Dper008761.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila persimilis
Gene Symbol
-
Assembly
GCA_003286085.2
Location
NW:19247338-19256372[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00023 0.013 15.6 3.4 1 23 295 317 295 317 0.98
2 11 0.0012 0.068 13.3 10.4 1 23 324 346 324 346 0.96
3 11 0.00012 0.0065 16.5 6.5 1 23 352 374 352 374 0.98
4 11 0.00052 0.029 14.5 1.6 1 23 380 402 380 402 0.95
5 11 2.5e-05 0.0014 18.6 0.5 1 23 408 430 408 430 0.97
6 11 2.5e-05 0.0014 18.7 0.1 1 23 436 458 436 458 0.98
7 11 0.00014 0.0079 16.3 2.0 1 23 463 486 463 486 0.97
8 11 0.059 3.3 8.0 0.3 1 23 492 515 492 515 0.94
9 11 0.00019 0.011 15.9 0.1 1 23 580 602 580 602 0.98
10 11 0.017 0.97 9.7 2.7 1 23 719 741 719 741 0.95
11 11 0.005 0.28 11.4 4.9 5 23 754 772 746 772 0.92

Sequence Information

Coding Sequence
ATGTGCGCCGCCCAGAACCCACAGCCGCCCTTCGGCTACACCTGGGGCTTCGCAGACAACGGCAGCCGCACCGCCGAATCGGTTCTGGAAATATCGCCCAACATAAACTACACCGTCAGTGGGGAATCGATGCCCTATCTGCTGTCCACGGATGGATCATTGGCCGTACAAAAGGATGTCAAAGGTGCTCTAACCGGCAATAAGGGGAATGTTGTGCGTCGCATGTACGTTGTGAACGATCCTTCGTTTCCGCCCGGTACACAGAGAGTAATTACCACTGGGGGAGGCTCGTCGGTAGTCAAGAAACAGGATTCGCAGCAGCAGGTGCTGAGCCTGGACAAGAACTATCTCCTGGTCGATCAGGCAactgccgcagcagcagcagccgcggCTGCCGGGGATCCCTCGGTTGCCCACCACCACACATTGACCAACGGTAGTATTGTCGATGCTAAGACCGGACAGACGGTGCTGACGGCGGGCTCCGCGGCTGCAAAGTCGCACTTTGGGTCAATTGGGGCGCTGCACCTCACCCAAGAGGAGTGCAACGAGATCCTGATTAAGCGCGCCATCGCTGCCGGCCACCATCAGACGCACACAATCACCGCTGCCGACGGATCGCATCATCATAGCTCCGCGTCTGGCGCGACACCAAGTTTCTGTTCCGTTGGCGGCGCAACAACACTCTTAGGTGACATACTTCCTGGTATTTCAGTTCAAGTCCAGAAAGTAATACAAGGACTCGAAGAGAACGAGGACTCGCAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAGTTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACGGACGCCACCATCAAGAAGGAACGCCCGTACAGTTGTGACGAGTGCGGCAAGTCCTTTCTGCTCAAGCATCATTTGACAACACACGCACGCGTGCACACAGGTGGTGAGCGACCCCATATCTGTTCCCATTGCGGCAAGAGCTTTGCGCACAAACACTGTCTGAACACGCATCTACTGCTGCATTCAACCGACCGACCCTACCAGTGCCAGGAGTGCAAGAAGAGCTTCACCCTTAAGCATCATCTGTTGACGCACTCGCGCGTCCACAGCCGAGAGCGACCCTTCGTGTGCCAGGAGTGCGGACGTGCCTTCCCACTCAAGCGGCACCTGGTCACGCACAGCAAATTCCACGCCGGCGAACGTCCATACGTCTGCGAGGAATGCGGTGAGAGCTTTGCCCAGGAAAACCATCTTATTATGCACTCGCGCTTCCATGGTTCATTGAATCCATTTGTTTGCGCTGAGTGCGGTGCCTCGTTTCCACGCAAGTTCCAGTTGGTGAATCACGGACGCATACACGGCAAGATTCCCCACTCCTGCACCGTTTGCGGAAAAGAGTTTTTACAGAAGCGAACGCTAGTTTCCCACATGAGACGTGTACACACCGGCGAGCAGGCGCATCCCTGCGTCAGCTGCGGCGAGGGATTCCTCACCAAGGCTGAGCTGCACCAGCACGTGCGGGCAGCGCACAATGGCGTCAATCCCAACACGAGCAGTGCCACCATCATTGCCAACCAACAGTTTATCGATTTcaagcagctgcaacagcccCACCACCATCCGGGACAGCATCCGCAGACGATCACCGTCGTGAGTAACCCGGGCAACTCTACGCTTCTCACGGTCTCCACCACGGATGCCAATGGTGTGGCGCGTCCGCAGTTCGTTTGCCGCGAGTGCGGCAGCGCCTTCAACAGTCGCGAGGCCTTGGCTTTGCATTTGCGACTGCACACCGGCGATAAGAGTCTGATGACCGATTTGTGCGCCTTGACGGCAGCGCTGCCGGGTCACTTCTTGAGCACGGCCAGCCTGAACCCGGGCACTGTGGTGACAGCCAATCCGAATTTGGTGGGCCAGAACCCAGTGCCCGTGCAGATCATATCGTCCACCGGCCAGGTTATGTCGCAGACTACGCTGGTGCAGGCCGCCAACTCGACCCATCCGCAGGCCGTAGTCACTGCCGTGCCAACGATGCCCGTTCATCAGCAACAGCACATGCAGCATGTtgcccagcaacaacaacagcagcagcagcaacagcacgtGGTCAATGTGGTGCCGGCCAATAAGCCCAAGTCGCATTTCTGCGCCAGCTGTGGCAAGGGATTCGCCGCCAAACACGGCCTCATGCAGCACAACCGCCGCCACCCGAACGGCGGCTGTACGGTGCGCACTCACGTCTGCGAGTGCGGAAAGGCCTTCTTCCAGAAGAACCATCTAATGCTGCACCAGCGCCAGCACTTGGAGACGAAGCCAGCCATATCACAGCAACAGgagcagcaacaacaggagGCGGCCGTGGCAGCGTCAGCGTCTGGACAGCAACCGGTGCAGGTGCAGATCCTGCCCGATGGCCACATACACGGCAAGGTCATCAAGTACGAGATCTGCCGCAGTGTGCTGCCAGAGGATCAGGCCACagcacagcaacagcagcaggcaggcatGGATGTGGAGTAG
Protein Sequence
MCAAQNPQPPFGYTWGFADNGSRTAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGALTGNKGNVVRRMYVVNDPSFPPGTQRVITTGGGSSVVKKQDSQQQVLSLDKNYLLVDQATAAAAAAAAAGDPSVAHHHTLTNGSIVDAKTGQTVLTAGSAAAKSHFGSIGALHLTQEECNEILIKRAIAAGHHQTHTITAADGSHHHSSASGATPSFCSVGGATTLLGDILPGISVQVQKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICSHCGKSFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRAAHNGVNPNTSSATIIANQQFIDFKQLQQPHHHPGQHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQNPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHQQQHMQHVAQQQQQQQQQQHVVNVVPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEQQQQEAAVAASASGQQPVQVQILPDGHIHGKVIKYEICRSVLPEDQATAQQQQQAGMDVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00481685;
90% Identity
iTF_00603515;
80% Identity
-