Basic Information

Insect: Drosophila eugracilis
Gene Symbol: -
Assembly: GCA_018153835.1
Location: NW:43373-52331[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00019 0.012 15.7 3.4 1 23 280 302 280 302 0.98

2 11 0.00093 0.059 13.5 10.5 1 23 308 330 308 330 0.96

3 11 9.3e-05 0.0059 16.7 6.5 1 23 336 358 336 358 0.98

4 11 0.00042 0.027 14.6 1.6 1 23 364 386 364 386 0.95

5 11 2e-05 0.0013 18.7 0.5 1 23 392 414 392 414 0.97

6 11 2e-05 0.0013 18.8 0.1 1 23 420 442 420 442 0.98

7 11 0.00011 0.0072 16.4 2.0 1 23 447 470 447 470 0.97

8 11 0.0092 0.58 10.4 0.6 1 23 476 499 476 499 0.96

9 11 0.00015 0.0097 16.0 0.1 1 23 562 584 562 584 0.98

10 11 0.014 0.88 9.8 2.7 1 23 707 729 707 729 0.95

11 11 0.0041 0.26 11.5 4.9 5 23 742 760 734 760 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00019	0.012	15.7	3.4	1	23	280	302	280	302	0.98
2	11	0.00093	0.059	13.5	10.5	1	23	308	330	308	330	0.96
3	11	9.3e-05	0.0059	16.7	6.5	1	23	336	358	336	358	0.98
4	11	0.00042	0.027	14.6	1.6	1	23	364	386	364	386	0.95
5	11	2e-05	0.0013	18.7	0.5	1	23	392	414	392	414	0.97
6	11	2e-05	0.0013	18.8	0.1	1	23	420	442	420	442	0.98
7	11	0.00011	0.0072	16.4	2.0	1	23	447	470	447	470	0.97
8	11	0.0092	0.58	10.4	0.6	1	23	476	499	476	499	0.96
9	11	0.00015	0.0097	16.0	0.1	1	23	562	584	562	584	0.98
10	11	0.014	0.88	9.8	2.7	1	23	707	729	707	729	0.95
11	11	0.0041	0.26	11.5	4.9	5	23	742	760	734	760	0.92

Sequence Information

Coding Sequence: ATGTGCGCCGCCCAGAATCCGCCGCCCTTCGGCTATACCTGGGGCTTTGCGGACAACAGCAGCCGCACCGCCGAATCGGTACTGGAGATATCGCCTAACATCAACTATACGGTCAGCGGGGAGTCGATGCCCTACCTGTTATCGACGGATGGATCATTGTCCGTTCAAAAGGATGTCAAAGGCCTTACAGCTGGCGGTAAAAATAATGTCGTTCGTCGTATGTTTGTCGTAAACGATCCATCATTTCCGCCTGGAACACAAAGAGTTATAACCGCCGGTGGAGCATCGACGGTGGTCAAGAAACAGGACCCAAATCAGCAGGTCCTGAGCCTCGACAAGAACTATCTGTTAGTAGATCCGGCCACAgccgcagcagctgcagccgcTGCTGGTGGGGATCCGGGGCTCGCCCACCATCACACGTTGACCAACGGCAGCATTGTTGATGCCAAGACCGGACAGACGGTGCTAACTGCCGGATCTGCGGCGGCCAAGTCGCACTTCAGCTCGATCGGAGCACTGCATCTCACGCAAGAGGAGTGCAACGAGATCCTGATCAAGCGCGCCATCGCTGCCGGCCACCATCAGACGCACACAATCACCGCTGCCGACGGATCCCATCACCATGCGTCCGGCGGGACACCAAGTGACATACTTCCTGGTATTTCAGTTCAAGTACAGAAAGTAATACAAGGACTAGAGGATAACGAGGACTCACAGGGCGAAGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAGTTGTCCCCGAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACGGACGCCACCATTAAGAAGGAACGCCCGTACAGTTGCGACGAGTGCGGCAAGTCCTTTCTGCTCAAGCATCATTTGACAACCCACGCACGCGTGCACACAGGTGAACGGCCCCACATCTGCACCCATTGCGGCAAGAGCTTCGCGCACAAGCACTGTCTCAACACTCACCTGCTGCTTCACTCCACGGAGAGACCTTATCAGTGCCAGGAGTGCAAGAAGAGCTTCACCCTCAAGCACCATCTGCTGACCCATTCGCGGGTCCACAGCCGAGAGAGACCCTTTGTCTGCCAGGAGTGCGGACGCGCCTTTCCGCTTAAGCGACACCTGGTCACGCACAGCAAGTTCCACGCCGGCGAGCGGCCGTATGTCTGTGAGGAATGCGGTGAGAGCTTTGCCCAGGAGAACCACCTGATTATGCACTCGCGCTTCCACGGTTCATTGAATCCATTTGTTTGTGCTGAATGCGGAGCTTCGTTTCCACGAAAGTTCCAATTGGTTAACCACGGACGTATTCACGGCAAAATCCCCCACTCGTGCACCGTGTGCGGCAAGGAGTTTCTACAAAAGCGAACACTAGTTTCCCACATGAGGCGCGTACATACTGGAGAGCAGGCGCATCCCTGTGTCAGCTGCGGCGAGGGATTCCTCACCAAGGCCGAGCTGCATCAGCATGTGAGGACGGCTCACAATGGAGTCAATCCCAACACGAGCAGTGCCACCATAATAGCCAATCAGCAGCAGCTGCAACAGGCCCATCATCATCAGGCCGGTCAGCAGACGCATCCGCAGACCATAACCGTGGTAAGCAATCCTGGTAACTCTACGTTGCTGACTGTTTCCACCACGGATGCCAATGGTGTGGCACGTCCGCAGTTTGTTTGCCGGGAATGTGGTAGCGCTTTTAATAGCCGAGAGGCCTTGGCACTTCATTTGCGCCTACACACTGGCGACAAGAGCCTAATGACAGATCTGTGTGCCTTGACAGCCGCGCTGCCGGGTCATTTCTTGAGCACGGCAAGCTTGAACCCGGGCACTGTGGTCACGGCCAATCCGAATCTGGTTGGTCAGAGCCCTGTGCCAGTGCAGATCATATCGTCCACCGGTCAGGTGATGTCTCAGACCACGCTGGTGCAGGCCGCCAATTCGACCCATCCCCAAGCTGTGGTCACCGCGGTGCCTACGATGCCCGTGCACGGTCAGCAACAGCACCTGCAGCACGtggcccagcagcagcagcaacaacagcaacagcagcaacaacaacagcagcatgTCGTCTCTGTGGCGCCGGCCAATAAGCCGAAGTCCCATTTCTGTGCCAGCTGCGGCAAGGGATTCGCCGCCAAGCACGGACTCATGCAGCACAATCGGCGTCACCCGAACGGCGGATGCACGGTGCGCACCCACGTGTGTGAATGCGGCAAGGCCTTCTTCCAGAAGAACCACCTGATGCTGCACCAGCGCCAGCATTTGGAGACGAAGCCAGCCATATCGCAGCAACAGCTTGTTGTACCAACTACTTCTTACTAA
Protein Sequence: MCAAQNPPPFGYTWGFADNSSRTAESVLEISPNINYTVSGESMPYLLSTDGSLSVQKDVKGLTAGGKNNVVRRMFVVNDPSFPPGTQRVITAGGASTVVKKQDPNQQVLSLDKNYLLVDPATAAAAAAAAGGDPGLAHHHTLTNGSIVDAKTGQTVLTAGSAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHHQTHTITAADGSHHHASGGTPSDILPGISVQVQKVIQGLEDNEDSQGEAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGERPHICTHCGKSFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRTAHNGVNPNTSSATIIANQQQLQQAHHHQAGQQTHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHGQQQHLQHVAQQQQQQQQQQQQQQQHVVSVAPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQLVVPTTSY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481685;
90% Identity: iTF_00594698;
80% Identity: -