Dmen010434.1
Basic Information
- Insect
- Diaphora mendica
- Gene Symbol
- -
- Assembly
- GCA_949125395.1
- Location
- OX421313.1:9332145-9334487[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 4.5e-06 0.0006 21.5 4.2 1 23 8 31 8 31 0.95 2 20 0.0003 0.04 15.8 0.2 3 23 38 59 36 59 0.95 3 20 6.6e-06 0.00089 21.0 0.3 2 23 68 90 68 90 0.97 4 20 1.1e-06 0.00015 23.4 2.8 2 23 99 121 98 121 0.95 5 20 0.0003 0.041 15.8 4.6 2 23 129 151 129 151 0.97 6 20 5.5e-05 0.0074 18.1 1.0 2 23 160 182 159 182 0.96 7 20 1.3e-07 1.7e-05 26.4 0.7 1 23 188 211 188 211 0.98 8 20 0.077 10 8.2 0.5 1 23 219 242 219 243 0.96 9 20 0.0056 0.76 11.8 0.2 2 23 256 278 255 278 0.94 10 20 2.8e-05 0.0038 19.0 1.6 1 23 304 327 304 327 0.97 11 20 0.019 2.6 10.1 2.2 2 23 364 386 364 386 0.95 12 20 0.0078 1.1 11.3 5.9 1 23 409 432 409 432 0.97 13 20 0.00019 0.026 16.4 1.0 3 23 440 461 440 461 0.98 14 20 4e-05 0.0053 18.5 2.1 2 23 468 490 467 490 0.94 15 20 0.0003 0.041 15.8 2.2 1 23 496 519 496 519 0.98 16 20 0.2 27 6.9 7.1 2 23 527 549 527 549 0.95 17 20 2.2e-05 0.003 19.3 0.8 1 23 556 579 556 579 0.98 18 20 0.018 2.5 10.2 0.4 1 20 586 605 586 609 0.88 19 20 0.0098 1.3 11.0 2.9 5 23 626 645 623 645 0.91 20 20 2.4 3.3e+02 3.5 0.4 1 13 695 707 695 710 0.88
Sequence Information
- Coding Sequence
- atgtatgaaaatcaaCTGGACTTTGTCTGTGATTACTGCTCCAGAACATTCACAAGAAAATATAATCTACAAACTCATATAGAAAACTGTCACATAAATTCTTCATCACATTGCGATATTTGCGGACAAAGCTTTGGTAGTCCAGCCGGCTTACAACTCCATCTATCGAGAGGCCACAACAGCTATGCCCAACCGTTCCCAGAATGTGACATATGTGGTagaatttttacaagaaaacaAAACATCACATCTCACATGATCACCGTGCATTTACAAGGTTTAGGTGACGATATAAGGTGTAAATTGTGCAATAAGACCTTCACCACTGAGAGGAACTTGAAGAGGCATATGAACCAACAACATAATCCGCATGTAGAATATCCCACATGCTATTACTGTAATAAAACCTTTAAAGGAAAACACTCGCTCATTTCACATATCCATACAATCCATAACATCAGTGAAAAAGATGCGATAAAATGCTACTTGTGTGAAAAAGTGTACACAAACACGAGGAATTTGAAGAGGCACATTGAAATGTTTCATGGAGAACGGGGGGAGTACAAATGTGATGTATGCCCTAAAGTGTATACTTCAAACCAGAGTTTGAGGAGGCATCTTCGCACAGCACATAGCACGGACAGTAGCGAACAGTTTACATGCAACTTGTGTGCTAAAGTTATCGTTGGTAGAGAGAATTATGAAAGTCATTTACAGTATATACATCATTATGAAAGCGAATCTAAAATTTGTATCAAAGAACTAATTTGCGAATCGTGTGAACAGACATTCGAAGAGGAATCTCTATTGCGGCagcatataaaagaaagtcattCTTTTAAAGCTTTTTATAAGTACTGTAGGAATGTTTTATTGAAACAGTATGGTTCTGAGTTCGTTAATAATGTGTATAATTGTGAATATTGTCAGCACACGTTCCCAAGTGTGTACGAGCTAAAAGACCATATGCGGATAAATCATGACACTGAATACTCTCTCTCGacttgtaatgtatgtttttacaagttttattgTAAGGAAACTATGAGTGCCCACAAAAAAGTGTGTATACCCCCACCAAACGTGAATTCTTGCAGTCATTGCGACAAGTTGTTCACTGATATTTCTAGTTTAGAATTCCATACAAGAATATTCCACCCCCAAGCGCAGATTGCTGACTCGAATATATCTTCGACGAATATAGATGAAGATTTATCAAGTTCATTCAAATGCGTACATTGTGACCGTATGTATTATAGCGACCGATCTTTAAAACATCACATCAAATTGAAACACACTTCGGATGAGCAAGTGGGCTGTGAGTTTTGTGGGAAAATTTGCAGCAATAAATACTATCTCGCTTCACACATCAAAATAGTGCACAACAATGATTCTTGGTCTCGTTGCGAGTACTGCGATAAGCAGTTCAAATCTAAACGGAATATTAGAAGGCATATTGAATACACACATCTAGGTATGCAAAGATACAAATGCGTCGAATGCGAGACGTTGTTTAAAGAGAAACGCAGCTTACGAAAGCACGTGAGGACAAAACATCCTAATTCAGCCGCATTCCCTCAGTGTCATATATGTCACAAACGGTTTGAATCGGCCAAGTCCTGCAAGATTCATCTCAAGCTGTTACATTCGTTTAATATGAACACATATCCATGTCATTTATGCTCAGTATCGTTTAGCTCTAATGAAGCTTTGACGATACATCTGAATACAAAACATTTAGCTGAAGACGAAATATACAAATGCGAGGAATGCAATCTCGTCTTCAGAGGACAAGAACGGTTCGACAGACACAACGGAGTCAGCCACGTCAATCTTGTGCCAAATATTAAGCAAAAACTTTTACCTAGATGCATTCTGTGTTTGAAAGATTTCAGCACCCGCAAGACTCTAAAAAGACATATCAAAAAGTTTCATAACGAATTTGATGTTGACGAACTAGCTACTTTTGGGTCGAGAAGGAGGACTTTTACAATAGACTGCGAAGATTGTATCAAGAATTTCAGCGATGAGTTTTATTACAATGTGTAccaaaaaataaagcatttgaAAGATTCGATTATATTCAAGTGTGAGAATTGTCATTCATCATACAGTTCTCTTGAATATGCTATTCAAAGGTATAAGATTACGAATAGCGATGCTTGCAAGACAAAGGCAATTCTAAGCGAACTTTGTACTACTGAAATGAGTGAGGAGGAGTCAGAGTTTTCTGGTTTCGGTTCTCTGCATCAGCTCCCGGAGAGCACAACGAGTGAATTCAACATTAAACAAGAACCTATAATGTATGAAGATGTTATCAAAAGCGAACCTGTATCGCCTTAA
- Protein Sequence
- MYENQLDFVCDYCSRTFTRKYNLQTHIENCHINSSSHCDICGQSFGSPAGLQLHLSRGHNSYAQPFPECDICGRIFTRKQNITSHMITVHLQGLGDDIRCKLCNKTFTTERNLKRHMNQQHNPHVEYPTCYYCNKTFKGKHSLISHIHTIHNISEKDAIKCYLCEKVYTNTRNLKRHIEMFHGERGEYKCDVCPKVYTSNQSLRRHLRTAHSTDSSEQFTCNLCAKVIVGRENYESHLQYIHHYESESKICIKELICESCEQTFEEESLLRQHIKESHSFKAFYKYCRNVLLKQYGSEFVNNVYNCEYCQHTFPSVYELKDHMRINHDTEYSLSTCNVCFYKFYCKETMSAHKKVCIPPPNVNSCSHCDKLFTDISSLEFHTRIFHPQAQIADSNISSTNIDEDLSSSFKCVHCDRMYYSDRSLKHHIKLKHTSDEQVGCEFCGKICSNKYYLASHIKIVHNNDSWSRCEYCDKQFKSKRNIRRHIEYTHLGMQRYKCVECETLFKEKRSLRKHVRTKHPNSAAFPQCHICHKRFESAKSCKIHLKLLHSFNMNTYPCHLCSVSFSSNEALTIHLNTKHLAEDEIYKCEECNLVFRGQERFDRHNGVSHVNLVPNIKQKLLPRCILCLKDFSTRKTLKRHIKKFHNEFDVDELATFGSRRRTFTIDCEDCIKNFSDEFYYNVYQKIKHLKDSIIFKCENCHSSYSSLEYAIQRYKITNSDACKTKAILSELCTTEMSEEESEFSGFGSLHQLPESTTSEFNIKQEPIMYEDVIKSEPVSP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00677880;
- 90% Identity
- iTF_00707186;
- 80% Identity
- iTF_00441760;