Basic Information

Insect: Drosophila differens
Gene Symbol: -
Assembly: GCA_037043665.1
Location: JBAMAZ010000010.1:735784-742320[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.052 3.4 8.3 0.2 1 23 1391 1414 1391 1414 0.94

2 13 4.7 3.1e+02 2.1 0.2 1 23 1582 1604 1582 1604 0.91

3 13 0.00019 0.012 16.0 2.7 2 23 1607 1628 1607 1628 0.97

4 13 7.3e-05 0.0047 17.3 0.2 3 23 1636 1656 1634 1656 0.98

5 13 6.1e-07 3.9e-05 23.8 4.1 2 23 1663 1684 1662 1684 0.97

6 13 5.7 3.7e+02 1.9 0.4 5 23 1697 1715 1695 1715 0.96

7 13 1.4 92 3.8 5.4 3 23 1722 1743 1720 1743 0.93

8 13 0.15 9.9 6.8 0.2 2 23 1754 1774 1753 1774 0.96

9 13 5.8e-05 0.0038 17.6 0.4 1 19 1780 1798 1780 1802 0.95

10 13 1.7e-05 0.0011 19.3 0.5 1 23 1810 1832 1810 1832 0.98

11 13 0.00011 0.0071 16.7 7.6 1 23 1838 1860 1838 1861 0.96

12 13 0.00021 0.014 15.8 5.9 1 23 1866 1888 1866 1888 0.98

13 13 0.03 1.9 9.0 8.2 1 23 1894 1916 1894 1917 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.052	3.4	8.3	0.2	1	23	1391	1414	1391	1414	0.94
2	13	4.7	3.1e+02	2.1	0.2	1	23	1582	1604	1582	1604	0.91
3	13	0.00019	0.012	16.0	2.7	2	23	1607	1628	1607	1628	0.97
4	13	7.3e-05	0.0047	17.3	0.2	3	23	1636	1656	1634	1656	0.98
5	13	6.1e-07	3.9e-05	23.8	4.1	2	23	1663	1684	1662	1684	0.97
6	13	5.7	3.7e+02	1.9	0.4	5	23	1697	1715	1695	1715	0.96
7	13	1.4	92	3.8	5.4	3	23	1722	1743	1720	1743	0.93
8	13	0.15	9.9	6.8	0.2	2	23	1754	1774	1753	1774	0.96
9	13	5.8e-05	0.0038	17.6	0.4	1	19	1780	1798	1780	1802	0.95
10	13	1.7e-05	0.0011	19.3	0.5	1	23	1810	1832	1810	1832	0.98
11	13	0.00011	0.0071	16.7	7.6	1	23	1838	1860	1838	1861	0.96
12	13	0.00021	0.014	15.8	5.9	1	23	1866	1888	1866	1888	0.98
13	13	0.03	1.9	9.0	8.2	1	23	1894	1916	1894	1917	0.95

Sequence Information

Coding Sequence: atggtGGACAGTGTGCAGTGCCCCGTGTGCACCTTGTATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCattgctggcaacaacaatggtggTCTGGACAGCGCCCTGGCGGCAGCTGTCATCTccagcagcagtcgctgcaGCGTTGCCTCAACCGAAAGCGTCGCCTCAACGCCGCCTGCTGTTGATGTCAAACCAGATGTGGCATCAGTaccaacagcgacagcaacacaACCGCCACAGCCACCACAACCACCCcaaccaacaccaccaccagcagcaacaacaacaacagcagcagcatcaacaacaacaagcacatcGCAATCAACAGCACCCAAAGCTGTCGCATTGCTggacaacaccagcagcagcagtagcaacaacagcagcagcaacaacaacaataacaacaaattgagcaaTCCACCGATTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCATAAGCAACGTGTCTGCTGTCTATCCGGCAACCCTGGCAACCGACTATCGCtacgaacagcagcaacagcaacagccacagctacagcagcagcaccagcagctgcatGGCTTTCCACgtggcaccaccaccacactGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAACCAACAGCCGCCTGCGCACTTTGcccatcagcaacagcagccgcagtcgaCCATGAAGTTCACGTATGCAACAGCGGCGTTGCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAGCCGACAGCAACGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCATAaccaaaacaagcaacaacaccaacaccaccaacaacagcaacagcaacaacaaccacaacacgTAAACGTACAGCAgcataatgcaaatgcagcaccACCGagtggcaaacaacaacacaatagCAAAATCCATGCGGATATCTTTCTGAatccaccgccaccgccacagCTCACAATTCCatcgtcggcgtcggcgtcggcgtcatcattgtcgttgtcgctgtccCTGTCGTCATCGACCTCCTCAAGACTGCAACATCCccaacagcaccaccaacaatcCCATGctgctagcagcagcagcagtagcagtagcagcagcaactatgcAGCAACCAGCTGCGCTCCCAGCTCCTCGGTTGCTCTGATGTCCGGCACATCGTCGGCACGCACCACCAGTCGCCAATCGAGCAATTCGCCCTTTGGTGCCCTGCTGAATGCGGCTGCGCACGCTGCCTGCTCCTCGCCCGCTTCGACTGGGGCGTCTGTGCTGCGCTATGCCGAGTCGCCAGTGGCCCACTATCTGGAGCGGGATAATGGTGATTTCATAGTGCAGGAGACGCCCAAACACATTGTGGAGTGTGTCGAGAAGGACGACGGTGAATTCTCCGTGATTGAACGCATCTATCAATCGCCACCCAGCGTTCTCCACAtacacgacgacgacgaagaggaggaggaggacgaggatgaTCAGCAGGGTTGGGCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGCCGAGTTGCACCCAAAACGACAACGAAAAAGTCACGCAAGACAAAATCGAGTGGCAGACTGCACAAGCGCGCCTCCAAGCAACAGCTGGCCACGACGACGGAGGACGAGGACGACTTCATGAGCATAGGCAGCAGTTGTGCCGAAAGCGAACATCATCCagaggagcagctgcagcaacagcagccgcagcaacagcatccgcAGCAATTAGCATCGGCTGGGGGGGCAGCCCAGTTGGCGGCGAGCTCATCGCCAGCTCAACTTTGCACTGCGCCCTCCACGAGCAGtggagctgttgttgctgctgctgctgccgccagtGGTGGTAAATTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGAGCCGCATTGGCGCAGCGCGTTCCTTTGCCGCTGTAGCGCCCATACCGCTCGTCAAGGTAGAAAAGGAGGAACCCATGGATGAATATGATGCCGTTGAGGTCGAGATGCAGTTGGAGCAAAAGCCGAGCCTAGAGCATGctagtggcagcagcagtagcagcagcagtagcagcaacagtagcagcagcagcagcagtggacaTGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGCGGCGAACGTTGCCGCCGAGGATCTCACACAGCCGCTACCGATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTTTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCAcagcgacggcaacggcgacgtcAACGACGAAAAAGACTGAGAacaacgctgctgctgttgctactggcagcaacagtggAAATTGCGCCGAATCCCATAGCATATCAGTGAATACGCCCGCCGAGCTTGTGCAGATCAAGAGCGAGAATGTGGAGGCGTCCACAtccagcagtggcagcatATTGGAAAAGCATCTGACTACCAGCTATGCGGCACAGCAGGCGGCACGCAAGCACTCCGCCGTCAACGATGACGATGCACGTGTCCTGCTGGAGTTTGCCAACTCCAAGCAGCTGCCGATGCCGGGCAATAGCAATCATACCACGTTTGTGGTGAACGCGGCCAGTTTTGCGTCAGCGGGTTCCGTATttgccagcggcaacagcagcagcggtggaAATGTGCAAAAGTCAACCAAGCCGGGCTGTGGCGATGAGTACATTCTGCCCGATGACACCAAACTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCAcctcgcagcagcaacagcagcatctccaacaacaaacacaacagcagcagcagcaacaacaacaatctttGCAGCAGGCGCAACCATCCGCTTTCACTGAGTTTAGTTTTCTGTACCAccaaaacacaacagcaacaacagcagcagcagcagcagcggcaacaacggcGACATCTACTACTTCCAACTTTGCACCGTTTGGcattcagcaacagcaacaacagttgcagttgcaacatcATCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCAACTCTTGCATCCTCGTCGAGCAATTCGTCTGTATTGGATCAGGAGTGCTCGATGAATGCCACGTTTCGCGTGGCAAAGCCACAATCAATGCTGGGCGCCTGGTATCAGCCACATCAGGCGCAGCATCAGGTGACATCTTCGCACAGTCCACAACATGTGGATCAGCCGAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGATAGCGATATGAGTGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACAgctgagcaacagcagcagccatatGCCCTCCGCTTCGACATCGACCACATCGTCATCGTTTGCTGCCGCAGCAACGGAGAGCAGTCTCGTCGGCGGCCTGGGTCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAGCAGGAAAGCAACTGCGACATAGAGAACTCTTGGAGTCAATCGATGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCACGACTACTATCCGGCGCAGGATCTcagtggccagcagcagcagcagcgagagcaAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCACAGCCGGGCGAGCTGGAAGCTTCCTCGAGCTCAACGAGAAACAATCATTTGTTGGATGCACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGCGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCTCAACGGAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACACTGTGTGGCCATCTTCGAGAAGCTAAAGGAGCGCAATGCGCACATGATTGGCGAGCACAACTATGTGCGCCAGAATCGGCGTCTCATCTGCACGCAGGCGCTGGCGATACTGACCCAGCCGCTGGCTCAGCAGCCAGAGCAGCAaatggagctggagctggagcagcagcagcatcagttgcTGCAGGTGGGCCACAGCACGGGCGGCGCCGAGCACGAAGATTCCAAGGATGGTATTGTGAAGATTAAGCAGGAACACTGTCAGGACAAGCACGATCCAGCATCGGAGCAATTGCTTGGCCACTTGGAGCTGCCGGATGTGAAGGATGCTGGCCTGCTCGAAGCCAGCGGTGAAAACGGACGCGATGCGGACATGAAGCCACCAACCACTGTTGCTGAGCTGGACGAAAAGCCGACCATAGCACCGCTGGCCATGACGACGCCCGCTGCCAAACTGGCTGCTCTTTATCGCATGCTAATTGCCTACAACGAATCGAAGCTGGGCCAGGAGCGCAACAATCTGAGCGAACTGGAGCAAAAGGCCATGGAGAAATCTATATTCTTGTGCTACATTTGCCGCACCGATTTCCCCTCTGTGAAGCTGTACGATGCGCATCTAACCGAGCATCCCGCCGAGTGTTTCACCTGTGGCAAGAAATTCTATCGCTGGAAGAACTTCTCGCTGCACCTGAAACGCCATCTGGGCTGGAAGGAGTTCGGCTGCTATGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCTCTCGTCGAGCACATGCGGATGCACACTGGCCAGACGCCACTCAAGTGCAAGATATGCGGCAAGAAGTTCAAGCGATACTCGAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTGTGCCACTGTGGCGAAGTGCTTCCATCAAAGGCGCGCTTCCTGTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCAAACTCGCTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTTGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATTAAGGCACACATGGCGACGCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGAACGGCCAAACCGTTCAAGTGCGAGTACTGCCCCAAGGCGTTCGTGCGCGAGTTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGTAACAAGAAGTTCACGTGCGACCAATGCGACAAGTCTTTCCATCGCCATTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAGCATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence: MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNNGGLDSALAAAVISSSSRCSVASTESVASTPPAVDVKPDVASVPTATATQPPQPPQPPQPTPPPAATTTTAAASTTTSTSQSTAPKAVALLDNTSSSSSNNSSSNNNNNNKLSNPPIKAVKSAPPTTEAPATTSNNNTPTISNVSAVYPATLATDYRYEQQQQQQPQLQQQHQQLHGFPRGTTTTLVIPQAPPQQHHNFLANQQPPAHFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTATQPHQKPPPAYGAAISQIRSQHNQNKQQHQHHQQQQQQQQPQHVNVQQHNANAAPPSGKQQHNSKIHADIFLNPPPPPQLTIPSSASASASSLSLSLSLSSSTSSRLQHPQQHHQQSHAASSSSSSSSSSNYAATSCAPSSSVALMSGTSSARTTSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEDEDDQQGWANSDEEDHVKVPHEHVEDGDDEHEDSRSRVAPKTTTKKSRKTKSSGRLHKRASKQQLATTTEDEDDFMSIGSSCAESEHHPEEQLQQQQPQQQHPQQLASAGGAAQLAASSSPAQLCTAPSTSSGAVVAAAAAASGGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARSFAAVAPIPLVKVEKEEPMDEYDAVEVEMQLEQKPSLEHASGSSSSSSSSSNSSSSSSSGHGTTSVIRMASTSAANVAAEDLTQPLPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATATSTTKKTENNAAAVATGSNSGNCAESHSISVNTPAELVQIKSENVEASTSSSGSILEKHLTTSYAAQQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGNSSSGGNVQKSTKPGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQHLQQQTQQQQQQQQQSLQQAQPSAFTEFSFLYHQNTTATTAAAAAAATTATSTTSNFAPFGIQQQQQQLQLQHHPQHGSSEATNAATLASSSSNSSVLDQECSMNATFRVAKPQSMLGAWYQPHQAQHQVTSSHSPQHVDQPSNFIAALSAVDCCSAAVDSDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQREQKRFDFNAVASEYAQPGELEASSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALAILTQPLAQQPEQQMELELEQQQHQLLQVGHSTGGAEHEDSKDGIVKIKQEHCQDKHDPASEQLLGHLELPDVKDAGLLEASGENGRDADMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00583141;
90% Identity: iTF_00564835;
80% Identity: -