Dpic006175.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila picticornis
Gene Symbol
-
Assembly
GCA_035043845.1
Location
JAWNMR010000362.1:17913163-17919698[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.18 11 6.6 0.2 1 23 1385 1408 1385 1408 0.92
2 13 4.7 2.9e+02 2.1 0.2 1 23 1578 1600 1578 1600 0.91
3 13 0.00019 0.012 16.0 2.7 2 23 1603 1624 1603 1624 0.97
4 13 7.2e-05 0.0044 17.3 0.2 3 23 1632 1652 1630 1652 0.98
5 13 6e-07 3.7e-05 23.8 4.1 2 23 1659 1680 1658 1680 0.97
6 13 5.7 3.5e+02 1.9 0.4 5 23 1693 1711 1691 1711 0.96
7 13 1.4 87 3.8 5.4 3 23 1718 1739 1716 1739 0.93
8 13 0.15 9.3 6.8 0.2 2 23 1750 1770 1749 1770 0.96
9 13 5.7e-05 0.0035 17.6 0.4 1 19 1776 1794 1776 1798 0.95
10 13 1.6e-05 0.001 19.3 0.5 1 23 1806 1828 1806 1828 0.98
11 13 0.00011 0.0066 16.7 7.6 1 23 1834 1856 1834 1857 0.96
12 13 0.00021 0.013 15.8 5.9 1 23 1862 1884 1862 1884 0.98
13 13 0.03 1.8 9.0 8.2 1 23 1890 1912 1890 1913 0.95

Sequence Information

Coding Sequence
ATGGTGGACAGCGTGCAGTGTCCCGTGTGCACCTTGTATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCattgctggcaacaacaacggtggTCTGGACAGCGCCCTGGCGGCAGCTGTCATCTCCAGCAGCAGTCGCTGCAGCGTTGCCTCTACCGAAAGCGTCGTCTCAACGCCGCCTGCTGTTGATGTCAAACCAGATGTGGCATCAGTaccaacagcgacagcaacacaACCGCCACAGCCACCACAACCACcccaaccaccaccaccagcaacaacaataacaacagcagcagcagcagcaccatcaacaacaagcacatcGCAATCAACAGCACCCAAGGCTGTGGCAGTGCTGGagaatgccagcagcagcagtagcaacaacagcagcagcaacaacaacaataacaacaacaacaaattgagcaATCCACCGATTAAGGCTGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCATAAGCAACGTGTCTGCTGTCTATCCGGCAACCCTGGCAACCGACTATCGctacgagcagcagcaacagccacagctacagcagcagcaccagcagctgcaCGGCTTTCCACGTGGCACCACCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAGCCAACAGCCGCCTGCGCACTTTgcccaccagcagcagcagccgcagtcgaCCATGAAGTTCACgtatgcaacagcagcgttgCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAGCCGACGGCAACACAGCCACATCAGAAGCCTCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCATAaccaaaacaagcaacaacaccaacaccaccaacaacagcaacagcaaccacaacacaTAAGCGTACAGCAgcataatgcaaatgcagcaccACCGagtggcaaacaacaacacaatagCAAAATCCATGCGGATATCTTTCTGAATCTACCGCCACCGCCACAGCTCACAACTCCATCGTCGGCGTCGacgtcatcgttgtcgttgtcgctgtccCTGTCGTCATCGACATCCTCAAGACTGCAACATCCCcaacagcaccaccaacaatcCCATGctgctagcagcagcagcagtagcagcagcaactatgcAGCAACCAGTTGCGCTCCGAGCTCCTCGGTTGCTCTGATGTCCGGCACATCGTCGGCACGCGCCAGCAGTCGCCAGTCGAGCAATTCGCCCTTTGGTGCCCTGCTGAATGCGGCTGCGCACGCTGCCTGCTCCTCGCCTGCTTCGACTGGGGCGTCTGTGCTGCGCTATGCTGAGTCACCAGTGGCTCACTATCTTGAGCGGGATAATGGTGATTTCATAGTGCAGGAGACGCCCAAACACATTGTGGAGTGTGTCGAGAAAGAAGACGGTGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTCCACAtacacgacgacgacgaagaggaggaggaggacgaggatgATCAGCAGGGtTGGGCAAACAGCGATGAGGAAGATCACATCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCATGAGGATAGCCGCAGCCGAGTTGCACCCAAAACGACAACGAAAAAGTCACGCAAGACAAAATCGAGTAGCAGATTGCACAAGCGCGCCTCCAAGCATCAGCTGGCCACGACAACGGAGGACGAGGACGACTTCATGAGCATAGGCAGCAGTTGTGCCGAAAGCGAGCATCATCCagaggagcagctgcagcaacagcagccgcagcaacagcatccgcAGCAACTAGCATCGGCTGGGGGGGCAGCAAAGTTGGCGGCGAGCTCATCGCCAGCTCAACTTTGCACTGCGCCCTCCACGAGCAGTGgagcggctgctgcttctgccgcCAGTGGTGGTAAATTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGAGTCGCATTGGCGCAGCGCGTCCCTTTGCCGCTGTAGCACCCATACCGCTCGTCAAGGTGGAAAAGGAGGAACCCATGGATGAATATGATGCCGTTGAGGTCGAGATGCAGTTGGAGCAAAAGCCGAGCCTAGAGCAtgcaagcggcagcagcagtagcagcagcagtaacagcaacagtagcagcagtagcagcagcagtggacaTGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGCGGCGAACGTTGCCGCCGAGGATCTCACACAGCCGCCGCCGATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTCTCGGCGCCTGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCacagcgacggcaacggcgacgtcAACGACGAAAAAGACTGAGAacaacgctgctgctgttgccactggcagcaacagtagcaattGCGCCGAATCCCATAGCATATCAGTGAATACGCCCGCCGAGCTTGTGCAGATCAAGAGCGAGAATGTGGAGGTGTCCACAtccagcagtggcagcataTTGGAAAAGCATCTGACTACCAGCTATGCGGCACAGCAGGCGGCACGCAAACACTCCGCCGTCAACGATGACGATGCACGTGTCCTGCTCGAGTTTGCCAACTCGAAGCAGCTGCCGATGCCGGGCAATAGCAATCAAACCACGTTTGTGGTGAACGCAGCCAGTTTTGCGTCAGCGGGTTCTGTATttgccagcggcagcagcagtagtggtGTCAATGTGCAAAAGTCAACCAAACCGGGCTGTGGCGATGAGTACATTCTGCCCGACGACACCAAACTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCAcctcgcagcagcaacagcagcatctccaacaacaaacacaacagcagcagcagcaacaacaatcttTGCAGCAGGCGCAACCATCCGCCTTCACTGAGTTTAGTTTTCTGTACcaccaaaacacaacaacaacaacagcagcagctgcagcagcagcagcagaaacggCGACATCTACTACTTCCAACTTTGCACCTTTTGGcattcagcaacaacaacaacagttgcagttgcaacatcATCCGCAGAATGGGTCCAGCGAGGCAACCAATGCCGCAACGCTTGCATCCTCGTCGAGCAATTCGTCTGAATTGGACCAGGAATGCTCGATGAATGCCACGTTTCGCGTGGCAAAGCCACAATCAATGCTGGGCGCCTGGTATCAGCCACATCAGGCGCAGCATCAGGTGACATCTTCACACAGTCCACAACATGTGGATCAGCCGAGCAATTTCATTGCGGCTCTGTCTGCCGTTGACTGCTGCAGTGCAGCCGTCGATAGCGATATGAGTGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACAgctgagcaacagcagcagccatatGCCCTCCGCTTCGACATCGACCACATCGTCATCGTTTGCTGCCGCAGCAACGGAGAGCAGTCTCGTCGGTGGCCTGGGTTTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAGCAGGAAAGCAACTGCGACATAGAGAACTCTTGGAGTCAATCGaTGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCACGACTACTATCCGGCGCAGGATCTcagtggccagcagcagcagcagcgagagcAAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCACAGCCGGGCGAGCTGGAAGCTTCCTCGAGCTCAACAAGAAACAATCATTTGTTGGATACACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGCGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCACTGGCTCAACGGAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACACTGTGTGGCCATCTTCGAGAAGCTAAAGGAGCGCAATGCGCACTTGATTGGCGAGCACAACTATGTGCGCCAGAATCGGCGTCTCATCTGCACGCAGGCGCTGGTCAGCACTGCAATGCTCTCCCAGCCGCTGGCTCAGCAGCCAGAGCAGCAaatggagctggagcagcagcaacatcatcagttGCTGCAGGTAAGCCACAGCACGGGCGGCGCCGAGCACGAGGATTCCAAGGATGGTATTGTCAAGATTAAGCAGGAACACTGTCAGGAGAAGCACGATCCAGCATCGGAGCAATTGCTTGGCCACATGGAACTGCCGGATGTGAAGGATGCTGGCCTGCTCCAAGCCAGCGGTGAAAGCGGACGCGATGCGGACATGAAGCCACCAACCACTGTTGCTGAGCTGGACGAGAAACCGACTATAGCACCGCTGGCCATGACGACGCCCGCTGCCAAACTAGCTGCTCTTTATCGAATGCTAATTGCCTACAACGAATCGAAGCTGGGCCAGGAGCGCAACAATCTGAGCGAACTGGAGCAAAAGGCCATGGAGAAATCTATATTCTTGTGCTACATTTGCCGTACCGATTTCCCCTCTGTAAAGCTGTACGATGCGCATCTAACCGAGCATCCCGCCGAGTGTTTCACTTGCGGCAAGAAATTCTATCGCTGGAAGAACTTCTCGCTGCACCTGAAACGCCATCTGGGCTGGAAGGAGTTCGGCTGCTACGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCTCTTGTCGAGCACATGCGGATGCACACTGGCCAGACGCCACTCAAGTGCAAGATATGCGGCAAGAAATTCAAGCGATACTCGAACTTGACGCAGCATCGCAAGCGTCACACTAAGATGACGGTGCGCAAAAAGGAATACGTTTGCCACTGTGGCGAAGTGCTGCCCTCAAAGGCGCGCTTCCTGTGGCACAAGGAGACACACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTTGTGCATGCGAACTCGCTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTCGATTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATTAAGGCGCACATGGCGACGCACTCGACGGATCCACAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCACGCAAATCGAACGGCCAAACCGTTCAAGTGCGAGTACTGCCCCAAGGCGTTCGTGCGCGAATTGGACTTCAAGAATCACATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAATACAACTATATGCGGCATAGGCGGGAGCATCATGGCAAAAAGAAGTTCACGTGCGATCAATGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGGAAGAGCTCCACCACAAAGACCAATCACAACAAGCATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNNGGLDSALAAAVISSSSRCSVASTESVVSTPPAVDVKPDVASVPTATATQPPQPPQPPQPPPPATTITTAAAAAPSTTSTSQSTAPKAVAVLENASSSSSNNSSSNNNNNNNNKLSNPPIKAVKSAPPTTEAPATTSNNNTPTISNVSAVYPATLATDYRYEQQQQPQLQQQHQQLHGFPRGTTTTLVIPQAPPQQHHNFLASQQPPAHFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTATQPHQKPPPAYGAAISQIRSQHNQNKQQHQHHQQQQQQPQHISVQQHNANAAPPSGKQQHNSKIHADIFLNLPPPPQLTTPSSASTSSLSLSLSLSSSTSSRLQHPQQHHQQSHAASSSSSSSSNYAATSCAPSSSVALMSGTSSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEEEEEDEDDQQGWANSDEEDHIKVPHEHVEDGDDEHEDSRSRVAPKTTTKKSRKTKSSSRLHKRASKHQLATTTEDEDDFMSIGSSCAESEHHPEEQLQQQQPQQQHPQQLASAGGAAKLAASSSPAQLCTAPSTSSGAAAASAASGGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPMDEYDAVEVEMQLEQKPSLEHASGSSSSSSSNSNSSSSSSSSGHGTTSVIRMASTSAANVAAEDLTQPPPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATATSTTKKTENNAAAVATGSNSSNCAESHSISVNTPAELVQIKSENVEVSTSSSGSILEKHLTTSYAAQQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNQTTFVVNAASFASAGSVFASGSSSSGVNVQKSTKPGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQHLQQQTQQQQQQQQSLQQAQPSAFTEFSFLYHQNTTTTTAAAAAAAAETATSTTSNFAPFGIQQQQQQLQLQHHPQNGSSEATNAATLASSSSNSSELDQECSMNATFRVAKPQSMLGAWYQPHQAQHQVTSSHSPQHVDQPSNFIAALSAVDCCSAAVDSDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQREQKRFDFNAVASEYAQPGELEASSSSTRNNHLLDTQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHLIGEHNYVRQNRRLICTQALVSTAMLSQPLAQQPEQQMELEQQQHHQLLQVSHSTGGAEHEDSKDGIVKIKQEHCQEKHDPASEQLLGHMELPDVKDAGLLQASGESGRDADMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGKKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
-