQQHHQQSHAASSSSSSSSSSNYAATSCAPSSSVALMSGTSSARTTSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEDEDDQQGWANSDEEDHVKVPHEHVEDGDDEHEDSRSRVAPKTTTKKSRKTKSSGRLHKRASKQQLATTTEDEDDFMSIGSSCAESEHHPEEQLQQQQPQQQHPQQLASAGGQPTVVAAAAAASGGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARSFAAVAPIPLVKVEKEEPMDEYDAVEVEMQLEQKPSLEHASGSSSSSSSSSNSSSSSSSGHGTTSVIRMASTSAANVAAEDLTQPLPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATATSTTKKTENNAAAVATGSNSSNCAESHSISVNTPAELVQIKSENVEASTSSSGSILEKHLTTSYAAQQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGSSSSGGNVQKSTKPGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQHLQQQTQQQQQQQQSLQQAQPSAFTEFSFLYHQNTTATTAAAAAAAATTATSTTSNFAPFGIQQQQQQLQLQHHPQHGSSEATNAATLASSSSNSSVLDQECSMNATFRVAKPQSMLGAWYQPHQAQHQVTSSHSPQHVDQPSNFIAALSAVDCCSAAVDSDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQREQKRFDFNAVASEYAQPGELEASSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALAILTQPLAQQPEQQMELELEQQQQHQLLQVGHSTGGAEHEDSKDGIVKIKQEHCQDKHDPASEQLLGHLELPDVKDAGLLEASGENGRDADMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
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