Dgla007115.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila glabriapex
Gene Symbol
-
Assembly
GCA_035042305.1
Location
JAWNLN010000060.1:6911801-6918344[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.051 3.2 8.3 0.2 1 23 1392 1415 1392 1415 0.94
2 13 4.6 2.9e+02 2.1 0.2 1 23 1585 1607 1585 1607 0.91
3 13 0.00018 0.012 16.0 2.7 2 23 1610 1631 1610 1631 0.97
4 13 7.1e-05 0.0044 17.3 0.2 3 23 1639 1659 1637 1659 0.98
5 13 5.9e-07 3.7e-05 23.8 4.1 2 23 1666 1687 1665 1687 0.97
6 13 5.6 3.5e+02 1.9 0.4 5 23 1700 1718 1698 1718 0.96
7 13 1.4 87 3.8 5.4 3 23 1725 1746 1723 1746 0.93
8 13 0.15 9.3 6.8 0.2 2 23 1757 1777 1756 1777 0.96
9 13 5.7e-05 0.0035 17.6 0.4 1 19 1783 1801 1783 1805 0.95
10 13 1.6e-05 0.001 19.3 0.5 1 23 1813 1835 1813 1835 0.98
11 13 0.00011 0.0066 16.7 7.6 1 23 1841 1863 1841 1864 0.96
12 13 0.00021 0.013 15.8 5.9 1 23 1869 1891 1869 1891 0.98
13 13 0.029 1.8 9.0 8.2 1 23 1897 1919 1897 1920 0.95

Sequence Information

Coding Sequence
atggtgGACAGTGTGCAGTGCCCCGTGTGCACCTTGTATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCattgctggcaacaacaatggtggTCTGGACAGCGCCCTGGCGGCAGCTGTCATCTCCAGCAGCAGTCGCTGCAGCGTTGCCTCAACCGAAAGCGTCGCCTCAACGCCGCCTGCTGTTGATGTCAAACCGGATGTGGCATCAGTACcatcagcgacagcaacaCAACCACcccaaccaccaccaccaccaccaacagcaacaacaacaacagcaggagcaggagcagtagcatcaacaacaagcacatcGCAATCAACAGCACCGAAGGCTGTCGCATTGCTGgacaacgccagcagcagcagtagcaacaacagcagcagcaacaacaacaacaacaacaaattgagcaaTCCACCGATTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCATAAGCAACGTGTCTGCTGTCTATCCGGCAACCCTGGCAACCGACTATCGCtacgaacagcagcaacagcaacagccacagctacagcagcagcaccagcagctgcatgGCTTTCCACGTGGCACCACCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAACCAACAGCCGCCTGCGCACTTTgcccaccagcaacagcagccgcagtcgaCCATGAAGTTCACgtatgcaacagcagcgttgCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAGCCGACGGCAACGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCATAaccaaaacaagcaacaacaccaacaccaccaaccacagcaacagcaaccacaacacaTAAGCGTACAGCAGcataatgcaaatgcagcaccACCGagtggcaaacaacaacacaatagCAAAATCCATGCGGATATCTTTCTGAatccaccgccaccgccacagCTCACAATTCCATCGTCGGcgtcatcgttgtcgttgtcgctgtccCTGTCGTCATCGACCTCCTCAAGACTGCAACATCCccaacagcaccaccaacaatcCCATGCGGctagcagcagcggcagtagcagtagcaacagcaacagcaactatgcAGCAACCAGCTGCGCTCCCAGCTCCTCGGTTGCTCTGATGTCCGGCACATCGTCGGCACGCGCCAGCAGTCGCCAGTCGAGCAATTCACCCTTTGGTGCCCTGCTGAATGCGGCTGCGCACGCTGCCTGCTCCTCGCCCGCTTCGACTGGGGCGTCTGTGCTCCGCTATGCCGAGTCGCCAGTGGCCCACTATCTGGAGCGGGATAACGGTGATTTCATAGTGCAAGAGACGCCCAAGCACATTGTGGAGTGTGTCGAGAAAGACGACGGTGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTCCACAtacacgacgacgacgaagaggaggaggaggacgaggatGATCAGCAGGGtTGGGCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGCCGAGTTGCACCCAAAACGACAACGAAAAAGTCACGCAAGACAAAATCGAGTGGCAGATTGCACAAGCGCTCCTCCAAGCATCAGCTGGCCACGACGACGGAGGACGAGGACGACTTCATGAGCATCGGCAGCAGTTGTGCCGAAAGCGATCATCATCCagaggagcagctgcagcaacagcagccgcagcaacagcatccgcAGCAATTAGCATCGGCTGGGGGGGCAGCACAGTTGACGGCGAGCTCATCGCCAGCTCAACTTTGCACTGCGCCCTCCACGAGCAgtggagttgctgttgctgctgctgctgccgccgccagtGGTGGTAAATTCATGGCCAGCGGCACAATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGAGTCGCATTGGCGCAGCGCGTCCCTTTGCCGCTGTAGCGCCCATACCGCTCGTCAAGGTGGAAAAGGAGGAACCCATGGATGAATACGATGCAGTTGAGGTCGAGATGCAGTTGGAGCAAAAGCCCAGCCTAGAGCATGCTAGcggcagtagcagtagcagcagcagtagcagcaacagtagcagcagtagcagcagcagcagtggacaTGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGCGGCGAACGTGGCCGCCGAGGATCTCACACAGCCGCTGCCGATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTCTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCacagcgacggcaacggcgacgtcAACGACGAAAAAGACTGAGAACaacgctgctgcagttgctactggcagcaacagtagcaattGCGCCGAATCCCATAGCATATCAGTGAATACGCCCGCCGAGCTTGTGCAGATCAAGAGCGAGAACGTGGAGGCGTCTACATCGAGCAGTGGCAGCATATTGGAAAAGCATCTGACTACCTGCTATGCGGCACAGCAGGCGGCACGCAAGCACTCCGCCGTCAACGATGACGATGCACGTGTCCTGCTCGAGTTTGCCAACTCGAAGCAGCTGCCGATGCCGGGCAACAGCAATCATACCACGTTTGTGGTGAATGCGGCCAGTTTTGCGTCAGCGGGTTCCGTATttgccagcggcagcagcagcagtggtgTCAATGTGCAAAAGACAACCAAGCCGGGCTGCGGCGATGAGTACATTCTGCCCGATGACACCAAGCTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCAcctcgcagcagcaacagcagcatctccaacaacaaacacaacaacagcagcagcagcaacaacaatctttGCAGCAGGCGCAACCATCCGCCTTCACTGAGTTTAGTTTTCTGTACCaccaaaatacaacaacaacaacaacagcagctgcagcagcagcggcggcagcggcaacaacggcGACATCTACTACTTCCAACTTTGCACCGTTTGGcattcagcaacagcaacaacagttgcagttgcaacatcATCCGCAGCATGGGTCTAGCGAGGCAACCAATGCCGCAACGCTTGCATCCTCGTCGAGCAATTCGTCTGCATTGGACCAGGAGTGCTCGATGAATGCCACGTTTCGCGTGGCAAAGCCACAATCAATGCTGGGCGCCTGGTATCAGCCACATCAGGCGCAGCATCAGGTGACATCTTCACACAGTCCACAACATGTGGATCAGCCGAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGATAGCGATATGAGCGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGTGAACAGctgagcaacagcagtagccaTATGCCATCCGCTTCGACATCGACCACCTCGTCATCGTTTGCTGCCGCAGCAACGGAGAGCAGTCTCGTCGGTGGCCTGGGTCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAACAGGAAAGCAACTGCGACATTGAGAACTCTTGGAGTCAATCGatGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACTGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCACGACTATTATCCGGCGCAGGATCTcagtggccagcagcagcagcagcgagagcaAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCACAGCCGGGCGAGCTGGAAGCTTCCTCGAGCTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGCGCTGCGGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCTCAACGGAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACACTGTGTGGCCATCTTCGAGAAGCTAAAGGAGCGCAATGCGCACATGATTGGGGAGCACAACTATGTGCGCCAGAATCGGCGTCTCATCTGCACGCAGGCGCTGGTCAGCGCTGCGATGCTCGCCCAGCCGCTGGCTCAGCAGTCAGAGCAGCAAATGGAgctggagcaacagcaacagcatcagttGCTGCAGGTGAGCCACAGCACGGGTGGCGCCGAGCACGAGGATTCCAAGGATGGTATTGTGAAGATTAAGCAGGAACATTGTCACGACAAGCACGATCCAGCATCGGAGCAATTGCTTGGCCACTTGGAGCTGCCGGATGTGAAGGATGCTGGACTGCTCGAAACCAGTGGTGACAACGGACGCGATGCGGACATGAAGCCACCAACCACTGTTGCTGAGCTTGACGAGAAACCGACCATAGCACCGCTGGCCATGACGACGCCCGCTGCCAAACTGGCTGCTCTTTATCGCATGCTAATTGCATACAACGAATCGAAGCTGGGCCAGGAGCGCAACAATCTAAGCGAACTGGAGCAAAAGGCCATGGAGAAATCTATATTCTTGTGCTACATTTGCCGCACCGATTTTCCCTCTGTGAAGCTGTACGATGCGCATCTAACCGAGCATCCCGCCGAGTGTTTCACTTGCGGAAAGAAATTCTATCGCTGGAAGAACTTCTCGCTGCACCTGAAACGCCATCTGGGCTGGAAGGAGTTTGGGTGCTATGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCTCTCGTCGAGCACATGCGTATGCACACTGGCCAGACGCCACTCAAGTGCAAGATATGCGGCAAGAAGTTCAAGCGATACTCGAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTGTGCCACTGTGGCGAAGTGCTGCCCTCAAAGGCGCGCTTCCTCTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCGAACTCGCTGCGTCGACACATTCGGCTGGCGCATTCGGACAAGTTCGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATTAAGGCGCACATGGCGACGCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGAACGGCCAAACCGTTCAAGTGCGAGTACTGCCCCAAGGCGTTTGTGCGCGAGTTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAACCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGCAACAAGAAGTTCACGTGCGATCAATGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAACATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNNGGLDSALAAAVISSSSRCSVASTESVASTPPAVDVKPDVASVPSATATQPPQPPPPPPTATTTTAGAGAVASTTSTSQSTAPKAVALLDNASSSSSNNSSSNNNNNNKLSNPPIKAVKSAPPTTEAPATTSNNNTPTISNVSAVYPATLATDYRYEQQQQQQPQLQQQHQQLHGFPRGTTTTLVIPQAPPQQHHNFLANQQPPAHFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTATQPHQKPPPAYGAAISQIRSQHNQNKQQHQHHQPQQQQPQHISVQQHNANAAPPSGKQQHNSKIHADIFLNPPPPPQLTIPSSASSLSLSLSLSSSTSSRLQHPQQHHQQSHAASSSGSSSSNSNSNYAATSCAPSSSVALMSGTSSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEDEDDQQGWANSDEEDHVKVPHEHVEDGDDEHEDSRSRVAPKTTTKKSRKTKSSGRLHKRSSKHQLATTTEDEDDFMSIGSSCAESDHHPEEQLQQQQPQQQHPQQLASAGGAAQLTASSSPAQLCTAPSTSSGVAVAAAAAAASGGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPMDEYDAVEVEMQLEQKPSLEHASGSSSSSSSSSNSSSSSSSSSGHGTTSVIRMASTSAANVAAEDLTQPLPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATATSTTKKTENNAAAVATGSNSSNCAESHSISVNTPAELVQIKSENVEASTSSSGSILEKHLTTCYAAQQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGSSSSGVNVQKTTKPGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQHLQQQTQQQQQQQQQSLQQAQPSAFTEFSFLYHQNTTTTTTAAAAAAAAAATTATSTTSNFAPFGIQQQQQQLQLQHHPQHGSSEATNAATLASSSSNSSALDQECSMNATFRVAKPQSMLGAWYQPHQAQHQVTSSHSPQHVDQPSNFIAALSAVDCCSAAVDSDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQREQKRFDFNAVASEYAQPGELEASSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVSAAMLAQPLAQQSEQQMELEQQQQHQLLQVSHSTGGAEHEDSKDGIVKIKQEHCHDKHDPASEQLLGHLELPDVKDAGLLETSGDNGRDADMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
-