Lfle000293.1
Basic Information
- Insect
- Laspeyria flexula
- Gene Symbol
- -
- Assembly
- GCA_905147015.1
- Location
- LR989979.1:4621476-4623821[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 21 4.2e-06 0.00029 21.5 4.2 1 23 8 31 8 31 0.95 2 21 0.00018 0.012 16.4 0.2 3 23 38 59 36 59 0.95 3 21 1.9e-05 0.0013 19.5 0.3 2 23 68 90 68 90 0.97 4 21 0.00013 0.0092 16.8 4.2 2 23 99 121 98 121 0.94 5 21 1.2e-05 0.00083 20.1 2.8 2 23 129 151 129 151 0.97 6 21 6.5e-05 0.0045 17.8 2.4 2 23 160 182 159 182 0.95 7 21 1.4e-07 9.6e-06 26.2 1.2 1 23 188 211 188 211 0.98 8 21 0.033 2.3 9.3 0.5 1 23 219 242 219 242 0.94 9 21 0.0026 0.18 12.8 2.4 2 23 255 277 254 277 0.96 10 21 0.0002 0.014 16.2 1.6 1 23 303 326 303 326 0.96 11 21 0.27 19 6.4 0.8 2 22 334 354 333 354 0.94 12 21 0.061 4.2 8.4 3.9 1 23 362 385 362 385 0.92 13 21 0.001 0.069 14.1 5.5 1 23 407 430 407 430 0.97 14 21 3.5e-05 0.0024 18.6 0.3 2 23 437 459 436 459 0.96 15 21 3e-05 0.002 18.9 1.6 2 23 466 488 466 488 0.94 16 21 0.0074 0.51 11.3 2.2 1 23 494 517 494 517 0.97 17 21 0.27 19 6.4 4.7 2 23 525 547 525 547 0.95 18 21 5e-05 0.0035 18.1 2.0 1 23 554 577 554 577 0.97 19 21 1.2 82 4.4 1.5 1 23 584 607 584 607 0.86 20 21 0.0014 0.096 13.6 3.3 5 23 624 643 621 643 0.92 21 21 3.4 2.3e+02 2.9 0.2 1 12 693 704 693 707 0.87
Sequence Information
- Coding Sequence
- ATGTATCAAAATCAATTGGATTTTGTCTGCGATTACTGCTCAAGAACATTTACAAGAAAATACAATTTACAGACACACATCGAAAATTGTCATATCAACTCGTCAAGTCATTGTGACATATGCGACCAAAGTTTTGCGAGCCCGGCCGGTTTACAACTTCATCTATCTAGAGGTCATAATAACTACGGACAAGCCTTTCCAGAATGCGATCTATGCGGCAGAATCTTTACAAGAAAACAGAACATCACTTCACATATGATAACTGTACATCTTCAAGGACTTGGGGACGAAATAAAATGTCGATTTTGCAAGAAGACCTTCACAACTTTAAGAAATTTGAAGCGACATAAAAATCAATTACACAATCCGAATATAGAGTACCCTACTTGTCATTATTGTAACAAAGTGTTTAAGGGCAAACATTCATTAATTGCCCATATACAGTCCGTTCACAATATGAATGAGAAGGATGCGATAAAGTGTCATCTGTGTGAGAAGGTTTACACTAATACTCGGAATTTGAAGCGCCATGTTGAAATGTTTCACGGTGAAAAGGGCGAGTACCGTTGTGATATCTGCCCTAAAGTGTACACCTCAAATCAGAGCCTACGAAGGCATTTACGTACTACACATAGTACAGACAGTCAAGAACAATTCAATTGTGAATATTGCTACAAAATTATTATTGGAAAGGATAATTTTGAGAGCCACATACAATTTAATCACACTTCTGACATGAATATTAAAGTTGAAAATGATATTATGTGTGAGATATGTCATTTATCATTTGAAGAAGAATGCCAGTTACGTCAGCATATAAAGAAAGATCACTCTTTTAAAGCATTTTATCAATACTGTAAAAGCGTGTTGGTGAAGCAGTATGGAATGGAATATATTAACAATATATATAATTGTGAATTCTGTCAACATGCATTCTCAAGTGTTTACGAGTTAAAAGATCATATGAGAGCTACTCATGACACAGAATATCTTCTATCGACATGTAATGTATGTTTTAATAAATTCTACAGCAAAGAAACAATGGTAGCCCACAAAAGAAGATGTCTTCCACCACCAAATGTTCACTCGTGCAGTCACTGCGATAAACTATTCACTGATATATCAAGCCTTGAATTTCATTCTAGGATATTCCATCCGCAAGCTCAAATAGCAGATTCTAACATCACTTCAACGAATATAGATGAGGAAACAACGTCTTTTAAATGTGAACATTGTGACCGTGTATATTACAGTGACCGATCTTTGAAACATCATATAAAATTAAAACATACCACCGACGAAGAAGTTGAATGTGAAATATGTGGTAAAATATGCAGCAATAAATATTATCTTGCATCTCATGTGAAAATAGTACATAATAATGACACTTTGGCCCGTTGTGAATATTGTGATAAAGAATTTAAATCAAAAAGAAATATTAGAAGACATATTGAGTATACACATCTTGGTATGCAGAGATACAAGTGTATTGAATGTGAGACCTTATTCAAAGAAAAACGAAGTCTTCGCAAGCATGTAAGGACTAAACACCCAAATTCAGCTGCGTTTCCTCAGTGTCATATATGTTATAAACGGTTTGAATCGGCAAGATCTTGTAAGATACATTTAAAATTACTACATTCTTTTAACATGAATACACACCCTTGCCATATTTGCTCAATGTCTTTTAGCTCAAATGAAGCTCTAAGTATTCATTTAAATACCAAACATTTAGCTGAAGATGAAATTTATAAATGTGAAGCATGCAACCTCGTTTTTAAAGGACAAGAGAGATTTGATAGTCATAACGAAGTGTGTCATATAAGTTTGATGCCGAACATCAAGCAAAAAGTGTTACCTAGATGTATTTTGTGCACGAAGGATTTTAGCACAAAAAAAACGCTCAAACGGCATATTAAAAAGTTCCATAGCGAATTTGATGTGGATGAGCTAGCTACATTCGGTTCAAGAAGGAGATCTTTTAGTGTAGACTGCGATAACTGTATAAAAAACTTCAATGACGATTTTCATTTTAATGTTTATCAAAAAATAAAACATTTAACAGATAGTGTTGTTTTTCAATGTGAGACTTGTCAAACTGCATATAATTCTTTGGAATATTCTATTCAGAAGTACAAGTTGACTCACACTGAGGGAGCAAAGACAAAGATGATACTAAGTGAATTATGTACTACTGAAATGAGTGATGAGGAGAATGAGTTTTCTGGGTTTGGCTCCTTACATCAGGTGCCAGAGAGTACTACGTCTGAATTTAGTATTAAAAATGAACCGGATGAAACATTTATGTCGCAAGATGAGGTCAAAATGGAGCCCTTGTCGCCATGA
- Protein Sequence
- MYQNQLDFVCDYCSRTFTRKYNLQTHIENCHINSSSHCDICDQSFASPAGLQLHLSRGHNNYGQAFPECDLCGRIFTRKQNITSHMITVHLQGLGDEIKCRFCKKTFTTLRNLKRHKNQLHNPNIEYPTCHYCNKVFKGKHSLIAHIQSVHNMNEKDAIKCHLCEKVYTNTRNLKRHVEMFHGEKGEYRCDICPKVYTSNQSLRRHLRTTHSTDSQEQFNCEYCYKIIIGKDNFESHIQFNHTSDMNIKVENDIMCEICHLSFEEECQLRQHIKKDHSFKAFYQYCKSVLVKQYGMEYINNIYNCEFCQHAFSSVYELKDHMRATHDTEYLLSTCNVCFNKFYSKETMVAHKRRCLPPPNVHSCSHCDKLFTDISSLEFHSRIFHPQAQIADSNITSTNIDEETTSFKCEHCDRVYYSDRSLKHHIKLKHTTDEEVECEICGKICSNKYYLASHVKIVHNNDTLARCEYCDKEFKSKRNIRRHIEYTHLGMQRYKCIECETLFKEKRSLRKHVRTKHPNSAAFPQCHICYKRFESARSCKIHLKLLHSFNMNTHPCHICSMSFSSNEALSIHLNTKHLAEDEIYKCEACNLVFKGQERFDSHNEVCHISLMPNIKQKVLPRCILCTKDFSTKKTLKRHIKKFHSEFDVDELATFGSRRRSFSVDCDNCIKNFNDDFHFNVYQKIKHLTDSVVFQCETCQTAYNSLEYSIQKYKLTHTEGAKTKMILSELCTTEMSDEENEFSGFGSLHQVPESTTSEFSIKNEPDETFMSQDEVKMEPLSP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00677880;
- 90% Identity
- -
- 80% Identity
- -