Dcog005283.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila cognata
Gene Symbol
-
Assembly
GCA_035041535.1
Location
JAWNLC010000238.1:1297493-1303961[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.054 3.4 8.3 0.2 1 23 1366 1389 1366 1389 0.94
2 13 4.9 3.1e+02 2.1 0.2 1 23 1559 1581 1559 1581 0.91
3 13 0.00019 0.012 16.0 2.7 2 23 1584 1605 1584 1605 0.97
4 13 7.5e-05 0.0048 17.3 0.2 3 23 1613 1633 1611 1633 0.98
5 13 6.2e-07 4e-05 23.8 4.1 2 23 1640 1661 1639 1661 0.97
6 13 5.9 3.8e+02 1.9 0.4 5 23 1674 1692 1672 1692 0.96
7 13 1.5 93 3.8 5.4 3 23 1699 1720 1697 1720 0.93
8 13 0.16 9.9 6.8 0.2 2 23 1731 1751 1730 1751 0.96
9 13 6e-05 0.0038 17.6 0.4 1 19 1757 1775 1757 1779 0.95
10 13 1.7e-05 0.0011 19.3 0.5 1 23 1787 1809 1787 1809 0.98
11 13 0.00011 0.0071 16.7 7.6 1 23 1815 1837 1815 1838 0.96
12 13 0.00022 0.014 15.8 5.9 1 23 1843 1865 1843 1865 0.98
13 13 0.031 2 9.1 8.2 1 23 1871 1893 1871 1894 0.95

Sequence Information

Coding Sequence
atggtgGACAGTGTGCAGTGCCCCGTATGCACCTTGTATCTGCATGCGGGAATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGAAAATGACCATTGCTGGTAACAACAATGGTGGTCTGGACAGCGCCCTGGCGGCAGCTGTCATCtccagcagcagtcgcagcagcgtTGCCTCAACCGAAAGCGTCGCCTCAACGCCGCCTGCTGGTGATGTCAAGCCAGATGTGGCATCAGTaccaacagcgacagcaacacaaCCACCACAGCCGCCACAACTACCCCAACCACCCcaaccaccaccagcaacaacaacagcagcagcatcaacaacaagcacatCGCAATCAACAGCACCCAAAGCTGTCGCATTGCTGGACAacgctagcagcagcagtagcaacatcaacagtagcaacaacaacagcggcagcaacaataataacaaattgagCAATCCACCGATTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCATAAGCAGCGTGGCTGCTGTCTATCCGGCAACCCTGGCAACCGACTATCGCtacgaacagcagcaacagcatcagctgcaTGGCTTTCCACGTGGCACCTCCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAACCAACAGCCGCCTGCGCAATTTGcccatcagcaacagcagccgcagtcgaCCATGAAGTTCACgtatgcaacagcagcgttgCCTCCGCCCCCCTTGCAGCTTTTTGCACAGCAGCCGACGGCAACGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCACCGCCATCAGTCAAATTCGATCTCAGCATAAccaaaacaagcaacaacaccaacaccaacaccaccaacaacaacagcaacaacaacacataaacGTACAGCAgcacaatgcaaatgcaacaccaccaagtggcaagcaacaacacaacagcaaaatccaTGCGGATATCTTTCTGAatccaccgccaccgccacagCTCACAATTCCATCGTCGGCGTCGGTgtcatcgttgtcgttgtcgctgtccCTGTCGTCATCGACCTCCTCAAGACTGCAACATCCccaacagcaccaccaacaatcCCATGCtgctagcagcagcaactatgcAGCCACCAGCTGCGCTCCCAGCTCCTCGGTTGCACTGATGTCCGGGTCACCGTCGGCACGCGCCAGCAGTCGCCAGTCAAGCAATTCGCCCTTTGGTGCCCTGCTGAATGCGGCTGCGCATGCTGCCTGCTCCTCTCCCGCTTCGACTGGGGCGTCTGTGCTACGCTATGCCGAGTCACCAGTGGCCCACTATCTGGAGCGGGAGAACGGTGATTTCATAGTGCAGGAGACGCCCAAGCACATTGTAGAGTGTGTCGAGAAGGACGACGGTGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTCCACAtacacgacgacgacgaagaagaggaagaggaggaggaggacgacgaTGATCAGCAGGGTTGGGCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGTCGAGTTGCATCTAAAACGACAACGAAAAAGtcacgcaaaacaaaaacgagtGGCAGATTGCACAAGCACGCCTCCAAGCATCAGCTGGCCACGACGACGGAGGACGAGGACGACTTCATGAGCATAGGCAGCAGTTGTGCCGAAAGCGAGCATCATccagaggagcagcagcaccaacagcagccgcagcaggtACCGCCGGTTGGGGGGACAGCGCAATTGGCGGCGAGCTCATCGCCAGCTCAACTTTGCACTGCGCCCTCCACGAGcagtggtgctgctgttgctgctgctgccgccgtcAGTAGTGGCAAATTCATGGCAAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGACTCGCATTGGCGCAGCGCGTCCCTTTGCCGCTGTGGCGCCCATACCGCTTGTCAAGGTTGAAAAGGAGGAACCCATGGACGAATATGATGCCGTTGAAGTCGAGATGCAGTTGGAGCAGAAGCCTAGCCTGGAGCatgccagcggcagcagtagtagcagcagcagtagcagtaacagtagcagcagcagcagcagtggacATGGCACCACCAGCGTGATACGCATGGCTAGCACCAGTGGCGCGAACGTTGCCGCCGAGGATCTCACACAGCCGCCGCCCATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTTTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCcacagcgacggcgacgtcaATGACGAAAAAGACTGAGaacaacgctgctgctgttgctactggcagcaacagtagcaattGCACCGAATCCCACAGCATATCAGTGAATACGCCCGCCGAGCTAGTGCAGATCAAGAGCGAGAACGTGGAGGCGTCCACATCCAGTAGTGGCAGCATATTGGAAAAGCATCTGACTACCAGTTATACGGCACATCAGGCGGCACGCAAGCACTCCGCCGTCAATGATGACGATGCACGTGTCCTGCTCGAGTTTGCCAACTCGAAGCAGCTGCCGATGCCGGGAAATAGCAATCATACCACGTTTGTGGTGAACGCGGCCAGTTTTGCGTCAGCGGGTTCCGTAtttgccagcggcagcagcggtgTCAATGTGCAAAAGTCAACCAAGCCGGGTTGTGGCGATGAGTACATTCTACCCGATGACACCAAACTGGAGGTGGATGAAATTGTGATATCCTCATCGTCTTCCTATGCCTCCACctcgcagcaacagcagcagcatctgcaacaacaaacacaacatcagcagcaacaacaatcttTGCAGCAGGCTCAACCATCCGCCTTCACTGAATTTAGTTTTCTGTACcaccaaaacacaacaacaacaacagcagcagcagcaacaacggcggCGACACCTACTACTTCCAACTTTGCACCGTTTGgcattcagcagcagcaacagcaacaacagttgcagttgcaacatcATCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCCACGCTTGCGTCCTCGTCGAGCAATGCGTCTGCATTGGACCAGGAGTGCTCGATGAATGCCACGTTTCGCGTGTCAAAGCCACAATCAATGCTGGGCGCCTGGTATCAGCCACATCAGGCACAGCATCAGGTGACATCTTCGCACAGTCCACAACATGTGGATCAACCTAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGATAGCGATATGAGTGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACAgctgagcaacagcagcagccatatGCCCTCCGCCTCGACATCGACCACATCGTCATCGTTTGCTGCCGCAGCAACGGAGAGCAGTCTCGTCGGTGGCCTGGGTCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAGCAGGAAAGCAACTGCGACATTGAGAACTCTTGGAGTCAATCGATGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAACCAGCAGCTGGCCGATTGGCGTCACGACTACTATCCGGCGCAAGATCTCagtggccagcagcagcagcagcgagagcAAAAACGATTTGACTTCAATGCGGTCGCTTCGGAGTACGCACAGCCGAGCGAGCTGGAAGCTTCCTCGAGCTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACTTCCCGTGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCGCAACGGAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACACTGTGTGGCCATCTTCGAGAAGCTAAAGGAGCGCAATGCGCATATGATTGGCGAGCACAACTATGTTCGCCAGAATCGCCGTCTCATCTGCACACAAGCGCTGGTCAACGCTGCGATGCTGGCCCAGCCGATGGGTCAGCAGCCAGAACAGCAGatggagctgcagcagcagcaacagcatcagttGCTGCAGGTGGGCCACAGCACGGGCGGCGCCGAGCACGAGGATTCCAAGGATGGTATTGTGAAGATTAAGCAAGAGCACTGTCAGGACAAGCACGATCCGGCATCGGAACAATTGCTTGGCCACTTGGAGATGCCGGATGTGAAGGACGCTGGCCTGCTCGATGCCAGTGGGGAAAGCGGACGCGATGCGGACATGAAGCCACCAACCACTGTTGCTGAGATGGACGAAAAACCGACCATAGCACCGCTGGCCATGACGACGCCCGCTGCCAAACTAGCTGCTCTTTATCGCATGCTGATTGCCTACAACGAATCGAAGCTGGGCCAGGAGCGCAACAATCTGAGCGAACTGGAGCAAAAGGCCATGGAGAAATCTATTTTCTTGTGCTACATTTGCCGCACCGATTTCCCCTCTGTGAAGCTGTACGATGCGCATCTAACAGAGCATCCCGCCGAGTGTTTCACCTGCGGCAAGAAATTCTATCGTTGGAAGAACTTCTCGCTGCACCTGAAACGTCATCTGGGTTGGAAGGAGTTCGGCTGCTATGTCTGCGACAAGAAGTTTGTGGTGCGCAGTGCTCTCGTCGAACACATGCGGATGCACACTGGCCAGACGCCACTGAAGTGCAAGATATGCGGCAAGAAGTTCAAGCGATATTCGAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTGTGCCACTGTGGCGAAGTGCTGCCCTCAAAGGCGCGCTTTCTGTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGATTCGTTCATGCCAACTCGCTGCGTCGACACATTCGGCTGGCGCATTCGGACAAGTTCGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAACAGATCTTTGCGAAGACATCGATTAAGGCGCACATGGCGACGCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGCACGGCCAAACCGTTCAAGTGCGAATACTGCCCCAAGGCGTTCGTGCGCGAATTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGCAACAAGAAGTTCACGTGCGATCAGTGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAGCATCTGAAGATACATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVKMTIAGNNNGGLDSALAAAVISSSSRSSVASTESVASTPPAGDVKPDVASVPTATATQPPQPPQLPQPPQPPPATTTAAASTTSTSQSTAPKAVALLDNASSSSSNINSSNNNSGSNNNNKLSNPPIKAVKSAPPTTEAPATTSNNNTPTISSVAAVYPATLATDYRYEQQQQHQLHGFPRGTSTTLVIPQAPPQQHHNFLANQQPPAQFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTATQPHQKPPPAYGTAISQIRSQHNQNKQQHQHQHHQQQQQQQHINVQQHNANATPPSGKQQHNSKIHADIFLNPPPPPQLTIPSSASVSSLSLSLSLSSSTSSRLQHPQQHHQQSHAASSSNYAATSCAPSSSVALMSGSPSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEEEEDDDDQQGWANSDEEDHVKVPHEHVEDGDDEHEDSRSRVASKTTTKKSRKTKTSGRLHKHASKHQLATTTEDEDDFMSIGSSCAESEHHPEEQQHQQQPQQVPPVGGTAQLAASSSPAQLCTAPSTSSGAAVAAAAAVSSGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASTRIGAARPFAAVAPIPLVKVEKEEPMDEYDAVEVEMQLEQKPSLEHASGSSSSSSSSSNSSSSSSSGHGTTSVIRMASTSGANVAAEDLTQPPPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATSMTKKTENNAAAVATGSNSSNCTESHSISVNTPAELVQIKSENVEASTSSSGSILEKHLTTSYTAHQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGSSGVNVQKSTKPGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQHLQQQTQHQQQQQSLQQAQPSAFTEFSFLYHQNTTTTTAAAATTAATPTTSNFAPFGIQQQQQQQQLQLQHHPQHGSSEATNAATLASSSSNASALDQECSMNATFRVSKPQSMLGAWYQPHQAQHQVTSSHSPQHVDQPSNFIAALSAVDCCSAAVDSDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQREQKRFDFNAVASEYAQPSELEASSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVNAAMLAQPMGQQPEQQMELQQQQQHQLLQVGHSTGGAEHEDSKDGIVKIKQEHCQDKHDPASEQLLGHLEMPDVKDAGLLDASGESGRDADMKPPTTVAEMDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
-