Dmac011461.1
Basic Information
- Insect
- Drosophila macrospina
- Gene Symbol
- -
- Assembly
- GCA_035042075.1
- Location
- JAWNLW010000539.1:2745964-2751781[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.047 3.1 8.4 0.2 1 23 1288 1311 1288 1311 0.94 2 13 7.7 5e+02 1.4 0.2 1 23 1470 1492 1470 1492 0.91 3 13 0.00017 0.011 16.1 2.7 2 23 1495 1516 1495 1516 0.97 4 13 6.6e-05 0.0043 17.4 0.2 3 23 1524 1544 1522 1544 0.98 5 13 5.5e-07 3.6e-05 23.9 4.1 2 23 1551 1572 1550 1572 0.97 6 13 4.9 3.2e+02 2.0 0.4 5 23 1585 1603 1582 1603 0.95 7 13 1.3 84 3.9 5.4 3 23 1610 1631 1608 1631 0.93 8 13 0.14 9 6.9 0.2 2 23 1642 1662 1641 1662 0.96 9 13 5.3e-05 0.0034 17.7 0.4 1 19 1668 1686 1668 1690 0.95 10 13 1.5e-05 0.00098 19.4 0.5 1 23 1698 1720 1698 1720 0.98 11 13 9.9e-05 0.0064 16.8 7.6 1 23 1726 1748 1726 1749 0.96 12 13 0.00019 0.012 15.9 5.9 1 23 1754 1776 1754 1776 0.98 13 13 0.027 1.8 9.1 8.2 1 23 1782 1804 1782 1805 0.95
Sequence Information
- Coding Sequence
- ATGGTTGACAGTGTGCAGTGCCCCGTGTGCACTTTGTACCTGCACGCGGGCATGAATCTCTCTGATCATTTGGAGACGCATCCCAAGGAACAAGTCATCAAAGCCCTGGTGCAAATGACAATCGTTGGCAGCAATGCAATAGGCGGCGCCCTGGTGGCAGCTGCGCTCTCCACTGCCGGCAGTGGTGCATCATCAGACGGTGCCTCCTCCTCATCCCCGCCTGAAACTGATGTAAAaccagctgtggcagcaacagcaacagcaccatcagctgtagcagcagcagcaccagcagcagcaacgacagcagcacatccaccaccaccacccccaacaccaacagcaacaccaacaacaacaacaacattaaaatcaACAGCACCCAAAGCTGCATCATTGCTGGGAAacgcaagcagcaacagtagcaataacagcaacagtaacaataacaaattgagcAATCCACCGATTAAGGCAGTTAAAAGCGCGCCACCCTCGACTGAGGCGTCAGCCACCACATCCATTACACCCACCATTAGCAGTGTGGCCGCTGCCTATCCTCCATCGTTGACATCCGACTATCGCTACgatcagcagcaccagcagcagcaacaacaacagactcCGCCGCCGGCAACGCTTCATGGCTTTCCACGTGGCGCAACAACGATGCTGGTAATACCAcaagcaacacaacagcagcatcatttCCTGGCGACCCAACAGCCTGGTCACTTTtcccatcagcagcaacagcaacaacagtcggCTATGAAGTACACGTATGCAACTACGTTGGCTCCACCACCTCCGCCTCTGCAGCTCTTTGCACAGCAGCCGACGACATCGCAGTCGCATCAGAAGCCACCGCCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCACAAccaaaacaagcaacagcaacaacatataaCCGTACAGCATAACGTTAACCTAGCACCACCGAGTGGGAAGCACAGTAAAGCCCACACGGAGATCTTTCTAAatccaccgccaccaccaccgccacagTCAACGATGCCGTCTTCGTCGACCTCCTCCTCAAGACTGCAACATTcacaacagcaccagcaatcCCTTGCAGCCGGTAGCAGCTATGCAACAgccagctgctccagctcctcaTCGAGCCTGATGTCAACGACAACCGGACGAGCCAGCAGTCGCCAATCGACCAATTCGCCATTTGGTGCACTGCTTAATGCGGCGGCGCAAGCGGCAAACTCCTCGCCCGCCTCCTCCGGTGCGTCTGTGCTGCGTTACGCTGAATCGCCAGTTGCTCACTATCTAGAGCGGGAGAATGGCGACTTTATTGTCCAAGAGACACCCAAGCACATTGTCGAATGCGTCGAGAAAGATGACGGCGAATTCTCAGTGATTGAGCGAATATATCAGTCGCCACCCAGCGTGTTGCACATACATGACGATGACGAAGAAGAGGAGGCACAGAGCTGGGCAAACAGCGACGACGAGGATCACGCAAAGACACATAATAATGTGGAGGATGGTGATGATGAGCGTGAGGACAGTCGCAGCAGAGTTGGCCTTAAGACGATAACGAAGAAGCCGCGTAAGACAAAATCGGGTGGCAGGATGCACAAACGCGCTCCTAAACATCAGATGAGAGCTACGGAGGATGAGGAAGAGTTCATGAGTGTGGGCAGCAGTGAAAACGAAGAACAGACAGAGGAGCAGCCGAAGCCGTCAGGTGGTGCACAGGTGGCGTCATCCTCTCTTCCGCAACTCTGCACGGCGCCTTCAACGAGCACTGGAGCTTCTCCTGCCACCTCTGGCATAGTTAATTCATCGTCCAACGCTACCATTAAGTCCAAAAAGAATCGCGTTACAGTTCTCAGCGATGTGCCGCTCAATATGAATGAGTATCTGGATCTGGTGGGCAACATTGTGGCTTCGAGCCGTATTGGTGCTGCTCGTCCGTTTGCCGCTGTGGCTCCCATTCCGTTGGTCAAAGTGGAAAAGGAGGAGCCGCTGGACGAATACGATAGCGTTCAGACAGAGATTCCATCTATGGAACAGAAGCCTAGCCTGGAACAtgtcagcggcagcagcagtagcagcagcaatagtagtagcagcaaTGGGCACGGCACCACCAGCGTCATACGCATGGCCAGCACAAGCAGTAGTGTCAATGTTCCGGCCGAGGATCTCACACAGCCGCTGCCAATGAAAGTCGAAGTAGAGCCAACAATGCTACTGCCACAGCGCTTCTCAGCACCGGCGCAGCAGCGTGGTCCCAAGAAATTAGTCATCAAACCAAAGGCCACGGCAATGGCGACGGCGACCGCAcctgcgactgcgacgacgACTAAAAAGACTGATAACAATGCTGCCAGCATGAGAAGCAGTAACTGCGCCGAATCTCTCAGCATATCAAAAGCATCTGCAGAACTGGTGCAGATCAAAAGCGAGAATATGGAACCGTCCACATCAAGTGGAAGCATCCTAGAGAAGCATCTGACCACCAGCTTTAGTAGCCAACAAGCACGCAAGCACTCCACAGTCAACGACGACGATGCGCGCGTGCTGCTTGAGTTTGCTAACTCGAAGCAACTACCCCTAGCGGGAACCAGCAATCCCACAACATTTGTGGTGAATGCGGCCAGTTTTGCTTCGGCGGGCTCCGTATTTGCCAACAACTTGCAGAAGCCCATCAATCCGGGTGACGAGTACATTCTGCCTGATGATAATAAAGTGGAAATGGATGAAATTGTGATATCCTCCTCGTCTTCCTTTGCCTCCTCCAcgcagcaaccgcagcagcagcatcaacaggcAGCGCCGCCAGTTCAAGCATCGCACTCGGCATTGCAGCAGGCACAGCCGCCTACGTTCAATGACTTCAACTTTCTGTACCACCAAAATACAACGACTCCGACGGCTTCCAACTTTGCCCCATTCGGtcttcaacagcagcagcaacaacacggcTCCAGCGAAGCCACCAATGCAGCGACACTTGCATCTTCCTCCAGCAACTCGTCAGCATTAGATCACGACTCCTCCATGAATGCAACGTTCCGCGTGGCCAAGCCACAGTCATCGCTGAGTGCCTGGTatcagccacagcaacaggaggagcagcagcaggaacaacaacaccagccaCAACCGACTACCTCTCAGAACGTGGAACAGTCGAGCAATTTTATTGCAGCACTGGCAGCCGTCGATTGCTGCAGTGTGGCGATGGACAGTGACGCGAGTGATGCAAAGTACTTGGATCTGGATGCATGCAAGCGGGAACAGTtgagcaatagcagcagccaTTTGCCCTCTGCCTCGGCATCCACGTCCACAACATCGTCTTCATTTGCTGCCGCAGCGACAGAGAGCAGCCTCGTTGGTGGTCTGGGATTAAACATTCGAACTGATGAGAAGATGCCCGCGAAGGGTGAAATTTCTGAGCAGGAGAGCAACTGCGACATTGAGAACTCTTGGAGTCAATCGATGTATGGGGACATATCCCAGCGGTACTTTAGAAACCAGTTTGCGGATGGCTACAATCAGCAGCTGACAGAATGGCGTCAGGACTATTATCCTGCGCAGGATCTCAgtggtcagcagcagcagcgtgagCACAAACGTTTCGATTTCAATACGGTCGCTTCCGAGTATGCACAACCGGGTGAGCTGGACGCCTCCTCGAGCTCTGCTAGAAGCAATCAATTGTTGGATCTACAGCCCACCACGTCCACATCGTCATCGGCTTTGCTGGCTGGTCCACCAATAGCCTCGACATCCAGAGCTGCCGCCGAAGCGGAAGCAGTCGCTGCAGCGTTGCAGCGCAAGCCCGCGCGTCGCAAGATCTACAAGTGTCCACACTGCGTGGCCATCTTTGAGAAGCTAAAGGAGCGCAATGCGCATATGATTGGAGAGCATAACTATGTGCGTCAAAATCGCCGACTCATCTGCACGCAGGCGTTGGTCAACGCCGCTATGTTATCACAGCCACAGGttcaccaacaacagcagcagcagctgctgatgcaAGCAGGTGGCAGCATTAGCGAAGCCCTGCAAGAAGATTCCAAAGATGGCATTGTGAAGATCAAACAGGAGCACTGCCAGGACAAGCCCGATTCATCGGAGCAGCTGCTCGATCATTTGGAGCTGCCGGATGTGAAAGATACAGACTTATTAGACGTTAATGGTGTTAACATACGTGATGCGGACATGAAGCCTTCCACCAACGTGACTGATTTGAAGCCCACTATGACGCCGTTGGCTATGACCACACCGGCTGCCAAGTTGGCGGCTATTTACCGCATGCTCATTGCCTACAATGAGTCGAAACTTGGACAGGATCATCACAATCTCAGCGAACTGGAGCAAAAGGCAATGGAGAAATCCATATTTTTATGCTACGTCTGTCGCACCGATTTCCCCTCTGTGAAGTTGTACGATGCACATCTCACTGAGCATCCTGCCGAGTGCTTCACCTGTGGCAAGAAATTCTATCGCTGGAAAAATTTCTCACTGCATCTGAAACGTCATCTCGGCTGGAAGGAGTTCGGCTGCTATGTCTGCGATAAGAAATTCGTTGTGCGCAGTGCCCTGGTCGAGCATATGCGGATGCACACTGGCCAAACCCCGTTGAAGTGTAAAATCTGCGGTAAAAAATTCAAGCGTTACTCCAACTTGACTCAGCATCGGAAGCGGCACACCAAAATGACGGTGAGGAAAAAGGAATATGTGTGTCACTGCGGCGAGGTGTTGCCTTCGAAAGCGCGTTTCCTGTGGCATAAAGAAACGCATGATTTGAAGCCCAAGTGCTGTCCGTACTGCTGCGATCGTTTTGTGCATGCAAATTCACTGCGCCGACACATCCGGCTGGCACATTCGGATAAGTTTGACTATGCTGAGCCCATGGAATGCCCCATGTGCAAGCAGATTTTCGCCAAAACGTCCATTAAGGCACACATGGCCACGCACTCGACGGATCCCCAATACGATTGCGCCATCTGCAATAAGAGCTTCTCCACAAAATGGAATCTCAAGATACATTCGTGGGTGCACGCCAATCGCACCGCCAAGCCGTTCAAGTGCGAGTACTGCCCCAAAGCCTTTGTACGGGAGCTCGATTTCAAGAACCACATGAATGCGCACAAGCAGATTAAGCCCTATACCTGCGAATACTGTGGTTGCAAGTTCATACGAAAGTACAATTACATGCGGCATCGACGAGAGCACCATGGCAACAAGAAGTTCACCTGCGACCAGTGCGACAAATCTTTTCATCGGCACTACTATCTGATTGAGCATCGGCGCATTCATACTGGAGAACGGCCTTTCCATTGCACCATCTGCGGCAAGAGCTCGACGACAAAGACCAATCACAACAAGCATCTGAAGATACATCATTCGCGAGATCCTTTTACCGTGGAGGTTTAA
- Protein Sequence
- MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGSNAIGGALVAAALSTAGSGASSDGASSSSPPETDVKPAVAATATAPSAVAAAAPAAATTAAHPPPPPPTPTATPTTTTTLKSTAPKAASLLGNASSNSSNNSNSNNNKLSNPPIKAVKSAPPSTEASATTSITPTISSVAAAYPPSLTSDYRYDQQHQQQQQQQTPPPATLHGFPRGATTMLVIPQATQQQHHFLATQQPGHFSHQQQQQQQSAMKYTYATTLAPPPPPLQLFAQQPTTSQSHQKPPPAYGAAISQIRSQHNQNKQQQQHITVQHNVNLAPPSGKHSKAHTEIFLNPPPPPPPQSTMPSSSTSSSRLQHSQQHQQSLAAGSSYATASCSSSSSSLMSTTTGRASSRQSTNSPFGALLNAAAQAANSSPASSGASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEAQSWANSDDEDHAKTHNNVEDGDDEREDSRSRVGLKTITKKPRKTKSGGRMHKRAPKHQMRATEDEEEFMSVGSSENEEQTEEQPKPSGGAQVASSSLPQLCTAPSTSTGASPATSGIVNSSSNATIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPLDEYDSVQTEIPSMEQKPSLEHVSGSSSSSSNSSSSNGHGTTSVIRMASTSSSVNVPAEDLTQPLPMKVEVEPTMLLPQRFSAPAQQRGPKKLVIKPKATAMATATAPATATTTKKTDNNAASMRSSNCAESLSISKASAELVQIKSENMEPSTSSGSILEKHLTTSFSSQQARKHSTVNDDDARVLLEFANSKQLPLAGTSNPTTFVVNAASFASAGSVFANNLQKPINPGDEYILPDDNKVEMDEIVISSSSSFASSTQQPQQQHQQAAPPVQASHSALQQAQPPTFNDFNFLYHQNTTTPTASNFAPFGLQQQQQQHGSSEATNAATLASSSSNSSALDHDSSMNATFRVAKPQSSLSAWYQPQQQEEQQQEQQHQPQPTTSQNVEQSSNFIAALAAVDCCSVAMDSDASDAKYLDLDACKREQLSNSSSHLPSASASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFADGYNQQLTEWRQDYYPAQDLSGQQQQREHKRFDFNTVASEYAQPGELDASSSSARSNQLLDLQPTTSTSSSALLAGPPIASTSRAAAEAEAVAAALQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVNAAMLSQPQVHQQQQQQLLMQAGGSISEALQEDSKDGIVKIKQEHCQDKPDSSEQLLDHLELPDVKDTDLLDVNGVNIRDADMKPSTNVTDLKPTMTPLAMTTPAAKLAAIYRMLIAYNESKLGQDHHNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00586145; iTF_00602019; iTF_00510726; iTF_00519366; iTF_00595468; iTF_00558114; iTF_00589770; iTF_00583886; iTF_00507088; iTF_00562674; iTF_00534036; iTF_00523159; iTF_00585400; iTF_00520857; iTF_00614414; iTF_00509314; iTF_00608633; iTF_00529019; iTF_00553917; iTF_00472574; iTF_00575807;
- 90% Identity
- -
- 80% Identity
- -