Datr007976.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila atripex
Gene Symbol
-
Assembly
GCA_035045925.1
Location
JAWNOP010000052.1:6993321-6999947[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00021 0.016 15.6 3.4 1 23 279 301 279 301 0.98
2 11 0.0011 0.084 13.4 10.4 1 23 308 330 308 330 0.96
3 11 0.0001 0.008 16.6 6.5 1 23 336 358 336 358 0.98
4 11 0.00047 0.036 14.5 1.6 1 23 364 386 364 386 0.95
5 11 2.2e-05 0.0017 18.7 0.5 1 23 392 414 392 414 0.97
6 11 2.2e-05 0.0017 18.7 0.1 1 23 420 442 420 442 0.98
7 11 0.00013 0.0098 16.3 2.0 1 23 447 470 447 470 0.97
8 11 0.01 0.79 10.3 0.6 1 23 476 499 476 499 0.96
9 11 0.00017 0.013 15.9 0.1 1 23 561 583 561 583 0.98
10 11 0.015 1.2 9.8 2.7 1 23 699 721 699 721 0.95
11 11 0.0045 0.35 11.4 4.9 5 23 734 752 726 752 0.92

Sequence Information

Coding Sequence
atgtgcGCCGCCCAGAATCCGCCGCCCTTTGGCTATACCTGGGGCTTCGCAGACAACGGCAGCCGCACCGCCGAATCGGTACTGGAGATATCGCCGAACATCAACTACACGGTCAGCGGAGAGTCGATGCCCTATTTGTTAGCCACAGATGGATCACTGGCCGTTCAAAAGGATGTGAAAGGTGCCCTTGCAGCAGCCGGCAACAAAAATGTCGTCCGTCGTATGTTCGTTGTAAACGATCCCTCATTTCCGCCTGGAACTCAAAGAGTTATAACCACAGGAGGCGCCTCTACGGTGGTCAAGAAGCAGGACGCCAACCAGCAGGTCCTCAGCCTCGACAAGAACTATCTTCTGGTGGATCAGGccacggcagcagcagctgcagccgcGGCGGCTGGGGATCCGTCGGCCCATCACCAGTTAACCAACGGCAGCATCGTCGATGCCAAGACTGGGCAGACAGTACTGACCGCCGGATCGGCGGCCAAGTCGCACTTCGGCTCGATCGGAGCCCTGCATCTCACGCAGGAGGAGTGCAACGAGATCCTGATCAAGCGCGCTATCGCCGCTGGCCACCATCAGACGCACACGATCACAACTGCCGACGGAGCGCATCATCATGCCGCGTCTGGCGGGACACCAAGTGACATAATTCCTGGTATTTCAGTTCAAGTACAGAAAGTGATCCAGGGACTCGAGGAGAACGAGGACTCGCAGGGCGACGCACCCAACTTGAAGTTGGAGCCAGGCACATTAGAGTTGTCCCCCAAGACCGAAATACAGGAATCAATGCATTTCAGCGAaACGGACGCCACTATTAAGAAGGAACGCCCGTACAGTTGCGACGAGTGCGGCAAGTCCTTTCTGCTCAAGCATCACTTGACGACCCACGCACGCGTACACACAGGTGGTGAACGCCCCCATATCTGCAGCCATTGCGGCAAGAGCTTCGCGCACAAGCACTGCCTTAACACACATCTGTTGCTGCACTCGACGGAGCGGCCGTATCAGTGCCAGGAGTGCAAGAAGAGCTTCACCCTCAAGCACCACCTGCTGACTCACTCGCGCGTTCACAGCCGCGAGCGCCCATTCGTCTGCCAGGAGTGCGGACGTGCCTTTCCCCTGAAGCGTCACCTGGTAACGCACAGCAAGTTCCACGCCGGCGAACGACCGTACGTGTGCGAGGAATGCGGTGAGAGCTTTGCCCAGGAGAACCACCTGATTATGCACTCGCGCTTTCATGGTTCCTTGAATCCATTCGTTTGCGCCGAGTGCGGAGCCTCGTTTCCACGCAAGTTCCAGCTGGTTAATCACGGACGCATCCACGGCAAGATACCCCACTCCTGCACAGTGTGCGGCAAGGAGTTTCTACAAAAGCGAACGCTAGTTTCCCACATGAGGCGTGTACACACTGGCGAGCAGGCTCATCCCTGCGTCAGCTGCGGCGAGGGCTTCCTCACCAAGGCCGAACTGCACCAGCACGTAAGGACGGCGCACAACGGCGTAAATCCCAATACGAGCAGTGCCACCATTATCGCCAATCAACAGCAGCTGCAACAGCCCCACCACCATCCTGGCCAGCAGACGCATCCGCAGACCATAACAGTGGTCAGCAATCCGGCCAATTCCACGCTCCTGACGGTCTCCACCACGGACGCCAATGGCGTGGCACGTCCGCAGTTTGTTTGCCGcgaATGTGGCAGCGCCTTTAACAGCCGGGAAGCGTTGGCCCTGCACTTGCGCCTTCACACCGGCGATAAGAGTCTGATGACCGATTTGTGCGCCCTGACAGCCGCGCTGCCTGGCCACTTTTTGAGCACGGCCAGCCTGAATCCCGGCACAGTGGTCACCGCCAATCCGAACCTGGTGGGCCAGAGCCCAGTGCCCGTACAGATAATATCATCCACCGGGCAGGTGATGTCGCAGACCACCCTGGTGCAGGCCGCCAACTCGACCCATCCGCAAGCGGTGGTCACCGCAGTGCCCACTATGCCGGTGCacggccagcagcagcatctgcatgtgcagcagcagcaacaacagcaacagcagcagcatgtgGTGTCGGTGGCGCCGGCCAACAAACCGAAGTCGCACTTCTGCGCCAGCTGCGGCAAAGGATTCGCCGCCAAGCACGGACTCATGCAGCACAATCGCCGGCATCCGAACGGCGGCTGCACCGTCCGCACCCATGTGTGCGAGTGCGGCAAGGCCTTCTTCCAGAAGAACCACCTGATGCTGCATCAGCGCCAGCACTTGGAGACGAAGCCAGCCATATCGCAGCAACAGGAACAGCAGGCGGATGCCAGCGGCGGCCAGCAGCCGGTTCAGGTACAGATCTTGTCCGACGGCCAGATACACGGCAAGGTCATCAAGTACGAGGTCTGCCGCAACGCCCTACCGGAGGACCAGCAGCAGGCGGAGTAA
Protein Sequence
MCAAQNPPPFGYTWGFADNGSRTAESVLEISPNINYTVSGESMPYLLATDGSLAVQKDVKGALAAAGNKNVVRRMFVVNDPSFPPGTQRVITTGGASTVVKKQDANQQVLSLDKNYLLVDQATAAAAAAAAAGDPSAHHQLTNGSIVDAKTGQTVLTAGSAAKSHFGSIGALHLTQEECNEILIKRAIAAGHHQTHTITTADGAHHHAASGGTPSDIIPGISVQVQKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTEIQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICSHCGKSFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRTAHNGVNPNTSSATIIANQQQLQQPHHHPGQQTHPQTITVVSNPANSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHGQQQHLHVQQQQQQQQQQHVVSVAPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEQQADASGGQQPVQVQILSDGQIHGKVIKYEVCRNALPEDQQQAE