Basic Information

Insect: Drosophila testacea
Gene Symbol: -
Assembly: GCA_035043265.1
Location: JAWNND010000211.1:1580952-1587672[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.051 3.9 8.3 0.2 1 23 1316 1339 1316 1339 0.94

2 13 8.3 6.3e+02 1.4 0.2 1 23 1504 1526 1504 1526 0.91

3 13 0.00018 0.014 16.0 2.7 2 23 1529 1550 1529 1550 0.97

4 13 7.1e-05 0.0054 17.3 0.2 3 23 1558 1578 1556 1578 0.98

5 13 5.9e-07 4.5e-05 23.9 4.1 2 23 1585 1606 1584 1606 0.97

6 13 5.3 4e+02 2.0 0.4 5 23 1619 1637 1616 1637 0.95

7 13 1.4 1.1e+02 3.8 5.4 3 23 1644 1665 1642 1665 0.93

8 13 0.15 11 6.9 0.2 2 23 1676 1696 1675 1696 0.96

9 13 5.7e-05 0.0043 17.6 0.4 1 19 1702 1720 1702 1724 0.95

10 13 1.6e-05 0.0012 19.4 0.5 1 23 1732 1754 1732 1754 0.98

11 13 0.00011 0.0081 16.8 7.6 1 23 1760 1782 1760 1783 0.96

12 13 0.00021 0.016 15.9 5.9 1 23 1788 1810 1788 1810 0.98

13 13 0.029 2.2 9.1 8.2 1 23 1816 1838 1816 1839 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.051	3.9	8.3	0.2	1	23	1316	1339	1316	1339	0.94
2	13	8.3	6.3e+02	1.4	0.2	1	23	1504	1526	1504	1526	0.91
3	13	0.00018	0.014	16.0	2.7	2	23	1529	1550	1529	1550	0.97
4	13	7.1e-05	0.0054	17.3	0.2	3	23	1558	1578	1556	1578	0.98
5	13	5.9e-07	4.5e-05	23.9	4.1	2	23	1585	1606	1584	1606	0.97
6	13	5.3	4e+02	2.0	0.4	5	23	1619	1637	1616	1637	0.95
7	13	1.4	1.1e+02	3.8	5.4	3	23	1644	1665	1642	1665	0.93
8	13	0.15	11	6.9	0.2	2	23	1676	1696	1675	1696	0.96
9	13	5.7e-05	0.0043	17.6	0.4	1	19	1702	1720	1702	1724	0.95
10	13	1.6e-05	0.0012	19.4	0.5	1	23	1732	1754	1732	1754	0.98
11	13	0.00011	0.0081	16.8	7.6	1	23	1760	1782	1760	1783	0.96
12	13	0.00021	0.016	15.9	5.9	1	23	1788	1810	1788	1810	0.98
13	13	0.029	2.2	9.1	8.2	1	23	1816	1838	1816	1839	0.95

Sequence Information

Coding Sequence: ATGGTTGACAGtgtgcagtgccccgtgtgcACCTTGTACCTGCACGCGGGCATGAATCTCTCAGATCACTTGGAGACCCATCCCAAGGAACAAGTGATCAAAGCCCTGGTGCAAATGACAATCGCTGGCAACAATGCATTGGGCGGCGCCCTGGTGGCAGCTGCACTCTCCACTGCCGGCAGTGGTGCATCATCAGACAGCGCCGCCTCCTCCTCTTCCCCAACAGCGGCTGATTCAGATGTGAAACcagttgtggcagcaacagcaacagtagctacagcagcagcaccaacgccaccatcaccaccacagccaccaataacaacagcaacattaaaaTCAACAGCACCCAAGGCAGCATCATTGCTGGGAAAtacaagtaacaacaacagcagtaacagtagcaacagtaacaataacaaattgagCAATCCACCGATTAAGGCAGTTAAAAGCGCGCCAACCTCGACTGAGGCGTCAGCCACCACATCCAACACACCCACCATAAGCAGCGCAGCCGCTGCCTATCCTCCATCGTTGACATCCGACTATCGCTAtgatcagcagcaacagcagccacaacaacagcagcagcagcaacaggcgaCGCCAACGGCAACGCTTCATGGCTTTCCACGTGGAGCAACCACAATGCTAGTGATACCACAtgcaccacaacaacagcagcatcattTCCTGGCCACCCAACCACCGCCTGGTCACTTTAcccatcagcagcaacagcaacagcaacagcaaacacaGTCGGCTTTGAAATACACGTATGCAACAACgttgccaccaccaccgccgcctTTGCAGCTCTTTGCACAGCAGCCGACGACTTCGCAGTCACATCAGAAGCCACCGCCCGCCTATGGCGCAGCCATCAGTCAAATTCGATCTCAGCACAACCaaaacaagcaacagcagcaacaacaacatataacCCTGCAACATAATGTTAACCAAGCACCACCGAGTGGGAAGCACAGCAAATCCCTTACGGAGATTTTTCTGAATCCACCGCCTCCACCACCGCCACAGTCGACCTCCTCTGCATCCGCATCGGCATCCGCATCGGCATCCGCATCGGCATCCGCATCCTCCTCCTCAAGACTGCAACATccacaacagcatcagcaatcCCTTACAGCCGGTAGCAGCTACACTCCAGCTAGTTGCTCCAGCTCCTCATCGAGCCTGTTGTCATCGACAAGCGGACGAGCCAGCAGTCGTCAAACGACAAATTCGCCATTTGGTGCACTGCTTAATGCGGCGGCACAAGCTGCCAGCTCCTCGCCCGCCTCCACTAGCGCATCTGTGTTGCGTTATGCCGAATCGCCGGTTGCCCACTATCTGGAGCGGGATAATGGTGACTTCATTGTTCAAGAAACGCCCAAACACATTGTGGAGTGTGTCGAGAAAGATGATGGAGAGTTCTCGGTCATTGAGCGCATCTATCAGTCGCCACCCAGCGTGTTGCACATACACGACGATGACGAAGAAGAGGAGGAACAAAGCTGGGCAAACAGCGAAGATGAAGATCACGCAAAGGCGGATAATAATGTGGAGGATGGCGATGATGAGCGTGAGGACAGTATCAGCAGAGTTGGCCTTAAGACAACAACGAAAAAGTCGCGTAAAACCAAATCGAGTGGCAGATTGCACAAACGCGCGTCTAAACATCAGATAACTACTACGGAGGATGAGGAAGAGTTCATGAGTCTGGGCAGCAGTGAGAACGAAGATCAGGCAGAGGAAGAACTGCAGTCTTTAGGTGATGCACAGGTTGTGTCACCAACTCCTCCACAACTTTCCACGGCGCCTTCTACGAGCAGTGgagctgctgcaactgcagcagctgctggcaATGTCAGCTCCACGTCAAGTGGTACCATCAAGTCGAAAAAGAATCGCGTTACAGTTCTGAGCGATGTGCCGCTCAATATGAATGAGTATCTGGATCTGGTGGGCAACATTGTGGCATCTAGCCGCATTGGGGCAGCTCGTCCATTTGCCGCTGTGGCACCCATCCCCTTGGTCAAGGTGGAAAAGGAGGAACCGCTGGACGAGTATGACAGCGTTCAGAACGAGATGCAATCTGTGGAACAAAAGCCCAGCCTAGAACATGCCAGTggcagcagtagcagtagtagcagcagcagtagcagcaatgGACATGGCACCACCAGCGTCATTCGGATGGCCAGCACAAGCAGTAGTACCAATGTTCCGCCCGAGGATCTCACACAGCCGCCGCCAATGAAAGTTGAGGTAGAGCCAAcgatgttgttgccacaacgCTTCTCAGCACCGGCTCAGCAGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCACAGcaacggcgacgacgacgactacGAAAAAGACTGATAATAATGCTGCCGGCGTCGGCGTGAGCGTCAGAAGCAACAACTGCGCCGAATCTCTTAGCATATCAAAGGCATCTGCAGAACTGGTGCAGGTCAAGAGCGAGAATGTGGAACCGTCCACATCGAGTGGTAGCATTCTAGAGAAGCATCTGACCACCAGCTATATTGGTCAACAAGCACGCAAACACTCCACAgtcaatgatgatgatgctcgTGTGTTGCTTGAATTTGCCAACTCGAAACAAATACCATTggcaggcagcagcagcaatcccACAACATTTGTGGTGAATGCGGCCAGTTTTGCATCGGCGGGATCAGTATTTGCAAGCAACATGCAGAAGCCAATCAAACCGGGTGACGAGTACATTTTGCCAGATGATAACAAAGTGGAAATTGATGAAATTGTGATATCCTCTTCGTCTTCCTTTGCCTCCTCCACGCAGCAaccgccgcagcagcagcatcagcagcatcaacacCATCAACAGGCAACTTTGGCAGTTCAAGCCCAGCACTCGACGTTGCAACAGACACAGCCACCTACGTTTAATGACTTTAACTTTCTGTACCAccaaaatgcaacagcaacaacgacaccGGCGGCTTCCAGCTTTACGCCTTTCGGCcttcagcaacagcagcaacagcagcaacaacaacaacacggtTCCAGCGAAGCCACCAACGCAGCGACGCTCGCCTCGTCCTCGAGTAACTCGTCAGCATTGGATCACGACTCCTCCATGAATGCAACGTTCCGCGTGGCCAAGCCGCAGTCATCGCTGAATGCCTGGTATCAGccacagcatcaacagcaacaggaacaacagcaTCCACAGCCAACAACCTCCCAGAATGTGGAACAGTCGAACAATTTCATTGCAGCATTGGCAGCCGTCGATTGTTGCAGTGTGGCGATGGACAGTGATGCAAGTGATGCCAAGTACTTGGATTTGGATGCATGTAAACGGGAACAGTTgagcaatagcagcagccaTTTGCCCTCTGCCTCGGCATCCACGTCCACAACATCGTCTTCATTTGCTGCTGCAGCCACAGAAAGTAGCCTTGTTGGTGGTCTAGGATTAAACATTCGGACGGATGAGAAGATGCCTGCCAAAGGGGAAATTTCCGAGCAGGAGAGCAACTGCGACATTGAGAACTCCTGGAGTCAATCGATGTATGGAGACATATCACAGCGGTACTTTAGAAACCAGTTTGCGGATGGTTACAACAATCAACAGCTGACCGATTGGCGTCAGGACTATTATCCTGCGCAGGATCTCAGtggtcagcagcaacagcgagaGCACAAACGTTTTGACTTTAATGCGGTCGCCTCCGAGTACGCGCAGCCAGGTGAACTGGACGCCTCTTCGGGCTCTGCAAGGAGCAATCATTTGCTAGATGTGCAACCCACCACGTCCACGTCGTCTTCGGCTTTGCTGGCTGGCCCACCAATAGCCTCGACATCCAGAGCTGCCGCCGAAGCGGAGGCAGTCGCTGCAGCGCTGCAACGAAAACCCGCACGTCGAAAGATCTACAAGTGCCCACACTGTGTGGCCATCTTTGAGAAGCTAAAGGAGCGCAACGCACACATGATTGGAGAGCACAACTATGTGCGTCAGAATCGCCGACTCATTTGTACGCAAGCATTGGTCAATGCTGCCATGTTAGCACAGCCGCCGgttcaacaacagcagcaccagcagcaacagcaacaacaacaactgttgctgcaGGCAGGTGGAAGCATTAGCGAAGCTTTGTATGAAGATTCCAAGGATGGCATTGTAAAGATCAAACAGGAGCAGTGCCAGGACAAACCCGATTCATCGGAACAGCTGCTTGATCACTTGGAGCTGCCGGATGTGAAAGATGCAGTCTTATTAGACGTTAACGCTGAGAACAGACCTGATGCGGACGTGAAACCTTCTACCAACGTGGCTGATCTGAAGCCGACCCTGGCGCCGTTGGCAATGACCACACCGGCTGCCAAGTTGGCAGCTATCTATCGGATGCTCATTGCCTATAATGAGTCAAAGCTTGGACAGGAGCATCACAACCTCAGCGAGCTGGAGCAAAAGGCCATGGAGAAATCTATATTTCTATGCTACGTCTGTCGCACCGATTTCCCCTCTGTTAAGCTTTACGATGCACATCTCACCGAGCATCCCGCCGAATGCTTCACCTGTGGCAAGAAATTCTATCGCTGGAAAAACTTCTCACTGCATCTGAAACGTCATCTTGGCTGGAAGGAGTTCGGCTGCTATGTCTGCGATAAGAAATTCGTTGTGCGCAGTGCCCTCGTCGAGCACATGCGCATGCATACTGGCCAAACCCCGTTGAAGTGTAAGATATGCGgCAAAAAGTTCAAGCGTTACTCCAACTTGACTCAGCATCGGAAGCGTCACACCAAAATGACGGTGCGGAAGAAGGAATATGTGTGTCACTGTGGCGAGGTGTTGCCTTCGAAGGCTCGTTTCCTGTGGCATAAGGAAACGCACGATTTGAAGCCCAAGTGCTGTCCATACTGCTGCGATCGTTTTGTCCATGCCAATTCACTGCGCCGACACATTCGGTTGGCGCATTCGGACAAGTTTGACTATGCTGAGCCCATGGAATGCCCCATGTGCAAGCAGATTTTTGCCAAAACGTCCATCAAGGCACACATGGCCACGCACTCGACGGATCCGCAATATGATTGCGCCATCTGTAACAAGAGCTTCTCCACAAAATGGAATCTTAAGATACATTCGTGGGTGCACGCCAATCGCACCGCCAAACCGTTCAAGTGCGAGTATTGCCCCAAGGCCTTTGTACGCGAACTGGACTTTAAGAACCATATGAATGCGCACAAACAGATCAAGCCCTATACCTGCGAGTATTGTGGTTGCAAGTTCATACGTAAATACAATTACATGCGGCATCGACGAGAGCATCATGGCAACAAGAAGTTCACCTGCGATCAGTGCGACAAATCTTTCCATCGACACTACTATCTGATTGAGCATCGTCGCATTCACACTGGCGAACGGCCTTTCCACTGTACCATCTGCGGCAAAAGTTCGACCACGAAGACCAATCACAACAAGCATCTGAAGATACATCATTCGCGAGATCCCTTCACGGTGGAGGTCTAA
Protein Sequence: MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNALGGALVAAALSTAGSGASSDSAASSSSPTAADSDVKPVVAATATVATAAAPTPPSPPQPPITTATLKSTAPKAASLLGNTSNNNSSNSSNSNNNKLSNPPIKAVKSAPTSTEASATTSNTPTISSAAAAYPPSLTSDYRYDQQQQQPQQQQQQQQATPTATLHGFPRGATTMLVIPHAPQQQQHHFLATQPPPGHFTHQQQQQQQQQTQSALKYTYATTLPPPPPPLQLFAQQPTTSQSHQKPPPAYGAAISQIRSQHNQNKQQQQQQHITLQHNVNQAPPSGKHSKSLTEIFLNPPPPPPPQSTSSASASASASASASASASSSSRLQHPQQHQQSLTAGSSYTPASCSSSSSSLLSSTSGRASSRQTTNSPFGALLNAAAQAASSSPASTSASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEQSWANSEDEDHAKADNNVEDGDDEREDSISRVGLKTTTKKSRKTKSSGRLHKRASKHQITTTEDEEEFMSLGSSENEDQAEEELQSLGDAQVVSPTPPQLSTAPSTSSGAAATAAAAGNVSSTSSGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPLDEYDSVQNEMQSVEQKPSLEHASGSSSSSSSSSSSNGHGTTSVIRMASTSSSTNVPPEDLTQPPPMKVEVEPTMLLPQRFSAPAQQRGPKKLVIKPKATATATTTTTKKTDNNAAGVGVSVRSNNCAESLSISKASAELVQVKSENVEPSTSSGSILEKHLTTSYIGQQARKHSTVNDDDARVLLEFANSKQIPLAGSSSNPTTFVVNAASFASAGSVFASNMQKPIKPGDEYILPDDNKVEIDEIVISSSSSFASSTQQPPQQQHQQHQHHQQATLAVQAQHSTLQQTQPPTFNDFNFLYHQNATATTTPAASSFTPFGLQQQQQQQQQQQHGSSEATNAATLASSSSNSSALDHDSSMNATFRVAKPQSSLNAWYQPQHQQQQEQQHPQPTTSQNVEQSNNFIAALAAVDCCSVAMDSDASDAKYLDLDACKREQLSNSSSHLPSASASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFADGYNNQQLTDWRQDYYPAQDLSGQQQQREHKRFDFNAVASEYAQPGELDASSGSARSNHLLDVQPTTSTSSSALLAGPPIASTSRAAAEAEAVAAALQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVNAAMLAQPPVQQQQHQQQQQQQQLLLQAGGSISEALYEDSKDGIVKIKQEQCQDKPDSSEQLLDHLELPDVKDAVLLDVNAENRPDADVKPSTNVADLKPTLAPLAMTTPAAKLAAIYRMLIAYNESKLGQEHHNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537699;
90% Identity: iTF_00558114;
80% Identity: -