g6492.t1
Basic Information
- Insect
- Drosophila pseudoobscura
- Gene Symbol
- -
- Assembly
- GCA_009870125.2
- Location
- CM020869.1:20030911-20037988[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00024 0.018 15.6 3.4 1 23 275 297 275 297 0.98 2 11 0.0012 0.094 13.4 10.4 1 23 304 326 304 326 0.96 3 11 0.00012 0.009 16.6 6.5 1 23 332 354 332 354 0.98 4 11 0.00054 0.041 14.5 1.6 1 23 360 382 360 382 0.95 5 11 2.6e-05 0.002 18.7 0.5 1 23 388 410 388 410 0.97 6 11 2.5e-05 0.0019 18.7 0.1 1 23 416 438 416 438 0.98 7 11 0.00015 0.011 16.3 2.0 1 23 443 466 443 466 0.97 8 11 0.061 4.6 8.1 0.3 1 23 472 495 472 495 0.94 9 11 0.0002 0.015 15.9 0.1 1 23 555 577 555 577 0.98 10 11 0.018 1.3 9.7 2.7 1 23 694 716 694 716 0.95 11 11 0.0052 0.39 11.4 4.9 5 23 729 747 721 747 0.92
Sequence Information
- Coding Sequence
- ATGTGCGCCGCCCAGAACCCACAGCCGCCCTTCGGCTACACCTGGGGCTTCGCAGACAACGGCAGCCGCACCGCCGAATCGGTTCTGGAAATATCGCCCAACATAAACTACACCGTCAGTGGGGAATCGATGCCCTATCTGCTGTCCACGGATGGATCATTGGCCGTACAAAAGGATGTCAAAGGTGCTCTAACCGGCAATAAGGGGAATGTTGTGCGTCGCATGTACGTTGTGAACGATCCTTCGTTTCCGCCCGGTACACAGAGAGTAATAACCACTGGGGGAGGCTCGTCGGTAGTCAAGAAACAGGATTCGCAGCAGCAGGTGCTGAGCCTGGACAAGAACTATCTCCTGGTTGATCAGGCaactgccgcagcagcagcagccgcggcTGCCGGGGATCCCTCGGTTGCCCACCACCACACATTGACCAACGGTAGTATTGTCGATGCTAAGACCGGACAGACGGTGCTGACGGCGGGCTCCGCGGCTGCAAAGTCGCACTTTGGGTCAATTGGGGCGCTGCACCTCACCCAAGAGGAGTGCAACGAGATCCTGATTAAGCGCGCCATCGCTGCCGGCCACCATCAGACGCACACAATCACCGCTGCCGACGGATCGCATCATCATAGCTCGGCGTCTGGCGCGACACCAATTCAAGTCCAGAAAGTAATACAAGGACTCGAAGAGAACGAGGACTCGCAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAGTTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACGGACGCCACCATCAAGAAGGAACGCCCGTACAGTTGTGACGAGTGCGGCAAGTCCTTTCTGCTCAAGCATCATTTGACAACACACGCACGCGTGCACACAGGTGGTGAGCGACCCCATATCTGTTCCCATTGCGGCAAGAGCTTTGCGCACAAACACTGTCTGAACACGCATCTACTGCTGCATTCAACCGACCGACCCTACCAGTGCCAGGAGTGCAAGAAGAGCTTCACCCTTAAGCATCATCTGTTGACGCACTCGCGCGTCCACAGCCGAGAACGACCCTTCGTGTGCCAGGAGTGCGGACGTGCCTTCCCACTCAAGCGGCACCTGGTCACGCACAGCAAATTCCACGCCGGCGAACGTCCATACGTCTGCGAGGAATGCGGTGAGAGCTTTGCCCAGGAAAACCATCTTATTATGCACTCGCGCTTCCATGGTTCATTGAATCCATTTGTTTGCGCTGAGTGCGGTGCCTCGTTTCCACGCAAGTTCCAGTTGGTGAATCACGGACGCATACACGGCAAGATTCCCCACTCCTGCACCGTTTGCGGAAAAGAGTTTTTACAGAAGCGAACGCTAGTTTCCCACATGAGACGTGTACACACCGGCGAGCAGGCGCATCCCTGCGTCAGCTGCGGCGAGGGATTCCTCACCAAGGCTGAGCTGCACCAGCACGTGCGGGCAGCGCACAATGGCGTCAATCCCAACACGAGCAGTGCCACCATCATTGCCAACCAACAGcagctgcaacagcccCACCACCATCCGGGACAGCATCCGCAGACGATCACCGTCGTGAGTAACCCGGGCAACTCTACGCTTCTAACGGTCTCCACCACGGATGCCAATGGTGTGGCGCGTCCGCAGTTCGTTTGCCGCGAGTGCGGCAGCGCCTTCAACAGCCGCGAGGCCTTGGCTCTGCATTTGCGACTGCACACCGGCGATAAGAGTCTGATGACCGATTTGTGCGCCTTGACAGCAGCGCTGCCGGGTCACTTCTTGAGTACGGCCAGCCTGAACCCGGGCACTGTGGTGACAGCCAATCCGAATTTGGTGGGCCAGAACCCAGTGCCCGTGCAGATCATATCGTCCACCGGCCAGGTTATGTCGCAGACTACGCTGGTGCAGGCCGCCAACTCGACCCATCCGCAGGCCGTAGTCACTGCCGTGCCAACGATGCCCGTtcatcagcaacagcacatgcaacatgttgcccagcaacaacaacagcagcagcagcaacagcacgtGGTCAATGTGGTGCCGGCCAATAAGCCCAAGTCGCATTTCTGCGCCAGCTGTGGCAAGGGATTCGCCGCCAAACACGGCCTCATGCAGCACAACCGCCGCCACCCGAACGGCGGCTGTACGGTGCGCACTCACGTCTGCGAGTGCGGAAAGGCCTTCTTCCAGAAGAACCATCTAATGCTGCACCAGCGCCAGCACTTGGAGACGAAGCCAGCCATATCACAGCAACAGgagcagcaacaacaggaggCGGCCGTGGCAGCGTCAGCGTCTGGACAGCAACCGGTGCAGGTGCAGATCCTGCCCGATGGCCACATACACGGCAAGGTCATCAAGTACGAGATCTGCCGCAGTGTGCTGCCAGAGGATCAGGCCAcagcacagcaacagcagcaggcaggcatgGATGTGGAGTAG
- Protein Sequence
- MCAAQNPQPPFGYTWGFADNGSRTAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGALTGNKGNVVRRMYVVNDPSFPPGTQRVITTGGGSSVVKKQDSQQQVLSLDKNYLLVDQATAAAAAAAAAGDPSVAHHHTLTNGSIVDAKTGQTVLTAGSAAAKSHFGSIGALHLTQEECNEILIKRAIAAGHHQTHTITAADGSHHHSSASGATPIQVQKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICSHCGKSFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRAAHNGVNPNTSSATIIANQQQLQQPHHHPGQHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQNPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHQQQHMQHVAQQQQQQQQQQHVVNVVPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEQQQQEAAVAASASGQQPVQVQILPDGHIHGKVIKYEICRSVLPEDQATAQQQQQAGMDVE*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00481685;
- 90% Identity
- iTF_00603515;
- 80% Identity
- -