Dath009574.1
Basic Information
- Insect
- Drosophila athabasca
- Gene Symbol
- -
- Assembly
- GCA_008121215.1
- Location
- VMQQ01000022.1:1522359-1531376[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0002 0.014 15.6 3.4 1 23 283 305 283 305 0.98 2 11 0.001 0.071 13.4 10.4 1 23 311 333 311 333 0.96 3 11 9.9e-05 0.0067 16.6 6.5 1 23 339 361 339 361 0.98 4 11 0.00045 0.031 14.5 1.6 1 23 367 389 367 389 0.95 5 11 2.2e-05 0.0015 18.7 0.5 1 23 395 417 395 417 0.97 6 11 2.1e-05 0.0014 18.7 0.1 1 23 423 445 423 445 0.98 7 11 0.00012 0.0083 16.3 2.0 1 23 450 473 450 473 0.97 8 11 0.051 3.4 8.0 0.3 1 23 479 502 479 502 0.94 9 11 0.00016 0.011 15.9 0.1 1 23 562 584 562 584 0.98 10 11 0.015 1 9.7 2.7 1 23 700 722 700 722 0.95 11 11 0.0043 0.29 11.4 4.9 5 23 735 753 727 753 0.92
Sequence Information
- Coding Sequence
- ATGTGCGCCGCCCAGAACCCACAGCCGCCCTTCGGCTACACCTGGGGCTTCGCAGACAACGGCAGCCGCACCGCCGAATCAGTTCTGGAAATATCGCCCAACATAAATTACACCGTCAGTGGGGAATCGATGCCCTATCTGCTGTCCACGGATGGATCATTGGCCGTACAAAAGGATGTCAAAGGTGCTCTCACCGGCAATAAGGGGAATGTTGTGCGTCGCATGTACGTTGTGAACGATCCTTCGTTTCCGCCTGGTACACAGAGAGTAATTACCACTGGGGGAGGCTCGTCGGTAGTCAAGAAACAGGATTCGCAGCAGCAGGTGCTGAGCCTGGACAAGAACTATCTCCTGGTCGATCAGGCAACTgccgcagcagctgcagccgcgGCTGCCGGGGATCCCTCGGTTGGCCACCACCACACATTGACCAACGGTAGTATTGTCGATGCCAAGACCGGACAGACGGTGCTGACGGCGGGCTCCGCGGCGGCCAAGTCGCACTTTGGGTCAATTGGGGCGCTGCACCTCACCCAAGAAGAGTGCAACGAGATCCTGATTAAGCGCGCCATCGCTGCCGGCCACCATCAGACGCACACAATCACCGCTGCCGACGGATCGCATCATCATAGCTCGGCGTCTGGCGCGACACCAAGTGACATACTTCCTGGTATTTCAGTTCAAGTTCAGAAAGTAATACAAGGACTCGAAGAGAACGAGGACTCGCAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAGTTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACGGACGCCACCATCAAGAAGGAACGCCCGTACAGTTGCGACGAGTGCGGCAAGTCCTTTCTGCTCAAGCATCATTTGACAACTCACGCACGCGTGCACACAGGTGAGCGACCCCATATCTGTTCCCATTGCGGCAAAAGCTTCGCGCACAAACACTGTCTGAACACGCATCTACTGCTGCATTCAACCGACCGACCCTACCAGTGCCAGGAGTGCAAGAAGAGCTTCACCCTCAAGCATCATCTGCTAACGCACTCGCGCGTTCATAGCCGCGAGCGACCCTTCGTGTGCCAGGAGTGTGGACGTGCCTTCCCGCTCAAGCGGCACCTGGTCACGCACAGCAAATTCCACGCCGGCGAACGTCCATACGTCTGCGAGGAATGCGGTGAGAGCTTTGCCCAGGAAAACCATCTTATTATGCACTCGCGCTTCCATGGTTCATTGAATCCATTTGTTTGCGCTGAGTGCGGTGCCTCGTTTCCACGCAAGTTCCAGTTGGTGAATCACGGACGCATACACGGCAAGATCCCCCACTCCTGTACCGTTTGCGGCAAAGAGTTTTTACAGAAGCGAACGCTAGTTTCCCACATGAGACGTGTACACACCGGCGAGCAGGCGCATCCGTGCGTTAGCTGTGGCGAGGGCTTCCTGACCAAGGCTGAGCTGCACCAGCACGTGCGGGCAGCGCACAATGGCGTCAATCCTAACACGAGCAGTGCCACCATCATAGCCAACCAGCAGcagctgcaacagcctCACCACCATCCGGGACAGCATCCGCAGACGATCACCGTCGTGAGTAACCCAGGCAACTCTACGCTTCTCACGGTCTCTACCACGGATGCCAATGGTGTGGCTCGTCCGCAGTTCGTTTGCCGCGAGTGCGGTAGCGCCTTCAACAGCCGCGAGGCCTTGGCCCTGCATTTGCGCCTGCACACCGGCGATAAGAGTCTGATGACAGATTTGTGCGCCTTGACAGCAGCGCTGCCGGGGCACTTCTTGAGCACGGCCAGCCTGAACCCGGGCACTGTGGTAACGGCCAACCCGAATTTGGTGGGCCAAAACCCAGTGCCCGTGCAGATCATATCGTCCACCGGCCAGGTAATGTCGCAGACTACGCTGGTGCAGGCCGCCAACTCGACCCATCCGCAGGCCGTCGTTACTGCCGTGCCAACGATGCCCgtgcatcagcagcagcacatgcAGCATGTtgcccagcaacaacaacagcagcagcaacacaacGTGGTAAATGTGGTGCCGGCCAACAAGCCCAAGTCGCATTTCTGCGCCAGCTGTGGCAAGGGATTCGCCGCCAAGCACGGTCTCATGCAGCACAACCGCCGCCACCCGAATGGCGGTTGCACGGTGCGCACTCACGTCTGCGAGTGCGGAAAGGCCTTCTTCCAGAAGAACCATCTGATGCTGCACCAGCGCCAACATTTGGAGACGAAGCCAGCCATATCGCAGCAACAGgaacagcagcagcagcaacaacaggagGCGGCCGTGGGAGCGTCGCCGGCTGGACAGCAACCGGTGCAGGTGCAGATCCTGCCCGATGGCCATATACACGGCAAGGTCATCAAGTACGAGATCTGTCGCAGTGTGCTGCCAGAGGATCAGGCCAcaacacagcaacagcagcagtcagGCATGGATGTGGAGTAG
- Protein Sequence
- MCAAQNPQPPFGYTWGFADNGSRTAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGALTGNKGNVVRRMYVVNDPSFPPGTQRVITTGGGSSVVKKQDSQQQVLSLDKNYLLVDQATAAAAAAAAAGDPSVGHHHTLTNGSIVDAKTGQTVLTAGSAAAKSHFGSIGALHLTQEECNEILIKRAIAAGHHQTHTITAADGSHHHSSASGATPSDILPGISVQVQKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGERPHICSHCGKSFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRAAHNGVNPNTSSATIIANQQQLQQPHHHPGQHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQNPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHQQQHMQHVAQQQQQQQQHNVVNVVPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEQQQQQQQEAAVGASPAGQQPVQVQILPDGHIHGKVIKYEICRSVLPEDQATTQQQQQSGMDVE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00481685;
- 90% Identity
- iTF_00603515;
- 80% Identity
- -