Emi033317.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Euclidia mi
Gene Symbol
-
Assembly
GCA_944738845.2
Location
CALYKX020000317.1:1087557-1089905[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 4.4e-06 0.0012 21.3 4.4 1 23 8 31 8 31 0.95
2 21 0.00092 0.26 14.0 0.2 3 23 38 59 36 59 0.95
3 21 2.7e-05 0.0075 18.8 0.3 2 23 68 90 68 90 0.97
4 21 2.8e-06 0.00078 21.9 1.5 2 23 99 121 98 121 0.95
5 21 2.8e-05 0.0077 18.8 2.8 2 23 129 151 129 151 0.97
6 21 5.7e-05 0.016 17.8 2.4 2 23 160 182 159 182 0.95
7 21 1.7e-07 4.8e-05 25.7 1.3 1 23 188 211 188 211 0.98
8 21 0.0012 0.33 13.6 0.2 3 23 221 242 219 242 0.96
9 21 0.00073 0.2 14.3 0.6 3 23 258 279 256 279 0.96
10 21 6.8e-05 0.019 17.5 1.7 1 23 305 328 305 328 0.97
11 21 0.14 38 7.2 1.0 2 21 336 355 335 356 0.93
12 21 0.046 13 8.6 2.0 2 23 365 387 365 387 0.92
13 21 0.002 0.55 12.9 6.1 1 23 409 432 409 432 0.97
14 21 7.8e-06 0.0022 20.5 0.7 2 23 439 461 438 461 0.96
15 21 3.3e-05 0.0092 18.5 2.1 2 23 468 490 467 490 0.94
16 21 0.0065 1.8 11.3 2.2 1 23 496 519 496 519 0.97
17 21 0.17 46 6.9 7.1 2 23 527 549 527 549 0.95
18 21 1.8e-05 0.0051 19.3 0.8 1 23 556 579 556 579 0.98
19 21 0.12 33 7.4 2.1 1 23 586 609 586 609 0.88
20 21 0.033 9.3 9.1 2.8 5 23 626 645 623 645 0.90
21 21 2 5.5e+02 3.5 0.4 1 12 695 706 695 710 0.87

Sequence Information

Coding Sequence
ATGTATCACAACCAACTAGACTTTGTATGCGATTACTGCTCAAGAACTTTCACAAGGAAATACAACCTGCGGACGCATATAGAAAACTGCCACATCAATTCTTCCAGTCACTGTGACATCTGTGGTCAGAATTTCGGCAGTCCTGCTGGCTTGCAACTTCATCTATCCAGAGGCCATAATCATTATGGACAGCCATTCCCTGAGTGTGAATTGTGCGGAAGAATCTTTACTAGAAAACAGAATATCATGTCACATATGATAACAGTCCATCTGCAAGGATTAGGAGATGATATCAGATGTAGATTATGTGATAAACCATTCACAACTGAACGAAATTTGAAGAGGCATATGAATCAACAACACAACCCCGATATGGAATATCCTACATGCCATTACTGCACTAAAGTTTTTAGAGGTAAACACTCACTCATCGCTCATATTCAATCGGTACACAGTTCTCAAGAAAAAGATGTCATAAAATGTCACTTATGCGAAAAAGTTTACACCAATACCAGAAATTTGAAGCGGCACGTCGAAATGTTTCATGGTGAAAAAGGGGAATTTCGCTGTGATATTTGCCCTAAAGTGTATACGTCTAACCAGAGTCTAAGAAGGCATTTACGTACAACCCACAGTACTGATAGTCACGAACAATTTGGTTGCAGCTATTGTGGTAAAGTTATCATTGGGAAAGAGAATTTTGAAAGTCATATGCAATATAACCACTACCAACAAGTAGAGGTGGAAGTTAAAATTGAGAATGATATAATTTGTGAAATTTGCCACCAGTCTTACGAAGAAGAGACCCAATTAAGACAGCATATAAAGATGCAACACTCCTTTAAAGCGTTTTATAAATACTGTAAGAAGGTTCTTGTCAAGCAGTATGGCATGGAGTATGTTAATAATATTTACAATTGCGAGTTTTGTCAGCATTCTTTCCCTACTGTTTACGAATTAAAAGATCACATGAGAGTAAACCATGACACGGAATATTCGTTATCAACTTGCAATGTCTGCTTCAATAAGTTTTATAGTAAAGAGACTATGAAGGCTCATAAGAAAGTGTGTCTTCCACCAGCCGACGTCAATTCCTGCAGTCATTGTGATAAACTTTTCACTGATATATCAAGTTTAGAATTCCATTCAAGAATTTTCCATCCACAAGCTCAAATCGCAGACTCCAATATCAGTTCAACGAACATCGAAGAAGAAGTGAGCTGTTTCAAATGTGAGCACTGTGATCGTATGTACTACAGTGACAGGTCTTTGAAGCATCACATCAAATTGAAACATACGTCAGATGAGCAAGTAGAATGTACTTATTGCGGCAAAATATGCAGTAATAAGTACTATCTGGCCTCTCATATCAAAATTGTCCACAACAATGACACGTGGTCCCGTTGCGAATATTGCGATAAACAATTCAAATCTAAGAGAAATATTCGGAGGCATATCGAATACACGCATTTAGGGATGCAGAGATACAAATGTATCGAATGCGAGACGTTGTTTAAAGAAAAACGGAGTTTGAGGAAGCATGTTAGGACAAAACACCCAAATTCGGCTGCTTTCCCACAATGTCATATTTGCCACAAGCGGTTTGAATCTGCGAAGTCCTGCAAAATCCATCTGAAACTACTTCATTCTTTTAACATGAATACGTATCCTTGCCACCTCTGTTCAGTGTCATTTAGTTCTAATGAAGCTCTGACTATACACTTGAATACAAAACATTTGGCAGAAGACGAAATATACAAGTGCGAGCAATGCAATCTTGTTTTCAAGGGCCAAGAGCGCTTTGACAACCATAACGAAATCTGCCACGTGAACATACTACCTAATGTAAAGCAAAAAGTACTGCCGCGATGTATTCTGTGTATGAAAGACTTCAGCACACGGAAAACTCTAAAACGCCACATCAAGAAGTTCCATAATGACTTTGATGTTGACGAATTGGCCACTTTTGGCTCTCGAAGAAGAACTTTTACAATCGATTGCGAAGAATGCATCAAAAACTTTAGCGACGAGTTTTATTATAACATTTATCAGAAGATAAAGCATTTGCAGGATTCTGTTATTTTCAAATGCGAGTTCTGTCATACTGCCTATAATTCTTTGGAGTATGCTATACAGAGATATAAGATGGCTAATGGGGACGCCTCCAAGACTAAAACTATACTCAGTGAGTTGTGTACTACAGAAATGAGCGAAGAAGAAACTGAGTTTTCTGGTTTTGGATCACTGCATGAATTACCTGAAAGTACGACTGATGATATTCAGGTCAAAATGGAGCCAGCTAACATTCTATATGAGGATGATATCAAAATGGAGCCAATATCGCCTTAA
Protein Sequence
MYHNQLDFVCDYCSRTFTRKYNLRTHIENCHINSSSHCDICGQNFGSPAGLQLHLSRGHNHYGQPFPECELCGRIFTRKQNIMSHMITVHLQGLGDDIRCRLCDKPFTTERNLKRHMNQQHNPDMEYPTCHYCTKVFRGKHSLIAHIQSVHSSQEKDVIKCHLCEKVYTNTRNLKRHVEMFHGEKGEFRCDICPKVYTSNQSLRRHLRTTHSTDSHEQFGCSYCGKVIIGKENFESHMQYNHYQQVEVEVKIENDIICEICHQSYEEETQLRQHIKMQHSFKAFYKYCKKVLVKQYGMEYVNNIYNCEFCQHSFPTVYELKDHMRVNHDTEYSLSTCNVCFNKFYSKETMKAHKKVCLPPADVNSCSHCDKLFTDISSLEFHSRIFHPQAQIADSNISSTNIEEEVSCFKCEHCDRMYYSDRSLKHHIKLKHTSDEQVECTYCGKICSNKYYLASHIKIVHNNDTWSRCEYCDKQFKSKRNIRRHIEYTHLGMQRYKCIECETLFKEKRSLRKHVRTKHPNSAAFPQCHICHKRFESAKSCKIHLKLLHSFNMNTYPCHLCSVSFSSNEALTIHLNTKHLAEDEIYKCEQCNLVFKGQERFDNHNEICHVNILPNVKQKVLPRCILCMKDFSTRKTLKRHIKKFHNDFDVDELATFGSRRRTFTIDCEECIKNFSDEFYYNIYQKIKHLQDSVIFKCEFCHTAYNSLEYAIQRYKMANGDASKTKTILSELCTTEMSEEETEFSGFGSLHELPESTTDDIQVKMEPANILYEDDIKMEPISP