Dmim013936.3
Basic Information
- Insect
- Drosophila mimetica
- Gene Symbol
- -
- Assembly
- GCA_037075245.1
- Location
- JBAMCH010000014.1:29736187-29742985[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00024 0.018 15.6 3.4 1 23 280 302 280 302 0.98 2 11 0.0012 0.09 13.4 10.5 1 23 309 331 309 331 0.96 3 11 0.00012 0.009 16.6 6.5 1 23 337 359 337 359 0.98 4 11 0.00053 0.041 14.5 1.6 1 23 365 387 365 387 0.95 5 11 2.5e-05 0.002 18.7 0.5 1 23 393 415 393 415 0.97 6 11 2.5e-05 0.0019 18.7 0.1 1 23 421 443 421 443 0.98 7 11 0.00014 0.011 16.3 2.0 1 23 448 471 448 471 0.97 8 11 0.012 0.89 10.3 0.6 1 23 477 500 477 500 0.96 9 11 0.00019 0.015 15.9 0.1 1 23 563 585 563 585 0.98 10 11 0.017 1.3 9.7 2.7 1 23 708 730 708 730 0.95 11 11 0.0051 0.39 11.4 4.9 5 23 743 761 735 761 0.92
Sequence Information
- Coding Sequence
- ATGTGCGCCGCCCAGAATCCGCCGCCCTTCGGCTATACCTGGGGCTTTGCTGACAACGGCAGCCGCGCCGCCGAATCGGTACTGGAGATATCGCCCAACATCAACTACACGGTCAGCGGGGAGTCGATGCCCTATCTGTTATCGACGGATGGATCATTGGCTGTTCAAAAGGAAGTTAAAGGCCTCACAGCTGGCGGCAAAAATAATGTCGTTCGCCGCATGTTCGTCGTAAACGATCCATCATTTCCGCCTGGAACTCAGAGAGTAATCACAGCCGGTGGAGCATCGACGGTGGTCAAGAAGCAGGACCCCAATCAGCAGGTCCTGAGCCTGGACAAGAACTACCTGCTGGTGGATCCGGCCACGgccgcagcagctgcagccgccGCTGGCGGGGATCCGGGGCtcgcccaccaccaccagctgACCAACGGCAGCATCGTTGATGCCAAGACCGGACAGACAGTGCTGACCGCCGGATCTGCGGCGGCCAAGTCGCACTTCAGCTCGATCGGAGCACTGCACCTCACGCAAGAGGAGTGCAACGAGATCCTGATCAAGCGCGCCATCGCTGCCGGCCACCATCAGACGCACACGATCACCGCTGCCGACGGAACCCATCACCATGCGTCCGGCGGGACACCAAGTGACATACTTCCTGGTATTTCAGTTCAAGTACAGAAAGTAATACAAGGACTGGAGGATAACGAGGACTCGCAGGGCGAAGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAGTTGTCCCCGAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACGGACGCCACCATCAAGAAGGAACGCCCGTACAGTTGCGACGAGTGCGGCAAGTCCTTTCTGCTCAAGCATCATCTGACAACCCACGCACGCGTGCACACAGGTGGTGAACGCCCCCACATCTGCACCCACTGCGGCAAGAGCTTCGCGCACAAGCACTGTCTCAACACTCACCTGCTCCTTCACTCCACGGAGCGACCTTATCAGTGCCAGGAGTGCAAGAAGAGTTTCACCCTCAAGCACCATCTGCTGACCCACTCGCGTGTCCACAGCCGCGAGCGACCGTTCGTCTGCCAGGAGTGTGGGCGCGCCTTTCCGCTGAAGCGACACCTGGTCACGCACAGCAAGTTTCACGCCGGCGAGCGACCGTATGTCTGCGAGGAATGCGGTGAGAGCTTTGCCCAGGAAAACCACCTGATTATGCACTCGCGCTTCCATGGCTCATTGAATCCATTTGTTTGTGCCGAATGCGGAGCTTCGTTTCCACGCAAGTTCCAATTGGTTAACCACGGACGTATTCACGGCAAAATCCCCCACTCGTGCACTGTGTGCGGCAAAGAGTTTCTACAAAAGCGAACGCTAGTTTCCCACATGAGGCGCGTACATACTGGCGAGCAGGCGCATCCCTGCGTCAGCTGCGGCGAGGGATTCCTCACCAAGGCCGAGCTCCATCAGCATGTGAGGACGGCGCACAATGGCGTCAATCCAAACACAAGCAGTGCCACCATCATAGCCAATCAGCAGCAGCTACAACAGGCCCATCATCACCAGGCTGGACAACAGACGCATCCGCAGACCATAACAGTGGTGAGCAATCCGGGCAACTCTACGTTGCTAACTGTCTCCACCACGGATGCCAATGGCGTGGCACGGCCGCAGTTTGTGTGCCGCGAGTGCGGCAGCGCTTTTAACAGCCGAGAGGCCTTGGCACTTCACTTGCGCCTTCACACTGGCGACAAGAGCCTAATGACAGATCTGTGTGCCTTGACAGCCGCGCTGCCGGGACACTTTTTGAGCACGGCCAGTCTGAATCCGGGCACCGTGGTTACGGCCAACCCGAATCTGGTGGGCCAGAGCCCTGTGCCAGTCCAGATCATATCGTCCACCGGTCAGGTTATGTCGCAGACCACACTGGTGCAGGCCGCCAACTCGACCCATCCCCAGGCAGTGGTCACTGCGGTGCCAACGATGCCCGTGCAcggtcagcagcagcatctgcagcacgtggcccagcagcagcagcaacagcagcaacaacagcagcaacagcagcagcacgtcGTCTCCGTGGCGCCGGCCAACAAGCCGAAGTCTCATTTCTGCGCCAGCTGCGGCAAGGGATTCGCGGCCAAGCACGGGCTCATGCAGCATAATCGGCGGCACCCGAACGGCGGATGCACGGTGCGCACACACGTGTGCGAGTGCGGCAAGGCCTTCTTCCAGAAGAACCACCTGATGCTGCATCAGCGCCAGCATCTGGAGACGAAGCCAGCCATATCGCAGCAACAGGAGGCCTCTGCCCAGCAGCAACTGGCGGCTGCCGGCGAACAGCAACAGGTGCAGGTGCAGATAATGCCCGATGGCCAGATTCACGGAAAGGTGATCAAGTACGAGATCTGCCGCAGCGTGTTGCCGGAGgatcagcagcaggagcagggggACATGAGCGCGGACTAA
- Protein Sequence
- MCAAQNPPPFGYTWGFADNGSRAAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKEVKGLTAGGKNNVVRRMFVVNDPSFPPGTQRVITAGGASTVVKKQDPNQQVLSLDKNYLLVDPATAAAAAAAAGGDPGLAHHHQLTNGSIVDAKTGQTVLTAGSAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHHQTHTITAADGTHHHASGGTPSDILPGISVQVQKVIQGLEDNEDSQGEAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICTHCGKSFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRTAHNGVNPNTSSATIIANQQQLQQAHHHQAGQQTHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHGQQQHLQHVAQQQQQQQQQQQQQQQHVVSVAPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEASAQQQLAAAGEQQQVQVQIMPDGQIHGKVIKYEICRSVLPEDQQQEQGDMSAD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00481685;
- 90% Identity
- iTF_00494559;
- 80% Identity
- -