Deng007011.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila engyochracea
Gene Symbol
-
Assembly
GCA_035042385.1
Location
JAWNLK010000101.1:14790765-14797346[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.05 3.2 8.3 0.2 1 23 1391 1414 1391 1414 0.94
2 13 4.6 2.9e+02 2.1 0.2 1 23 1584 1606 1584 1606 0.91
3 13 0.00018 0.012 16.0 2.7 2 23 1609 1630 1609 1630 0.97
4 13 7e-05 0.0045 17.3 0.2 3 23 1638 1658 1636 1658 0.98
5 13 5.9e-07 3.7e-05 23.8 4.1 2 23 1665 1686 1664 1686 0.97
6 13 5.5 3.5e+02 1.9 0.4 5 23 1699 1717 1697 1717 0.96
7 13 1.4 87 3.8 5.4 3 23 1724 1745 1722 1745 0.93
8 13 0.15 9.3 6.8 0.2 2 23 1756 1776 1755 1776 0.96
9 13 5.6e-05 0.0035 17.6 0.4 1 19 1782 1800 1782 1804 0.95
10 13 1.6e-05 0.001 19.3 0.5 1 23 1812 1834 1812 1834 0.98
11 13 0.00011 0.0067 16.7 7.6 1 23 1840 1862 1840 1863 0.96
12 13 0.0002 0.013 15.8 5.9 1 23 1868 1890 1868 1890 0.98
13 13 0.029 1.8 9.0 8.2 1 23 1896 1918 1896 1919 0.95

Sequence Information

Coding Sequence
atggtGGACAGTGTGCAGTGCCCCGTGTGCACCTTGTATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCattgctggcaacaacaatggtggTCTGGACAGCGCCCTGGCGGCAGCTGTCATCTccagcagcagtcgctgcAGCGTTGCCTCAATCGAAAGCGTCGCCTCAACGCCGCCTGCTGTTGGTGTCAAACCGGATGTGGCATCAGTaccaacagcgacagcaacacaACCGCCACAGCCACCACAACCACCCcaaccaccaacaccagcagcagcagcaacaacaacagcaggagcagtagcatcaacaacaagcacatcGCAATCAACAGCACCCAAGGCTGTCGCATTGCTGgacaacgccagcagcagcagtagcaacaacagcagcagcagcagcagcaacagcagcaacaacaacaacaacaacaacaacaaattgagcaaTCCACCGACTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCATAAGCAACGTGTCTGCTGTCTATCCGGCAACCCTGGCAACCGACTATCGCtacgaacagcagcaacagccacagcttcagcagcagcaccagcagctgcaTGGCTTTCCACGTGGCACCACCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAACCAACAGCCGCCTGCGCACTTTgcccaccagcaacagcagccgcagtcgaCCATGAAGTTCACgtatgcaacagcagcgttgCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAGCCGACGGCAACGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCATAaccaaaacaagcaacaacaccaccaacaacagcaaccacaacacaTAAGCGTACAGCAGcataatgcaaatgcagcaccACCGagtggcaaacaacaacacaatggCAAAATCCATGGGGATATCTTTCTGAatccaccgccaccgccacagCTCACAATTCCATCGTCGGcgtcatcgttgtcgttgtcgctgtccCTGTCGTCATCGACCTCCTCAAGACTGCAACATCCccaacagcaccaccaacaatCCCATGCggctagcagcagcagcagtagcagtagcaacagcaactatgCAGCAACCAGCTGCGCTTCCAGCTCCTCGGTTGCTCTGATGTCCGGCACATCGTCAGCACGCGCCAGCAGTCGCCAGTCGAGCAATTCACCCTTTGGTGCCCTGCTGAATGCGGCTGCGCACGCTGCCTGCTCCTCGCCCGCTTCAACTGGGGCGTCTGTGCTGCGCTATGCCGAGTCGCCAGTGGCCCACTATCTGGAGCGGGATAACGGTGATTTCATAGTGCAGGAGACGCCCAAGCACATTGTGGAGTGTGTCGAGAAAGACGACGGTGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTCCACAtacacgacgacgacgaagaggaggaggaggacgaggaTGATCAGCAGGGTTGGGCGAACAGCGATGAGGAAGATCACGTCAAGGTGCCGCACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGCCGAGTTGCACCCAAAACGACAACGAAAAAGTCACGCAAGACAAAATCGAGTAGCAGATTGCACAAGCGCGCCTCCAAGCATCAGCTGGCCACGACGACGGAGGACGAGGACGACTTCATGAGCATAGGCAGCAGTTGTGCCGAAAGCGATCATCATCCagaggagcagctgcagcaacagcagccgcagcaacagcatccgcAGCAATTAGCATCGGCTGGGGGGGCAGCACAGTTGGCGGCGAGCTCATCGCCGGCTCAACTTTGCACTGCGCCCTCCACGAGCAgtggagctgctgttgctgctgctgctgccgccgccagtGGTGGTAAAGTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGACTCGCATTGGCGCAGCGCGTCCCTTTGCCGCTGTAGCGCCCATACCGCTCGTCAAGGTGGAAAAGGAGGAACCCATGGATGAATATGATGCCGTTGAGGTCGAGATGCAGTTGGAGCAAAAGCCCAGCCTAGAGCATGctagcggcagcagcagtagcagcagcagtagcagcaacagtagcagcagcagcagcagcagtggacaTGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGCGGCGAACGTGGCCGCCGAGGATCTCACACAGCCGCCGCCGATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTCTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCacagcgacggcaacggcgacgtcAACGACGAAAAAGACTGAGAacaacgctgctgctgttgctactggcagcaacagtagcaattGCGCCGAATCCCATAGCATATCAGTGAATACGCCCGCCGAGCTTGTGCAGATCAAGAGCGAGAACGTGGAGGCGTCCACATCGAGCAGTGGCAGCATATTGGAAAAGCATCTGACAACCAGCTATGCGGCACAGCAGGCGGCACGCAAGCACTCCGCCGTCAACGATGACGATGCACGTGTCCTGCTCGAGTTTGCCAACTCGAAGCAGCTGCCGATGCCGGGCAACAGCAATCATACCACGTTTGTGGTGAACGCAGCCAGTTTTGCGTCAGCGGGTTCCGTATttgccagcggcagcagcagcagcggtgtcAATGTGCAAAAGTCAACCAAGCCGGGCTGTGGCGATGAGTACATTCTGCCCGATGACACCAAGCTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCAcctcgcagcagcaacagcagcatctccaacaacaaacacaacagcagcagcagcagcaacaacaatctttGCAGCAGGCGCAACCATCCGCCTTCACTGAGTTTAGTTTTCTGTACcaccaaaacacaacaacaacaacagcagctgcagcggcagcggcagcggcaacaacggcGACATCTACTACTTCCAACTTTACACCGTTTGGCattcagcaacagcaacaacagttgcagttgcaacatcATCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCAACGCTTGCATCCTCGTCGAGCAATTCGTCTGCATTGGACCAGGAGTGCTCGATGAATGCCACGTTTCGCGTGGCAAAGCCACAATCAATGCTGGGCGCCTGGTATCAGCCACATCAGGCGCAGCATCAGGTGACATCTTCGCACAGTCCACAAAATGTGGATCAGCCGAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGATAGCGATATGAGCGAAGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACAgctgagcaacagcagcagtcataTGCCATCCGCTTCGACATCGACCACATCGTCATCGTTTGCTGCCGCAACAACGGAGAGCAGTCTCGTCGGTGGCCTGGGTCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAACAGGAAAGCAACTGCGACATTGAGAACTCTTGGAGTCAATCGatGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCACGACTATTATCCGGCGCAGGATCTCagtggccagcagcagcagcgagagcAAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCACAGCCGGGCGAGCTGGAAGCTTCATCGAGCTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGCGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCTCAACGGAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACATTGTGTGGCCATCTTCGAGAAGCTAAAGGAGCGCAATGCGCACATGATTGGCGAGCACAACTATGTGCGCCAGAATCGGCGTCTCATCTGCACGCAGGCGCTGGTCAGCGCTGCGATGCTCGCCCAGCCGCTGGCTCAGCAGTCAGAGCAGCATATGGAGctggagcaacaacaacagcatcagttGCTGCAGATGAGCCACAGCACGGGCGGCGCCGAGCACGAGGATTCTAAGGATGGTATTGTGAAGATTAAGCAGGAACATTGTCACGACAAGCACGATCCAGCATCGGAGCAATTGCTTGGCCACTTGGAGCTACCGGATGTGAAGGATGCTGGCCTGCTCGAAACCAGTGGTGACAACGGACGCGATTCGGATATGAAGCCACCAACCACTGTTGCTGAGCTTGACGAGAAACCGACCATAGCACCACTGGCCATGACGACGCCCGCTGCCAAACTGGCTGCTCTTTATCGCATGCTAATTGCCTACAACGAATCGAAGCTGGGTCAGGAGCGCAACAATCTAAGTGAACTGGAGCAAAAGGCCATGGAGAAATCTATATTCTTGTGCTACATTTGCCGCACCGATTTTCCCTCTGTGAAGCTGTACGATGCGCATCTAACCGAGCATCCCGCCGAGTGTTTCACTTGCGGCAAGAAATTCTATCGCTGGAAGAACTTCTCGCTGCACCTGAAACGCCATCTGGGCTGGAAGGAGTTTGGCTGCTATGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCTCTCGTCGAGCACATGAGGATGCACACTGGCCAGACGCCACTCAAGTGCAAGATATGCGGCAAGAAGTTCAAGCGATACTCAAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAGAAGGAATATGTGTGCCACTGTGGCGAAGTGCTGCCCTCAAAGGCCCGCTTCCTGTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCGAACTCGCTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTCGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATTAAGGCGCACATGGCGACGCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGAACGGCCAAACCGTTCAAGTGCGAGTACTGCCCGAAGGCGTTTGTGCGCGAGCTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGCAACAAGAAGTTCACGTGCGATCAATGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAAAGCTCCACCACAAAGACCAATCACAACAAACATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNNGGLDSALAAAVISSSSRCSVASIESVASTPPAVGVKPDVASVPTATATQPPQPPQPPQPPTPAAAATTTAGAVASTTSTSQSTAPKAVALLDNASSSSSNNSSSSSSNSSNNNNNNNNKLSNPPTKAVKSAPPTTEAPATTSNNNTPTISNVSAVYPATLATDYRYEQQQQPQLQQQHQQLHGFPRGTTTTLVIPQAPPQQHHNFLANQQPPAHFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTATQPHQKPPPAYGAAISQIRSQHNQNKQQHHQQQQPQHISVQQHNANAAPPSGKQQHNGKIHGDIFLNPPPPPQLTIPSSASSLSLSLSLSSSTSSRLQHPQQHHQQSHAASSSSSSSSNSNYAATSCASSSSVALMSGTSSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEDEDDQQGWANSDEEDHVKVPHEHVEDGDDEHEDSRSRVAPKTTTKKSRKTKSSSRLHKRASKHQLATTTEDEDDFMSIGSSCAESDHHPEEQLQQQQPQQQHPQQLASAGGAAQLAASSSPAQLCTAPSTSSGAAVAAAAAAASGGKVMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASTRIGAARPFAAVAPIPLVKVEKEEPMDEYDAVEVEMQLEQKPSLEHASGSSSSSSSSSNSSSSSSSSGHGTTSVIRMASTSAANVAAEDLTQPPPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATATSTTKKTENNAAAVATGSNSSNCAESHSISVNTPAELVQIKSENVEASTSSSGSILEKHLTTSYAAQQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGSSSSGVNVQKSTKPGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQHLQQQTQQQQQQQQQSLQQAQPSAFTEFSFLYHQNTTTTTAAAAAAAAATTATSTTSNFTPFGIQQQQQQLQLQHHPQHGSSEATNAATLASSSSNSSALDQECSMNATFRVAKPQSMLGAWYQPHQAQHQVTSSHSPQNVDQPSNFIAALSAVDCCSAAVDSDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAATTESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQREQKRFDFNAVASEYAQPGELEASSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVSAAMLAQPLAQQSEQHMELEQQQQHQLLQMSHSTGGAEHEDSKDGIVKIKQEHCHDKHDPASEQLLGHLELPDVKDAGLLETSGDNGRDSDMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
-