Basic Information

Insect: Drosophila lacteicornis
Gene Symbol: -
Assembly: GCA_008044355.1
Location: VNKF01001381.1:10391-18512[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00019 0.015 15.8 3.4 1 23 272 294 272 294 0.98

2 10 0.00092 0.076 13.6 10.5 1 23 301 323 301 323 0.96

3 10 9.3e-05 0.0076 16.7 6.5 1 23 329 351 329 351 0.98

4 10 0.00042 0.035 14.6 1.6 1 23 357 379 357 379 0.95

5 10 2e-05 0.0017 18.8 0.5 1 23 385 407 385 407 0.97

6 10 2e-05 0.0016 18.8 0.1 1 23 413 435 413 435 0.98

7 10 0.00011 0.0093 16.4 2.0 1 23 440 463 440 463 0.97

8 10 0.0091 0.75 10.4 0.6 1 23 469 492 469 492 0.96

9 10 0.00015 0.012 16.0 0.1 1 23 553 575 553 575 0.98

10 10 0.0041 0.33 11.6 4.9 5 23 660 678 652 678 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00019	0.015	15.8	3.4	1	23	272	294	272	294	0.98
2	10	0.00092	0.076	13.6	10.5	1	23	301	323	301	323	0.96
3	10	9.3e-05	0.0076	16.7	6.5	1	23	329	351	329	351	0.98
4	10	0.00042	0.035	14.6	1.6	1	23	357	379	357	379	0.95
5	10	2e-05	0.0017	18.8	0.5	1	23	385	407	385	407	0.97
6	10	2e-05	0.0016	18.8	0.1	1	23	413	435	413	435	0.98
7	10	0.00011	0.0093	16.4	2.0	1	23	440	463	440	463	0.97
8	10	0.0091	0.75	10.4	0.6	1	23	469	492	469	492	0.96
9	10	0.00015	0.012	16.0	0.1	1	23	553	575	553	575	0.98
10	10	0.0041	0.33	11.6	4.9	5	23	660	678	652	678	0.92

Sequence Information

Coding Sequence: ATGTGCGCCGCCCAGAATCCGCCGCCCTTCGGCTATACCTGGGGCTTTGCAGACAACGGCAGCCGCAACGCCGAATCTGTCCTGGAGATATCGCCGAACATCAACTACACGGTCAGCGGGGAGTCGATGCCCTATTTGCTATCGACGGATGGATCGTTGGCCGTGCAAAAAGATGTCAAAGCGCTCACAGCTGCTGGCAATAAGAATGTCGTTCGTCGGATGTTCGTGGTAAACGATCCATCGTTTCCACCAGGGACACAGAGGGTAATCACCGCCGGAGGATCATCGACGGTGGTGAAGAAGCAGGACGCAAATCAGCAGGTGTTGAGCCTGGATAAGAACTATCTGCTCGTGGATCCCGccacggcggcagcagctgcagcggcagcgggcGGCGATCCGTCGGTGGCGCATCATCACCAGCTGGCGAACGGCAGCATTGTCGATGCCAAGACCGGACAGACGGTGCTAACCGCCGGCTCGGCGGCCGCCAAGTCGCACTTCAGCTCCATTGGGGCGCTGCATCTAACGCAGGAGGAGTGCAACGAGATCCTGATCAAGCGCGCCATCGCTGCCGGCCATCATCAGACGCACACGATCACCACTGCCGATGGGACGCACCATCATGCGTCTGGCGGGACACCAATTCAAGTACAGAAGGTAATCCAAGGACTCGAGGACAACGAGGACTCGCAGGGCGAAGCACCCAACCTAAAGCTGGAGCCAGGCACTTTGGAGCTGTCCCCGAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACGGACGCCACCATTAAGAAGGAACGCCCGTACAGTTGCGACGAGTGCGGCAAGTCCTTTCTGCTCAAGCATCATCTGACCACCCACGCACGCGTGCACACAGGTGGTGAACGGCCCCACATTTGCACCCATTGCGGCAAGAGCTTCGCGCACAAGCACTGTCTCAACAcgcacctgctgctgcactcGACGGAGCGACCGTATCAGTGCCAGGAGTGCAAGAAGAGCTTCACCCTCAAGCACCATCTGCTGACCCACTCGCGTGTCCATAGCCGAGAGCGGCCCTTTGTCTGCCAGGAGTGCGGGCGCGCCTTTCCGCTCAAGCGCCATCTGGTCACGCACAGCAAGTTTCACGCCGGCGAGCGGCCCTACGTCTGCGAGGAATGCGGTGAGAGCTTTGCCCAGGAGAATCACCTGATTATGCACTCGCGCTTCCATGGTTCATTGAATCCATTCGTTTGCGCCGAGTGCGGAGCCTCGTTTCCACGCAAGTTCCAGTTGGTTAATCACGGGCGCATTCACGGCAAGATCCCCCACTCGTGCACGGTGTGCGGCAAGGAGTTTCTACAGAAGCGAACGCTGGTCTCCCACATGAGACGCGTCCACACTGGCGAGCAGGCGCATCCCTGCGTCAGCTGCGGCGAGGGCTTCCTCACCAAGGCCGAGCTGCACCAGCACGTGAGGACGGCGCACAATGGCGTCAATCCCAATACGAGCAGTGCCACCATCATAGCCAATCAGCAGcagctgcaacagGCCCATCATCATCCCGGACAGACGCATCCGCAGACCATTACGGTGGTCAGCAATCCGGCCAACTCCACGCTGCTCACCGTCTCAACCACGGATGCTAATGGAGTGGCCCGGCCACAGTTTGTGTGCCGCGAGTGCGGCAGCGCCTTCAATAGCCGCGAGGCCTTAGCCCTTCACTTGCGCCTTCATACCGGCGACAAGAGTCTCATGACCGACTTGTGCGCCCTGACAGCCGCCCTGCCGGGTCACTTCTTGAGCACGGCCAGCCTGAATCCGGGCACCGTGGTCACGGCCAATCCGAATCTAGTTGGCCAGAGCCCCGTGCCCGTGCAGATCATATCGTCGACTGGGCAGGTGATGTCGCAGACCACGCTGCACGGCCTGATGCAGCACAATCGGCGGCATCCGAACGGCGGCTGTACAGTGCGCACccatgtgtgcgagtgcggCAAGGCCTTCTTCCAGAAGAACCACCTGATGCTGCACCAGCGCCAGCATCTGGAGACGAAGCCAGCCATATCGCAGCAACAGGAGACGTCCtctgcccagcagcagcagcagcaggcggccgGGTCGGCCAGCAGCGGTCAGCAGCCGGCGCAGGTTCAGGTGCAGATAATGCCCGATGGTCAGATTCACGGCAAGGTGATCAAGTACGAGATCTGCCGCAGCGTCTTGCCGGAggaccagcaacagcagcaggcggacATGGACGGGGAATAA
Protein Sequence: MCAAQNPPPFGYTWGFADNGSRNAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKALTAAGNKNVVRRMFVVNDPSFPPGTQRVITAGGSSTVVKKQDANQQVLSLDKNYLLVDPATAAAAAAAAGGDPSVAHHHQLANGSIVDAKTGQTVLTAGSAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHHQTHTITTADGTHHHASGGTPIQVQKVIQGLEDNEDSQGEAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICTHCGKSFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRTAHNGVNPNTSSATIIANQQQLQQAHHHPGQTHPQTITVVSNPANSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQETSSAQQQQQQAAGSASSGQQPAQVQVQIMPDGQIHGKVIKYEICRSVLPEDQQQQQADMDGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481685;
90% Identity: iTF_00492401;
80% Identity: -