Dhaw005711.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila hawaiiensis
Gene Symbol
-
Assembly
GCA_037043685.1
Location
JBAMBA010000121.1:1482831-1489298[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.05 3.3 8.3 0.2 1 23 1389 1412 1389 1412 0.94
2 13 4.5 3e+02 2.1 0.2 1 23 1582 1604 1582 1604 0.91
3 13 0.00018 0.012 16.0 2.7 2 23 1607 1628 1607 1628 0.97
4 13 7e-05 0.0046 17.3 0.2 3 23 1636 1656 1634 1656 0.98
5 13 5.8e-07 3.9e-05 23.8 4.1 2 23 1663 1684 1662 1684 0.97
6 13 5.5 3.7e+02 1.9 0.4 5 23 1697 1715 1695 1715 0.96
7 13 1.4 91 3.8 5.4 3 23 1722 1743 1720 1743 0.93
8 13 0.15 9.7 6.8 0.2 2 23 1754 1774 1753 1774 0.96
9 13 5.6e-05 0.0037 17.6 0.4 1 19 1780 1798 1780 1802 0.95
10 13 1.6e-05 0.0011 19.3 0.5 1 23 1810 1832 1810 1832 0.98
11 13 0.0001 0.0069 16.7 7.6 1 23 1838 1860 1838 1861 0.96
12 13 0.0002 0.013 15.8 5.9 1 23 1866 1888 1866 1888 0.98
13 13 0.029 1.9 9.0 8.2 1 23 1894 1916 1894 1917 0.95

Sequence Information

Coding Sequence
atggtGGACAGTGTGCAGTGCCCCGTGTGCACTTTGTACCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCattgctggcaacaacaatggtggTCTGGACAGCGCCCTGGCGGCAGCTGTCATCTCCAGCAGCAGTCGCTGCAGCGTTGCCTCAACCGAAAGCGTCGCCTTAACGCCGCCTGCTGTTGGTGTCAAACCGGATGTGGCATCAGTACCAACAGGGACAACAACACAACCGCCACAGCCACCACAACCACCCcaaccgccaccaccaccagcagcaacaacaacaacagcgcgaGCAgtagcatcaacaacaagcacatcGCAATCAACAGCACCCAAGGCTGTCGCATTGCTGgacaacgccagcagcagcagtagcaacaacagcagcagcagcaacaacaacaacaacaacaacagcaacaacaaattgagcaaTCCACCGACTAAGGCAGTTAAGAGTGCGCCACCCACGACTGAGGCGCCAGCCACCacatccaacaacaacacacccACCATAAGCAACGTGTCAGCTGTCTATCCGGCAACCCTGGCAACCGACTATCGCtacgaacagcagcaacagccacagctacagcagcagctgcatggCTTTCCACGTGGCACCACCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAACCAACAGCCGCCTGCACAGTTTgcccaccagcaacagcagccgcagtcgaCCATGAAGTTCACgtatgcaacagcagcgttgCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAGCCGACGGCAACGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCATAaccaaaacaagcaacaacaccaacaccacccacaacagcaaccacaacacaTAAGCGTACAGCAGcataatgcaaatgcagcaccACCGagtggcaaacaacaacacaatggCAAAATCCATGCGGATATCTTTCTGAatccaccgccaccgccacagCTCACAATTCCATCGTCGgcgtcatcgttgtcgttgtcgctgtccCTGTCGTCATCGACCTCCTCAAGACTGCAACATCCCcaacagcaccaccaacaatCCCATGcggctagcagcagcagcagtagcagtagcaacagcaactatgcAGCAACCAGCTGTGCTCCCAGCTCCTCGGTTGCTCTGATGTCCGGCACATCGTCGGCACGCGCCAGCAGTCGCCAGTCGAGCAATTCACCCTTTGGTGCCCTGCTGAATGCGGCTGCGCACGCTGCCTGCTCCTCGCCCGCTTCGACTGGGGCGTCTGTGCTGCGCTATGCCGAGTCGCCAGTGGCCCACTATCTGGAGCGGGATAACGGTGATTTCATAGTGCAGGAGACGCCCAAGCACATTGTGGAGTGTGTCGAGAAAGACGACGGTGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTCCACAtacacgacgacgacgaagaagaggaggaggacgaggatGATCAGCAGGGtTGGGCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGCCGAATTGCACCCAAAATGACAACGAAAAAGTCACGCAAGACAAAATCGAGTGGCAGATTGCACAAGCGCGCCTCCAAGCATCAGCTGGCCACGACGACGGAGGACGAGGACGACTTCATGAGCATAGGCAGCAGTTGTGCCGAAAGCGATCATCATCCagaggagcagctgcagcaacagcagccgcagcaacagcatccgcAGCAATTAGCATCGGCTGGGGTGGCAGCACAATTGGCGGCGAGCTCATCGCCGGCACAACTTTGCACTGCGCCCTCCACGAGCAgtggagctgctgttgctgctgctgctgccgccgccagtGGTGGTAAATTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGACTCGCATTGGCGCAGCGCGTCCCTTTGCCGCTGTAGCGCCCATACCGCTCGTCAAAGTGGAAAAGGAGGAACCCATGGATGAATATGATGCCGTTGAGGTCGAGATGCAGTTGGAGCAAAAGCCCAGCCTAGAGCATGctagcggcagcagcagtagcagcagcagtagcagcaacagtagcagcagcaacagtagcagcagcagcagtggacaTGGCACAACCAGCGTGATACGCATGGCTAGCACCAGTGTGGCGAACGTTGCCGCCGAGGATCTCACACAGCCGCCGCCGATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTCTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGTCacagcgacggcaacggcgacgtcAACGACGAAAAAGACTGAGaacaacgctgctgctgttgctactggcAGCAATAGTAGCAATTGCGCCGAATCCCATAGCATATCAGTGAATACGCCCGCCGAGCTTGTGCAGATCAAGAGCGAGAACGTGGAGGCGTCCACATCGAGCAGTGGCAGCATATTGGAAAAACATCTGACTACCAGCTATGCGGCACAGCAGGCGGCACGCAAGCACTCCGCCGtcaacgatgacgatgccCGTGTCCTGCTCGAGTTTGCCAACTcgaagcagctgctgatgccgGGCAACAGCAATCATACCACGTTTGTGGTGAACGCTGCCAGTTTTGCGTCAGCGGGTTCCGTATttgccagcggcagcagcagcagcggtgtcAATGTGCAAAAGTCAACCAAGCCGGGCTGTGGCGATGAGTACATTCTGCCCGATGACACCAAGCTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCAcctcgcagcagcaacagcagcaactccaacaacaaacacaacagcagcagcaacaacaatctttGCAGCAGGCGCAACCATCCGCCTTCACTGAGTTTAGTTTTCTGTACcaccaaaacacaacaacaacagcagctgcagcagtagcggcagcggcaacaacggcGACATCAACTACTTCCAACTTTGCACCGTTTGGcattcagcaacagcaacaacagttgcagttgcaacatcATCCGCAGCATGGGTCCAGCGAGGCAACCAATGCCGCAACGCTTGCATCCTCGTCGAGCAATTCGTCTGCATTGGACCAGGAGTGCTCGATGAATGCCACGTTTCGCGTGGCAAAGCCACAATCAATGCTGGGCGCCTGGTATCAGCCACATCAGGCGCAGCATCAGGTGACATCTTCGCATAGTCCACAAAATGTGGATCAGCCGAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGATAGCGATATGAGCGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACAgctgagcaacagcagcagccatatgCCATCCGCTTCGACATCGACCACATCGTCATCGTTTGCTGCCGCAGCAACGGAGAGCAGTCTCGTCGGTGGCCTGGGCCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGTGAGATTTCCGAACAGGAAAGCAACTGCGACATTGAGAACTCTTGGAGTCAATCGatgTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCACGACTATTATCCGGCGCAGGATCTCagtggccagcagcagcagcagcagcgagagcAAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCACAGCCGGGCGAGCTGGAAGCTTCCTCGAGTTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGCGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCGCTGGCTCAACGGAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACACTGTGTGGCCATCTTCGAGAAGCTAAAGGAGCGCAATGCGCACATGATTGGTGAGCACAACTATGTGCGCCAAAATCGGCGTCTCATCTGCACGCAGGCGCTGGTCAGCGCTGCGATGCTCGCCCAGCCGCTGGCTCAGCAGTCAGATCAGCAaatggagctggagcagcagcaacagcatcagttGCTGCAGGTGAGCCACAGCACGGGCGGCGCCGAGCACGAGGATTCCAAGGATGGTATTGTGAAGATTAAGCAGGAACATTGTCACGATAAGCATGATCCAGCATCGGAGCAATTGCTTGGCCACTTGGAGCTGCCGGATGTGAAGGATGCTGGCCTGCTCGAAACCAGTGGTGACAACGGACGCGATGCGGACATGAAGCCACCAACCACTGTTGCTGAGCTTGACGAGAAACCGACCATAGCACCGCTGGCCATGACGACGCCCGCTGCCAAACTGGCTGCTCTTTATCGCATGCTAATTGCCTACAACGAATCGAAGCTGGGTCAGGAGCGCAACAATCTGAGCGAACTGGAGCAAAAGGCCATGGAGAAATCTATATTCTTGTGCTACATTTGTCGCACCGATTTCCCCTCTGTGAAGCTGTACGATGCGCATCTAACCGAGCATCCCGCCGAGTGTTTCACTTGCGGCAAGAAATTCTATCGCTGGAAGAACTTCTCGCTGCACCTGAAACGCCATCTGGGCTGGAAGGAGTTTGGCTGCTATGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCTCTCGTCGAGCACATGCGGATGCACACTGGCCAGACGCCACTCAAGTGCAAGATATGCGGCAAGAAGTTCAAGCGATACTCGAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTGTGCCACTGTGGCGAAGTGCTACCCTCAAAGGCCCGCTTCCTGTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCGAACTCGCTGCGTCGACACATCCGGCTGGCGCATTCGGACAAATTCGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATTAAGGCGCACATGGCGACGCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGAACGGCCAAACCGTTCAAGTGCGAGTACTGCCCGAAGGCGTTTGTGCGCGAGTTGGATTTCAAGAATCATATGAATGCACACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGCAACAAGAAGTTCACGTGCGATCAATGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAACATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNNGGLDSALAAAVISSSSRCSVASTESVALTPPAVGVKPDVASVPTGTTTQPPQPPQPPQPPPPPAATTTTARAVASTTSTSQSTAPKAVALLDNASSSSSNNSSSSNNNNNNNSNNKLSNPPTKAVKSAPPTTEAPATTSNNNTPTISNVSAVYPATLATDYRYEQQQQPQLQQQLHGFPRGTTTTLVIPQAPPQQHHNFLANQQPPAQFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTATQPHQKPPPAYGAAISQIRSQHNQNKQQHQHHPQQQPQHISVQQHNANAAPPSGKQQHNGKIHADIFLNPPPPPQLTIPSSASSLSLSLSLSSSTSSRLQHPQQHHQQSHAASSSSSSSSNSNYAATSCAPSSSVALMSGTSSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEDEDDQQGWANSDEEDHVKVPHEHVEDGDDEHEDSRSRIAPKMTTKKSRKTKSSGRLHKRASKHQLATTTEDEDDFMSIGSSCAESDHHPEEQLQQQQPQQQHPQQLASAGVAAQLAASSSPAQLCTAPSTSSGAAVAAAAAAASGGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASTRIGAARPFAAVAPIPLVKVEKEEPMDEYDAVEVEMQLEQKPSLEHASGSSSSSSSSSNSSSSNSSSSSSGHGTTSVIRMASTSVANVAAEDLTQPPPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKVTATATATSTTKKTENNAAAVATGSNSSNCAESHSISVNTPAELVQIKSENVEASTSSSGSILEKHLTTSYAAQQAARKHSAVNDDDARVLLEFANSKQLLMPGNSNHTTFVVNAASFASAGSVFASGSSSSGVNVQKSTKPGCGDEYILPDDTKLEVDEIVISSSSSYASTSQQQQQQLQQQTQQQQQQQSLQQAQPSAFTEFSFLYHQNTTTTAAAAVAAAATTATSTTSNFAPFGIQQQQQQLQLQHHPQHGSSEATNAATLASSSSNSSALDQECSMNATFRVAKPQSMLGAWYQPHQAQHQVTSSHSPQNVDQPSNFIAALSAVDCCSAAVDSDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQQQREQKRFDFNAVASEYAQPGELEASSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVSAAMLAQPLAQQSDQQMELEQQQQHQLLQVSHSTGGAEHEDSKDGIVKIKQEHCHDKHDPASEQLLGHLELPDVKDAGLLETSGDNGRDADMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00583141;
90% Identity
iTF_00564835;
80% Identity
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