Basic Information

Gene Symbol
-
Assembly
GCA_035043875.1
Location
JAWNMP010000312.1:22844592-22852494[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.052 3.4 8.3 0.2 1 23 1398 1421 1398 1421 0.94
2 13 4.7 3.1e+02 2.1 0.2 1 23 1591 1613 1591 1613 0.91
3 13 0.00019 0.012 16.0 2.7 2 23 1616 1637 1616 1637 0.97
4 13 7.3e-05 0.0047 17.3 0.2 3 23 1645 1665 1643 1665 0.98
5 13 6e-07 3.9e-05 23.8 4.1 2 23 1672 1693 1671 1693 0.97
6 13 5.7 3.7e+02 1.9 0.4 5 23 1706 1724 1704 1724 0.96
7 13 1.4 93 3.8 5.4 3 23 1731 1752 1729 1752 0.93
8 13 0.15 9.9 6.8 0.2 2 23 1763 1783 1762 1783 0.96
9 13 5.8e-05 0.0038 17.6 0.4 1 19 1789 1807 1789 1811 0.95
10 13 1.7e-05 0.0011 19.3 0.5 1 23 1819 1841 1819 1841 0.98
11 13 0.00011 0.0071 16.7 7.6 1 23 1847 1869 1847 1870 0.96
12 13 0.00021 0.014 15.8 5.9 1 23 1875 1897 1875 1897 0.98
13 13 0.03 2 9.0 8.2 1 23 1903 1925 1903 1926 0.95

Sequence Information

Coding Sequence
atggtGGACAGTGTGCAGTGCCCTGTGTGCACCTTATATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCATTGCTGTCAACAACAATGGTGGTCTGGACAGCGCCCTGGCGGCAGCTGTCATCTCCAGCAGCAGTCGCTGCAGCGTTGCCTCAACCGAAAGCGTCGCCTCAACGCCGCCTGCTGTTGATGTCAAACCGGATGTGGCATCAGTaccaacagcgacagcaacacaACTGCCACATCCACCACAACCACCCcaaccatcaccaccaccagcagcaacaacaacaacagcagcagcagcagcatcaacaacaacaagcacatcGCAATCAACAGCACCCAAGGCTGTCGCATTGCTGGacaacgccagcagcagcagtagcaacaacagcagcagcaacaacaacaacaacaacaacaaattgagcaATCCACCGATTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCATAAGCAACGTGTCTGCTGTCTATCCGGCAAACCTGGCAACCGACTATCGCtacgaacagcagcaacagccacaggtacagcagcagcaccagcagctgcaTGGCTTTCCACGTGGCATCACCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAACCAACAGCCGCCTGCGCACTTTgcccaccagcaacagcagccgcagtcgaCCATGAAGTTCACgtatgcaacagcagcgttGCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAGCCGACGACAACGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCataaccaaaacaaacaacaacaccaacaccaccaacaacaacaacaacagcaaccacaacccATAAGCGTACATCAGCataatgcaaatgcagcaCCACCGagtggcaaacaacaacacaatagCAAAATCCATGCGGATATCTTTCTGAatccaccgccaccgccacagCTCACAATTCCAtcgtcggcgtcggcgtcatcgttgtcgttgtcgctgtccCTGTCGTCATCGACCTCCTCAAGACTGCAACATCCCcaacagcaccaccaacaaTCTCATgcagctagcagcagcagcagcagtagcagcagcaactatgCAGCAACCAGCTGCGCTCCCAGCTCCTCGGTTGCTCTGATGTCCGCCACATCGTCGGCACGCGCTAGCAGTCGCCAGTCGAGCAATTCACCCTTTGGTGCCCTGCTGAATGCGGCTGCGCACGCTGCCTGCTCCTCGCCCGCTTCGACAGGGGCGTCTGTGCTGCGCTATGCCGAGTCGCCAGTGGCCCACTATCTGGAGCGGGATAATGGTGATTTCATAGTGCAGGAGACGCCCAAGCACATTGTGGAATGTGTCGAGAAAGACGACGGTGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTCCACAtacacgacgacgacgaagaggAGGGGGAGGACGAGGATGATCAGCAGGGttGGCCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGCCGAGTTGCACCCAAAACGACAACGAAAAAGTCACGCAAGACAAAATCGAGTGGCAGATTGCACAAGCGCGGCTCCAAGCATCAGCTGACCACGACCACGGAGGACGAGGATGACTTCATGAGCATAGGTAGCAGTTGTGCCGAAAGCGAGCATATTCCagaggagcagctgcagcaacagcagccgcagcaacagcatccgCTGCAATTAGCACGCAATCCGCAACAATTAGCATCCGCTGGGGGGGCAGCACAGTTGGCGGCAAGCTCATCGCCAGCTCAACTTTGCACTGCGCCCTCCACGAGCAgtggagctgctgttgctgctgcagccgccgTCGGCAGTGGTGGCAAATTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGAGTCGCATTGGCGCAGCGCGTCCCTTTGCCGCTGTAGCGCCCATACCGCTCGTCAAGGTGGAAAAGGAGGAACCCATGGATGAATATGATGCCGTTGAGGTCGAGATGCAGTTGGAGCAAAAGCCCAGCCTAGAGCATGCCAGCGGCAGcatcagtagcagcagcagtagcagcaacagtagcagcagcagcagcagcagtggacaTGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGCGGCGAACGTTGCCGCCGAGGATCTCACACAGCCGCCGCCGATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTCTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCACAGCGACAGCAACGGCGACGTCAACGACGAAAAAGACTGAGAacaacgctgctgctgttgctactggcagcaacagtagcaattGCGCCGAATCGCATAGCATATCAGTGAATACGCCCGCCGAGCTTGTGCAGATCAAGAGCGAGAACGTGGAGGCGTCCACATCCAGCAGTGGCAGCATATTGGAAAAGCATCTGACTACCAGCTATGCGGCACAGCAGGCGGCACGCAAGCACTCCGCCGTCAACGATGACGATGCACGTGTCCTGCTCGAGTTTGCCAACTCGAAGCAGCTTCCGATGCCGGGGAACAGCAATCATACCACGTTTGTGGTGAACGCGGCCAGTTTTGCGTCAGCGGGTTCCGTATttgccagcggcagcagcagcagcggtgtCAATGTGCAAAAGTCAACCAAGCCGGGCTGTGGCGATGAGTACATTCTGCCCGATGACACCAAGCTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCGTCCAcctcgcagcagcaacagcagcatctgcaacaacaaacacaacagcagcaacaacaacaatctttGCAGCAGGCGCAACCATCCGCCTTCACTGAGTTTAGTTTTCTGTACcaccaaaacacaacaacaccaacagcagctgtagcagcaacggcagcggcaacaacagcgacatcTACTACTTCCAACTTTGCACCGTTTGGCattcagcaacagcaacaacagttgcagttgcaacatcATCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCAACGCTTGCATCCTCGTCGAGCAATTCGTCTGCATTGGACCAGGAGTGCTCGATGAATGCCACGTTTCGGGTGGCAAAGCCACAATCAATGCTGGGCGCCTGGTATCAGCCGCATCAGGCGCAGCATCAGGTGACATCTTCGCACAGTCCACAACATGTGGATCAGCCGAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGATAGCGAGATGAGTGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACAgctgagcaacagcagcagtcataTGCCATCCGCTTCAACATCGACCACATCGTCATCGTTTGCTGCCGCAGCAACGGAGAGCAGTCTCGTCGGTGGCCTGGGTCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAGCAGGAAAGCAACTGCGACATAGAGAACTCTTGGAGTCAATCGatGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCACGACTATTATCCGGCGCAGGATCTCagtggccagcagcagcagcagcagcgagagcAAAAACGATTTGACTTCAATGCGATCGCCTCGGAGTACGCACAGCCGGGCGAGCTGGAAGCTTCCTCGAGCTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCTTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGCGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCTCAGCGAAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACACTGTGTGGCCATCTTCGAGAAGCTAAAGGAGCGCAATGCGCACATGATTGGCGAGCACAACTATGTGCGCCAGAATCGGCGTCTCATCTGCACGCAGGCGCTGGTCAGCGCTGCGATGCTCGCCCAGCCGCTGGCTCAGCAGTCAGAGCAGCAAatggagctggagcagcagcaacagcatcagttGTTGCAGGTGAGCCACAGCACAGGCGGTGCCGAGCACGAGGATTCCAAGGATGGTATTGTGAAGATTAAGCAGGAACACTGTCAGGACAAGCACGATCCAGCATCGGAGCAATTGCTTGGCCACTTGGAGCTGCCGGATGTGAAGGATGCTggcctgctcgaagccagcgGTGAAAACGGACGCGATGCGGACATGAAGCCACCAACCACTGTTGCTGAGCTGGACGAGAAACCGACCATAGCACCGCTGGCCATGACGACACCCGCTGCCAAACTGGCTGCTCTTTATCGCATGTTAATTTCCTACAACGAATCGAAGCTGGGCCAGGAGCGCAACAATTTGAGCGAACTGGAGCAAAAGGCCATGGAGAAATCTATATTCTTGTGCTACATTTGTCGCACCGATTTCCCCTCTGTGAAGCTGTACGATGCGCATCTAACCGAGCATCCCGCCGAGTGTTTCACTTGCGGCAAGAAATTCTATCGCTGGAAGAACTTCTCGCTGCACCTGAAACGCCATCTGGGCTGGAAGGAGTTCGGCTGCTATGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCTCTCGTCGAGCACATGCGGATGCACACTGGCCAGACGCCACTCAAGTGCAAAATATGCGGCAAGAAGTTCAAGCGATATTCGAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTGTGCCACTGTGGCGAAGTGCTGCCCTCAAAGGCGCGCTTCCTTTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCGAACTCGCTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTCGACTATGCCGAGCCGATGGAGTGTCCTATGTGCAAACAGATCTTTGCCAAGACATCGATTAAGGCTCACATGGCGACGCATTCGACGGATCCGCAATACGATTGCGCCATCTGCAATAAGAGCTTCTCCACCAAATGGAACCTCAAGATACACTCGTGGGTGCATGCGAATCGAACGGCCAAACCGTTCAAGTGCGAGTACTGCCCCAAGGCGTTTGTGCGCGAGTTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGCAACAAGAAGTTCACGTGCGATCAATGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAACATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAVNNNGGLDSALAAAVISSSSRCSVASTESVASTPPAVDVKPDVASVPTATATQLPHPPQPPQPSPPPAATTTTAAAAASTTTSTSQSTAPKAVALLDNASSSSSNNSSSNNNNNNNKLSNPPIKAVKSAPPTTEAPATTSNNNTPTISNVSAVYPANLATDYRYEQQQQPQVQQQHQQLHGFPRGITTTLVIPQAPPQQHHNFLANQQPPAHFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTTTQPHQKPPPAYGAAISQIRSQHNQNKQQHQHHQQQQQQQPQPISVHQHNANAAPPSGKQQHNSKIHADIFLNPPPPPQLTIPSSASASSLSLSLSLSSSTSSRLQHPQQHHQQSHAASSSSSSSSSNYAATSCAPSSSVALMSATSSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEGEDEDDQQGWPNSDEEDHVKVPHEHVEDGDDEHEDSRSRVAPKTTTKKSRKTKSSGRLHKRGSKHQLTTTTEDEDDFMSIGSSCAESEHIPEEQLQQQQPQQQHPLQLARNPQQLASAGGAAQLAASSSPAQLCTAPSTSSGAAVAAAAAVGSGGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPMDEYDAVEVEMQLEQKPSLEHASGSISSSSSSSNSSSSSSSSGHGTTSVIRMASTSAANVAAEDLTQPPPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATATSTTKKTENNAAAVATGSNSSNCAESHSISVNTPAELVQIKSENVEASTSSSGSILEKHLTTSYAAQQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGSSSSGVNVQKSTKPGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQHLQQQTQQQQQQQSLQQAQPSAFTEFSFLYHQNTTTPTAAVAATAAATTATSTTSNFAPFGIQQQQQQLQLQHHPQHGSSEATNAATLASSSSNSSALDQECSMNATFRVAKPQSMLGAWYQPHQAQHQVTSSHSPQHVDQPSNFIAALSAVDCCSAAVDSEMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQQREQKRFDFNAIASEYAQPGELEASSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVSAAMLAQPLAQQSEQQMELEQQQQHQLLQVSHSTGGAEHEDSKDGIVKIKQEHCQDKHDPASEQLLGHLELPDVKDAGLLEASGENGRDADMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLISYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
-