Basic Information

Gene Symbol
-
Assembly
GCA_003709505.1
Location
PKRV01000444.1:148923-151259[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 3.5e-06 0.00022 21.5 4.2 1 23 8 31 8 31 0.95
2 21 0.00024 0.015 15.8 0.2 3 23 38 59 36 59 0.95
3 21 5.3e-06 0.00033 21.0 0.3 2 23 68 90 68 90 0.97
4 21 8.9e-07 5.5e-05 23.4 2.8 2 23 99 121 98 121 0.95
5 21 0.00024 0.015 15.8 4.6 2 23 129 151 129 151 0.97
6 21 1.8e-05 0.0011 19.3 2.5 2 23 160 182 159 182 0.96
7 21 7.9e-08 4.9e-06 26.7 0.8 1 23 188 211 188 211 0.98
8 21 0.33 21 5.9 0.5 1 23 219 242 219 243 0.95
9 21 0.0012 0.072 13.6 0.2 3 23 257 278 255 278 0.94
10 21 1.5e-05 0.00095 19.6 0.7 1 23 304 327 304 327 0.97
11 21 0.015 0.94 10.1 2.2 2 23 364 386 364 386 0.95
12 21 0.0063 0.39 11.3 5.9 1 23 409 432 409 432 0.97
13 21 0.00015 0.0094 16.4 1.0 3 23 440 461 440 461 0.98
14 21 3.2e-05 0.002 18.6 2.1 2 23 468 490 467 490 0.94
15 21 0.00024 0.015 15.8 2.2 1 23 496 519 496 519 0.98
16 21 0.16 9.9 6.9 7.1 2 23 527 549 527 549 0.95
17 21 1.8e-05 0.0011 19.3 0.8 1 23 556 579 556 579 0.98
18 21 0.015 0.91 10.2 0.4 1 20 586 605 586 609 0.88
19 21 0.0078 0.49 11.0 2.9 5 23 626 645 623 645 0.91
20 21 8.8 5.5e+02 1.4 0.1 3 17 667 681 665 682 0.87
21 21 3.2 2e+02 2.8 0.7 1 12 695 706 695 709 0.86

Sequence Information

Coding Sequence
atgtatcaaaatcaGCTGGACTTTGTCTGCGATTACTGCTCCAGGACATTCACAAGAAAATATAACCTACAAACACATATAGAAAACTGTCACATAAATTCTTCATCGCACTGCGATATTTGTGGACAGAGCTTTGGTAGTCCAGCCGGCTTACAACTCCATTTATCGAGAGGCCACAACAGTTATGCTCAACCATTCCCAGAATGTGATATATGTGGAagaatttttacaagaaaacaaaacatcaCATCTCACATGATCACAGTGCATTTACAAGGATTAGGTGACGATATACGGTGTAAATTGTGCAATAAGACCTTCACTACTGAGAGAAACTTGAAGAGGCATATGAACCAACAACATAATCCGTATGCAGAATATCCCACATGCTATTATTGTAACAAAACCTTTAAAGGAAAACACTCGCTCATTTCACACATTCATACAATCCATAATATAAGTGAAAAAGATGCCATAAAATGCCACTTATGTGAGAAAGTGTACACAAATACGAGGAATTTAAAGAGGCACATTGAAATGTTTCATGGAGAACGGGGTGAGTTCAAATGTGATATATGCCCTAAAGTGTATACTTCAAACCAGAGCTTAAGGAGGCATCTCCGCACAGCACACAGCACGGACAGTAATGAACAGTTTTCATGCAACTTGTgtgctaaaattattattggtaGAGAAAATTATGAAAGTCACTTACAGTATATACATCACTATGGAAGCGAATCTAAAATTAATGTCAGAGAAATAATTTGCGAAACGTGTCAACAGACATTTGAAGAAGAATCTCTATTGCGCcaacatataaaagaaaatcattctTTTAAAGCCTTTTATAAGTACTGTAGGAATGTTTTATTGAAACAGTATGGTTCTGAGTTCGTTAATAATGCGTATAATTGTGAATATTGTCGGCAAACGTTCCCAAGTGTCTACGAACTAAAAGACCATATGCGAATAAATCACGACACTGAATACTCTCTGTCGACTTGTAATGTATgttttaacaagttttattgTAAGGAAACTATGAGCGCCCACAAAAAAGTGTGTATACCCCCAACAAATGTGAATTCTTGCAGTCATTGCGACAAGTTATTCACTGATATTTCTAGTTTAGAATTCCATACAAGAATATTCCACCCCCAAGCGCAGATTGCGGACTCGAATATATCATCAACGAATATAGATGAAGATTTAGCTACTTCGTTCAAATGCGTACATTGTGATCGTATGTACTATAGCGACCGATCATTAAAACAtcatataaaattgaaacacaCTTCGGATGAGCAAGTAGGTTGTGAGTTTTGTGGGAAAATTTGCAGCAATAAATACTATCTAGCTTCCCACATCAAAATAGTGCACAACAATGATTCTTGGTCTCGTTGCGAATACTGCGATAAACAGTTCAAATCTAAACGGAATATTAGAAGGCATATTGAATACACACATCTAGGTATGCAAAGATACAAATGTGTCGAATGCGAGACGTTGTTTAAAGAGAAACGCAGCTTACGAAAACACGTCAGGACAAAGCATCCTAATTCAGCCGCATTCCCTCAGTGTCATATATGTCACAAACGGTTTGAATCGGCCAAGTCCTGTAAGATTCATCTTAAGCTGTTACATTCATTTAATATGAACACATATCCATGTCATTTATGCTCAGTATCATTCAGCTCTAACGAAGCTTTGACGATACAtctaaatacaaaacatttagcTGAAGATGAAATATACAAATGCGAGGAATGCAACCTCGTTTTCAGAGGACAAGAACGCTTTGACAGACACAACGGAGTGAGCCACGTCAATCTTGTGCCAAGTCTAAAGCAAAAACTATTACCTAGATGCATTTTGTGTTTAAAGGACTTTAGCACCCGTAAGACTCTAAAAAGGCATATCAAGAAGTTTCATAGCGAGTTCGATGTTGAGGAACTGGCTACTTTTGGGTCGCGAAGGAGGACCTTCACAATAGACTGCGAAGATTGTATCAAGAATTTCAGCGATGAGTTTCATTACAATGTGTACCAAAAAATAAAGCATTTGAAAGATTCGATTATATTCAAGTGTGAGAATTGTCATTCATCCTTTGGTTCCCTTGAATACGCTATTCAACGGTATAAGATTACGAATAGCGATGCTTGCAAGACCAAGGCAATTCTAAGCGAGCTTTGCACTACTGAAATGAGTGAGGAGTCTGAGTTTTCTGGTTTCGGTTCTCTGCATCAGCTCCCGGAGAGTACAACAAATGAATTCAACATTAAACAAGAGCCTTTAATGTATGAAGATATCAAAAAGGAACCCGTATCGCCTTAA
Protein Sequence
MYQNQLDFVCDYCSRTFTRKYNLQTHIENCHINSSSHCDICGQSFGSPAGLQLHLSRGHNSYAQPFPECDICGRIFTRKQNITSHMITVHLQGLGDDIRCKLCNKTFTTERNLKRHMNQQHNPYAEYPTCYYCNKTFKGKHSLISHIHTIHNISEKDAIKCHLCEKVYTNTRNLKRHIEMFHGERGEFKCDICPKVYTSNQSLRRHLRTAHSTDSNEQFSCNLCAKIIIGRENYESHLQYIHHYGSESKINVREIICETCQQTFEEESLLRQHIKENHSFKAFYKYCRNVLLKQYGSEFVNNAYNCEYCRQTFPSVYELKDHMRINHDTEYSLSTCNVCFNKFYCKETMSAHKKVCIPPTNVNSCSHCDKLFTDISSLEFHTRIFHPQAQIADSNISSTNIDEDLATSFKCVHCDRMYYSDRSLKHHIKLKHTSDEQVGCEFCGKICSNKYYLASHIKIVHNNDSWSRCEYCDKQFKSKRNIRRHIEYTHLGMQRYKCVECETLFKEKRSLRKHVRTKHPNSAAFPQCHICHKRFESAKSCKIHLKLLHSFNMNTYPCHLCSVSFSSNEALTIHLNTKHLAEDEIYKCEECNLVFRGQERFDRHNGVSHVNLVPSLKQKLLPRCILCLKDFSTRKTLKRHIKKFHSEFDVEELATFGSRRRTFTIDCEDCIKNFSDEFHYNVYQKIKHLKDSIIFKCENCHSSFGSLEYAIQRYKITNSDACKTKAILSELCTTEMSEESEFSGFGSLHQLPESTTNEFNIKQEPLMYEDIKKEPVSP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00677880;
90% Identity
iTF_00707186;
80% Identity
-